• Journal of the Society of Naval Architects of Korea
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• v.45 no.6
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• pp.611-619
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• 2008

In most shipyards Floating Dock-gate System is adapted for dry docks. For the safe launching of ships in dry docks, smooth operation of dock-gate must be guaranteed. So it is very important to grasp its behavior in waves for securing the high productivity and the safety of workers. Its seakeeping ability was estimated numerically at the floating conditions and the free roll decay and the seakeeping model tests of dock-gate was carried out with bilge-keels of 3 different widths which have a scale of 1 to 20. More than 20% decrease of roll motion was observed in irregular beam seas by applying a bilge-keel system to the dock-gate that is long and narrow.

• The Journal of the Convergence on Culture Technology
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• v.3 no.1
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• pp.1-8
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• 2017

We are investigated about the state of the working circumstances and infection blocking facility within Metropolitan, Chungcheong and Gyeongsang regions in Korea. The result is as follows. The HAV vaccination rate is 35% and the HBV vaccination rate is 50% among the funeral directors. We expected that the infection risk of funeral directors was very high. Significantly, tuberculosis prevalence rate of funeral director was four times as high as the public. The wear rate of gown, mask, gloves showed relatively high than the others. The wear rate of individual protective equipments has decreased with work experience. The funeral directors have shown that there is difficult to get safe protection from infection. The personal hygiene of funeral directors and the infection blocking equipment should be strengthened institutionally. We are thought to recommend institutional support about infection management, individual protective equipment, vaccination of funeral director and guideline to avoid reversion to previous habitual behavior.

• International Journal of Naval Architecture and Ocean Engineering
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• v.5 no.1
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• pp.161-177
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• 2013

High-speed vessels require good resistance and seakeeping performance for safe operations in rough seas. The resistance and seakeeping performance of high-speed vessels varies significantly depending on their hull forms. In this study, three planing hulls that have almost the same displacement and principal dimension are designed and the hydrodynamic characteristics of those hulls are estimated by high-speed model tests. All model ships are deep-V type planing hulls. The bows of no.2 and no.3 model ships are designed to be advantageous for wave-piercing in rough water. No.2 and no.3 model ships have concave and straight forebody cross-sections, respectively. And length-to-beam ratios of no.2 and no.3 models are larger than that of no.1 model. In calm water tests, running attitude and resistance of model ships are measured at various speeds. And motion tests in regular waves are performed to measure the heave and pitch motion responses of the model ships. The required power of no.1 (VPS) model is smallest, but its vertical motion amplitudes in waves are the largest. No.2 (VWC) model shows the smallest motion amplitudes in waves, but needs the greatest power at high speed. The resistance and seakeeping performance of no.3 (VWS) model ship are the middle of three model ships, respectively. And in regular waves, no.1 model ship experiences 'fly over' phenomena around its resonant frequency. Vertical accelerations at specific locations such as F.P., center of gravity of model ships are measured at their resonant frequency. It is necessary to measure accelerations by accelerometers or other devices in model tests for the accurate prediction of vertical accelerations in real ships.

• Journal of Pharmacopuncture
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• v.19 no.3
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• pp.253-258
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• 2016

Objectives: The goals of this research were to evaluate acute (single-dose) and sub-acute (repeated-dose) toxicity profiles of methanolic extract of Pistacia integerrima J. L. Stewart ex Brandis (PI) for Wistar rats and to assess the safety profile of PI by observing physiological changes, mortality, changes in body weight, the histopathology of body organs, the hematology and the biochemistry of the animals. Methods: The toxicity profile of PI was evaluated using Wistar rats of both sexes. Animals were divided into four groups: Group 1; control group (normal saline), Group 2; PI-1 (250 mg/kg), Group 3; PI-2 (500 mg/kg), Group 4; PL-3 (1,000 mg/kg). An acute-toxicity study in which animals received a single dose of PI extract (2,000 mg/kg) and were then observed for 14 days for changes in skin, fur, eye color, mucous membrane secretions and excretions, gait, posture, and tonic or clonic movements was performed according to guideline 425 of the Organization of Economic and Corporation Development (OECD). In the repeated-dose toxicity study (OECD - 407) animals received a daily dose of PI extract for 28 days (4 weeks). The parameters observed in this study include body weight, hematology and biochemistry of the animals. Results: In the acute toxicity study, no mortalities or changes in behavior were noted in the animals. The repeated-dose toxicity study was also devoid of any toxicity in the animals during the 28 days of testing with PI extract. The extract did not alter- the body weight, hematology or biochemistry of the animals. The methanolic extract of PI was to be found safe to the no-observed-adverse-effect-level (NOAEL) for the single-dose and repeated-dose toxicity tests in rats. Conclusion: The methanolic extract of PI was devoid of toxicity; hence, it can be used for various ayurvedic preparations and treatments of diseases.

