• 한국지하수토양환경학회지:지하수토양환경
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• 제28권5호
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• pp.59-67
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• 2023

This review examined the current administrative policies and guidelines for management of reclaimed soils after remediation processes and proposed practical strategies to improve the potential value of the remediated soil as a resource. Three management practices are proposed to facilitate more efficient recycling of remediated soil; obligatory use, quality certification, and tracking of the remediated soils. If properly implemented in utilization of remediated soil, these strategies could contribute to enhancing public safety by assuring soil quality. Such administrative tools, for both suppliers and demanders, are expected to mitigate potential risks associated with the transactions of remediated soil. To enhance the quality assurance process, a soil quality certification combined with the soil health assessment index was proposed. The systematic integration of the suggested practices with soil health assessment can allow to produce optimal results, encompassing affordability, efficiency, and accessibility, which helps establishing more robust 'Remediated Soil Recycling Management System (RSRMS)'. Subsequent researches should be conducted to develop more effective policies that incorporate soil health assessment tools. The proposed management practices for remediated soil, coupled with soil health assessment, can be a pioneering effort to achieve such goals. By fostering an environmentally friendly policies, the sustainable utilization of remediated soil can be attained. Overall, the proposed strategies can provide a sound framework for responsible and sustainable soil management practices.

• 무역학회지
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• 제48권4호
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• pp.121-148
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• 2023

북극 해빙의 급속한 용해는 유럽과 아시아 사이의 실행 가능한 대체 해로로서 북극항로에 대한 관심을 증대시켜 왔다. 현재까지 북극항로의 기술적 실현 가능성, 안전성, 수익성, 환경 영향 등을 고려한 광범위한 연구가 진행되어 왔다. 북극항로는 국제 교역의 중요한 루트가 될 것이며, 무역 원활화를 위해서는 항만 효율성이 무엇보다 중요하다. 그럼에도 불구하고 북극항로의 중요한 위치해 있는 항만들, 특히 러시아 북극 항만들의 효율성 평가에 대한 연구가 제한적인 상황이다. 따라서 본 연구는 데이터 포락 분석(DEA) 모델과 Malmquist 생산성 지수를 적용하여 러시아 17개 항구의 운영 현황을 분석하고, 효율성을 평가하고자 한다. DEA 분석 결과, 주로 서부 지역에 속하는 항만들의 효율성이 높게 나타났으며, 특히 무르만스크와 바란데이와 같은 항구는 지속적으로 높은 효율성과 꾸준한 규모의 수익을 보여주고 있음이 규명되었다. DEA-Malmquist 모형 결과에 의하면 기술발전에도 불구하고 모든 항구에 대한 전반적인 자원 활용 효율성의 개선 정도가 상대적으로 적은 것으로 나타났다. 본 연구의 결과는 인프라 개발 계획 및 관련 정책 수립을 위한 기초자료를 제공하고, 북극항로 항만 당국에 실질적인 시사점을 제공한다.

• 국제학술발표논문집
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• The 4th International Conference on Construction Engineering and Project Management Organized by the University of New South Wales
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• pp.318-323
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• 2011

Illegal and unethical behaviors of the construction industry affect people's lives and health more than the same problems of the other industries. Among these behaviors, the construction industry is mostly criticized for bribery scandals. According to the survey of the Ministry of Justice in Taiwan over the past years, bribery cases involving public engineering projects and governmental procurements account for a rather large portion of the indicted corruption cases. Transparency International's "Bribe Payer Index" indicates people in construction-related industries are the most likely to pay bribes. Poor construction quality directly and indirectly caused by bribery poses a great threat to public safety, organizational reputation and economic development. However, there is a limited number of existing research on the bribery problem of the construction industry. This study is an empirical attempt to explore bribery intention and its affecting factors among the construction organizations in Taiwan by conducting a questionnaire survey. The theory of planned behavior was used in this study to build its research model (covering elements of attitude, subjective norm, perceived behavior control, and intention). Totally 431 valid samples were returned. To explore the factors affecting bribery intention, this study adopted Pearson's correlation analysis to discuss about the connections among the questionnaire respondents' attitudes to bribery, subjective norms, perceived behavior control, and bribery intention. A multi-regression analysis was then conducted to test if the planned behavior theory can effectively predict bribery intention. The research found (1) according to the results of Pearson's correlation analysis, the respondents' bribery intention, attitudes, subjective norms, and perceived behavior control are positively correlated with one another; (2) according to the results of the multi-regression analysis, bribery intention can be explained through attitudes, subjective norms, and perceived behavior control with an adjusted R² value of 0.591, meaning 59.1% of the bribery intention's variances can be explained through the three dimensions. In addition, each of the three dimensions has a significant influence on the respondents' behavior intentions.

