• The Korean Journal of Emergency Medical Services
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• v.14 no.3
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• pp.5-11
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• 2010

Purpose: This study was to clarify correlation between en route distance and role time on call received hours. Methods: Data on en route distance(dependent variable), role time(independent variable) from 387 prehospital care reports documented by EMS in Kyonggi Provincial Fire and Disaster Headquarters and Seoul Metropolitan Fire and Disaster Department between 21 and 10 June 2010 were randomly chosen for simple regression analysis using Windows SPSS 12. OK. This analysis was conducted nine times on unit hour divided to eight call received and overall. Results: Statistically significant regression equations( Y=2.414+1.206X for 09:00~11:59, Y=3.753+.662X for 12:00~14:59, Y=2.215+1.458X for 15:00~17:59, Y=2.600+.822X for 21:00~23:59, Y=5. 445+.263X for overall) were derieved from the data. Conclusion: These equations having linear relationship may be utilized as a method for system status management to effectively response to emergency call.

• Archives of Pharmacal Research
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• v.18 no.3
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• pp.141-145
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• 1995

Omeprazole, a proton pump inhibitor, was given intravenously (iv), orally (po), intraperitoneally (ip), hepatoportalvenously (pv), and intrarectally (ir) to rats at a dose of 72mg/kg in order to investigate the bioavailability of the drug, The extent of bioavailabilities of omeprazole administered through pv, ip, po, and ir routes were 88.5, 79.4, 40,8, and 38.7%, respectively. Pharmacokinetic analysis in this study and literatures (Regardh et al., 1985 : Watanabe et al., 1994) implied significant dose-dependency in hepatic first-pass metabolism, clearance and distribution, and acidic degradation in gastric fluid. The high bioavailability from the pv administration (88.5%) means that only 11.5% of dose was extracted by the first-pass metabolism through the liver at this dose (72 mg/kg). The low bioavailability from the oral administration (40.8%) in spite of minor hepatic first-pass extraction indicates low transport of the drug from GI lumen to portal vein. From the literature (Pilbrant and Cederberg, 1985), acidic degradation in gastric fluid was considered to be the major cause of the low transport. Thus, enteric coating of oral preparations would enhance the oral bioavailability substantially. The bioavailability of the drug from the rectal route, in which acidic degradation and hepatic first-pass metabolism may not occur, was low (38.7%) but comparable to that from the oral route (40.8 %) indicating poor transport across the rectal membrane. In this case, addition of an appropriate absorption enhancer would improve the bioavailability. Rectal route seems to be an possible alternative to the conventional oral route for omeprazole administration.

• Journal of Korean Society of Transportation
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• v.20 no.3
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• pp.129-147
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• 2002

This paper presents a variational equality formulation by Providing new dynamic route choice condition for a link-based dynamic traffic assignment model. The concepts of used paths, used links, used departure times are employed to derive a new link-based dynamic route choice condition. The route choice condition is formulated as a time-dependent variational equality problem and necessity and sufficiency conditions are provided to prove equivalence of the variational equality model. A solution algorithm is proposed based on physical network approach and diagonalization technique. An asymmetric network computational study shows that ideal dynamic-user optimal route condition is satisfied when the length of each time interval is shortened. The I-394 corridor study shows that more than 93% of computational speed improved compared to conventional variational inequality approach, and furthermore as the larger network size, the more computational performance can be expected. This paper concludes that the variational equality could be a promising approach for real-time application of a dynamic traffic assignment model based on fast computational performance.

