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Effects of Propolis oral administration according to mixture with Hovenia dulcis Thunb. and Artemisia capillaris Thunb. on D-galactosamine-induced liver injury in rats (지기자(枳期子) 및 인진호(茵蔯蒿) 배합(配合) Propolis의 구강투여(口腔投與)가 D-Galactosamine으로 유발(誘發)된 간손상(肝損傷)에 미치는 영향(影響))

  • Youn, Dae-Hwan;Jeong, Jong-Gil;Na, Chang-Su
    • The Korea Journal of Herbology
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    • v.21 no.3
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    • pp.7-19
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    • 2006
  • Objectives : Propolis and Hovenia dulcis Thunb. has been used as treatment of diseases in the Korean medicine. In this study, we investigated that the hepatoprotective effects of Propolis oral administration according to mixture with Hovenia dulcis Thunb. on ${\gamma}-GTP$, GOT, GPT, Total bilirubin, LDH, ALP, Total cholesterol, Triglyceride, SOD, activity of catalase and Glutathione Peroxidase in galactosamine (GalN)-induced liver in rats. Methods : The animals were divided into 5 groups. Control, the liver injury-induced and not treated group. Pro1, liver injury and administrated propolis. Pro2, liver injury and administrated propolis capsule. Pro3, liver injury and administrated mixture of propolis capsule with Hovenia dulcis Thunb. Pro4, liver injury and administrated mixture of Propolis capsule with Hovenia dulcis Thunb. and Artemisia capillaris Thunb.. Animals were treated by Oral administration of Propolis, Hovenia dulcis Thunb., and Artemisia capillaris Thunb. mixture ltime 2 days for 14 days. Results : The Pro1 group was significantly increased on ${\gamma}-GTP$ and activity of Glutathione peroxidase but decreased on GOT in serum as compared with the control group. The Pro2 group was significantly increased on WBC, RBC, Hct, HGB in serum and activity of CuZnSOD as compared with the control group. The Pro 3 group was decreased on Total bilirubin, increased on LDH, WBC, RBC, Hct and HGB in serum as compared with the control group. The Pro 4 group was decreased on GOT in serum as compared with the control group. Conclusion : By evaluating the liver function and lipid metabolism, Pro3 had a hepatoprotective effect on the prevention of hepatotoxity.

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A Study on Sinusitis in Pediatric Patients : the Analysis of Age and the Classification of Korean Medical Clinical Type (한방병원에 내원한 부비동염 환아의 연령 분석 및 임상 유형 분류)

  • Lee, Sun Jung;Kang, Kyung Ha;Park, Eun Jeong
    • The Journal of Pediatrics of Korean Medicine
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    • v.30 no.1
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    • pp.9-21
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    • 2016
  • Objectives The purpose of this study is to analyze sinusitis patients who visited the department of pediatrics, OO Korean medicine hospital by using their age and to classify the clinical type by Korean medical theory. Methods The study was conducted based on 178 cases that consisted of sinusitis patients (from 1 to 15 years old) who visited OO Korean medicine hospital from March 2014 to March 2015. We analyzed the age of patients and classified them by the clinical type by reviewing patient's charts. After that, we compared the results with the results of previous studies. Results and Conclusions 178 Patients were studied. 2-years-age group was 19.7% of the study group which was higher than that of previous studies. The Lung-Kidney Yin Deficiency (肺腎陰虛) group was 33.1%, Wind-Heat (風熱) group was 29.8% and the Wind-Cold (風寒) group 18.5%, Spleen-Lung Qi Deficiency (脾肺氣虛) group was 15.7% and the Heart-Spleen Qi Deficiency (心脾氣虛) group was 2.8% of the study group. Children are full of Yang but lack of Yin (陽常有餘陰常不足) so they easily transform into heat and fire (化熱化火). The patients who had sinusitis were most likely to suffer from the common cold for more than a week, once a month. 45.1% of the people from the study group was suffered from common cold more than a week, and 43.8% of the people got common cold once a months. About 21.6 % and 18.3% of the people got common cold twice a month and once every 2 months, respectively. The remaining 15.7% got cold during the season changes.