• 한국터널지하공간학회 논문집
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• 제25권6호
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• pp.447-458
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• 2023

본 연구에서는 쉴드터널 세그먼트 라이닝의 하중과 부재저항의 확률적 특성뿐만 아니라 경계조건의 변동성을 고려한 비교모델을 선정하고 신뢰성해석을 수행하였으며, 파괴확률 산정 및 구조안전성 검토를 통해 한계상태설계의 적정성에 대해 분석을 수행하였다. 이러한 지반 정수의 확률특성치를 고려한 해석을 위해 지반스프링계수는 Muirwood식을 적용하여 정량적 값을 산정하여 Mean값으로 고려하였고, 변동계수는 기존 연구자료를 토대로 지반 경계조건 변화에 따른 검토대상 모델들을 선정하였다. 이러한 모델들에 대한 구조해석과 MCS기법을 적용한 신뢰성분석을 통해 파괴확률과 신뢰성지수를 산정하여 지반경계조건 변화에 따른 파괴확률의 변화를 검토하였다.

• 대한조선학회논문집
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• 제61권2호
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• pp.125-134
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• 2024

The Safe Operating Envelope (SOE) combined with Short-Take-Off and Vertical Landing (STOVL) performance is an essential consideration of a light aircraft carrier for design of hull shape with excellent seakeeping performance in terms of naval air operations as well as traditional naval ship missions such as Transit and Patrol (TAP), and Replenishment at Sea (RAS) and so on. A variety of procedures are systematically combined to determine SOE considering rather complicated missions associated with operation of aircraft onboard. The evaluation of take-off and landing safety missions onboard should consider wind effect on deck and severer seakeeping indices and standards compared with conventional naval ships. In order to support take-off and landing missions, various support activities of the crews are required. So, additional evaluation is needed for indicators such as MSI(Motion sickness Index) and MII(Motion Induced Interruptions), which are quantitative indicators of work ability that appear as a result of motion response. In this study, a standard procedure is developed including the seaworthiness performance indicators, standards, and evaluation procedures that should be considered during design of STOVL aircraft carrier. Analysis results are discussed in terns of air-wake on deck as well as seakeeping indices associated with design parameter changes in view of conceptual design of a light aircraft carrier.

• Geomechanics and Engineering
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• 제37권3호
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• pp.223-241
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• 2024

Evaluating the performance of Tunnel Boring Machines (TBMs) stands as a pivotal juncture in the domain of hard rock mechanized tunneling, essential for achieving both a dependable construction timeline and utilization rate. In this investigation, three advanced artificial neural networks namely, gated recurrent unit (GRU), back propagation neural network (BPNN), and simple recurrent neural network (SRNN) were crafted to prognosticate TBM-rate of penetration (ROP). Drawing from a dataset comprising 1125 data points amassed during the construction of the Alborze Service Tunnel, the study commenced. Initially, five geomechanical parameters were scrutinized for their impact on TBM-ROP efficiency. Subsequent statistical analyses narrowed down the effective parameters to three, including uniaxial compressive strength (UCS), peak slope index (PSI), and Brazilian tensile strength (BTS). Among the methodologies employed, GRU emerged as the most robust model, demonstrating exceptional predictive prowess for TBM-ROP with staggering accuracy metrics on the testing subset (R² = 0.87, NRMSE = 6.76E-04, MAD = 2.85E-05). The proposed models present viable solutions for analogous ground and TBM tunneling scenarios, particularly beneficial in routes predominantly composed of volcanic and sedimentary rock formations. Leveraging forecasted parameters holds the promise of enhancing both machine efficiency and construction safety within TBM tunneling endeavors.

• Clinical and Experimental Vaccine Research
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• 제12권2호
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• pp.156-171
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• 2023

Purpose: The development of vaccines that confer protection against multiple avian influenza A (AIA) virus strains is necessary to prevent the emergence of highly infectious strains that may result in more severe outbreaks. Thus, this study applied reverse vaccinology approach in strategically constructing messenger RNA (mRNA) vaccine construct against avian influenza A (mVAIA) to induce cross-protection while targeting diverse AIA virulence factors. Materials and Methods: Immunoinformatics tools and databases were utilized to identify conserved experimentally validated AIA epitopes. CD8⁺ epitopes were docked with dominant chicken major histocompatibility complexes (MHCs) to evaluate complex formation. Conserved epitopes were adjoined in the optimized mVAIA sequence for efficient expression in Gallus gallus. Signal sequence for targeted secretory expression was included. Physicochemical properties, antigenicity, toxicity, and potential cross-reactivity were assessed. The tertiary structure of its protein sequence was modeled and validated in silico to investigate the accessibility of adjoined B-cell epitope. Potential immune responses were also simulated in C-ImmSim. Results: Eighteen experimentally validated epitopes were found conserved (Shannon index <2.0) in the study. These include one B-cell (SLLTEVETPIRNEWGCR) and 17 CD8⁺ epitopes, adjoined in a single mRNA construct. The CD8⁺ epitopes docked favorably with MHC peptidebinding groove, which were further supported by the acceptable ∆G_bind (-28.45 to -40.59 kJ/mol) and Kd (<1.00) values. The incorporated Sec/SPI (secretory/signal peptidase I) cleavage site was also recognized with a high probability (0.964814). Adjoined B-cell epitope was found within the disordered and accessible regions of the vaccine. Immune simulation results projected cytokine production, lymphocyte activation, and memory cell generation after the 1st dose of mVAIA. Conclusion: Results suggest that mVAIA possesses stability, safety, and immunogenicity. In vitro and in vivo confirmation in subsequent studies are anticipated.

