• Electronics and Telecommunications Trends
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• v.36 no.1
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• pp.81-88
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• 2021

Post COVID-19, the medical legacy system will be transformed for utilizing medical resources efficiently, minimizing medical service imbalance, activating remote medical care, and strengthening private-public medical cooperation. This can be realized by achieving an entire medical paradigm shift and not simply via the application of advanced technologies such as AI. We propose a medical system configuration named "Medical AI Hub" that can realize the shift of the existing paradigm. The development stage of this configuration is categorized into "AI Cooperation Hospital," "AI Base Hospital," and "AI Hub Hospital." In the "AI Hub Hospital" stage, the medical intelligence in charge of individual patients cooperates and communicates autonomously with various medical intelligences, thereby achieving synchronous evolution. Thus, this medical intelligence supports doctors in optimally treating patients. The core technologies required during configuration development and their current R&D trends are described in this paper. The realization of the central configuration of medical AI through the development of these core technologies will induce a paradigm shift in the new medical system by innovating all medical fields with influences at the individual, society, industry, and public levels and by making the existing medical system more efficient and intelligent.

• Plant Biotechnology Reports
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• v.4 no.2
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• pp.129-138
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• 2010

An efficient transformation system for high-throughput functional genomic studies of kiwifruit has been developed to overcome the problem of necrosis in Actinidia arguta explants. The system uses Agrobacterium tumefaciens strain EHA105 harbouring the binary vector pART27-10 to inoculate leaf strips. The vector contains neomycin phosphotransferase (nptII) and ${\beta}$-glucuronidase (GUS) (uidA) genes. A range of light intensities and different strengths of Murashige and Skoog (MS) basal salt media was used to overcome the problem of browning and/or necrosis of explants and calli. Callus browning was significantly reduced, resulting in regenerated adventitious shoots when the MS basal salt concentration in the culture medium was reduced to half-strength at low light intensity ($3.4\;{\mu}mol\;m^{-2}\;s^{-1}$) conditions. Inoculated leaf strips produced putative transformed shoots of Actinidia arguta on half-MS basal salt medium supplemented with 3.0 $mg\;l^{-1}$ zeatin, 0.5 $mg\;l^{-1}$ 6-benzyladenine, 0.05 $mg\;l^{-1}$ naphthalene acetic acid, 150 $mg\;l^{-1}$ kanamycin and 300 $mg\;l^{-1}$ $Timentin^{(R)}$. All regenerated plantlets were deemed putativ transgenic by histochemical GUS assay and polymerase chain-reaction analysis.

• Journal of Information Display
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• v.3 no.4
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• pp.19-22
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• 2002

In this paper, we introduce an efficient three-dimensional magnetic field mapping system for a Deflection Yoke (DY) in Cathode-Ray Tube (CRT). A three-axis Hall probe mounted in a small cylindrical bar and three-stepping motors placed in a non-magnetic frame were utilized for the mapping. Prior to the mapping starts, the inner contour of DY was measured by a laser sensor to make a look-up table for inner shape of DY. Three-axis magnetic fields are then digitized by a three-dimensional Hall probe. The results of the mapping can be transformed into various output formats such as multi pole harmonics of magnetic fields. Field shape in one, two and three- dimensional spaces can also be displayed. In this paper, we present the features of this mapping device and some analysis results.

• Earthquakes and Structures
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• v.9 no.1
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• pp.173-194
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• 2015

Site response analysis is an important topic in earthquake engineering. A time-domain numerical method called as one-dimensional (1D) finite element artificial boundary method is proposed to simulate the homogeneous plane elastic wave propagation in a layered half space subjected to the obliquely incident plane body wave. In this method, an exact artificial boundary condition combining the absorbing boundary condition with the inputting boundary condition is developed to model the wave absorption and input effects of the truncated half space under layer system. The spatially two-dimensional (2D) problem consisting of the layer system with the artificial boundary condition is transformed equivalently into a 1D one along the vertical direction according to Snell's law. The resulting 1D problem is solved by the finite element method with a new explicit time integration algorithm. The 1D finite element artificial boundary method is verified by analyzing two engineering sites in time domain and by comparing with the frequency-domain transfer matrix method with fast Fourier transform.

• Journal of Biosystems Engineering
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• v.33 no.4
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• pp.248-252
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• 2008

An experiment was conducted in order to investigate gasification characteristics of rice husks in a fixed bed, which was a pre-step to design a continuous gasification system. Two air supply levels for gasification were chosen and their effects on the producer gas amount and producer gas composition were discussed. The main components of the producer gas were CO, $CO_2$, $O_2$, $H_2$ and THC (Total HydroCarbon). As airflow rate decreased, more producer gas was produced. The peak amount of CO, $H_2$ and THC were 28%, 7.5% and 0.68% in volume when constant airflow rate of $3.36\;m^3/s$ was used in the batch operation. About 4.5 kg of ash (9%) and condensed water including tars of 6 kg (11%) were produced from 50 kg rice husks in the gasification. Excluding the byproducts, all rice husks seemed to be transformed into producer gas. This gasification study was conducted prior to developing a continuous gasification system for biomass including agricultural byproducts.