A analysis on the Patient's awareness of periodontal diseases (치과에 내원하는 환자들의 치주질환 인식도에 관한 분석)

  • Kim, Young-Im;Heo, Hee-Young
    • Journal of Korean society of Dental Hygiene
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    • v.8 no.3
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    • pp.107-114
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    • 2008
  • The purpose of this study was to examine the awareness of adult patients visiting dental clinics about periodontal diseases. The subjects in this study were 204 patients who paid a visit to five dental clinics and a dental hospital in the region of Jeonju. After a survey was conducted, the results were obtained as follows: 1. With regard to toothbrushing method, the most of the male patients(43.8%) brushed their teeth by rolling the toothbrushes up and down, and the most of the female patients(46.1%) did that both up and down and right and left. As to the influence of smoking, the largest number of the smokers(50.0%) and nonsmokers(40.4%) brushed their teeth both up and down and right and left. statistically significant differences were shown by gender and smoking(p<0.05). 2. As for knowledge acquisition route on periodontal diseases by gender, there was no way for the men(38.2%) to get the information, and the largest number of the women (43.4%) acquired the information through the internet. With respect to smoking, the largest numbers of the smokers(38.2%) and nonsmokers(37.5%) got the information by the internet, and statistically significant differences were found (p<0.05). 3. Concerning treatment method of periodontal diseases provided by the dental clinic, the largest number of the men(33.7%) got their teeth scaled, and the greatest group of the women(29.6%) had their gums treated. The treatment method made statistically significant differences by gender (p<0.05). Regarding smoking, the largest group of the smokers(32.4%) had their teeth scaled, and the largest number of the nonsmokers(28.7%) got their gums treated. significant differences were made statistically by smoking (p<0.05). 4. As to instruction on the prevention of periodontal diseases, the largest group(63.2%) intended to take that. The second (23.0%) was eager to do it, and the third(13.8%) was unwilling to do it.

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Protective effects of Jucha-whan on liver injury of guinea pigs induced by $CCl_4$ and d-galactosamine (주차환(舟車丸)이 $CCl_4$ 및 d-galactosamine으로 유발된 흰쥐의 간손상(肝損傷)에 미치는 영향)

  • Kang Jae-Chun;Choi Eun-Ju
    • The Journal of Internal Korean Medicine
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    • v.24 no.1
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    • pp.55-67
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    • 2003
  • Objective : In order to investigate the curative effect of Jucha-whan on the protective liver of guinea pigs induced by $CCl_4$ and d-galactosamine, serum transaminase(GOT, GPT), lactic dehydrogenase(LDH), alkaline phosphatase(ALP), glutathione S-transferase(GST), superoxide dismutase(SOD) were used to measure enzyme activities and lipid peroxide level. Method : The subject animals were divided into 5 groups; a control group(untreated), a subject group(administered with 0.9% Saline solution), a sample I (500mg/kg administered), sample II group (1000mg/kg administered), positive control group(administered with 200mg/kg silymarine). Result : The inhibitory effects on the serum GOT, LDH, ALP, SOD and Lipid peroxide level activities in protective liver of mice induced by $CCl_4$ were noted both in the sample I group and sample II. The inhibitory effects on the serum GPT activities in protective liver of guinea pigs induced by $CCl_4$ were noted in sample II group, but it was not noted in the sample I. The inhibitory effects on the GST activities in protective liver of guinea pigs induced by $CCl_4$ were not noted in both sample I and sample group II. The inhibitory effects on the serum GOT, GPT activities in protective liver of guinea pigs induced by d-galactosamine were noted in both sample I and sample II, but it was not recognizable statistically. The inhibitory effects on the serum LDH activities in protective liver of guinea pigs induced by d-galactosamine were noted in sample II, but it was not noted in sample I group. Conclusion : According to the above results, it is considered that Jucha-whan has treatment effects on liver injury in guinea pigs induced by $CCl_4$ and d-galactosamine. So it is required to study about the actions of mutual relation of medicines and patho-mechanism through experiment.

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A study on knowledge and attitude of dental hygienics students in AIDS (치위생과 학생들의 에이즈에 관한 지식과 태도 조사 연구)

  • Sung, Bo-Kyun
    • Journal of Korean society of Dental Hygiene
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    • v.7 no.3
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    • pp.259-271
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    • 2007
  • AIDS is increasing by geometric progression in the world with more seriousness and HIV/AIDS is still spreading. Thus, the study enforced a self-administered survey with 526 dental hygiennics students to carry out an upright recognition and education on AIDS by grasping knowledge and attitude of dental hygienics students who will work at dental hospitals or clinics after graduating in AIDS. As the result, the study got the following conclusion. 1. 51.1% of the students got knowledge on AIDS and the majority out of them got its knowledge through school(35.2%) or mass media(10.8%). 2. The average score of dental hygienics students' knowledge in AIDS was 87.67: The first-grade students(86.00), the second-grade students(88.88) and the third-grade students(88.37) (p=0.000). 3. They had an accurate recognition about AIDS' causes, its infection ways and interceptive methods of its infection way in knowledge of AIDS(p=0.000). 4. In their attitudes for AIDS, the average score was $57.43{\pm}$: The first-grade students(56.19), the second-grade students(57.70) and the third-grade students(58.70)(p=0.001). 5. In their attitudes for AIDS, the students($4.09{\pm}0.82$ scores) responded that they would prepare for AIDS' infection of their families(p=0.004) while, on the other hand, the students($4.06{\pm}0.82$ scores) responded that they wanted to avoid PWA's dental treatment(p=0.001). Therefore, it is judged that vocational education as a specialized worker as well as AIDS education should be realized since it was appeared that they had not enough thought as a mature professional worker. 6. Dental hygienics students who would work at dental hospitals or clinics after graduating were in the environment infected in all diseases and so most of the students($4.23{\pm}0.74$) responded that AIDS education should be included in curriculum.

