• Asian Pacific Journal of Cancer Prevention
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• 제15권24호
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• pp.10683-10690
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• 2015

The big gap between efficacy of population level prevention and expectations due to heterogeneity and complexity of cancer etiologic factors calls for selective yet personalized interventions based on effective risk assessment. This paper documents our research protocol aimed at refining and validating a two-stage and web-based cancer risk assessment tool, from a tentative one in use by an ongoing project, capable of identifying individuals at elevated risk for one or more types of the 80% leading cancers in rural China with adequate sensitivity and specificity and featuring low cost, easy application and cultural and technical sensitivity for farmers and village doctors. The protocol adopted a modified population-based case control design using 72, 000 non-patients as controls, 2, 200 cancer patients as cases, and another 600 patients as cases for external validation. Factors taken into account comprised 8 domains including diet and nutrition, risk behaviors, family history, precancerous diseases, related medical procedures, exposure to environment hazards, mood and feelings, physical activities and anthropologic and biologic factors. Modeling stresses explored various methodologies like empirical analysis, logistic regression, neuro-network analysis, decision theory and both internal and external validation using concordance statistics, predictive values, etc..

• Asian Pacific Journal of Cancer Prevention
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• 제14권5호
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• pp.3281-3288
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• 2013

Background: Breast cancer is the leading cause of cancer-related deaths in women. Despite being associated with high morbidity and mortality, breast cancer is a disease that can be diagnosed and treated early. Materials and Methods: In this cross-sectional study of 321 women, data were collected by Questionnaire, Breast Cancer Risk Assessment Form and Champion's Health Belief Model Scale. Mann-Whitney U, Kruskal-Wallis, Chisquared tests and logistic regression were used in the statistical analysis. Results: It was found that only 2.2% of women have high and very high risk levels of breast cancer risk. There is a positive correlation between early diagnosis techniques and Health Belief Model Sub-Dimension scores which are sensibility, health motivation, BSE (Breast self-examination) self-efficient perception and negative correlation between mammography barrier score and BSE barrier score (p 0.05). When factors for not having BSE were examined, it was determined that the women who do not have information about breast cancer and the women who smoke have a higher risk of not having BSE. Conclusions: It is important to determine health beliefs and breast cancer risk levels of women to increase the frequency of early diagnosis. Women's health beliefs are thought to be a good guide for planning health education programs for nurses working in this area.

• 한국수자원학회논문집
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• 제42권8호
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• pp.591-605
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• 2009

본 연구에서는 하천제방의 침식, 침투영향을 고려한 위험도 및 통합위험도를 산정하였다. 이를 위해 추계학적 강우변동 생성기법을 이용하여 생성된 태풍기와 장마기별 유량 및 수위수문곡선을 활용하여 하천제방에 대한 침식, 침투 그리고 통합 위험도를 산정하였다. 침식에 대한 하천제방의 위험도는 허용 소류력을 이용하여 평가하였고 침투류 해석은 각 제방별로 대표 제방단면을 선정 후 SEEP/W 모형을 통해 해석을 실시하였으며 한계동수경사법을 이용한 MFOSM 분석을 통해 제방의 침투붕괴 위험도를 산정하였다. 본 연구에서는 확정론적 분석방법과 달리 정량적인 위험도를 산정할 수 있었고 실제 강우 변동의 특성 및 다양한 제방파괴 요인을 반영하였으며, 이를 하나의 위험도로 통합하여 제시하고 있으므로 본 연구모형의 결과는 그 적용성에 있어 매우 유용할 것으로 판단된다. 본 연구모형은 향후 홍수에 대한 제방파괴 위험지점 파악 및 제내지 홍수위험도와 연계한 홍수보험, 주민대피지도 구축 등에 활용 될 수 있어 유역의 홍수통합관리시 효율적이고 체계적인 대책수립에 크게 기여할 것으로 판단된다.

