• Title/Summary/Keyword: safty

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Environmental and biological monitoring of workers exposed to methyl bromide through quarantine fumigation (방역작업자의 브롬화메틸(methyl bromide) 노출수준과 생물학적 모니터링)

  • Lee, Jong-Seong;Lee, Yong-Hag;Shin, Jae-Hoon;Choi, Jung-Keun;O, Cha-Jae;Jung, Ho-Keun
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.11 no.3
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    • pp.212-218
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    • 2001
  • This study was performed to estimate environmental and biological monitoring of workers exposed to methyl bromide through quarantine fumigation. Airborne methyl bromide and it's metabolites were analyzed by gas chromatography and ion chromatography, respectively. The results are as followings; airborne concentration of methyl bromide(TWA) was $2.08{\pm}1.56ppm$(N=8). Dispersion and setting/degas groups were $0.67{\pm}0.12ppm$(N=2) and $2.54{\pm}1.53ppm$(N=6), respectively. Bromide ion concentration in serum was $23.40{\pm}14.91mg/{\ell}$(N=10) in the exposed workers and $4.74{\pm}0.82mg/{\ell}$(N=21) in the non-exposed workers. Bromide ion concentration in urine was $35.56{\pm}26.89mg/{\ell}$(N=11) in exposed group and $6.62{\pm}2.31mg/{\ell}$(N=21) in non-exposed group. Good correlation was observed between concentration of serum and urine ($r^2$=0.890 p<0.01). No significant correlations of other determinants were observed. Calculated from a regressive curve, the biological half lifes of serum and urine were 10.7 and 5.9 days. In these results, biological monitoring of bromide ion of serum and urine provided useful information for evaluating exposure of workers to methyl bromide, so that an availability of bromide ion of biological samples was showed as biological monitoring indices for methyl bromide.

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A Study Based on Qualitative Research of Electrical Potal Service (전기 포탈 서비스(H-SCP)에 대한 정성적 소비자 조사)

  • Choi, Myeong-Il;Lim, Young-Bae;Kim, Gi-Hyun;Park, Chee-Hyun;Bae, Seok-Myung
    • Proceedings of the KIEE Conference
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    • 2007.04b
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    • pp.95-98
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    • 2007
  • 소비자들의 미래주택에 대한 요구 중 대부분은 좀 더 편리함과 안전함을 제공받고자 하는 것이다. 근래에 퓨전개념으로 시작한 전력IT 관련 기술개발을 시작으로 다양한 홈 디지털 서비스 제공방안이 제시되고 있다. 본 논문에서는 주택 내 전기안전 소비자 U&A 및 Needs를 조사하고, 전기 포탈 서비스(H-SCP) 컨셉에 대한 소비자 수용도와 Needs를 파악하였다. 이 소비자의 조사결과는 앞으로 전기 포탈 서비스의 연구 진행 방향에 중요한 기초자료가 될 것으로 기대된다.

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A preliminary Study on Regulatory Frameworks for Consumer Product Safty Policy (소비자상품안전을 위한 규제분석틀에 대한 기초연구)

  • 김용희
    • Journal of Families and Better Life
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    • v.7 no.2
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    • pp.213-223
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    • 1989
  • Decision frameworks for product safty policy are developed in theory and practice. Product characteristic approach and expected utility analysis are applied to situations involving risk and misinformation. Eight types of regulatory frameworks are explained and critiqued form practical purposes on behalf of consumer policy makers. Various international organizations and their roles are briefly reviewed.

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Polycyclic Aromatic Hydrocarbons Hazard Assessment of Shellfish due to Oil Spill Accidents (유류 유출 사고 해역에 서식하는 패류의 다환방향족탄화수소(PAHs) 위해도 평가)

  • Kim, Poong-Ho;Kim, Min-Jeong;Jo, Mi-Ra;Lee, Doo-Seog;Song, Ki-Cheol;Byun, Han-Seok;Cho, Kee-Chae;Park, Kwang-Jae;Jun, Je-Cheon;Yoon, Ho-Dong
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.43 no.3
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    • pp.211-216
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    • 2010
  • On 7 December 2007, about 12,547 kL of crude oil spilled from the Hong Kong registered tanker Hebei Spirit along the west coast of the Republic of Korea, including Taean-gun, Chungcheongnamdo Province. This study evaluated the safety of seafood collected from the coastal area polluted by the crude oil. The range of total polycyclic aromatic hydrocarbons (${\sum}PAHs$) at 22 stations was 3.9-37.1 ng/g. The concentration of ${\sum}PAHs$ was higher in oysters, Crassoatrea gias, than that in short-necked clams, Ruditapes philippinarum. Benzo(a)pyrene, a highly toxic PAH, ranged from 0.07-1.47 ng/g, which did not exceed the European Union regulatory limit for benzo(a)pyrene. The toxicity equivalent of benzo(a)pyrene in oysters and short-necked clams was 0.49-1.70 and 0.09-1.01 ng/g, respectively. The estimated life time cancer risk was very low, i.e., $1.31{\times}10^{-8}$ for the oysters and $6.9{\times}10^{-9}$ for the short-necked clams. The body burden of PAHs in bivalves originated mostly from petroleum contamination, but the levels was not sufficiently high to harm human health.

