• Molecules and Cells
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• 제41권12호
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• pp.1024-1032
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• 2018

The central mechanisms coordinating growth and sexual maturation are well conserved across invertebrates and vertebrates. Although mutations in the gene encoding makorin RING finger protein 3 (mkrn3) are associated with central precocious puberty in humans, a causal relationship has not been elucidated. Here, we examined the role of mkrn1, a Drosophila ortholog of mammalian makorin genes, in the regulation of developmental timing. Loss of MKRN1 in $mkrn1^{exS}$ prolonged the $3^{rd}$ instar stage and delayed the onset of pupariation, resulting in bigger size pupae. MKRN1 was expressed in the prothoracic gland, where the steroid hormone ecdysone is produced. Furthermore, $mkrn1^{exS}$ larvae exhibited reduced mRNA levels of phantom, which encodes ecdysone-synthesizing enzyme and E74, which is a down-stream target of ecdysone. Collectively, these results indicate that MKRN1 fine-tunes developmental timing and sexual maturation by affecting ecdysone synthesis in Drosophila. Moreover, our study supports the notion that malfunction of makorin gene family member, mkrn3 dysregulates the timing of puberty in mammals.

• Advances in nano research
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• 제14권4호
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• pp.303-312
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• 2023

In this study, the bifurcation analysis of functionally graded material is done using exponential volume fraction law. Shell theory of Love is used for vibration of shell. The Galerkin's method is applied for the formation of three equations in eigen value form. This eigen form gives the frequencies using the computer software MATLAB. The variations of natural frequencies (Hz) for Type-I and Type-II functionally graded cylindrical shells are plotted for exponential volume fraction law. The behavior of exponent of volume fraction law is seen for three different values. Moreover, the frequency variations of Type-I and -II clamped simply supported FG cylindrical shell with different positions of ring supports against the circumferential wave number are investigated. The procedure adopted here enables to study vibration for any boundary condition but for brevity, numerical results for a cylindrical shell with clamped simply supported edge condition are obtained and their analysis with regard various physical parameters is done.

• 한국광학회지
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• 제22권6호
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• pp.262-268
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• 2011

한국천문연구원이 개발한 다목적적외선영상시스템(Multi-purpose IR Imaging System, MIRIS)은 과학기술위성 3호(STSAT-3)의 주탑재체이다. 지구관측카메라(Earth Observation Camera, EOC)는 MIRIS를 구성하는 두 개의 적외선 카메라 중에 하나로, 지구의 $3{\sim}5{\mu}m$ 파장대의 적외선을 관측하기 위한 카메라이다. EOC의 광학계는 카세그레인 방식으로써 구경이 100 mm이고, 주경과 부경은 모두 비구면 반사경이다. EOC 주경의 플렉서는 링 타입으로써 발사환경에서 주경이 겪을 수 있는 충격과 진동을 견디도록 예압을 가하며 주경을 지지한다. 이는 마치 리테이너로 렌즈를 지지하는 것과 같은 메커니즘으로 주경을 지지하기 위한 시도이다. 광기계 해석을 통해 EOC 주경이 효과적으로 지지되고 있음을 확인했다.

• 박물관보존과학
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• 제24권
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• pp.1-16
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• 2020

대구 달성 고분군 중 하나인 55호분에서 발견된 부장품 중 삼엽문이자태도의 재보존처리와 제작 기법에 관한 연구이다. 이자태도는 모도가 2점, 자도가 4점이 부착된 이합도이고 출토된 완형으로는 유일하다. 과거 2회의 보존처리가 실시된 기록이 있으며 이번에 균열부 보강제 교체를 위한 재보존처리와 함께 컴퓨터 단층촬영(CT), XRF분석, 실체현미경 관찰을 통해 유물의 재질, 성분, 제작 기법을 조사하였다. 주성분은 구리(Cu)이고 금색 부분에서는 금(Au)과 수은(Hg)이 함께 검출된 것으로 보아 구리에 수은 아말감 금도금을 한 금동으로 추정된다. 제작 기법을 조사한 결과 둥근 삼엽문의 환두부와 병부의 연결은 슴베 부분을 만들어 끼웠고 병판만 금속판으로 제작되어 있는 것을 보아 장식으로서의 기능이 높다고 판단할 수 있다. 상부 자도의 결합 방식은 모도와 같고, 하부 자도는 하나의 금속판을 재단하여 만들었다. 검초는 총 2개의 판을 재단하여 만들었고 상부 자도를 검초에 고정하기 위해 자도 도신부의 아래쪽에 지지대를 넣었으며 하부 자도는 검초 일부를 재단하여 안으로 꽂아 넣었다. 표현된 문양은, 환두부는 삼엽문, 병판은 횡주 연호문, 초구금구와 초미금구는 파상형 점열문, 어미형 초미금구는 점열문을 시문하여 제작되었다.

