• Tuberculosis and Respiratory Diseases
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• v.77 no.4
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• pp.161-166
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• 2014

Since tuberculosis (TB) remains a major global health concern and the incidence of multi-drug resistant (MDR)-TB is increasing globally, new modalities for the detection of TB and drug resistant TB are needed to improve TB control. The Xpert MTB/RIF test can be a valuable new tool for early detection of TB and rifampicin resistance, with a high sensitivity and specificity. Late-generation fluoroquinolones, levofloxacin, and moxifloxacin, which are the principal drugs for the treatment of MDR-TB, show equally high efficacy and safety. Systemic steroids may reduce the overall TB mortality attributable to all forms of TB across all organ systems, although inhaled corticosteroids can increase the risk of TB development. Although fixed dose combinations were expected to reduce the risk of drug resistance and increase drug compliance, a recent meta-analysis found that they might actually increase the risk of relapse and treatment failure. Regarding treatment duration, patients with cavitation and culture positivity at 2 months of TB treatment may require more than 6 months of standard treatment. New anti-TB drugs, such as linezolid, bedaquiline, and delamanid, could improve the outcomes in drug-resistant TB. Nontuberculous mycobacterial lung disease has typical clinical and immunological phenotypes. Mycobacterial genotyping may predict disease progression, and whole genome sequencing may reveal the transmission of Mycobacterium abscessus. In refractory Mycobacterium avium complex lung disease, a moxifloxacin-containing regimen was expected to improve the treatment outcome.

• Journal of the Korea Institute of Building Construction
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• v.11 no.3
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• pp.265-275
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• 2011

As BIM is now being accepted and broadly expanded in the building industry, the demand for developing, managing, submitting, and checking the BIM models has increased. To meet this demand, it is necessary to develop and spread BIM guidelines, standards, and manuals. Meanwhile, as the number of public construction projects increases, the importance of quantifying the BIM quality checking and evaluation also grows. This study aims to enhance our understanding of the definition and characteristics of BIM quality management, and review the current situation of BIM standards worldwide. In particular, by focusing on BIM quality control and its relevant subjects, the minimum standards for BIM quality management are suggested.

• Journal of applied mathematics & informatics
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• v.29 no.5_6
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• pp.1583-1602
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• 2011

A special system of partial differential equations (PDEs) occur in a natural way while studying a class of irrotational inviscid fluid flow problems involving infinite channels. Certain aspects of solutions of such PDEs are analyzed in the context of flow problems involving multiple layers of fluids of different constant densities in a channel associated with arbitrary bottom topography. The whole analysis is divided into two parts-part A and part B. In part A the linearized theory is employed along with the standard Fourier analysis to understand such flow problems and physical quantities of interest are derived analytically. In part B, the same set of problems handled in part A are examined in the light of a weakly non-linear theory involving perturbation in terms of a small parameter and it is shown that the original problems can be cast into KdV type of nonlinear PDEs involving the bottom topography occurring in one of the coefficients of these equations. Special cases of bottom topography are worked out in detail and expressions for quantities of physical importance are derived.

• Journal of the Korea Furniture Society
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• v.28 no.4
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• pp.371-379
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• 2017

This study established the scope of the main contents and interpretation of wooden product design using the CNC manufacturing technology as well as the basic concepts of which were defined, accordingly. After coming up with the definition of the CNC wood manufacturing technology from the academic point of view, a design study, using the practical CNC manufacturing technology, was conducted by analyzing and summarizing the contents of each process. In addition, data research and analysis including review on literatures and case studies of existing products were promoted besides design development through application of the design concepts, ergonomics, principle of molding, etc. Ultimately, this study suggested the step-by-step procedure in design drawing, 3D modeling, CAD/CAM data production, CNC manufacturing, and prototype completion together with figures. Through this, the study proposed a standard manufacturing guideline for wood product design using digital manufacturing technology. Base on such efforts, the advantages and points for improvement in product design using CNC manufacturing technology and the future direction of development were forwarded. Meanwhile, a prototype image that was developed through collaborative efforts between the academic circle and field workers was presented to help the case study on the wooden product design technique using CNC.

• Economic and Environmental Geology
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• v.48 no.3
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• pp.241-246
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• 2015

Helicobacter pylori is an important transmissible human pathogen found on the luminal surface of the gastric epithelium. The organism can persist in the stomach indefinitely and causes gastroduodenal inflammation that may proceed to atrophic gastritis, peptic ulcer, gastric MALT lymphoma, and gastric cancer. Standard triple therapy which consists of proton pump inhibitor (PPI) plus two antibiotics (amoxicillin and clarithromycin) is now generally used in Korea, however, eradication rates of H. pylori has been decreasing due to increasing antibiotic resistance. In this review, current second-line treatment regimens, difficult problems on treatment, necessity of local target therapy, applicability of clay minerals as a drug delivery system (DDS), and a new therapeutic strategy and its study plans will be discussed.

