• 한국식품위생안전성학회지
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• 제22권1호
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• pp.1-14
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• 2007

The term, "food safety", has traditionally been viewed as a practical science aimed at assuring the prevention acute illnesses caused by biological microorganisms, and only to a minor extent, chronic diseases cause by chronic low level exposures to natural and synthetic chemicals or pollutants. "food safety" meant to prevent microbiological agents/toxins in/on foods, due to contamination any where from "farm to Fork", from causing acute health effects, especially to the young, immune-compromised, genetically-predisposed and elderly. However, today a broader view must also include the fact that diet, perse (nutrients, vitamins/minerals, calories), as well as low level toxins and pollutant or supplemented synthetic chemicals, can alter gene expressions of stem/progenitor/terminally-differentiated cells, leading to chronic inflammation and other mal-functions that could lead to diseases such as cancer, diabetes, atherogenesis and possibly reproductive and neurological disorders. Understanding of the mechanisms by which natural or synthetic chemical toxins/toxicants, in/on food, interact with the pathogenesis of acute and chronic diseases, should lead to a "systems" approach to "food safety". Clearly, the interactions of diet/food with the genetic background, gender, and developmental state of the individual, together with (a) interactions of other endogenous/exogenous chemicals/drugs; (b) the specific biology of the cells being affected; (c) the mechanisms by which the presence or absence of toxins/toxicants and nutrients work to cause toxicities; and (d) how those mechanisms affect the pathogenesis of acute and/or chronic diseases, must be integrated into a "system" approach. Mechanisms of how toxins/toxicants cause cellular toxicities, such as mutagenesis; cytotoxicity and altered gene expression, must take into account (a) irreversible or reversal changes caused by these toxins or toxicants; (b)concepts of thresholds or no-thresholds of action; and (c) concepts of differential effects on stem cells, progenitor cells and terminally differentiated cells in different organs. This brief Commentary tries to illustrate this complex interaction between what is on/in foods with one disease, namely cancer. Since the understanding of cancer, while still incomplete, can shed light on the multiple ways that toxins/toxicants, as well as dietary modulation of nutrients/vitamins/metals/ calories, can either enhance or reduce the risk to cancer. In particular, diets that alter the embryo-fetal micro-environment might dramatically alter disease formation later in life. In effect "food safety" can not be assessed without understanding how food could be 'toxic', or how that mechanism of toxicity interacts with the pathogenesis of any disease.

• 대한방사선기술학회지:방사선기술과학
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• 제31권3호
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• pp.239-247
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• 2008

본 연구는 방사선사를 대상으로 신체 부위별 근골격계 질환의 유병률과 이런 증상에 영향을 주는 요인을 파악함으로써 방사선사의 직업성 근골격계 질환을 예방하고 관리하는데 목적이 있고 조사대상으로 대전광역시에 소재한 5개 종합병원의 현 근무부서에 1년 이상 근무하고 있는 방사선사 219명을 대상, 조사기간은 2007년 6월 13일부터 2007년 6월 27일까지였고, 설문지는 전체 방사선사 219명 중 180명에게 무작위로 배부하였으며, 그 중 143명을 분석대상으로 하였다. 조사는 자기기입식 설문서(self-administered questionnaire)를 이용하였고 조사 내용은 근골격계 자각증상부위 및 증상 유해 요인에 대해 구성해 보았다. 자각증상에 대한 조사는 미국의 국립산업안전보건연구소(National Institute for Occupational Safety and Health; NIOSH)에서 정한 근골격계 증상 기준을 근거로 한국 산업안전공단(2003)에서 작성한 근골격계 부담 작업 유해요인 조사지침(KOSHA code H-30-2003)의 근골격계 질환 증상조사표를 이용하였고 증상 유해 요인은 노동부 고시 2003-24의 11가지 부담 작업 기준을 가지고 유해 요인 조사 항목에 사용하였다. 분석 방법은 각 신체 부위별 증상에 영향을 주는 요인의 교차비를 계산하기 위하여 증상호소 유무를 종속 변수로 하고, 일반적 변수 및 다른 변수들을 보정한 상태에서 노동부 고시 작업 부담 11개 항목을 독립변수로 하여 로지스틱 회귀분석을 실시하였다. 다음으로 11개 항목 중 신체 부위별로 통계적으로 유의한 변수들만 선택하여 Forward Wald 방법을 이용한 다중 로지스틱 회귀분석을 실시하여 각 위험 요인의 교차비를 계산하였다. 통계분석은 SPSSWIN(버젼 12.0)통계 프로그램을 사용하였다.

