• 제목/요약/키워드: safety score

검색결과 1,003건 처리시간 0.025초

Comparative Analysis of Endovascular Stroke Therapy Using Urokinase, Penumbra System and Retrievable (Solitare) Stent

  • Choi, Jae-Hyung;Park, Hyun-Seok;Kim, Dae-Hyun;Cha, Jae-Kwan;Huh, Jae-Taeck;Kang, Myongjin
    • Journal of Korean Neurosurgical Society
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    • 제57권5호
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    • pp.342-349
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    • 2015
  • Background : Higher reperfusion rates have been established with endovascular treatment for acute ischemic stroke patients. There are limited data on the comparative performance of mechanical thrombectomy devices. This study aimed to analyse the efficacy and safety of the stent retriever device (Solitaire stent) by comparing procedure time, angiographic outcome, complication rate and long term clinical outcome with previous chemical thrombolysis and mechanical thrombectomy using penumbra system. Method : A retrospective single-center analysis was undertaken of all consecutive patients who underwent chemical thrombolysis and mechanical thrombectomy using Penumbra or Solitaire stent retriever from March 2009 to March 2014. Baseline characteristics, rate of successful recanalization (modified Thrombolysis in Cerebral Infarction score 2b-3), symptomatic intracerebral hemorrhage, procedure time, mortality and independent functional outcomes ($mRS{\leq}2$) at 3 month were compared across the three method. Results : Our cohort included 164 patients, mechanical thrombectomy using stent retriever device had a significant impact on recanalization rate and functional independence at 3 months. In unadjusted analysis mechanical thrombectomy using Solitaire stent retriever showed higher recanalization rate than Penumbra system and chemical thrombolysis (75% vs. 64.2% vs. 49.4%, p=0.03) and higher rate of functional independence at 3 month (53.1% vs. 37.7% vs. 35.4%, p=0.213). In view of the interrelationships between all predictors of variables associated with a good clinical outcome, when the chemical thrombolysis was used as a reference, in multiple logistic regression analysis, the use of Solitaire stent retriever showed higher odds of independent functional outcome [odds ratio (OR) 2.62, 95% confidence interval (CI) 0.96-7.17; p=0.061] in comparison with penumbra system (OR 1.57, 95% CI 0.63-3.90; p=0.331). Conclusion : Our initial data suggest that mechanical thrombectomy using stent retriever is superior to the mechanical thrombectomy using penumbra system and conventional chemical thrombolysis in achieving higher rates of reperfusion and better outcomes. Randomized clinical trials are needed to establish the actual benefit to specific patient populations.

경요도전립선전기기화술의 초기 임상경험 : 경요도전립선절제술 및 레이저 전립선절제술과의 비교 (Early Clinical Experience with Transurethral Electrovaporization of the Prostate for Benign Prostatic Hyperplasia: Comparison with Transurethral Resection of the Prostate and Visual Laser Ablation of the Prostate)

  • 김정현;문기학;정희창;박동춘
    • Journal of Yeungnam Medical Science
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    • 제15권2호
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    • pp.297-305
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    • 1998
  • 최근에 Roller loop electrode를 이용한 경요도전립선전기기화술에 관심이 집중되고 있다. 저자들은 전립선비대증에서 전립선전기기화술의 가치를 알아보기 위해 Roller loop electrode를 이용한 전립선전기기화술(TEVP, 17례)을 레이저전립선절제술(VLAP, 39례)과 전통적 경요도전립선절제술(TURP, 59례)과 비교 분석해 보았다. TEVP는 효과 면에서는 전통적인 경요도전립선절제술에는 미치진 못하지만 VLAP과는 유사한 효과를 보였으며 안전성면과 경제적인 면에서는 VLAP을 능가하는 치료법으로 사료된다. 본 연구가 적은 환자를 대상으로 10개월까지 관찰한 결과이고 경요도전립선전기기화술의 초기 경험이라 명확한 결론을 내리기에는 다소 성급한 면이 있으나 전통적인 전립선절제술에 비해 짧은 입원기간, 짧은 요도관유치 기간 및 적은 출혈 등을 보여주며 레이저 시술의 단점인 고가장비가 필요 없다는 점에서는 전통적 전립선절제술의 대체 술기로 높이 평가되어진다.