• 해양환경안전학회지
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• 제25권6호
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• pp.635-641
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• 2019

서남해 해상풍력발전단지 내 선박 통항 금지와 조업 제한으로 인해 사업자와 어민간의 갈등이 심화되고 있다. 이러한 문제 해결을 위하여 국내에서도 유럽의 해상풍력발전단지와 같이 발전단지 내 선박 통항과 어로작업 허용을 검토하고 있다. 이 연구는 서남해 해상풍력발전단지 내 선박 통항을 가정하여 항로의 형태에 따른 해상교통위험도 발생비율을 ES 모델과 IWRAP을 이용하여 분석하였다. 또한, 항로의 형태(십자형 항로 및 격자형 항로)와 선박 통항량(현재, 3배, 5배, 10배)에 변화를 주어 위험도를 정량적으로 평가하였다. 주요 평가결과는 다음과 같다. 현재의 교통량에서 십자형 항로와 격자형 항로를 운영할 경우 조선부담감(종합환경스트레스치가 750 이상)이 높은 구간은 발생하지 않았으며, 연간 충돌확률도 큰 차이가 발생하지 않았다. 그러나 통항량이 현재보다 3배, 5배, 10배 증가함에 따라 교차지점에서 조선부담감과 연간 충돌확률이 급격히 증가함을 확인하였으며, 이를 통해 격자형 항로에서 교통류 분리를 통해 위험도를 효과적으로 분산시킬 수 있다는 것을 알 수 있었다. 본 연구의 결과는 서남해 해상풍력발전단지 내에서 항로설정, 항로운영방식, 안전대책 등에 활용이 가능할 것으로 기대된다.

• 한국식품과학회지
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• 제50권6호
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• pp.621-628
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• 2018

본 연구에서는 육포제조 시 사용된 양념의 여부 및 포장 방법에 따라 C. perfringens에 의한 육포의 안전 관리방안을 위해 정량적 미생물 위해평가를 수행하였다. 서울소재 대형마트 및 재래 시장에서 판매되는 275종의 오리지널 및 양념 육포에서 C. perfringens의 오염수준을 분석한 결과, 모든 제품에서 C. perfringens는 검출되지 않았으나 보관온도(10, 17, 25, $35^{\circ}C$)에서 C. perfringens 오염되었을 경우 포장조건(호기/진공)을 달리한 오리지널 및 양념 육포에서 모두 생존하는 것으로 나타났다. 육포에 @RISK를 활용한 위해도 추정결과, 진공포장 된 양념 육포에서 식중독 발생확률이 $2.77{\times}10^{-16}$으로 추정되었다. 또한 FDA-iRISK를 활용하여 육포의 위해도 및 관리순위를 비교한 결과, 진공포장된 양념 육포의 섭취를 통하여 C. perfringens에 의해 질병 발생확률과 질병에 의한 부담정도(DALYs)도 또한 가장 큰 것으로 나타났다. 포장조건(호기/진공)을 달리한 오리지널/양념 제품 중 진공포장된 양념 육포에서 C. perfringens에 의한 식중독 발생 가능성이 상대적으로 가장 높아 우선관리 대상임을 알 수 있었지만, 전반적으로 C. perfringens가 오염된 육포의 섭취에 의한 식중독 발생가능성은 매우 낮았다. 본 연구결과는 현재 육포에서 C. perfringens의 음성으로 관리하는 미생물학적 기준설정 제고에 대한 과학적 근거자료로 활용 할 수 있을 것으로 사료된다.

• Journal of Information Technology Applications and Management
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• 제11권2호
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• pp.15-27
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• 2004

Most software projects inevitably involve various types and degrees of uncertainty. Without proper risk assessment and coordination, software projects can easily run out of control and consume significant additional resource. Thus, risk management techniques are critical issues to information system researchers. Previous empirical studies of U.S. software firms support the adoption of development standardization and user requirement analysis techniques in risk-based software project management. Using data collected from software projects developed in Korea during 1999-2000, we conduct a comparative study to determine how risk management strategies impact software product and process performance in countries with dissimilar IT capabilities. In addition, we offer an alternative conceptualization of residual performance risk. We show that the use of residual performance risk as an intervening variable is inappropriate in IT developing countries like Korea where the role of late stage risk control remedies are critical. A revised model is proposed that generates more reliable empirical implications for Korean software projects.