• 한국산업보건학회지
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• 제30권2호
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• pp.205-212
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• 2020

Objectives: The purpose of this study was to identify the needs and improvement measures of the risk assessment system through a survey of asbestos abatement companies. Methods: This study prepared a questionnaire that includes improvement measures for the risk assessment system(six questions) and the necessity of a risk assessment system for asbestos abatement(one question). The questionnaire was sent to 2,170 asbestos abatement companies and returned by 83 companies(return rate = 3.8%). We conducted frequency analysis, ANOVA, and Chi-squared testing at the 5% significance level. Results: This study analyzed the survey results and identified six main opinions on the risk assessment system and improvement measures. First, giving an advantage to companies with a high grade(S and A grades) in public bidding and/or qualification screening showed a similar preference(agree: 50.6%, disagree: 49.4%). Second, 57.6% of the respondents wanted to allow air showers along with water showers for low risk asbestos work. However, 23.2% of the respondents asserted that only a water shower should be allowed since there is no scientific evidence supporting the removal of asbestos by air shower. Third, in order to prevent missing the enrollment of workers, simply submitting a change report should be allowed when any worker is changed (40.0%). Fourth, 43% of the respondents answered that they did not know how to calculate the proper number of negative pressure units. The reasons given were a lack of guidelines or standards(38.9%), inconvenience (36.1%), and absence of education(25%). Fifth, the respondents who were favorable toward the necessity of a risk assessment system gave higher scores compared to unfavorable respondents on the necessity of the management of workers' work history(favorable respondent = 3.96 out of 5, unfavorable respondent = 2.68) and the necessity of professional training for workers(favorable respondent = 3.71, unfavorable respondent = 2.56). Finally, the respondents favorable toward a risk assessment system showed higher scores on the awareness of calculating the proper number of negative pressure units(4.79) compared to unfavorable respondents(3.3). Conclusions: The opinions of asbestos abatement companies identified through the survey in this study can be usefully utilized as fundamental information to improve the risk assessment system.

• 한국산업보건학회지
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• 제34권2호
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• pp.166-178
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• 2024

Objectives: The 12 occupational exposure limits(OELs) for chromium and its compounds in Korea were set by applying the American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Values (TLVs). However, this is significantly different from the TLVs after the existing TLVs were integrated and withdrawn in 2018, so it is necessary to review the revision. Methods: Various documents related to chromium OELs were reviewed, including the ACGIH TLV Documentations for chromium and its compounds. A field survey was conducted targeting workplaces handling chromium and its compounds. Based on this, a revised OELs were proposed and a socio-economic evaluation was conducted. Results: The OELs for chromium compounds in Korea was first enacted in 2002, and in 2007, the OELs for chromium (hexavalent) compounds (insoluble) was lowered from 0.05 mg/m³ to 0.01 mg/m³. In 2008, the OELs for strontium chromate was newly established as 0.0005 mg/m³, and in 2018, the OELs for calcium chromate was newly established as 0.001 mg/m³. Total chromium and hexavalent chromium were measured for each of 6 samples at 2 welding sites, 4 plating sites, and 2 spray coating sites. When omparing the average of the results measured by ICP, a total chromium analysis method, and the analysis results by IC, a hexavalent chromium analysis method, only workplace 4 was the same, and total chromium was evaluated more, and total chromium was evaluated at 0.0004 to 0.0027 mg/m³. And hexavalent chromium was evaluated as non-detection ~ 0.0014 mg/m³. Amendment ①: The exposure standard for hexavalent chromium is not divided into water soluble, insoluble, chromium ore processing, and other hexavalent chromium compounds, and is integrated into 0.01 mg/m³, which is the level of chromium (hexavalent) compound (insoluble)., OELs for chromium (metal) and chromium (trivalent) compounds are integrated into chromium (trivalent) compounds, and the exposure level is maintained. Amendment ②: As in the amendment ①, the OELs are integrated, but the level is lowered to 0.005 mg/m³, which is the OELs of OSHA, and there is a grace period of 4 years. Amendment ③: As in the amendment ①, the OELs are integrated, but the level is lowered to 0.0002 mg/m³, which is the exposure standard of ACGIH, and there is a grace period of 5 years. Conclusions: Amendment ①: The change in the OELs is insignificant, so the cost required is small, and the benefit/cost ratio is greater than 1, so there is no problem in applying the amendment. Amendment ②: In all scenarios except chromium 6(insoluble), the benefit/cost ratio is greater than 1, so it is thought that there will be no major problem in applying the amendment. Amendment ③: Since the benefit/cost ratio is less than 1 in all scenarios, it is thought that the total social benefit that can be obtained when applying the amendment is not large.