• BMB Reports
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• v.31 no.1
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• pp.77-82
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• 1998

To purify the geranylgeranyl protein transferase type I (GGPT-I) efficiently, a gene expression system using the pGEX-4T-1 vector was constructed. The cal1 gene, encoding the ${\beta}$ subunit of GGPT-I, was subcloned into the pGEX-4T-1 vector and co-transformed into E. coli cells harboring the ram2 gene, the ${\alpha}$ subunit gene of GGPT-I. GGPT-I was highly expressed as a fusion protein with glutathione S-transferase (GST) in E. coli, purified to homogeneity by glutathione-agarose affinity chromatography, and the GST moiety was excised by thrombin treatment. The purified yeast GGPT-I showed a dose-dependent increase in the transferase activity, and its apparent $K_m$ value for an undecapeptide fused with GST (GST-PEP) was $0.66\;{\mu}M$ and the apparent value for geranylgeranyl pyrophosphate (GGPP) was $0.071\;{\mu}M$.

• Korean Journal of Veterinary Research
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• v.57 no.1
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• pp.9-15
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• 2017

To construct a novel vaccine candidate against bovine enterotoxigenic Escherichia coli (ETEC), FanC, the major subunit of K99 fimbriae adhesion, was inserted into secretion plasmid pYA3560 containing a ${\beta}-lactamase$ secretion system. This was then transformed into ${\Delta}asd$ ${\Delta}crp$ Salmonella (S.) Typhimurium and designated as JOL950. Secretion of recombinant fanC fimbrial antigens was confirmed by immunoblot analysis. Groups of mice were inoculated with single or double doses of JOL950. Another group was used as a negative control. Compared to control mice, all immunized mice had significantly higher levels (p < 0.05) of serum immunoglobulin (Ig)G, and secretory IgA against FanC. The IgG2a and IgG1 titer assays revealed that immunization highly induced IgG2a compared to that of IgG1, indicating that T helper-1- related cell-mediated immune responses may be elicited by JOL950. The results show that both systemic and mucosal immunities against selected fimbrial antigens of bovine ETEC expressed by a live attenuated S. Typhimurium strain are prominently produced in mice immunized with JOL950 via an oral route.

• Journal of the Korean Institute of Intelligent Systems
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• v.11 no.8
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• pp.754-759
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• 2001

In this paper, we propose a TSK(Takagi-Sugeno-Kang)-type fuzzy classifier using PCA(Principal Component Analysis), FCM(Fuzzy c-Means) clustering, ANFIS(Adaptive Neuro-Fuzzy Inference System) and hybrid GA(Genetic Algorithm). First, input data is transformed to reduce correlation among the data components by PCA. FCM clustering is applied to obtain a initial TSK-type fuzzy classifier. Parameter identification is performed by AGA(Adaptive GA) and RLSE(Recursive Least Square Estimate). Finally, we applied the proposed method to Iris data classificationl problems and obtained a better performance than previous works.

• Proceedings of the KSME Conference
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• 2004.04a
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• pp.1011-1016
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• 2004

All the loads in the real world are dynamic loads and it is well known that structural optimization under dynamic loads is very difficult. Thus the dynamic loads are often transformed to the static loads using dynamic factors. However, due to the difference of load characters, there can be considerable differences between the results from static and dynamic analyses. When the natural frequency of a structure is high, the dynamic analysis result is similar to that of static analysis due to the small inertia effect on the behavior of the structure. However, if the natural frequency is low, the inertia effect should not be ignored. Then, the behavior of the dynamic system is different from that of the static system. The difference of the two cases can be explained from the relationship between the homogeneous and the particular solutions of the differential equation that governs the behavior of the structure. Through various examples, the difference between the dynamic analysis and the static analysis are shown. Also the optimization results considering dynamic loads are compared with static loads.

• Microbiology and Biotechnology Letters
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• v.13 no.4
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• pp.345-348
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• 1985

Recombinant chimeric plasmid constructed with Xba I digested pUBl10 and -pE194 was transformed by polyethylene glycol induced protoplast transformation system into Bacillus subtilis BR 151 on the mannitol regeneration media, and two genes of antibiotics resistance were expressed simultaneously in the transfromant. Transformation frequency of the recombinant plasmid was 6.5 $\times$ 10$^{-5}$ on the mannitol regeneration agar plate containing neomycin and erythromycin. The replication of recombinant plasmid in the recipient cells was confirmed by the alkaline extraction method and agarose gel electrophoresis.