• 한국전자통신학회논문지
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• 제7권1호
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• pp.81-89
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• 2012

범용적으로 사용되고 있는 수평형 풍력 터빈(HAWT)은 블레이드가 장착된 터빈이 회전부인 너셀에 고정되어 타워의 최상단에 지지되는 구조이다. 터빈에서 생산되는 전력은 너셀 내부에서 증속기를 통하여 발전기로 들어가게 된다. 발전기에서 생산되는 전력은 타워를 통해서 지상과 송전선으로 연결되므로 너셀의 요잉이 발생하는 경우 송전선의 꼬임이 발생하게 된다. 따라서 이를 방지하기 위한 슬립링이나 추가적인 요잉 제어 알고리즘이 필요한 단점이 있다. 제안하는 새로운 구조의 HAWT는 베벨기어와 중공축을 이용하여 송전선 문제를 해결하였다. 또한, 병렬로 접속된 두개의 발전기를 이용하여 요잉이 용이할 뿐 아니라 생산 전력을 분산시킴으로써 인버터의 용량을 줄일 수 있다. MPPT 알고리즘과 요잉 제어를 수행하는 시뮬레이션을 통해서 제안하는 구조가 풍력 발전에 효과적임을 보였다.

• 한국항행학회논문지
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• 제10권3호
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• pp.262-267
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• 2006

이동 차량에서도 멀티미디어 응용 서비스에 대한 요구가 급증함에 따라, MOST(Media Oriented Systems Transport) 프로토콜이 주목을 받게 되었다. MOST 프로토콜은 짧은 제어 메시지, 비동기 패킷, 그리고 예약형 동기 스트림 데이터와 같은 세가지 형태의 통신 모드를 지원한다. MOST는 다양한 전송모드를 지원하여 차량 내부의 네트워크에 응용하는 프로토콜로서 적합하다. 본 논문에서는 MOST 프로토콜을 장착한 AMS(Automotive Media Server) 플랫폼 기반의 임베디드 시스템을 구현하고 제어 포트와 소스포트의 동기 채널을 통한 네트워크 통신테스트를 동해 시스템을 검증한다. MOST POF(Plastic Optical Fiber) 네트워크 상에서 서로 멀티미디어 통신을 할 수 있는 프로토타입 임베디드 플랫폼을 구현하여 시스템의 동작 테스트를 위해 DivX 디코더를 연결하고 비디오 스트림과 제어 메시지를 MOST 네트워크를 통해 전송하여 동작을 확인하였다.

• 전자공학회논문지SC
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• 제47권5호
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• pp.52-61
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• 2010

최근 피부의 마찰계수를 이용하여 한의학에서의 체질을 구별하는 연구가 활발히 이루어지고 있다. 피부의 마찰계수는 여러 고문헌에서도 알려져 있듯이 태음인과 소양인의 체질을 구별하는 인자로 활용되고 있다. 본 연구에서는 다축 로드셀과 일정하중식 접촉 프로브를 이용하여 피부의 마찰계수를 정량적으로 측정하는 장비를 개발하였고 이의 측정 불확도를 측정하였다. 개발된 장비의 상대 반복도는 2 %였다. 태음인과 소양인의 체질진단 구분을 위해 왼속 손등을 측정부위로 선택하여 실험한 결과 약지를 따라 측정하는 것이 가장 효과적임을 알 수 있었다. 20명의 피험자를 대상으로 임상측정을 한 결과, 개발된 장비의 경우 3 % 이내의 측정 불확도를 가지고 태음인과 소양인의 체질 구분을 할 수 있었다.

• Journal of Korea Trade
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• 제25권5호
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• pp.58-73
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• 2021

Purpose - In the context of economic globalization and the continuous development of international trade, as countries around the sea peninsula, port construction is particularly important. Based on the research on the influencing factors of port logistics development based on the allocation analysis, QCA (Qualitative Comparative Analysis) provides the basis for the planning and policy of port logistics development and has important theoretical value and practical significance for improving the level of port logistics management, reducing logistics operating costs and increasing economic benefits. In the tide of global integration for the development of port logistics, promote the growth of foreign trade economy of the city. It is also of great significance to the development and progress of commerce and trade. Design/methodology - Based on the relevant data samples of various ports in South Korea, this paper uses fsQCA (fuzzy set Qualitative Comparative Analysis) to integrate and analyze the influence mechanism of port logistics development and extracts five influencing factors of port logistics development, including the port's scale and infrastructure in the hard environment, port-neighboring enterprises in the soft environment, hinterland economy and government support. Findings - The five factors are unable to separately constitute the necessary and sufficient conditions of port logistics development, only a combined model can influence lake port logistics development. The scale and infrastructure of the port itself and port-neighboring ring enterprises are the main core conditions, which work together on the port, affect the throughput capacity of the port, and promote the development of port logistics. When the port-neighboring enterprises are not complete and the scale is low, the growth of port throughput will be restrained and the development of port logistics will be affected, whether the hinterland economic benefits are general, the development of port-neighboring enterprises is insufficient, or the government supports are limited. Originality/value - Through the research on the development of port logistics in South Korea from the perspective of configuration, this paper finds the configuration influence of hard environment and soft environment on the development of port logistics, which has important theoretical and practical significance for better promoting the development of port logistics in South Korea.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제15권12호
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• pp.4345-4363
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• 2021