• 한국환경보건학회지
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• 제28권2호
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• pp.109-116
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• 2002

The purpose of this study was to evaluate a new sampling and analytical method for the determination of airborne hexavalent chromium, Cr(Ⅵ), in a field plating operation. The procedures of this new method (Shin & Paik's Method) are as the following: Airborne hexavalent chromium is collected on polyvinyl chloride (PVC) filter according to the National Institute iota Occupational Safety and Health (NIOSH) Method 7600, and the filler sample is placed in a screw-capped vial and soaked with 2% NaOH/3% Na₂CO₃ solution immediately after sampling. The Cr(Ⅵ) sample is analyzed by ion chromatography/visible spectrophotometry (IC/VS) according to the U.S. Environmental Protection Agency (EPA) Method 218.6. The airborne Cr(Ⅵ) concentrations measured by this method were compared with those determined by three reference methods: One (NIOSH/EPA Method) consisted of sampling airborne Cr(Ⅵ) on PVC filters and storing the sample filters in strew-capped vials according to the NIOSH method, and analyzing Cr(Ⅵ) in samples using IC/VS according to the EPA method. The second method (Impinger Method/NaHCO₃) consisted of absorbing airborne Cr(Ⅵ) into 0.02 M NaHCO₃ solution in midget impinger, and analyzing the Cr(Ⅵ) in samples using IC/VS. The third method was the OSHA Method ID-215. Using these four different methods, lour replicates of air samples were collected at an electroplating process and analyzed simultaneously. Two-way ANOVA and paired t-test were used to test difference among values determined by the methods. There was no significant difference and a strong correlation (r²:0.99) between Cr(Ⅵ) concentrations measured by the Shin & Paik's Method and an impinger method (p>0.05). However, Cr(Ⅵ) concentrations determined by Shin & Paik's Method were significant1y different from those by the NIOSH/EPA Method (p<0.05) or the OSHA method (p<0.05). The Cr(Ⅵ) concentrations of Shin & Paik's Method were significantly higher than those of the NIOSH/EPA Method or the OSHA method. This result indicated that the Shin & Paik's Method may prevent Cr(Ⅵ) losses caused by reduction and give more reliable results of airborne Cr(Ⅵ) concentrations in work environments.

• 한국산학기술학회논문지
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• 제20권5호
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• pp.372-383
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• 2019