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Quality of Life Using WHOQOL-Bref in Taegu (WHOQOL-Bref를 이용한 대구시민의 삶의 질)

  • 이종렬;박천만
    • Health Policy and Management
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    • v.10 no.3
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    • pp.129-154
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    • 2000
  • This study aims at providing the basic data necessary for developing a model of and the policies for the improved quality of life of the adult population by measuring and analyzing factors affecting the quality of life based on a WHOQOL-Bref survey of 1,200 persons above the age of 20 residing in Taegu Metropolitan City area. 1. The factors affecting their quality of life were measured as follows: The physical conditions got the highest point of 3.31 while the psychological conditions got 3.20 and the environmental conditions got the lowest point of 3.09. The overall quality of life was rated to be at 3.11 2. General conditions affecting the quality of life, such as the economic conditions, health conditions and stress all turned out to be variables having significant differences(p〈0.01) in all the factors affecting the quality of life. 3. Through the analysis, we also found out the positive correlation exists among all the factors determining the quality of life(p〈0.01), while the psychological factor turning out to have the highest correlation value(r=0.640) with the overall quality of life. 4. To find out the factors affecting all the aspects of quality of life, we also conducted a multiple regression analysis employing the general characteristics as an independent variable. The health, economic and stress conditions all turned out to be significant in all aspects(p〈0.01). Summarizing the above analysis, the quality of life has a high correlation with the psychological, physical and environmental conditions. It has also turned out that the health, economic and stress conditions have the greatest influence on the quality of life. Therefore, it is believed to be necessary that a comprehensive program be developed to promote the public health and to formulate a model for improvement of the people's quality of life that can enhance their physical, psychological and social health conditions.

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A study on motivation for major choice and major adaptation among some dental hygiene students (일부 치위생과 학생의 학과선택 동기 및 적응도)

  • Jang, Gye-Won;Lee, Ji-Young;Jeong, Mi-Kyoung
    • Journal of Korean society of Dental Hygiene
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    • v.13 no.2
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    • pp.335-342
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    • 2013
  • Objectives : The purpose of this study was to examine the satisfaction level of students with a job tour program and their major and their adaptation to their major in an effort to provide some information on student guidance and the improvement of dental hygiene education. Methods : The subjects in this study were 269 freshmen to find out their views of job tour and the relationship of their general characteristics and motivation of major choice to satisfaction level with their major and adaptation to the department, t-test and one-way ANOVA were carried out. And correlation analysis was made to look for connections among major satisfaction, major adaptation and satisfaction with job tour. Results : 1. As for the choice of major, the biggest group of 128 students (47.6%) made a decision on their own. 2. In regard to satisfaction level with their major, the freshmen got $3.55{\pm}0.67$, and the sophomores got $3.36{\pm}0.66$. There was a significant difference according to academic year(p<0.05). 3. Concerning the links between motivation for major choice and major satisfaction, the students who chose their major in consideration of their own aptitude or personality got the highest marks of $3.96{\pm}0.64$(p<0.05). 4. As to satisfaction level with the job tour program, they were most satisfied with field trip($4.03{\pm}0.74$). 5. Regarding the correlation among major satisfaction, major adaptation and satisfaction with the job tour program, there was a significant correlation among all the variables(p<0.01). Conclusions : The students who gave priority to their own aptitude and personality in choosing their major were more satisfied with their major and were better adapted to that. Therefore it's required to consider how to boost the satisfaction level of students with their major and their adaptation to that.

Effects of Water Extracts of Camelia sinensis L on Blood Alcohol Concentration and Activities of Acute Alcohol Metabolic Enzymes in ICR Mouse (보이차(Camelia sinensis L) 추출물이 ICR Mouse의 급성 알코올 대사에 미치는 효과)