• 대한한방내과학회지
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• 제44권6호
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• pp.1118-1138
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• 2023

Objectives: Sarcopenia is an age-associated skeletal muscle disorder that can profoundly impact the health of elderly people. However, the efficacy of herbal medicine in sarcopenia is uncertain. This review aims to investigate evidence of the effect of herbal medicine on sarcopenia. Methods: We systematically searched 12 electronic databases for relevant randomized controlled trials (RCTs). Only trials that met the inclusion criteria were selected, and the characteristics of the included studies were extracted and synthesized in a narrative manner. The quality of the included studies was assessed using Cochrane's Risk of Bias (RoB) 2.0 tool. Results: 7 RCTs involving 672 participants with sarcopenia met the inclusion criteria. The intervention combining herbal medicine and conventional treatment (i.e., exercise, nutritional support) had a significant therapeutic effect compared with the conventional treatment, showing improvement in muscle strength (i.e., grip strength), muscle mass (i.e., appendicular skeletal muscle mass index), and physical function (i.e., gait speed, short physical performance battery, and timed up and go test). However, the methodological quality of the included RCTs was relatively low due to their high RoB, making it difficult to evaluate the efficacy of herbal medicine in sarcopenia. In terms of safety, several adverse events were reported. Conclusion: This review suggests that herbal medicine has a positive effect on muscle strength, muscle mass, and physical performance in elderly patients with sarcopenia, but there is a clear need for further research in this area.

• 한국간담췌외과학회지
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• 제27권1호
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• pp.40-48
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• 2023

Backgrounds/Aims: Timing of resection for synchronous colorectal liver metastasis (CRLM) has been debated for decades. The aim of the present study was to assess the feasibility of simultaneous resection of CRLM in terms of major complications and develop a prediction model for safe resections. Methods: A retrospective single-center study of synchronous, resectable CRLM, operated between 2013 and 2021 was conducted. Upper limit of 95% confidence interval (CI) of major complications (≥ grade IIIA) was set at 40% as the safety threshold. Logistic regression was used to determine predictors of morbidity. Prediction model was internally validated by bootstrap estimates, Harrell's C-index, and correlation of predicted and observed estimates. Results: Ninety-two patients were operated. Of them, 41.3% had rectal cancers. Major hepatectomy (≥ 4 segments) was performed for 25 patients (27.2%). Major complications occurred in 20 patients (21.7%, 95% CI: 13.8%-31.5%). Predictors of complications were the presence of comorbidities and major hepatectomy (area under the ROC curve: 0.692). Unacceptable level of morbidity (≥ 40%) was encountered in patients with comorbidities who underwent major hepatectomy. Conclusions: Simultaneous bowel and CRLM resection appear to be safe. However, caution should be exercised when combining major liver resections with bowel resection in patients with comorbid conditions.

• Geomechanics and Engineering
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• 제36권5호
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• pp.417-426
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• 2024

Shield tunneling method is widely used to build tunnels in complex geological environment. Stability control of tunnel face is the key to the safety of projects. To improve the excavation efficiency or perform equipment maintenance, the excavation chamber sometimes is not fully filled with support medium, which can reduce the load and increase tunneling speed while easily lead to ground collapse. Due to the high risk of the face failure under non-fully support mode, the tunnel face stability should be carefully evaluated. Whether compressive air is required for compensation and how much air pressure should be provided need to be determined accurately. Based on the upper bound theorem of limit analysis, a non-fully support rotational failure model is developed in this study. The failure mechanism of the model is verified by numerical simulation. It shows that increasing the density of supporting medium could significantly improve the stability of tunnel face while the increase of tunnel diameter would be unfavorable for the face stability. The critical support ratio is used to evaluate the face failure under the nonfully support mode, which could be an important index to determine whether the specific unsupported height could be allowed during shield tunneling. To avoid of face failure under the non-fully support mode, several charts are provided for the assessment of compressed air pressure, which could help engineers to determine the required air pressure for face stability.