• Proceedings of the KIEE Conference
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• 2002.11a
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• pp.13-15
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• 2002

The trench MOSFET structure is characterized by reduced on-resistance due to elimination of $R_{JFET}$ and high packing density. An analytical calculation of Ron as the sum of $R_{ch}$ and $R_{epi}$ has been reported previously for the trench MOSFET structure. However, the accumulation layer resistance may not be neglected for Trench MOSFET especially for a relatively large value of the cell spacing, where a major contribution to Ron comes from Ra as the simulation results in this paper shows.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.6 no.1
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• pp.71-87
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• 1993

• The KSFM Journal of Fluid Machinery
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• v.9 no.1 s.34
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• pp.56-60
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• 2006

• Communications of the Korean Institute of Information Scientists and Engineers
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• v.27 no.11
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• pp.58-64
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• 2009

• Proceedings of the Korean Magnestics Society Conference
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• 2008.12a
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• pp.179.1-179.1
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• 2008

• Journal of Daesoon Thought and the Religions of East Asia
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• v.2 no.1
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• pp.167-168
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• 2022

• Journal of Korean Medical classics
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• v.13 no.1
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• pp.102-116
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• 2000

In Cheon Won Gi Dae Ron(天元紀大論), Cheon(大) means Nature, Won(元) means sources, Gi(紀) is Gang Gi(綱紀) that means rules or regulations, so Cheon Won Gi(天元紀) means sources and rules of change that make Nature phenomenons. This volume treats of cause that weather change of Nature caused by, and its general rules, and presents fundamental notions and systems of measuring of 'Five elements' evolutions and Six kinds of natural factors(五運六氣)'. So named Cheon Won Gi Dae Ron(天元紀大論). This article of the research on the Cheon Won Gi Dae Ron(天元紀大論) can be divided into 3 chapters. Chapter 1 presents a theory that the principle of changes of creations' birth, groth and extinction is complished by sympathizing with Hyeong(形) of Ji(地) and Gi(氣) of Cheon(大) by rules of movement of O Un Yum Yang(五運陰陽). Chapter 2 presents theories that Tae Heo(太虛) makes Won Gi(元氣), and this Won Gi(元氣) makes the change of creations' birth, groth and extinction, and movement of O Un(五運) controls creation of nature. And treats of that 'excessive and short(太過不及)' that is made by a quality of Gi(氣) and ups and dons of Hyeong(形) controls weather of year. In Chapter 3, Cheon O Ji Yuk(天五地六) regard six and five as Yong(用). And A Cycle that movment that sympathizing with O Un(五運) and Yuk Gi(六氣) is Il Gi(一氣) as 30 years, and Il Ju(一周) as 60 years. And presents that O Un(五運) and Yuk Gi(六氣) that Gan Ji(干支) control.

• Journal of Korean Medical classics
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• v.7
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• pp.232-268
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• 1994

According as we look around a notion of LM-YANG(陰陽) in NAE-KYUNG(內徑) or ancient for example the Book of Changes(周易), we will find that the principle of UM-YANG of philosophy in ancient china was applied medical science by NAE-KYUNG, and Chung-Kyung(仲景) connected principle of UM-YANG in NAE-KYUNG to demonstration and medical treatment(辨證施治) of SANG-HAN disease(傷寒病). According as we look around 3UM-3YANG(三陰三陽) in NAE-KYUNG and various theories of another scholar connected 3UM-3YANG of SANG-HAN-RON(傷寒論), we can know that the whole of SANG-HAN-YUK-KYUNG(傷寒六經) cannot explain by a some conception, we cannot understand precisely rear meaning of SANG-HAN-YUK-KYUNG until theories-JANG-BU(臟腑), GYUNG-RAK(經絡), GI-HWA(氣化), a reigon, a layer, and so on-are studied totally. Therefore 3UM-3YANG of SANG-HAN-RON(傷寒論) is basically the thing of specialization UM-YANG, eventually UM-YANG are two functional characteristics in human body. It is specialized to 3UM-3YANG by spatial and time criteria. When we consider a question in its aspect, YUK-KYUNG is synthetic six classifications of human body's functional system that include(3UM-3YANG)GYUNG-RAK, related JANG-BU, distributional area of GYUNG-RAK, vicissitude of UM-YANG, more or less of GEE-HYUL(氣血), function of GAE-HAB-CHUL(開闔樞), and the like; and disease of YUK-KYUNG of SANG-HAN-RON are the very six types of disease that appeared by dint of mal function of each synthetic functional system.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.25 no.3
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• pp.88-96
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• 2012

Objectives : We investigated the skin properties on the periorbital region and cheek of Korean female according to age pattern by 7year based on Sang Go Cheun Jin Ron (上古天眞論) in So Moon (素問,) Methods : 49 Korean females, aged 21-56 years ($39.54{\pm}10.04$ years) were participated in this study. We measured the skin properties of periorbital region and cheek with SkinTouch (Amorepacific, Korea). Skin moisture, sebum, elasticity, lightness, roughness, area of wrinkle, depth of wrinkle were assessed. Results : Differences were noticed depending on the site and age. The level of moisture was higher on the eyelid than crow's feet. The level of lightness and elasticity were lower on the periorbital region than cheek. Skin lightness was highest on group1(under 28y) and lowest on group5(over 49y). Skin roughness was highest on group1(under 28y) and lowest on group4(over 42y under 49y). The level of wrinkle are was lowest on group1(under 28y) and highest on group 5(over49y). The level of wrinkle depth was lowest on group1(under 28y) and highest on group 4(over 42y under 49y). Conclusion : Unique aging pattern by 7 years of female is reflected to diverse skin properties of eyes. It can be possible to apply the theory on Sang Go Cheun Jin Ron (上古天眞論) to practical use in dermatology and cosmetic.

• Genomics & Informatics
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• v.14 no.2
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• pp.53-61
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• 2016

Toxoplasma gondii is an intracellular Apicomplexan parasite and a causative agent of toxoplasmosis in human. It causes encephalitis, uveitis, chorioretinitis, and congenital infection. T. gondii invades the host cell by forming a moving junction (MJ) complex. This complex formation is initiated by intermolecular interactions between the two secretory parasitic proteins-namely, apical membrane antigen 1 (AMA1) and rhoptry neck protein 2 (RON2) and is critically essential for the host invasion process. By this study, we propose two potential leads, NSC95522 and NSC179676 that can efficiently target the AMA1 hydrophobic cleft, which is a hotspot for targeting MJ complex formation. The proposed leads are the result of an exhaustive conformational search-based virtual screen with multilevel precision scoring of the docking affinities. These two compounds surpassed all the precision levels of docking and also the stringent post docking and cumulative molecular dynamics evaluations. Moreover, the backbone flexibility of hotspot residues in the hydrophobic cleft, which has been previously reported to be essential for accommodative binding of RON2 to AMA1, was also highly perturbed by these compounds. Furthermore, binding free energy calculations of these two compounds also revealed a significant affinity to AMA1. Machine learning approaches also predicted these two compounds to possess more relevant activities. Hence, these two leads, NSC95522 and NSC179676, may prove to be potential inhibitors targeting AMA1-RON2 complex formation towards combating toxoplasmosis.