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Quality evaluation of local brand rice in rice exporting countries

  • Kwak, Kang Su;Yoon, Mi Ra;Cho, Young Chan;Lee, Choon Ki;Choi, In Duck;Kim, Mi Jung;Kim, Sun Lim;Kim, Wook Han
    • 한국작물학회:학술대회논문집
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    • 한국작물학회 2017년도 9th Asian Crop Science Association conference
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    • pp.254-254
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    • 2017
  • This study evaluated the grain quality of local brand rice from 6 major rice exporting countries which are anticipated to export their rice to Korea. Recently, with the end of the postponement of rice import tariffs in 2014, Korea is in a very easy environment to import foreign rice. Therefore, the quality evaluation of local brand rice in those countries is needed to secure the quality competitiveness of Korean rice, also to protect the rice industry in Korea. We provided total 38 local brand rice from USA(7), China(16), Australia(4), Thailand(3), Vietnam(5) and India(3), and 2 imported brand rice through MMA from USA and China to find out the status of the grain quality for each country. For the quality evaluation, we analyzed the physicochemical properties, milling and palatability-related characteristics. The amylose content on country average ranged from 24.4(India)~16.2%(Thailand). The protein content was 6.66% by overall average, and was higher in order of India(7.86), Australia(6.80), Vietnam(6.61), Thailand(6.59), China(6.28), USA(5.82). In Toyo glossiness value, it ranged from 75.7~45.2, and the figures in USA and China were the highest level. The head rice ratio ranged from 95.2~72.4%, and the figures in Thailand, USA and China were distinctly high. When we analyze the palatability of boiled brand rice with Chucheongbyeo as check variety by expert panelists, several rice brands from USA and China showed equal or better scores in shape, smell, taste, stickiness, texture and overall score, although most rice brands showed a tendency to decrease significantly in the taste characteristics compared with Chucheongbyeo. From the above results, it can be seen that the grain quality of USA and China rice is very competitive when imported into Korea. The results will provide basic information for the quality control of foreign rice which will be imported into Korea in the near future, also for the quality information which could be applied on the development of high-quality Korean rice varieties. Continuous monitoring about the foreign brand rice is advisable to improve the quality competitiveness of Korean rice.

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고령 환자군에 있어서 유리피판술을 이용한 두경부재건의 안전성 (The Safety of Microsurgical Head and Neck Reconstruction in the Elderly Patients)

  • 최봉균;김영석;이원재;유대현;탁관철
    • Archives of Plastic Surgery
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    • 제33권3호
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    • pp.289-293
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    • 2006
  • By means of microsurgical free-tissue transfer providing a large amount of required tissue, the surgeon can resect tumoral tissue more safely, which allows tumor-free margins and enhances the reliability of the ablative surgery that otherwise could not be performed radically. The morbidity of elective free-tissue transfer seems to be quite low, carrying acceptable risks for most patients. But the elderly patients are at risk for cardiac and respiratory problems, deep vein thrombosis, pulmonary emboli and infection merely as a function of age. This study was undertaken to define further risks of the elderly population with regards to free-tissue transfer. We retrospectively reviewed our experience with 110 microsurgical free-tissue transfers for head and neck reconstruction in patients greater than 60 years of age. Microsurgical procedures in all cases were preformed by the plastic and reconstructive department at Yonsei medical center. The investigated parameters were patient demographics, past medical history, American Society of Anesthesiologists(ASA) status, site and cause of defect, the free tissue transferred and postoperative complication including free-flap success or failure. There were 46 patients in the age group from 60 to 64 years, 34 patients from 65 to 70 years, and 30 patients 70 years or older. There happened 3 flap losses, resulting in a flap viability rate of 97%. Patients with a higher ASA designation experienced more medical complication(p=0.05, 0.01, 0.03 in each age group I, II, III) but not surgical complication p=0.17, 0.11, 0.54 in each age group I, II, III). And the relationship between postoperative complication and age groups was not significant. These observations suggest that major determinant for postoperative medical complication be the patient's American Society of Anesthesiologists score, and chronologic age alone should not be an exclusion criterion when selecting patients for free-tissue transfer

Grey System Theory를 이용한 차량 및 보행환경 통합평가 (Evaluation of Vehicle and Pedestrian Environments using Grey System Theory)