• 한국안전학회지
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• 제10권1호
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• pp.56-63
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• 1995

Two methods of the numerical method of CPQRA(Chemical Process Quantitative Risk Analysis) and the manual method of IAEA(International Atomic Energy Agency) were used to estimate the individual risk and societal risk around the chemical plant. Where, the CPQRA is introduced to verify the theoritical background of the manual of international atomic energy agency. The Gaussian plume model which has a weather stability class D with velocity of 5m/s was applied to calculate dispersion of hazard material. Also, 8-point method was employed to the effects of accidents for wind distribution. Furthermore, historical record, FTA(Fault Tree Analysis) and ETA(Event Tree Analysis) were used to estimate the probability or frequency of accidents. Eventually, the individual risk shows isorisk contour and the societal risk shows F-N curve around hazard facility, especially in chemical plants. Caulculated results, which both individual and societal risk, by using IAEA manual show simillar results to those of calculation by numerical method of CPQRA.

• 기술사
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• 제34권5호
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• pp.77-81
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• 2001

The industrial accident in subway of late is increasingly coming to the front as a serious problem of society because a scale of industrial accident is a large size, and powerfulness, while the percent of accident is decreasing as a result of industrial facilities with the largeness of equipment, automation, and high horse-powering. In this paper, a study on the estimation of accident loss prevention cost and risk analysis in subway construction is proposed as an alternative to the techniques currently used in the general construction projects safety. Then the concept of risk evaluation using a risk assessment model is presented to drive value of risk and numerical example for risk analysis. A means for this does grasp the importance of educational factor by way of analyzing the causes of accident through statistical data of labor department, emphasizing the necessity and the importance of safety education, being helpful to act safety by decreasing insecure activity which ranks the majority of accident causes with putting the education program, form, method into practice that are suitable for a place of business.

• Journal of Multimedia Information System
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• 제8권4호
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• pp.259-266
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• 2021

Security vulnerabilities have been reported in major design software systems such as Adobe Photoshop and Illustrator, which are recognized as de facto standard design tools in most of the design industries. Companies need to evaluate and manage their risk levels posed by those vulnerabilities, so that they could mitigate the potential security bridges in advance. In general, security vulnerabilities are discovered throughout their life cycles repeatedly if software systems are continually used. Hence, in this study, we empirically analyze risk levels for the three major graphical design software systems, namely Photoshop, Illustrator and GIMP with respect to a software vulnerability discovery model. The analysis reveals that the Alhazmi-Malaiya Logistic model tends to describe the vulnerability discovery patterns significantly. This indicates that the vulnerability discovery model makes it possible to predict vulnerability discovery in advance for the software systems. Also, we found that none of the examined vulnerabilities requires even a single authentication step for successful attacks, which suggests that adding an authentication process in software systems dramatically reduce the probability of exploitations. The analysis also discloses that, for all the three software systems, the predictions with evenly distributed and daily based datasets perform better than the estimations with the datasets of vulnerability reporting dates only. The observed outcome from the analysis allows software development managers to prepare proactively for a hostile environment by deploying necessary resources before the expected time of vulnerability discovery. In addition, it can periodically remind designers who use the software systems to be aware of security risk, related to their digital work environments.

• The Korean Journal of Pain
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• 제33권2호
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• pp.153-165
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• 2020

Background: Well-validated risk prediction models help to identify individuals at high risk of diseases and suggest preventive measures. A recent systematic review reported lack of validated prediction models for low back pain (LBP). We aimed to develop prediction models to estimate the 8-year risk of developing LBP and its recurrence. Methods: A population based prospective cohort study using data from 435,968 participants in the National Health Insurance Service-National Sample Cohort enrolled from 2002 to 2010. We used Cox proportional hazards models. Results: During median follow-up period of 8.4 years, there were 143,396 (32.9%) first onset LBP cases. The prediction model of first onset consisted of age, sex, income grade, alcohol consumption, physical exercise, body mass index (BMI), total cholesterol, blood pressure, and medical history of diseases. The model of 5-year recurrence risk was comprised of age, sex, income grade, BMI, length of prescription, and medical history of diseases. The Harrell's C-statistic was 0.812 (95% confidence interval [CI], 0.804-0.820) and 0.916 (95% CI, 0.907-0.924) in validation cohorts of LBP onset and recurrence models, respectively. Age, disc degeneration, and sex conferred the highest risk points for onset, whereas age, spondylolisthesis, and disc degeneration conferred the highest risk for recurrence. Conclusions: LBP risk prediction models and simplified risk scores have been developed and validated using data from general medical practice. This study also offers an opportunity for external validation and updating of the models by incorporating other risk predictors in other settings, especially in this era of precision medicine.