본 연구는 정신병원 간호사를 대상으로 낙상에 대한 지식, 태도 및 환자안전문화인식이 낙상예방활동에 미치는 영향을 파악하기 위한 목적으로 시도되었다. 연구방법은 부산광역시와 경상남도 지역의 7개 기관의 정신병원에 근무하는 간호사 153명을 대상으로 한 서술적 조사연구로, 2018년 3월 5일부터 2018년 3월 30일까지 자료를 수집하였다. 연구통계방법은 IBM SPSS/win 24.0 프로그램을 t-test, ANOVA 그리고 다중회귀분석을 이용하였다. 그 결과, 연구 대상자의 면허나 자격에 따라 낙상태도에 차이가 있었고, 교육수준이 높을수록 환자안전문화인식정도가 높았으며, 근무경력이 많을수록 낙상예방활동이 높았다. 그리고 환자안전문화인식이 높을수록 낙상간호에 대한 태도가 높았으며, 낙상예방활동이 높을수록 낙상태도와 낙상안전문화인식이 높은 것으로 나타났다. 연구대상자의 낙상에 대한 지식, 태도, 환자안전문화인식이 낙상예방활동에 미치는 영향을 다중회귀분석 한 결과, 낙상예방활동에 대한 설명력은 12.5%로 나타났다. 그러므로 정신병원 간호사의 낙상예방활동을 증진시키기 위해서는 계속적인 교육을 통해 지식을 확장하며 낙상태도를 변화시킬 수 있는 교육프로그램 개발 및 제공이 요구된다. 또한 병원조직 차원에서 안전에 대한 전반적인 인적, 제도적 환경의 변화 등 다방면의 지원이 요구된다.

• 한국환경보건학회:학술대회논문집
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• 한국환경보건학회 2002년도 춘계 국제 학술대회
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• pp.40.1-43
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• 2002

The purpose of this study was to evaluate a new sampling and analytical method for the determination of hexavalent chromium, Cr(VI) in mist from field plating operation. The Procedures of this new method (Shin & Paik's Method) are as the following: Airborne hexavalent chromium is collected on polyvinyl chloride (PVC) filter according to the National Institute for Occupational Safety and Health (NIOSH) Method 7600, and the filter sample is placed in a screw-capped vial and soaked with 2％ NaOH/3％ Na₂CO₃ solution immediately after sampling. The Cr(VI) sample is analyzed by ion chromatography/visible spectrophotometry (IC/VS) according to the U.S. Environmental Protection Agency (EPA) Method 218.6. The airborne Cr(VI) concentrations measured by this method were compared with those determined by three reference methods: One (NIOSH/EPA Method) consisted of sampling airborne Cr(VI) on PVC filters and storing the sample filters in screw-capped vials according to the NIOSH method, and analyzing Cr(VI) in samples using IC/VS according to the EPA method. The second method (Impinger Method/NaHCO₃) consisted of absorbing airborne Cr(VI) into 0.02 MN/sub a/Hco₃ solution in midget impinger, and analyzing the Cr(VI) in samples using IC/VS. The third method was the OSHA Method Id-215. Using these four different methods, four replicates of air samples were collected at an electroplating process and analyzed simultaneously. Two-way ANOVA and Paired t-test were used to test difference among values determined by the methods. There was no significant difference and a strong correlation (r/sup 2/=0.99) between Cr(VI) concentrations measured by the shin & Paik's Method and an impinger method (p＞0.05). However, Cr(VI) concentrations determined by Shin & Paik's Method were Significantly different form those by the NIOSH/EPA Method (p＜0.05) or the OSHA method (p＜0.05). The Cr(VI) concentrations of Shin & Paik's Method were Significantly higher than those of the NIOSH/EPA Method or the OSHA method. We concluded that the Shin & Paik's Method could prevent Cr(VI) losses caused by reduction and give more reliable results of airborne Cr(VI) concentrations in work environments.

• 스마트미디어저널
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• 제11권9호
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• pp.30-38
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• 2022

