• Clinics in Shoulder and Elbow
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• 제26권2호
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• pp.191-204
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• 2023

Avascular necrosis (AVN) of the humeral head is a rare, yet detrimental complication. Left untreated, humeral head AVN frequently progresses to subchondral fracturing and articular collapse. Cases of late-stage humeral head AVN commonly require invasive procedures including humeral head resurfacing, hemiarthroplasty, and total shoulder arthroplasty (TSA) to improve clinical outcomes. However, in cases of early-stage AVN, core decompression of the humeral head is a viable and efficacious short-term treatment option for patients with pre-collapse AVN of the humeral head to improve clinical outcomes and prevent disease progression. Several techniques have been described, however, a percutaneous, arthroscopic-assisted technique may allow for accurate staging and concomitant treatment of intraarticular pathology during surgery, although further long-term clinical studies are necessary to assess its overall outcomes compared with standard techniques. Biologic adjunctive treatments, including synthetic bone grafting, autologous mesenchymal stem cell/bone marrow grafts, and bone allografts are viable options for reducing the progression of AVN to further collapse in the short term, although long-term follow-up with sufficient study power is lacking in current clinical studies. Further long-term outcome studies are required to determine the longevity of core decompression as a conservative measure for early-stage AVN of the humeral head.

• 대한방사성의약품학회지
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• 제6권2호
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• pp.155-164
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• 2020

Polyethylene glycol (PEG) has been the most commonly used polymer for the past few decades in the field of biomedical applications due to its gold standard stealth effect. PEGylation of antibody-drug conjugates, liposomes, peptides, nanoparticles, and proteins is done to improve their pharmaceutical efficacy and pharmacokinetic properties. PEGylation of antibodies with various PEG linkers improves targeting ability by increasing the blood circulation time and thus enhances the biodistribution profiles. It also assists in minimizing the immediate capture by the reticuloendothelial system. In this review, we summarize the effect of PEG linkers in an antibody conjugation and their pharmacokinetics in the field of biomedical imaging.

• 자원ㆍ환경경제연구
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• 제31권4호
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• pp.505-529
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• 2022

라돈은 폐암사망 위험을 일으키는 방사성 가스이다. 본 논문은 조건부가치측정법(CVM)을 이용하여 우리나라 주택에서의 라돈 노출로 인한 사망자의 통계적 생명가치(VSL)를 20억 5,373만 원으로 추정하였다. 2020년의 경우, 주택 라돈으로 인한 사망자 수는 2,330명, 그 사회적 비용은 4조 7,836억 원으로 추정하였다. 주택에 대한 국가 라돈 농도 규제기준을 200Bq/m³로 설정하면 691명의 사망자 수가 감소하여 1조 4,191억 원의 사회적 편익이 발생하는 것으로 나타났다. 본 논문은 주택 라돈 노출의 원천과 특징 및 건강위해성(health risk)을 상세히 논하고 주택 라돈 저감을 위한 정책 예산의 획기적인 증액이 중요함을 강조하였다.

• 한국의상디자인학회지
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• 제24권4호
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• pp.135-152
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• 2022

Recent weddings have been performed in more unique and characterful styles going beyond the existing same old method of past weddings, and they are changed into small weddings with simplified style without unnecessary procedures by choosing a wedding venue different from others. It is necessary to develop a new wedding dress design suitable for such changing wedding culture, and especially, dresses are required to have some practical designs, so that they can be worn not only for the wedding ceremony or party but also for everyday life. Therefore, the purpose of this study is to develop a new normal wedding dress for small weddings that reflect design according to the emerging small wedding culture. To this end, a theoretical review of small weddings was conducted, and based on this, a new normal wedding dress design was developed for small weddings. Based on practicality and economic feasibility, the New Normal Wedding Dress exhibited 'variable by wearing method' that changes according to the wearer's purpose and 'variable by attaching and detaching method' that changes according to the detachment of details. The small wedding dress developed through this study is expected to become a new standard for wedding dresses that is suitable for the changing wedding culture.

• 무역학회지
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• 제42권2호
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• pp.97-116
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• 2017

한국과 베트남은 1992년 국교를 정상화한 이후 통상관계가 괄목할만 성장을 하여 한국은 베트남에서 외국인투자 1위 국가가 되었다. 베트남은 WTO 가입 등을 통해 통상관련 제도 등을 선진화하면서 국제통상에서 가장 각광받는 나라중에 하나이다. 베트남은 한국의 대아세안 통상정책에서 중요한 통상파트너이다. 또한 베트남의 미국, 중국, 일본과의 통상관계는 한국의 통상정책에 지대한 영향을 미치고 있다. 본연구는 베트남의 통상정책을 경제적인 접근뿐만 아니라 정치적, 국제관계적인 접근을 통하여 분석하여 한국과 베트남의 통상증진의 방안을 미시적인 양국의 통상관계 뿐만 아니라 다자간 통상협의체의 관점과 미중일의 삼국간의 관점에서 거시적으로도 분석하고자 한다.