  • 이진각;손영태;한상진;박진영;이상화
    • 대한교통학회지
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    • 제28권4호
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    • pp.141-156
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    • 2010
  • 본 연구에서는 기존의 차량 및 보행환경의 평가에 있어서 종합적이고 통합적인 접근방식에 한계가 있다고 진단하고, 이를 고려하는 평가 방법 개발에 중점을 두었다. 여기에서의 통합적인 평가라 함은 차량환경과 보행환경에서 쓰이고 있는 수단별 평가 지표에 대한 통합과 더불어, 공간적 개념에서 선/축의 평가방식을 포함한 면적인 차원의 평가라 할 수 있겠다. 본 연구에서는 통합 평가를 위한 이론적 배경으로 Grey System Theory(GST)를 적용하였으며, 대상지역은 보행우선구역 시범사업지로 하여 차량 및 보행환경에 대한 평가를 수행하였다. GST에 의한 종합평가 및 분석결과, 같은 서비스수준 또는 상대적으로 차량 및 보행환경의 운영지표상(도로용량편람)에서는 보다 양호한 상태라 할지라도 관측된 데이터가 Grey Category 범위에 따라 통합 평가시에는 평가지표 간 가중치 등이 고려되어 산정되었기에 Category 상에서의 종합점수는 달라지는 것을 알 수 있었다. 이러한 점을 종합적으로 고려해 볼 때, 도로운영상의 지표들이 상대적으로 좋다고 하더라도 안전상의 지표들이 나쁠 경우에는 그에 따라Grey Category상의 점수들도 변화하는 것을 알 수 있었으며, 본 평가방법을 통해 향후 도시가로 형태별로 현재 상태를 진단할 뿐 아니라 노선별(축별), 면적인 개념에서의 평가와 더불어 평가지표간 통합평가가 이루어 질 것으로 기대하고 있다.

Effects of low-dose topiramate on language function in children with migraine

  • Han, Seung-A;Yang, Eu Jeen;Kong, Younghwa;Joo, Chan-Uhng;Kim, Sun Jun
    • Clinical and Experimental Pediatrics
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    • 제60권7호
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    • pp.227-231
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    • 2017
  • Purpose: This study aimed to verify the safety of low-dose topiramate on language development in pediatric patients with migraine. Methods: Thirty newly diagnosed pediatric patients with migraine who needed topiramate were enrolled and assessed twice with standard language tests, including the Test of Language Problem Solving Abilities (TOPs), Receptive and Expressive Vocabulary Test, Urimal Test of Articulation and Phonology, and computerized speech laboratory analysis. Data were collected before treatment, and topiramate as monotherapy was sustained for at least 3 months. The mean follow-up period was $4.3{\pm}2.7months$. The mean topiramate dosage was 0.9 mg/kg/day. Results: The patient's mean age was $144.1{\pm}42.3months$ (male-to-female ratio, 9:21). The values of all the language parameters of the TOPs were not changed significantly after the topiramate treatment as follows: Determine cause, from $15.0{\pm}4.4$ to $15.4{\pm}4.8$ (P>0.05); making inference, from $17.6{\pm}5.6$ to $17.5{\pm}6.6$ (P>0.05); predicting, from $11.5{\pm}4.5$ to $12.3{\pm}4.0$ (P>0.05); and total TOPs score, from $44.1{\pm}13.4$ to $45.3{\pm}13.6$ (P>0.05). The total mean length of utterance in words during the test decreased from $44.1{\pm}13.4$ to $45.3{\pm}13.6$ (P<0.05). The Receptive and Expressive Vocabulary Test results decreased from $97.7{\pm}22.1$ to $96.3{\pm}19.9months$, and from $81.8{\pm}23.4$ to $82.3{\pm}25.4months$, respectively (P>0.05). In the articulation and phonology validation in both groups, speech pitch and energy were not significant, and all the vowel test results showed no other significant values. Conclusion: No significant difference was found in the language-speaking ability between the patients; however, the number of vocabularies used decreased. Therefore, topiramate should be used cautiously for children with migraine.