Deep Learning as a Service (DLaaS), utilizing the cloud-based deep neural network models to provide customer prediction services, has been widely deployed on mobile cloud computing (MCC). Such services raise privacy concerns since customers need to send private data to untrusted service providers. In this paper, we devote ourselves to building an efficient protocol to classify users' images using the convolutional neural network (CNN) model trained and held by the server, while keeping both parties' data secure. Most previous solutions commonly employ homomorphic encryption schemes based on Ring Learning with Errors (RLWE) hardness or two-party secure computation protocols to achieve it. However, they have limitations on large communication overheads and costs in MCC. To address this issue, we present LeHE4SCNN, a scalable privacy-preserving and communication-efficient framework for CNN-based DLaaS. Firstly, we design a novel low-expansion rate homomorphic encryption scheme with packing and unpacking methods (LeHE). It supports fast homomorphic operations such as vector-matrix multiplication and addition. Then we propose a secure prediction framework for CNN. It employs the LeHE scheme to compute linear layers while exploiting the data shuffling technique to perform non-linear operations. Finally, we implement and evaluate LeHE4SCNN with various CNN models on a real-world dataset. Experimental results demonstrate the effectiveness and superiority of the LeHE4SCNN framework in terms of response time, usage cost, and communication overhead compared to the state-of-the-art methods in the mobile cloud computing environment.

• Asian Pacific Journal of Cancer Prevention
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• 제14권5호
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• pp.3243-3254
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• 2013

It is well known that increased incidences of lung, skin, and bladder cancers are associated with occupational exposure to PAHs. Animal studies show that certain PAHs also can affect the hematopoietic and immune systems and can produce reproductive, neurologic, and developmental effects. As a consequence, several studies have been attempted to investigate the fate of PAHs in atmospheric environment during the past decades. However, there is still a lack of information in regard to the atmospheric concentration of PAHs during the "Bon Fire Night". In this study, twenty-three polycyclic aromatic hydrocarbons and twenty-eight aliphatics were identified and quantified in the $PM_{10}$ and vapour range in Birmingham ($27^{th}$ November 2001-$19^{th}$ January 2004). The measured concentrations of total particulate and vapour (P+V) PAHs were consistently higher at the BROS in both winter and summer. Arithmetic mean total (P+V) PAH concentrations were $51.04{\pm}47.62$ ng $m^{-3}$ and $22.30{\pm}19.18$ ng $m^{-3}$ at the Bristol Road Observatory Site (BROS) and Elms Road Observatory Site (EROS) respectively. In addition arithmetic mean total (P+V) B[a]P concentrations at the BROS were $0.47{\pm}0.39$ ng $m^{-3}$ which exceeded the EPAQS air quality standard of 0.25 ng $m^{-3}$. On the other hand, the arithmetic mean total (P+V) aliphatics were $81.80{\pm}69.58$ ng $m^{-3}$ and $48.00{\pm}35.38$ ng $m^{-3}$ at the BROS and EROS in that order. The lowest average of CPI and $C_{max}$ measured at the BROS supports the idea of traffic emissions being a principle source of SVOCs in an urban atmosphere. The annual trend of PAHs was investigated by using an independent t-test and oneway independent ANOVA analysis. Generally, there is no evidence of a significant decline of heavier MW PAHs from the two data sets, with only Ac, Fl, Ph, An, 2-MePh, 1+9-MePh, Fluo and B[b+j+k]F showing a statistically significant decline (p<0.05). A further attempt for statistical analysis had been conducted by dividing the data set into three groups (i.e. 2000, 2001-2002 and 2003-2004). For lighter MW compounds a significant level of decline was observed by using one-way independent ANOVA analysis. Since the annual mean of $O_3$ measured in Birmingham City Centre from 2001 to 2004 increased significantly (p<0.05), it may be possible to attribute the annul reduction of more volatile PAHs to the enhanced level of annual average $O_3$. By contrast, the heavier MW PAHs measured at the BROS did not show any significant annual reduction, implying the difficulties of 5- and 6-ring PAHs to be subject to photochemical decomposition. The deviation of SVOCs profile measured at the EROS was visually confirmed during the "Bonfire Night" festival closest to the $6^{th}$ November 2003. In this study, the atmospheric PAH concentrations were generally elevated on this day with concentrations of Fl, Ac, B[a]A, B[b+j+k]F, Ind and B[g,h,i]P being particularly high.