• Korean Journal of Clinical Pharmacy
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• v.23 no.3
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• pp.197-205
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• 2013

Background: Many factors including drugs, dietary supplements, and food intake can affect the development and organ formation of fetuses. Because of this, subject tends to avoid consuming things like coffee, alcohol, or cigarettes due to the risks they pose during pregnancy. Therefore, analysis of drugs and favorite food consumption is needed and important to ensure safe health management for subject. Purpose: This study was conducted domestically to analyze these factors in South Korea. Method: The survey was conducted from pregnancy-related online communities for six days and the survey results were received via email for analysis. Result: A total of 127 subjects answered the questionnaire via email; the characteristics of subjects are widely varied in their ages, education levels, job statuses, and residences. The questionnaire included the intake of dietary supplements during pregnancy including vitamins and the result showed that the subjects took 2.23 different kinds of supplements on average. In order of highest frequency, 101 subjects took multivitamins; 79 subjects took an iron supplement; 30 subjects took analgesics; 20 subjects took prescribed antipyretic and medication for upper respiratory diseases; 12 subjects took antibiotics; 7 subjects took antiemetics. Their compliances were different in each medication categories. Only 8% of subjects answered that they had asked a pharmacist for medication information during pregnancy. In addition, 78% of subjects answered that they never counseled with anyone about pregnancy related medication use. Conclusion: In conclusion, many subjects took medication including dietary supplements. The role of pharmacists should be actively developed to improve subject care such as education about subject's medication uses and their food consumption behavior.

• Journal of the Korean Geosynthetics Society
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• v.5 no.4
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• pp.35-42
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• 2006

This paper describes a field experience on geogrid-reinforced soil walls rising up to 29.5m in height. Since experiences of design and construction on very high-raised geogrid reinforced soil wall were limited, thorough design and construction management was performed for safe construction of the wall. Regarding design of the wall, both internal and external stabilities were examined based on the design guideline specified by FHWA and overall slope stability analyses were performed by using Bishop simplified method. Moreover, a series of instrumentations were performed. The results of instrumentation for two tiered reinforced soil wall showed that not only the deformations of both the wall face and the reinforcement but also the horizontal earth pressures acting on the wall facing were very small. These results indicate that the reinforced soil wall technology can be applied successfully for high-raised tiered wall more than 20m heights and FHWA design guideline is very conservative for that large wall.

• Journal of the Korean Society of Safety
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• v.35 no.5
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• pp.121-127
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• 2020

Since the Fukushima nuclear accident in 2011, the public were concerned about the safety of Nuclear Power Plants (NPPs) in extreme natural disaster situations, such as earthquakes, flooding, heavy rain and tsunami, have been increasing around the world. Accordingly, the Stress Test was conducted in Europe, Japan, Russia, and other countries by reassessing the safety and response capabilities of NPPs in extreme natural disaster situations that exceed the design basis. The extreme natural disaster can put the NPPs in beyond-design-basis conditions such as the loss of the power system and the ultimate heat sink. The behaviors and capabilities of NPPs with losing their essential safety functions should be measured to find and supplement weak areas in hardware, procedures and coping strategies. The Loss of Ultimate Heat Sink (LUHS) accident assumes impairment of the essential service water system accompanying the failure of the component cooling water system. In such conditions, residual heat removal and cooling of safety-relevant components are not possible for a long period of time. It is therefore very important to establish coping strategies considering all available equipment to mitigate the consequence of the LUHS accident and keep the NPPs safe. In this study, thermal hydraulic behavior of the LUHS event was analyzed using RELAP5/Mod3.3 code. We also performed the sensitivity analysis to identify the effects of the operator recovery actions and operation strategy for charging pumps on the results of the LUHS accident.

