• Title/Summary/Keyword: risk reduction factor

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Risk Factors for Lymphedema Patients (림프부종 환자에서의 위험 인자)

  • Jung, Gyou-Chul;Kim, Sun-Hyun;Yeom, Chang-Hwan
    • Journal of Hospice and Palliative Care
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    • v.8 no.2
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    • pp.156-162
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    • 2005
  • Purpose: Lymphedema is edema developing mainly in the arms and legs due to an abnormal lymphatic system, over one hundred millions of patient worldwide suffer from it. At present, prevention is the best treatment. Thus, It is important to know which patient are more pone to develop it in order to prevent it. By evaluating the risk factor for lymphedema, we intended to find the effective prevention. Methods: We have investigated that outpatients who chiefly complained of lymphedema visited the lymphedema clinic at one university hospital from September 1 in 2003 to August 31 in 2005. We evaluated the risk factor for lymphedema by questionnaires. Questionnaire consists of demographic data, disease factor, treatment factor, posttreatment factor. We evaluated the correlation between lymphedema with each factor. Results: The total number of patients was 50, 19 patients with breast cancer and 31 patients with cervical cancer. In terms of stages of edema, 12 patients were below stage 1 and 38 patients were above stage 2. The incidence of lymphangitis was more frequent, more obese and the impairment of the site of edema site more severe, the stage of cancer was higher in the patients higher than stage 2 than in the patients below stage 1 (P>0.05). Conclusion: Lymphedema is more severe when the cancer stage in higher, accompanying more frequent infections, more obesity and more impairment at the site of edema site. Above all, cancer stage and the impairment of edema site are impossible to correct but obesity and infection may be corrected. Therefore we speculate that we are able to protect the aggravation of edema by weight reduction and infection control.

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Development of Standard Risk Indicators for the Prevention of Serious Accidents in Mobile Crane Operations (Focused on Construction Industry) (이동식크레인 작업의 중대재해예방을 위한 표준 리스크 평가 지수 개발 (건설업을 중심으로))

  • Jonggook Choi;Jongwoo Lee
    • Journal of the Society of Disaster Information
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    • v.19 no.3
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    • pp.719-728
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    • 2023
  • Purpose: Mobile cranes are machines that contribute to high mortality, and the High Risk Factor (SIF) information, which analyzed 2,574 accidental deaths in the construction industry in the past 6 years (2016~2021), resulted in a total of 61 mobile crane accidents. Despite safety measures in the field, it is not used properly. In this study, we present standard risk assessment indicators that contribute to accident prevention. Method: Through expert interviews, fatal accident case analysis, field analysis, and literature research, we present the standard risk assessment index method of the 4M risk assessment method. Result: As a result of analyzing the risk assessment of eight sites, it was concluded that it cannot make a significant contribution to disaster prevention and should be applied as an improvement measure of the Standard Risk Assessment Index Law. Conclusion: Switching to the standard risk assessment index method at construction sites has been proposed to make it easier for health and safety personnel and workers to use, contributing to the reduction of accidents.

A Study on Disaster Risk Assessment in the Urban Open Spaces (도시 녹지 공간의 재해 위험도 평가 연구)

  • Yu, Joo-Eun
    • Journal of the Korean Institute of Landscape Architecture
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    • v.43 no.5
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    • pp.13-27
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    • 2015
  • This study examined disaster risk from climate change in urban open spaces. This study conducted an assessment depending on type of damage and type of open space, subcategorizing it into flood damage and wind damage, flat park and mountainous park, and classified the assessment items by type into natural factor, artificial factor, and social factor for the purpose of analysis. Our major findings from this study are as follows: To look at the standardized score for the disaster risk from flood damages in the case of a flat park, Asian Park was higher at 55.800 point than Seoul Forest at 51.775 point, and in the case of mountainous parks, Dogok Park was at 58.428 point and Baebongsan Park was at 58.374 point. To look at the standardized score for disaster risk from wind damage, in the case of a flat park, Asian Park was higher at 64.763 point than Seoul Forest at 61.054 point, and in the case of mountainous parks, Baebongsan Park was higher at 58.533 point than Dogok Park at 55.459 point. This study raised a question about the necessity for and value of this disaster risk assessment in open space from damages caused by climate change, established an assessment model for disaster risk from damages in open spaces only to attempt risk assessment. Disaster risk of urban green space was enhanced.