• Korean Journal of Head & Neck Oncology
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• v.31 no.2
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• pp.74-77
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• 2015

A lingual thyroglossal duct cyst(LTGDC) is a rare congenital anomaly that account for only 0.5% to 2% of total thyroglossal duct cyst. LTGDC is frequently associated with respiratory problem in infants and pharyngeal foreign body sensation or dysphagia in adults. Because of its location and characteristics, lingual thyroid, dermoid cyst, and vallecular cyst should be included in differential diagnosis. Standard treatment for thyroglossal duct cyst is sistrunk's operation, but in terms of LTGDC, because of its location and cosmetic reasons, different kinds of treatments such as electrical cauterization, $CO_2$ laser, Robort surgery via transoral approach have been introduced. Recently authors encountered 21 years old woman with LTGDC and the mass was removed successfully via transoral approach using $CO_2$ laser. We report the clinical course with review of the literature.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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• v.23 no.2
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• pp.99-103
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• 2012

Spasmodic dysphonia is a chronic, focal, movement-induced, action-specific dystonia of the laryngeal musculature during speech. It can have a profound effect on quality of life, severely limiting people's communication, especially via telephone and in noisy backgrounds. Spasmodic dysphonia (SD) is usually of the adductor type characterized by glottic contractions causing tightness and voice breaks with forced-strangled voice, but it may also be abductor type or, much less commonly, mixed. Treatment options for adductor spasmodic dysphonia (ADSD) include voice therapy, surgical procedures, and botulinum toxin injections (Botox). The use of Botox injected into the laryngeal muscles remains the "gold standard" treatment for reducing the vocal symptoms of ADSD and Botox induces a temporary paresis of the laryngeal muscles and provides short-term relief of symptoms. Repeated injections of the laryngeal muscles, generally every 3-4 months, are required for continuous relief of symptoms. Improvement in vocal function has been reported after use of Botox injections, though a completely normal voice is rarely achieved. In this hospital, 1,030 patients have been enrolled for Botox injection therapy so far (May, 2012). In this review article, I'd like to present my personal experience of management of spasmodic dysphonia mainly by Botox injection.

• Korean Journal of Acupuncture
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• v.29 no.2
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• pp.250-259
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• 2012

Objectives : In this study, it has aimed to search cupping therapy standardization research course by reviewing former studies. Methods : It has reviewed articles about cupping therapy, published in South Korea. Review focused on cupping therapy treating methods. Results : Articles about cupping therapy is slightly increasing. Clinical study was the most popular study method. It has most used non-bleeding cupping therapy, and bleeding cupping therapy is next. Treating time was very various and there were no tendency or trends about treating time. Pressure inside cup has used from 30 mmHg to 600 mmHg, and pressure of 600 mmHg used mostly. Conclusions : As a result of this study, it is considered that data and standard about pressure and treating time is required. And it should be focus on pressure and treating time to standardizing cupping therapy.

• School Mathematics
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• v.6 no.1
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• pp.37-57
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• 2004

The purpose of this study is to review, through case study, how the use of web materials has influence on the improvement of self-oriented Learning in mathematics of primary school. This is one of the ways to improve classroom lectures suggested in the 7th National Standard of Curriculum. To accomplish this, the following three studies were conducted. First, a questionnaire concerning the improvement of self-oriented Learning Skill through the use of the materials on the web was designed and analyzed. Second, the activities of the class using the web materials were recorded and the study activities of the children were observed. Third, the process of writing notes about their study using web materials was analyzed though interviews after teaching and learning. Through these studies, it has been shown how web materials contribute to the improvement of self-oriented Learning Skill.

• Archives of Plastic Surgery
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• v.43 no.1
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• pp.3-9
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• 2016

The reconstruction of the mandible is a complex procedure because various cosmetic as well as functional challenges must be addressed, including mastication and oral competence. Many surgical techniques have been described to address these challenges, including non-vascularized bone grafts, vascularized bone grafts, and approaches related to tissue engineering. This review summarizes different modifications of the free vascularized fibula graft, which, since its introduction by Hidalgo in 1989, has become the first option for mandibular reconstruction. The fibula free flap can undergo various modifications according to the individual requirements of a particular reconstruction. Osteocutaneous flaps can be harvested for reconstruction of composite defects. 'Double-barreling' of the fibula can, for instance, enable enhanced aesthetic and functional results, as well as immediate one-stage osseointegrated dental implantation. Recently described preoperative virtual surgery planning to facilitate neomandible remodeling could guarantee good results. To conclude, the free fibula bone graft can currently be regarded as the "gold standard" for mandibular reconstruction in case of composite (inside and outside) oral cavity defects as well as a way of enabling the performance of one-stage dental implantation.