안전사고의 위험성이 상존하는 작업 현장에서 안전사고 발생 시 신속한 조치를 위해서는 생체 데이터를 실시간으로 파악하는 것이 중요하다. 그 중 혈중산소포화도는 인간이 생명을 유지하는 데 있어서 가장 중요한 요소이므로 작업자의 안전관리를 위한 선제 대응으로 상황에 따라서 실시간 산소포화도 측정과 모니터링이 필요하다. 건강 및 생명 위험 보호복을 착용한 작업자로부터 실시간 생체 신호를 수신하고, 외부 시스템에서 작업자의 위험 상태를 공유 및 분석함으로써 작업자의 현재 상태를 진단하고 작업자에게 발생할 수 있는 응급 상황에 효율적으로 대응할 수 있다. 본 논문에서는 사고 현장에서 응급 상황에 대처하기 위해 보호복 착용자의 유해 가스와 산소포화도 위험도를 실시간 모니터링할 수 있고, 착용자의 활동성과 안전성을 보장할 수 있는 웨어러블 산소포화도 측정 플랫폼 기술을 제안하였다. 추후 제안한 시스템의 결과를 통해 확인한 한계점을 극복하고, 움직임 보정 등 개선된 생체 데이터를 플랫폼에 적용한다면 유해 가스 환경뿐만 아니라 응급 환자를 대상으로 하는 병원이나 가정에서도 활용할 수 있을 것이라 기대한다.

• 농촌의학ㆍ지역보건
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• 제48권4호
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• pp.239-250
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• 2023

이 연구는 농업인의 업무상질환에 대한 예방사업을 위한 사전 연구로서 업무상질환 등 농업인들이 인지하고 있는 우선순위를 선정하고, 또한 예방사업 역시 농업인들이 인지하고 있는 주요질환들의 사업 중 효과와 실천가능성을 파악하여 이후 농업인 안전보건사업의 근거자료로 활용하고자 한다. 연구 대상자는 지역에 거주하고 있는 농업인들을 눈덩이 모집 방식으로 선정하였으며 전체 671명을 대상으로 하였다. 우선순위 선정 방식은 BPRS 방법으로 하였으며, 각 업무상질환 중근골격질환, 심혈관 및 호흡기질환 그리고 농약 중독 예방을 위한 세부 사업에 대한 농업인들인 인지하는 효과와 실천가능성을 설문 조사하였다. 업무상질환 중 가장 높은 우선순위는 근골격질환이었으며, 호흡기질환, 농약 중독 등의 순이었으며, 근골격계질환의 세부 사업 중 '농작업편이장비, 보조도구 활용'이 인지하고 있는 효과정도와 실천가능성이 가장 높았다. 농약 중독 5가지 세부 사업 중 효과는 '농약 방제복/장갑 등 보호장비 구비'가 67.4%로 가장 높았으며, 실천가능성 정도는 '농약 사용법 준수'가 64.3%로 가장 높았다. 호흡기질환 예방을 위한 4가지 세부사업 중 효과와 실천 가능성 모두 '분진마스크 또는 방독마스크 착용'이 65.5%로 가장 높았다. 농업인들을 위한 안전보건사업을 수행할 때 근골격질환을 위한 사업을 우선적으로 하여야 할 것이며, 농약중독, 호흡기질환 역시 우선순위를 고려하여야 하며, 농업인들이 인지하고 있는 효과 크기와 실천 가능성을 함께 고려하여 사업 내용을 구성하여야 할 것이다.

• 한국항공우주학회지
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• 제48권10호
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• pp.821-829
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• 2020

항공기 소프트웨어의 건전성 관리시스템은 수행 중에 발생하는 오류를 수리하여 안전성을 제공하고 유지보수 비용을 절감한다. 순서 위배 오류는 개발 단계에서 모두 제거하는 것이 어렵기 때문에 운용 단계에서 자율적으로 수리할 수 있어야 한다. 순서 위배를 자율 수리하기 위한 기존 연구는 각 접근사건의 수행 직전에 접근사건 순서를 비교하여 오류를 진단하기 때문에 접근사건 수에 비례하는 시간 오버헤드를 발생시킨다. 본 논문은 접근사건을 포함하는 함수의 올바른 순서 정보로 오류를 진단하고 해당 함수를 지연시켜 조치하는 기법인 ORS를 제시한다. ORS를 평가하기 위해, 순서 위배 오류를 포함하는 5가지의 합성 프로그램에 기존 연구와 ORS를 적용하여 시간 오버헤드를 측정하였다. 그 결과, 접근 횟수가 약 60번 이상일 때 기존 연구보다 효율적임을 확인하였다.