Clinical Experience of the Dynamic Stabilization System for the Degenerative Spine Disease

  • Lee, Soo-Eon;Park, Sung-Bae;Jahng, Tae-Ahn;Chung, Chun-Kee;Kim, Hyun-Jib
    • Journal of Korean Neurosurgical Society
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    • 제43권5호
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    • pp.221-226
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    • 2008
  • Objective : The aim of the present study was to assess the safety and efficacy of the dynamic stabilization system in the treatment of degenerative spinal diseases. Methods : The study population included 20 consecutive patients (13 females, 7 males) with a mean age of $61{\pm}6.98$ years (range 46-70) who underwent decompression and dynamic stabilization with the Dynesys system between January 2005 and August 2006. The diagnoses included spinal stenosis with degenerative spondylolisthesis (9/20, 45%), degenerative spinal stenosis (5/20, 25%), adjacent segmental disease after fusion (3/20, 15%), spinal stenosis with degenerative scoliosis (2/20, 10%) and recurrent intervertebral lumbar disc herniation (1/20, 5%). All of the patients completed the visual analogue scale (VAS) and the Korean version of the Oswestry Disability Index (ODI). The following radiologic parameters were measured in all patients : global lordotic angles and segmental lordotic angles (stabilized segments, above and below adjacent segments). The range of motion (ROM) was then calculated. Results : The mean follow-up period was $27.25{\pm}5.16$ months (range 16-35 months), and 19 patients (95%) were available for follow-up. One patient had to have the implant removed. There were 30 stabilized segments in 19 patients. Monosegmental stabilization was performed in 9 patients (47.3%), 9 patients (47.3%) underwent two segmental stabilizations and one patient (5.3%) underwent three segmental stabilizations. The most frequently treated segment was L4-5 (15/30, 50%), followed by L3-4 (12/30, 40%) and L5-S1 (3/30, 10%). The VAS decreased from $8.55{\pm}1.21$ to $2.20{\pm}1.70$ (p<0.001), and the patients' mean score on the Korean version of the ODI improved from $79.58%{\pm}15.93%$ to $22.17%{\pm}17.24%$ (p<0.001). No statistically significant changes were seen on the ROM at the stabilized segments (p=0.502) and adjacent segments (above segments, p=0.453, below segments, p=0.062). There were no patients with implant failure. Conclusion : The results of this study show that the Dynesys system could preserve the motion of stabilized segments and provide clinical improvement in patients with degenerative spinal stenosis with instability. Thus, dynamic stabilization systems with adequate decompression may be an alternative surgical option to conventional fusion in selected patients.

간호사 특성에 따른 일혈예방 지식과 간호수행 (Nurses' Knowledge and Performance for Prevention of Extravasation at Peripheral Intravenous Therapy)

  • 정선아;최은희;이경수;정귀애
    • 한국산학기술학회논문지
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    • 제17권8호
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    • pp.183-191
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    • 2016
  • 이 연구는 간호사를 대상으로 일혈 관련 간호사의 지식 및 간호수행 정도를 파악하여 일혈과 관련된 심각한 손상으로부터 환자를 보호하기 위하여 수행하였다. 연구 대상자는 D시의 3개 대학병원과 2개 종합병원 그리고 항암치료가 많이 시행되고 있는 1개 전문병원에 근무하는 간호사 293명을 대상으로 하였다. 본 연구 결과에서 간호사들의 일혈 관련 지식은 $18.50{\pm}2.18$점이었으며 일혈약물은 주입한 때마다 혈액 역류를 확인해야 하는 문항에 대한 지식 점수가 가장 높게 나타났다. 대상자의 일혈예방 지식 점수와 간호수행 점수는 50세 이상, 기혼, 임상경력 10년 이상, 병원 일혈에 대한 관심이 있는 군에서 유의하게 높았다. 또한 일혈예방 지식점수는 병원 안전관리체계가 있었던 경우에서 간호수행 점수는 고학력, 책임간호사 이상, 내과계와 중환자실, 정맥주입 관련 교육경험이 있었던 경우에서 높게 나타났다. 결론적으로 간호사들의 일혈예방 행위를 증가시키기 위해서는 계속 교육을 통해 지식을 향상시킬 필요가 있으나 지식 향상 뿐 만 아니라 행위를 향상시킬 수 있는 프로그램의 개발이 필요하다. 그러므로 환자 안전 관리팀의 운영, 표준화된 프로토콜의 개발과 적극 사용을 위한 의료기관 차원의 지원이 필요하다고 본다.