  • Park Su-Hyun;Yoon Hea-Kyung;Koo Sung-Ja
    • Journal of the East Asian Society of Dietary Life
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    • v.14 no.6
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    • pp.634-639
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    • 2004
  • An eight-week-old male ICR mouse, which was induced with acute alcohol and sub-acute alcohol poisoning condition, was administered with bohee tea(Camelia sinensis L) extract. After oral administration of bohee tea and inducement of acute alcohol poisoning condition, the mouses blood alcohol concentration became as low as that of the normal control group. Its decrease rate was 87.26%, in comparison with that of the positive control group. Moreover, its blood GOT activity decreased with a rate of 93.1 % until it reached the normal level, as opposed to that of the positive control group. In addition, the GOT activity, despite rising after the alcohol intake, decreased(p<0.05) significantly after administration of each sample and reached the normal level. The bohee tea group experienced a significant decrease in the GOT activity, compared with the A1codex group and the Drink group. The GPT activity of the Alcodex group decreased by 11 % compared with that of the positive control group. The CTP activity of the bohee tea group decreased by 8.2%, while that of the Drink group decreased by 6.5%(P<0.05). However, there were no significant differences between the results in the control group and those of the test group. The bohee tea group's hepatic ADH activity increased by 22.7% compared with that of the positive control group. On the other hand, the hepatic ADH activity of the Drink group increased by 33.6% while that of the A1codex group increased by 20.4%. On the contrary, the bohee tea extract, the hepatic ALDH did not manifest any significant difference as compared with the normal control group. However, its decrease rate was about 16.67% as compared with that of the positive control group. The Drink group, meanwhile, obtained a decrease rate of about 21.59%.

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A RETROSPECTIVE STUDY ON THE CLINICAL MANEFESTATIONS, ETIOLOGIC FACTORS OR SURGICAL CORRECTION METHODS OF THE MAXILLOFACIAL DEFORMITY PATIENTS (악안면 기형 환자들의 발현 양상, 원인 요소 및 외과적 교정 방법에 관한 역학적연구)

  • Hyeon, Chung-Hwan;Yim, Chang-Joon
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.19 no.3
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    • pp.233-242
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    • 1997
  • Recently the goal of orthognathic surgery has been focused on esthetic improvement of the patients. Also early corrective surgery was favorable selected by most of the oral and maxillofacial surgeons. We should consider the etiologic factor of the patient's dentofacial deformities when treatment is planned, because this is the major factor in estimating the predictability or stability of result. The more researches were carried on the etiologic factors of the dentofacical deformities, The more possibility of the early surgical correction will be increased. The authors analyzed about etiologic factors and epidemiologic studies of the forth patients who had received the orthognathic surgery. The analyzed results were as follows: 1. The predilection ration between male and female was 17:23, and 32 patients (80%) of 40 patients were aged twenties. 2. 26patients(65%) complained estetic problems as well as functional problems. 10 patients(25%) complained only esthetic problems, and 4 of 40 patients complained only functional problems. 3. Mandibular prognathism was found to be done most frequently(25, 39%). Facial asymmetry (13, 20%) and angle hypertrophy were found to be next in sequence. 4. Sagittal split ramus ostetomy was done most frequently(27, 35%). Lefort I osteotomy(13, 17%), angle reduction (12,16%), and genioplasty(11, 15%) were done also. 5. The number of the cases due to nonspecific etiologic factor was 22(55%), that of cases due to inhertied tendency was 12(30%), that of cases due to congenital anomaly was 3(7.5%), and that of cases due to trauma was 3(7.5%). 6. The number of patients who got only maxilliary surgery was 2(5%), that of patients who got only mandibular surgery was 23(57.5%), and that of patients who got simultaneous two jaw surgery was 15(37.5%).

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A Study on Usability of Mugwort and a Clinical Comparison between a Hot Pack to use in Hospital and a Hot Pack to Add Mugwort (병원에서 사용되는 Hot pack과 일회용 쑥 Pack을 첨가해 사용한 Hot pack과의 임상적인 비교 및 쑥의 사용 가능성에 대한 조사 연구)

  • Yu, Chang-Sun
    • Journal of Korean Physical Therapy Science
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    • v.4 no.1
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    • pp.315-327
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    • 1997
  • The purpose of this thesis is to investigate the application of a medical cure with a mixture of the merit of a hydrotherapy, as a kind of a physical therapy, and the remedy efficacy of mugwort, which uses in a chinese medical treatment in order to remove an unpleasant smell of HOT Pack and its tube to use in hospital. The usability of mugwort and the degree of its preference was obtained through question naires sent to 120 students including 50 students of the department of physical therapy. And the feeling, at the moment a HOT Pack Tube was opened, was investigated through 74-physical therapists. This research is to investigate the effect of the remedy to add a mugwort-pack in a HOT Pack tube using already in hospital. The results of this study are as following : The efficacy of a mugwort-pack to get rid of an unpleasant smell got better than that of a HOT Pack and its tube. As most of physical therapy laboratory lies to a basement of a hospital, the efficacy to remove a particular offensive smell of a basement got better than that of a HOT Pack using in a common hospital. Also, the degree of patients' preference on a HOT Pack to add with mugwort got to be higher and increased gradually. I can't see the definite difference of a medical remedy, but, I suppose that the visible feeling was of much help for the effect of patients's remedy.

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