• Journal of Korean Society of Transportation
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• v.24 no.7 s.93
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• pp.65-79
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• 2006

The ATIS(Advance Traveler Information System), as one part of ITS, is a system aiming to disperse traffic volume on transportation networks by providing traffic information to transportation users on pre-trip and en-route trips. One of tools in ATIS is usage of VMS(Variable Message Signs). It provides to the drivers with direct information about state of processing direction. which is considered as the most effective method in ATIS. The purposes of providing VMS information are classified two categories. One is to provide simple information to drivers for their convenience. The other is to manage traffic demand to improve transportation network performance. However, for more effective and reliable VMS information, several strategies should be taken into account. The main VMS management strategy is "Traffic Diversion Strategy for minimum delay" when traffic congestion or incident are occurred. For effective operation. firstly. reasonable diversion traffic volume is determined by network traffic condition Secondly, it is necessary to make providing information strategy which reflects driver response behavior for controling diversion traffic volume. This paper focuses on the providing real-time route guidance information by VMS when congestion is occurred by the incidents. This sturdy estimates time-dependent system optimal diversion rate that inflects travel time and queue lengths using traffic flow simulation model on base Cellular Automata. In addition, route choice behavior models are developed using binary logit model for traffic information variable by traffic system controller. Finally, this study provides time-dependent VMS massage contents and degree of providing information in order to optimize the traffic flow.

• Journal of Korean Society of Transportation
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• v.21 no.6
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• pp.77-88
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• 2003

This paper proposes a solution algorithm for solving a multi-class analytical DTA model. In the DTA model, three traveler classes are classified according to different assumptions of traveler's route choice behavior: including fixed route, Stochastic Dynamic User Optimum(SDUO), and Dynamic User Optimum(DUO). To solve this DTA model, variables of link flow and exit flow are represented solely by inflow. The resulting Linear Program(LP) subproblem in the inner iteration is solved as a typical time-dependent shortest route problem over a physical network. Accordingly, the required time-space network expansion in solving DTA models is no longer needed.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.30 no.5
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• pp.425-433
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• 2012

Dijkstra's algorithm is one of well-known methods to find shortest paths over a network. However, more research on $A^*$ algorithm is necessary to discover the shortest route to a goal point with the heuristic information rather than Dijkstra's algorithm which aims to find a path considering only the shortest distance to any point for an optimal path search. Therefore, in this paper, we compared Dijkstra's algorithm and $A^*$ algorithm for bicycle route selection. For this purpose, the horizontal distance according to slope angle and average speed were calculated based on factors which influence bicycle route selection. And bicycle routes were selected considering the shortest distance or time-dependent shortest path using Dijkstra's or $A^*$ algorithm. The result indicated that the $A^*$ algorithm performs faster than Dijkstra's algorithm on processing time in large study areas. For the future, optimal path selection algorithm can be used for bicycle route plan or a real-time mobile services.

• International conference on construction engineering and project management
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• 2020.12a
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• pp.510-519
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• 2020

Within an intelligent automated cyber-physical system, the realization of the autonomous mechanism for data collection, data integration, and data analysis plays a critical role in the design, development, operation, and maintenance of such a system. This construct is particularly vital for fault-tolerant route-finding systems that rely on the imprecise GPS location of the vehicles to properly operate, timely plan, and continuously produce informative feedback to the user. More essentially, the integration of digital twins with cyber-physical route-finding systems has been overlooked in intelligent transportation services with the capacity to construct the network routes solely from the locations of the operating vehicles. To address this limitation, the present study proposes a conceptual architecture that employs digital twin to autonomously maintain, update, and manage intelligent transportation systems. This virtual management simulation can improve the accuracy of time-of-arrival prediction based on auto-generated routes on which the vehicle's real-time location is mapped. To that end, first, an intelligent transportation system was developed based on two primary mechanisms: 1) an automated route finding process in which predictive data-driven models (i.e., regularized least-squares regression) can elicit the geometry and direction of the routes of the transportation network from the cloud of geotagged data points of the operating vehicles and 2) an intelligent mapping process capable of accurately locating the vehicles on the map whereby their arrival times to any point on the route can be estimated. Afterward, the digital representations of the physical entities (i.e., vehicles and routes) were simulated based on the auto-generated routes and the vehicles' locations in near-real-time. Finally, the feasibility and usability of the presented conceptual framework were evaluated through the comparison between the primary characteristics of the physical entities with their digital representations. The proposed architecture can be used by the vehicle-tracking applications dependent on geotagged data for digital mapping and location tracking of vehicles under a systematic comparison and simulation cyber-physical system.