다른 밀원에서 기원한 꿀의 전자코 분석 (Analysis of Various Honeys from Different Sources Using Electronic Nose)

  • 홍은정;박수지;이화정;이광근;노봉수
    • 한국축산식품학회지
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    • 제31권2호
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    • pp.273-279
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    • 2011
  • 전자코를 이용하여 아카시아 꿀, 잡화 꿀, 밤 꿀, 유채꿀, 사양 꿀, 목청 꿀, 기타 꿀을 대상으로 밀원에 따른 차이를 구분하였다. 그 결과 꿀 종류에 따라 뚜렷이 구분 가능하였으며 각기 다른 꿀을 혼합하였을 때 혼합 비율에 따라서도 구분 가능하였다. 0, 5, 10, 15, 20, 25, 30%의 사양 꿀을 목청 꿀에 혼합하였을 때 혼합비율이 증가함에 따라 41, 42, 43, 45, 46, 47, 48, 54, 56, 58, 60 amu의 감응도 값이 크게 나타났으며 판별함수분석한 결과 사양 꿀의 혼합비율이 증가함에 따라 DF1값이 양의 방향에서 음의 방향으로 일정한 경향을 보이며 뚜렷이 구분되었다(DF1: $r^2$=0.9962, F=490.6 DF2: $r^2$=0.9128, F=19.44). 이를 통하여 DF1값과 목청 꿀에 사양 꿀의 혼합 농도에 대해 DF1=-0.106$^*$(사양 꿀의 농도)+0.426($r^2$=0.96)와 같은 높은 상관관계식을 얻었다. 아카시아 꿀의 경우에도 목청 꿀과 유사하게 사양 꿀의 혼합비율이 증가함에 따라 41, 43, 45, 46, 47, 56, 57, 58, 59, 60, 61, 70 amu의 감응도 값이 크게 나타났으며 DF1과 사양 꿀 혼합 비율간에 높은 상관관계를 보이며 일정한 경향을 나타냈고(DF1: $r^2$=0.9957, F=396.64 DF2: $r^2$=0.9447, F=29.3) DF1=-0.112$^*$(사양 꿀의 농도)+0.434($r^2$=0.968)의 상관관계식을 갖는다.

도심거주 고령자의 주거환경 만족도 분석: 천안시를 사례로 (Analysis of Contentment of Residential Environment among the Downtown Residents, the Aged: Taking Cheonan City for example)

  • 임준홍
    • 한국콘텐츠학회논문지
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    • 제15권3호
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    • pp.114-122
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    • 2015
  • 본 연구는 천안시 도심에서 생활하는 고령자를 대상으로 충남사회지표 자료를 이용하여 분산분석, 군집분석 등 통계적 분석방법을 통해 주거환경 만족도를 분석하고, 향후 도심을 고령자가 선호하는 주거공간으로 만들기 위해 어떤 주거환경 항목을 우선적으로 정비하여야 하는가를 제시하기 위해 이루어졌다. 분석결과는 다음과 같다. 첫째, 도심에서 생활하는 고령자의 주거이동 의향은 전체 응답자의 6.9%로 대부분의 사람들은 주거이동 의향이 약한 것으로 나타났다. 둘째, 도심에서 거주하는 고령자의 전반적인 주거환경 만족도는 6.09점으로 다른 지역에 비해 높아 도심을 고령자 친화 공간으로 만들 수 있는 가능성이 높은 것으로 나타났다. 셋째, 남성과 고졸이상, 100만원 이상의 소득자, 1세대 가족형태를 가진 사람의 도심주거환경 만족도가 상대적으로 높은 것으로 분석되었다. 넷째, 주거환경 요소 중 문화와 교육요인, 근린 간의 교류와 신뢰, 교통사고 등의 만족도가 낮아 이를 개선하여야 한다. 특히 우선적으로 이웃 간의 신뢰와 교류가 확대될 수 있는 커뮤니티 기반시설의 확충이 필요하다. 그리고 상대적으로 도심주거환경에 불만족하고 있는 여성들을 도심으로 끌어 들이기 위해서는 교통사고와 범죄 등 일상생활 속에서의 안전성을 보다 강화하여야 한다.