Deletion of GSTM1 and T1 Genes as a Risk Factor for Development of Acute Leukemia

  • Dunna, Nageswara Rao;Vure, Sugunakar;Sailaja, K.;Surekha, D.;Raghunadharao, D.;Rajappa, Senthil;Vishnupriya, S.
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.4
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    • pp.2221-2224
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    • 2013
  • The glutathione S-transferases (GSTs) are a family of enzymes involved in the detoxification of a wide range of chemicals, including important environmental carcinogens, as well as chemotherapeutic agents. In the present study 294 acute leukemia cases, comprising 152 of acute lymphocytic leukemia (ALL) and 142 of acute myeloid leukemia, and 251 control samples were analyzed for GSTM1 and GSTT1 polymorphisms through multiplex PCR methods. Significantly increased frequencies of GSTM1 null genotype (M0), GSTT1 null genotype (T0) and GST double null genotype (T0M0) were observed in the both ALL and AML cases as compared to controls. When data were analyzed with respect to clinical variables, increased mean levels of WBC, Blast %, LDH and significant reduction in DFS were observed in both ALL and AML cases with T0 genotype. In conclusion, absence of both GST M & GST T might confer increased risk of developing ALL or AML. The absence of GST enzyme might lead to oxidative stress and subsequent DNA damage resulting in genomic instability, a hallmark of acute leukemia. The GST enzyme deficiency might also exert impact on clinical prognosis leading to poorer DFS. Hence GST genotyping can be made mandatory in management of acute leukemia so that more aggressive therapy such as allogenic stem cell transplantation may be planned in the case of patients with a null genotype.

Development of A Quantitative Risk Assessment Model by BIM-based Risk Factor Extraction - Focusing on Falling Accidents - (BIM 기반 위험요소 도출을 통한 정량적 위험성 평가 모델 개발 - 떨어짐 사고를 중심으로 -)

  • Go, Huijea;Hyun, Jihun;Lee, Juhee;Ahn, Joseph
    • Korean Journal of Construction Engineering and Management
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    • v.23 no.4
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    • pp.15-25
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    • 2022
  • As the incidence and mortality of serious disasters in the construction industry are the highest, various efforts are being made in Korea to reduce them. Among them, risk assessment is used as data for disaster reduction measures and evaluation of risk factors at the construction stage. However, the existing risk assessment involves the subjectivity of the performer and is vulnerable to the domestic construction site. This study established a DB classification system for risk assessment with the aim of early identification and pre-removal of risks by quantitatively deriving risk factors using BIM in the risk assessment field and presents a methodology for risk assessment using BIM. Through this, prior removal of risks increases the safety of construction workers and reduces additional costs in the field of safety management. In addition, since it can be applied to new construction methods, it improves the understanding of project participants and becomes a tool for communication. This study proposes a framework for deriving quantitative risks based on BIM, and will be used as a base technology in the field of risk assessment using BIM in the future.

A Study on the Accident Consequences of High Pressure Pipelines by Applying Reduction Factors (감소인자 적용에 따른 고압가스배관의 사고피해영향에 관한 연구)

  • Lee, Dong Hyuck;Jung, Sang Yong;Ko, Sang Wook;Kim, Min Seop;Ko, Jae Wook
    • Journal of the Korean Institute of Gas
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    • v.16 no.5
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    • pp.1-6
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    • 2012
  • It becomes a more and more common practice to build facilities bigger and more integrated in an effort to optimize the process within limited resources and spaces. As the capacity of facilities increases, so does the flow rate and pressure. This in turn leads to a high consequence of accident. Not only are these facilities vulnerable to leakage because of their high pressure, but also subsequent fire and explosion can be threatening. For these reasons, there is an urgent need to come up with solutions to assess and minimize the damage from an accident. The Quantitative Risk Assessment(QRA) is one of the most efficient ways to solve problems on pressurized pipelines. The QRA can be re-enforced by applying reduction factors. In this study various types of accidents in a pressurized pipeline were evaluated. The damage from accidents were computed, then. Finally the reduction factors were very effective to decrease consequences of high pressure pipeline accidents.

Parents' Knowledge about Enterobiasis Might Be One of the Most Important Risk Factors for Enterobiasis in Children

