• Bulletin of the Korean Chemical Society
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• v.27 no.8
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• pp.1231-1234
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• 2006

• Archives of Pharmacal Research
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• v.6 no.1
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• pp.29-33
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• 1983

From the roots of Pandia siamensis, D-mannitol, a mixture of .betha.-sitosterol and campesterol, oleanolic acid acetate, oleanolic acid-3-.alpha.-L-arabino side and mesembryanthemoidigenic acid as a sapogenin were isolated and characterized.

• Natural Product Sciences
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• v.26 no.2
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• pp.144-150
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• 2020

Phytochemical investigation of leaves, barks and roots of Nauclea vanderguchtii led to the isolation of sixteen compounds, which includes one citric acid derivative (2), one alkaloid (16), one peptide derivative (3), and twelve triterpenes (1, 4 - 13). These compounds were identified as rotundanonic acid (1), 2-hydroxy-1,2,3-propanetricarboxylic acid 2-methyl ester (2), asperphenamate (3), lupeol (4), stigmasterol (5), betulin (6), betulenic acid (7), stigmasterol 3-O-β-D-glucopyranoside (8), quinovic acid 3β-O-α-L-rhamnoside (9), α-amyrin (10), 3-oxoquinovic acid (11), ursolic acid (12), hederagenin (13), rotundic acid (14), clethric acid (15), and naucleficine (16) by the analysis of their NMR spectroscopic data including 2D NMR spectra and by comparison of their spectroscopic data reported in the literature. Compounds 1 and 3 were isolated for the first time in the genus Nauclea, and compound 2 was isolated for the first time from the Rubiaceae family. Complete NMR assignations for 1 have been published for the first time.

• Journal of dental hygiene science
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• v.21 no.1
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• pp.38-44
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• 2021

Background: Dental caries and periodontal disease are bacterial infectious disease, mainly caused by plaque, a bacterial colony deposited on the tooth surface and gum tissue. Dental plaque disclosants easily stain the dental plaque, making them effective for scaling and tooth brushing education. As the erythrosine typically contained in dental plaque disclosants is highly cytotoxic, a low toxicity additive is needed. In this study, we aimed to examine the natural pigments with negligible cytotoxicity but can effectively stain the dental plaques for use in dental plaque disclosants. Methods: The pigmentation of eight types of natural pigments was tested on bovine tongue and teeth, as well as on head and neck tissue sections of experimental ICR mice. The cytotoxicity of gingival epithelial cells was measured via MTT assay. Pigmentation was performed on the bovine tongue and tooth surface. Pigmentation in the oral environment was observed in four mandibular incisors. A 2 Tone was used as a control. Results: Of the eight types of natural pigments, purple and blue pigments were effective in coloring dental plaques on the enamel surface as well as in the head and neck tissue sections. Additionally, purple and blue pigments were visible on the surface of the bovine tongue. Red, pink, orange, green, purple, and yellow pigments showed strong cytotoxicity, whereas brown and blue pigments had relatively low cytotoxicity. Blue pigment was effective in staining the dental plaque of four mandibular incisors. Conclusion: We suggest that the blue pigment derived from Gardenia jasminoides Ellis (Rubiaceae), which is effective for coloring dental plaques and has low cytotoxicity, is useful as a naturally derived dental disclosant.

• Korean Journal of Plant Resources
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• v.35 no.2
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• pp.242-247
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• 2022

Richardia brasiliensis Gomes was found in agricultural land in Susan-ri, Seogwipo-si, Jeju-do. Richardia L. is closely related to Diodia L. in Korea, those are confirmed to features of calyx, collora and fruit. This species is similar to R. scabra L., but it differs morphologically from the letter in surface structure of mericarp. The mericarp of R. brasiliensis has line like kneel at the adaxial, whereas R. scabra has groove at the adaxial. R. brasiliensis is recorded for the first time in this study and a morphological description, distribution map, and photographs are presented.

• Natural Product Sciences
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• v.11 no.3
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• pp.145-149
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• 2005

A methanol soluble extract from the dried hooks and stems of Uncaria rhynchophylla showed a strong inhibitory activity against monoamine oxidase in mouse brain. Using a bioassay-guided purification of this extract, a known ${\beta}-carboline$ type alkaloid, harman (1), was obtained as an active constituent. In addition, five known indole alkaloids, isocorynoxeine (2), isorhynchophylline (3), corynoxeine (4), cadambine (5), and $3{\alpha}-dihydrocadambine$ (6), were isolated and found to be weakly active or inactive.

• Korean Journal of Plant Resources
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• v.2 no.2
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• pp.259-278
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• 1989

The plants medicinal resources of Mt. Eb-aon were investifeted 18times from JuLy, 1988 to August, 1989. In orther to analyze the vegeta-tion of Eb-am mountain area, medical wild plants structure and distr-ibution. Medical wild Plants of Eb-am mountain consisted of 100 familis, 337 species in alL. The resources of important herb drugs were, Graminea, Liliaceae, Molaceae, Polygonaceae, Ranunculaceae, Brassicaceae, Rosaceae, Drupaceae, Fabaecae, Apiaceae, Labiatae, Solanaceae, Scrophulariaceae, Rubiaceae, CampanuLaceae, ComposLtae, The herb drufs were Comparatively more than in other mountains in our country.

• Analytical Science and Technology
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• v.6 no.4
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• pp.395-399
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• 1993

Corynoxeine, rhynchophylline, isocorynoxeine, isorhychophylline were isolated from Uncaria hooks and determined by HPLC. Their contents were : isocorynoxeine 0.21%, isorhynchophylline 0.16%, corynoxeine 0.28%, rhynchophylline 0.23%, respectively. Corynoxeine and isocorynoxeine, rhynchophylline and isorhychophylline were interconverted each other by heat treatment.

• Natural Product Sciences
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• v.6 no.1
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• pp.40-43
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• 2000

The chemical investigation on the cell suspension culture of Morinda elliptica L. yielded eight anthraquinones, two of which, anthragallol-1,2-dimethyl ether (3) and purpurin-1-methyl ether (4), have not been isolated from the original plant. Other compounds isolated include nordamnacanthal (1), alizarin-1-methyl ether (2), rubiadin (5), soranjidiol (6), $lucidin-{\omega}-methyl$ ether (7), and morindone (8). The structures of anthraquinones were established based on spectral studies.

• Bulletin of the Korean Chemical Society
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• v.35 no.11
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• pp.3232-3238
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• 2014

Mollugin has been reported to have various biological activities including antineoplastic, antitumor, antiviral against the hepatitis B virus, anti-aging and antimutagenic activities. An effective and concise synthesis of mollugin in two steps including kinetic control from the cheap starting material 1,4-naphthoquinone has been introduced, and mollugin derivatives thus prepared are screened for their inhibition ability against the hepatitis C virus (HCV) and the dihydrobenzochromene structure might be an additional anti-HCV agent as a new leading compound.