• Archives of Reconstructive Microsurgery
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• v.4 no.1
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• pp.9-15
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• 1995

Free vascularized composite tissue transfer is more frequently underwent for reconstruction of complicated tissue defects with the recent advance of microsurgery. But postoperative result was not satifactory because of donor site morbidity, flap bulkiness and cosmetic problem. So would no longer be a problem if we can obtain the exact donor tissue required for the recipient site as allotransplantation and designing the flap. Allotransplantation has been resolved with the recent development of immunosuppressive agents, while reconstruction has made great progress with the refinement of microsurgical techniques in the last 20 years. The final sucess or failure of the operative procedure in transplantation is so utterly dependent no the availability of strategies that can control the immune system effectively, selectively, safely to allow allotransplantation of a nonvital body part. 1 used 2 strains of rats, BUF and LEW, for the limb allotransplantation as a composite tissue transfer. The primary goal of this program is to improve results in clinical transplantation by accelerating the transformation of new immunological knowledge into useful medicine. Two of the most promising new immunosuppressive compounds are FK-t06(FK) and rapamycin(RPM). Both drugs are antibiotic macrolide fungal fermentation products that presumably suppress the immune system in ways similar to cyclosporin(CyA). This study shows that two new immunosuppressive drugs compare the immunosuppressive activity and effectiveness of FK-506 and RPM for prevention of the limb allograft rejection in the rat. Additional experiments investigate the dose, route of administration and histologic findings. These data demonstrates that rapamycin is far more potent and effective than FK-506 when both compounds are administered by the intraperitoneal route, as well as prolonged graft survival significantly in a dose-route dependent manner. These results lead to the view that vascularized allograft composite tissue transfer can become a reality with the expectation of possible future application in reconstructive surgery of humans.

• Journal of the Korean Ceramic Society
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• v.51 no.5
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• pp.424-429
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• 2014

YAG:$Ce^{3+}$ phosphor powders were synthesized using $Al(OH)_3$ seeds by means of a PVA-polymer-solution route. Various types of PVA with different molecular weights (different polymerization) were used. All dried precursor gels were calcined at $500^{\circ}C$ and then heated at $1500^{\circ}C$ in a mix of nitrogen and hydrogen gases. The final powders were characterized via XRD, SEM, PSA, PL, and PKG analyses. The phosphor properties and morphologies of the synthesized powders were dependent on the PVA type. As the molecular weight of the PVA was increased, the particle size gradually decreased with agglomeration, and the luminous intensity of the phosphor increased. However, the phosphor powder prepared from the PVA exhibiting very high molecular weight, showed a 531 nm (blue) shift from the 541 nm (yellow) wavelength of the YAG:$Ce^{3+}$ phosphor. Finally, the synthesized YAG:$Ce^{3+}$ phosphor powder prepared from the PVA with 89,000 - 98,000 molecular weight showed phosphor properties similar to those of a commercial phosphor powder, but without a post-treatment process.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.35 no.4
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• pp.281-290
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• 2017

Transportation plays a vital role in sustainable development, and moreover, bulk transportation provides cost effective movement of goods and human beings with less environmental issues. Nepal is a developing country with increasing urbanization and transportation demands. The growing interest of China to connect with Southeast Asia through Nepal has led to ambitious project proposal of Rasuwa Gadhi to Birgunj Railways, which is the shortest route from China to India. Lack of updated geospatial data has lead the concerned authorities in Nepal to be dependent on analysis and proposals from donor nations. Taking such considerations, based on GIS and free data, this study explores optimal routes to connect cites using slope and land cover. Based on reclassified slope, two shortest optimal routes were found. One passing through Baireni in Dhading and another through Kathmandu towards Birgunj with length of around 172 Kilometers. The study shows that available open source data can be used of preliminary feasibility studies and yet shows limitations for detailed economy based planning. Development and use of high resolution updated geospatial data is of high necessity for Nepal to become self-sustained in planning of development works.