  • Kim, Dong-Hee;Son, Hyun-Mi;Kim, Joo-Young;Cho, Min-Kyoung;Park, Mee-Kyung;Kang, Sin-Ye;Kim, Bo-Young;Yu, Hak-Sun
    • Parasites, Hosts and Diseases
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    • v.48 no.2
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    • pp.121-126
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    • 2010
  • To know the prevalence of Enterobius vermicularis infection and what are the most important risk factors, we evaluated the incidence and risk factors of enterobiasis among children attended in kindergartens in Busan metropolitan city, Republic of Korea. A total of 1,674 children from 21 kindergartens in 11 of 16 autonomous districts of Busan were evaluated for E. vermicularis infection by the cellotape anal swab technique. The overall egg-positive rate for E. vermicularis was 10.7% (179/1,674), and the prevalence of enterobiasis in each kindergarten ranged between 0% and 32.4%. There was an increasing tendency of the egg positive rate according to the population density; the higher the population density communities had, the higher egg-positive rate for E. vermicularis was detected (P = 0.001). Among personal hygiene factors involving children, thumb-sucking (P = 0.036) and fingernail-trimming (P = 0.024) were highly associated with enterobiasis. In addition, taking anthelmintic medications against E. vermicularis infection was strongly associated with enterobiasis (P = 0.014). Moreover, parents' knowledge of enterobiasis was correlated significantly with the incidence of enterobiasis of their children (P = 0.006). In conclusion, we need to consider not only personal hygiene but also parents' knowledge about enterobiasis as a factor in order to develop new strategies for elimination or to complete reduction of enterobiasis in Korea.

Reproductive Variables and Risk of Breast Malignant and Benign Tumours in Yunnan Province, China

  • Yanhua, Che;Geater, Alan;You, Jing;Li, Li;Shaoqiang, Zhou;Chongsuvivatwong, Virasakdi;Sriplung, Hutcha
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.5
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    • pp.2179-2184
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    • 2012
  • Introduction and aim: To compare reproductive factor influence on patients with pathological diagnosed malignant and benign tumor in the Breast Department, The First Peoples' Hospital of Kunming in Yunnan province, China. Methods: A hospital-based case-control study was conducted on 263 breast cancer (BC) cases and 457 non-breast cancer controls from 2009 to 2011. The cases and controls information on demographics, medical history, and reproductive characteristics variables were collected using a self-administered questionnaire and routine medical records. Histology of breast cancer tissue and benign breast lesion were documented by pathology reports. Since some variables in data analysis had zero count in at least one category, binomial-response GLM using the bias-reduction method was applied to estimate OR's and their 95% confidence intervals (95% CI). To adjust for age and menopause status, a compound variable comprising age and menopausal status was retained in the statistical models. Results: multivariate model analysis revealed significant independent positive associations of BC with short menstrual cycle, old age at first live birth, never breastfeeding, history of oral contraception experience, increased number of abortion, postmenopausal status, and nulliparity. Categorised by age and menopausal status, perimenopausal women had about 3-fold and postmenopausal women had more than 5-fold increased risk of BC compared to premenopausal women. Discussion and Conclusion: This study has confirmed the significant association of BC and estrogen related risk factors of breast cancer including longer menstrual cycle, older age of first live birth, never breastfeeding, nulliparity, and number of abortions more than one. The findings suggest that female hormonal factors, especially the trend of menopause status play a significant role in the development of BC in Yunnan women.

Obesity and chronic kidney disease: prevalence, mechanism, and management

  • Yim, Hyung Eun;Yoo, Kee Hwan
    • Clinical and Experimental Pediatrics
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    • v.64 no.10
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    • pp.511-518
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    • 2021
  • The prevalence of childhood obesity is increasing worldwide at an alarming rate. While obesity is known to increase a variety of cardiovascular and metabolic diseases, it also acts as a risk factor for the development and progression of chronic kidney disease (CKD). During childhood and adolescence, severe obesity is associated with an increased prevalence and incidence of the early stages of kidney disease. Importantly, children born to obese mothers are also at increased risk of developing obesity and CKD later in life. The potential mechanisms underlying the association between obesity and CKD include hemodynamic factors, metabolic effects, and lipid nephrotoxicity. Weight reduction via increased physical activity, caloric restriction, treatment with angiotensin-converting enzyme inhibitors, and judicious bariatric surgery can be used to control obesity and obesity-related kidney disease. Preventive strategies to halt the obesity epidemic in the healthcare community are needed to reduce the widespread deleterious consequences of obesity including CKD development and progression.

Relative SATD-based Minimum Risk Bayesian Framework for Fast Intra Decision of HEVC

  • Gwon, Daehyeok;Choi, Haechul
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.13 no.1
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    • pp.385-405
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    • 2019
  • High Efficiency Video Coding (HEVC) enables significantly improved compression performance relative to existing standards. However, the advance also requires high computational complexity. To accelerate the intra prediction mode decision, a minimum risk Bayesian classification framework is introduced. The classifier selects a small number of candidate modes to be evaluated by a rate-distortion optimization process using the sum of absolute Hadamard transformed difference (SATD). Moreover, the proposed method provides a loss factor that is a good trade-off model between computational complexity and coding efficiency. Experimental results show that the proposed method achieves a 31.54% average reduction in the encoding run time with a negligible coding loss of 0.93% BD-rate relative to HEVC test model 16.6 for the Intra_Main common test condition.