IRF-1-mediated IFN-γ enhancement of TRAIL-induced apoptosis (TRAIL 유도 세포사멸에 있어서 IFN-γ의한 증가 기전 연구: IRF-1과의 관련성)

  • Park, Sang-Youel;Seol, Jae-Won;Lee, You-Jin;Kang, Seog-Jin;Kim, In-shik;Kang, Hyung-sub;Chae, Joon-seok;Cho, Jong-Hoo
    • Korean Journal of Veterinary Research
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    • v.44 no.2
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    • pp.195-200
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    • 2004
  • Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF family and potent inducer of apoptosis. TRAIL has been shown to effectively limit tumor growth in vivo without detectable cytotoxic side effects. Interferon (IFN)-${\gamma}$ often modulates the anti-cancer activities of TNF family members including TRAIL. We previously reported that IFN-${\gamma}$ enhanced TRAIL-induced Apoptosis in HeLa cells without the unknown mechanism. In this study, we investigated whether IRF-1 involves in IFN-${\gamma}$-enhanced TRAIL-induced apoptosis. We exposed HeLa cells to IFN-${\gamma}$ for 12 hours and then treated with recombinant TRAIL protein. No apoptosis was induced in cells pretreated with IFN-${\gamma}$, and TRAIL only induced 30% apoptosis after 3 hours treatment. In HeLa cells pretreated with IFN-${\gamma}$, TRAIL induced cell death to more than 75% at 3 hours, showed that IFN-${\gamma}$-pretreatment enhanced HeLa cell death to TRAIL-induced apoptosis. To investigate the functional role of IRF-1 in IFN-${\gamma}$-enhanced TRAIL-induced apoptosis, IRF-1 was overexpressed by using an adenoviral vector AdIRF-1. IRF-1 overexpression increased apoptotic cell death and significantly enhanced apoptotic cell death induced by TRAIL when infected cells were treated with TRAIL. Our findings show that IFN-${\gamma}$ enhances TRAIL-induced apoptosis by IRF-1 in HeLa cells.

Research on the Favorite Design of Motocycle Suits (모터사이클 슈트의 디자인 선호도 조사)

  • 황승희;김여숙
    • Journal of the Korea Fashion and Costume Design Association
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    • v.5 no.1
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    • pp.73-83
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    • 2003
  • Out of a total of 437 subjects surveyed, 83.3 put on motocycle suits when they drive. Though the suits are not comfortable, many motocycle riders put them on for safty reasons. To protect a driver's body, motocycle suits should be patched with protective bands or safty pads in various areas like part of waist, backbone, pelvis and knees. The ratio of dissatisfaction with the preceding motocycle suits was great owing to inconvenience in washing and in posture, especially heavy suits. Their favorite suits were found to be linking or coupled types among two piece styles. Leather was shown to be the preferable material and they wanted designs which the protective bands, or pads can be attatched on each portion for needs of safty against impact but designed for comfort and ease of movenment.

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Proteome analysis of chickens fed with tissue culture medium waste after harvest of Korean wild ginseng (산삼 배양액을 급여한 육계에서 근육의 프로테옴 분석)

  • Seol, Jae-Won;Hwang, In Ho;Chae, Joon-Seok;Kang, Hyung-Sub;Ryu, Kyeong-Seon;Kang, Chun-Seong;Park, Sang-Youel
    • Korean Journal of Veterinary Research
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    • v.45 no.2
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    • pp.155-161
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    • 2005
  • Proteomics is a useful approach to know protein expression, post-translational modification and protein function. We investigated the protein expression pattern and identity in chickens fed with the tissue culture medium waste after harvest of Korean wild ginseng (TCM-KWG) (Panax ginseng). Two groups (n=60/group) of day old broiler chickens were administered with 0 (control) and 0.8% (treatment) TCM-KWG through drinking water. After 5 weeks, we examined the protein expression pattern of fibularis longus and superficial pectoral muscle by Two-dimensional electrophoresis analysis. Interestingly, TCM-KWG treatment significantly increased five spot's density, and markedly reduced five spot's density in the muscles. We identified 10 proteins (desmin, myosin light chain 1, heat shock 25 kDa protein, collapsin response mediator protein-2A, alpha enolase, vimentin, actin alpha 1, my023 protein, pyruvate kinase and troponin T) by the matrix-assisted laser desorption ionization time of flight (MALDI-TOF).