• Journal of Korean Society on Water Environment
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• v.22 no.3
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• pp.475-481
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• 2006

The major problem in closing water like lakes and ponds in Korea is that because they are exposed to surrounding, so easily polluted. The pollution in closing water can be caused by not only artificial factor like sewage but also natural factor like elution from sediment. For insurance of safe and satisfied water source, lots of studies and projects are now going on. In this study, we examined the behavior and effect of microbubble ($3{\sim}10{\mu}m$) produced by device called O.S.D (Oxygen Solubillization Device) in small size pond. The value of oxygen transfer coefficient ($K_La$) was 0.68/min independently of air flow rate, 6.5 times higher than commercial aeration stone and the variation of nitrogen concentration was $0.008NO_3/O_2$, DO concentration was potentially saturated for 24 hr. From the results of pilot plant, SOD of experiment (O.S.D) and control were $12.18gO_2{\cdot}m^{-2}{\cdot}d^{-1}$ and $47.95gO_2{\cdot}m^{-2}{\cdot}d^{-1}$ respectively. In conclusion, because O.S.D has extraordinary physico-chemical characteristics, it can contribute to improvement of both the waterbody and the sediment environment.

• Parasites, Hosts and Diseases
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• v.57 no.5
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• pp.499-504
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• 2019

Head-lice infestation, pediculosis capitis, remains a public-health burden in many countries. The widely used first-line pediculicides and alternative treatments are often too costly for use in poor socio-economic settings. Ivermectin has been considered an alternate treatment for field practice. This study was composed of 2 parts, a cross-sectional survey and an intervention study. The main objectives were to determine the prevalence and potential factors associated with head-lice infestation, and to evaluate the effectiveness and safety of oral ivermectin administration. A community-based cross-sectional survey was conducted among 890 villagers in rural areas along Thai-Myanmar border. Females with infestations were eligible for the intervention study, and 181 participated in the intervention study. A post-treatment survey was conducted to assess acceptance of ivermectin as a treatment choice. Data analysis used descriptive statistics and a generalized-estimation-equation model adjusted for cluster effect. The study revealed the prevalence of head-lice infestation was 50% among females and only 3% among males. Age stratification showed a high prevalence among females aged <20 years, and among 50% of female school-children. The prevalence was persistent among those with a history of infestation. The major risk factors were residing in a setting with other infected cases, and sharing a hair comb. The study also confirmed that ivermectin was safe and effective for field-based practice. It was considered a preferable treatment option. In conclusion, behavior-change communication should be implemented to reduce the observed high prevalence of head-lice infestation. Ivermectin may be an alternative choice for head-lice treatment, especially in remote areas.

• Journal of Pharmacopuncture
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• v.21 no.4
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• pp.277-283
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• 2018

Objectives: Ethanol withdrawal following its chronic use is a serious outcome and challenging to treatment. The chronic use of ethanol induces a progressive neuroplasticity in different reigns of brain. In this study we evaluated the effects of aqueous extract of Crocus sativus L. (saffron) and its active compound, crocin, on the withdrawal behavior induced after repeated administration of ethanol, in two regimens of prophylactic (administration of drugs concomitant with the induction of dependence) and treatment (administration of drugs during the period of ethanol withdrawal) in mice which received ethanol. Methods: Ethanol dependence was induced by oral administration of 10% v/v ethanol (2 g/kg) for 7 days. The aqueous extracts of saffron (40, 80 and 160) and crocin (10, 20 and 40 mg/kg) were administered to mice in two regimens of prophylactic (along with ethanol) and treatment (during withdrawal period). Diazepam (1 mg/kg) was used as a positive control. Six hours after discontinuation of the ethanol, seizure was evaluated by the sub-convulsive dose of pentyleneltetrazole (PTZ) (30 mg/kg). The open field test and Rota rod test were used for evaluation of locomotor activity and motor incoordination, respectively. Results: Both extracts and crocin increased the number of crossed lined in the open field test. PTZ kindling seizure was inhibited in animals received extract (80 and 160 mg/kg) in both regimens. Motor incoordination was only improved following administration of crocin. Conclusion: The aqueous extract of saffron and crocin can be considered as safe agents and reliable alternative to diazepam in management of ethanol withdrawal syndrome.