• Geomechanics and Engineering
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• 제33권5호
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• pp.453-462
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• 2023

Intermediate Geomaterials (IGMs) are natural formation materials that exhibit the engineering behavior (strength and compressibility) between soils and rocks. The engineering behavior of such material is highly unpredictable as the IGMs are stiffer than soils and weaker/softer than rocks. Further, the characterization of such material needs exposure to both soil and rock mechanics. In most conventional designs of geotechnical structures, the engineering properties of the IGMs are either aligned with soils or rocks, and this assumption may end up either in an over-conservative design or under-conservative design. Hence, many researchers have attempted to evaluate its actual engineering properties through laboratory tests. However, the test results are partially reliable due to the poor core recovery of IGMs and the possible sample disturbance. Subsequently, in-situ tests have been used in recent years to evaluate the engineering properties of IGMs. However, the respective in-situ test finds its limitations while exploring IGMs with different geological formations at deeper depths with the constraints of sampling. Standard Penetration Test (SPT) is the strength-based index test that is often used to explore IGMs. Moreover, it was also observed that the coefficient of variation of the design parameters (which represents the uncertainties in the design parameters) of IGMs is relatively high, and also the studies on the probabilistic characterization of IGMs are limited compared with soils and rocks. With this perspective, the present article reviews the laboratory and in-situ tests used to characterize the IGMs and explores the shear strength variation based on their geological origin.

• 산경연구논집
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• 제14권1호
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• pp.1-11
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• 2023

Purpose: The purpose of the current research is to investigate the contribution of the sports and leisure sector to raising elderly citizens' quality of life. Through this investigation, the sport and leisure sector may give seniors a sense of safety and security by creating a safe atmosphere in which they can engage in activities and feel a part of their communities. Research design, data and methodology: Literature data were extracted from previous studies between the role of the sports leisure sector and living quality for senior citizens using a standardized data extraction form by two independent reviewers after articles have been included in the review. Each study's data extraction includes details on the study's design, exposure, outcome metrics, and findings. Results: Based on the qualitative textual approach, the present author had figured out total four Functions assumed as follows: (A) Physical Activity and Exercise, (B) Socialization and Interaction, (C) Opportunities for Learning and Development, and (4) Emotional Wellbeing. Conclusions: All in all, professionals should try to give elders chances for social interaction and peer participation in order to foster a feeling of community and belonging. This might entail setting up groups or leagues for elders to engage in meaningful social activities, like hiking or sports.

• 동남아시아연구
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• 제22권1호
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• pp.207-245
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• 2012

With rapid industrialization and urbanization, numerous cities are faced with urban slum phenomenon combined with housing shortage fueled by population explosion. In Kuala Lumpur, the capital city of Malaysia, the government hereby embarked on supply of public housing to resolve such pending issue. This study aims to understand the periodic changes of public housing as a common basis for basic housing policies with analysis specific features of site plan, block layout, and unit plans. For this purposes, the filed survey during January, 2011 were proceeded. We hereby visited and surveyed a total of 40 apartment complexes for the 1970s~the 2000s (10 complexes respectively on a decade basis). Consequently, Malaysian public apartments prove to offer a very uniform pattern based upon standard plans. Their early plans aren't fairly distincted from those of other countries, but their layouts of plan become differentiated compared with other nations as they actively apply a ventilator called 'air well' in response to tropical climate amid the change of times. This study is expected to broaden our understanding of Malaysia's unique housing culture and lifestyle.

• Journal of Digestive Cancer Research
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• 제5권1호
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• pp.37-43
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• 2017

Laparoscopic cholecystectomy is of one the most common general surgical operations performed today. Concomitant choledocholithiasis occurs in roughly 10-20% of patients with symptomatic gallstones. Laparoscopic bile duct exploration (LBDE) offers a single-stage minimally-invasive solution to the management of choledocholithiasis. LBDE may be performed either via the transcystic route or via laparoscopic choledochotomy. A number of strategies to improve success are available to the surgeon to help in the problem of complicated choledocholithiasis, these range from simple maneuvers to the use of laser or mechanical lithotriptors. With the advances in laparoscopic surgery, it is also possible to handle complex surgical conditions such as Mirizzi syndrome or recurrent pyogenic cholangitis laparoscopically, even though these have yet to be accepted as standard of care. Following laparoscopic choledochotomy, options for closure include: primary closure, closure over a T-tube, and closure over an endobiliary stent. T-tube placement has been associated with increased operating time and hospital length of stay compared to primary closure, with no significant differences in morbidity. Based on the available literature, LBDE appears comparable to ERCP with regards to procedural efficacy and morbidity. LBDE remains relevant to the general surgeon and is best viewed as being complementary to endoscopic therapy in the management of choledocholithiasis.

• Journal of Trauma and Injury
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• 제36권3호
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• pp.165-171
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• 2023

Trauma remains a significant healthcare burden, causing over five million yearly fatalities. Notably, the liver is a frequently injured solid organ in abdominal trauma, especially in patients under 40 years. It becomes even more critical given that uncontrolled hemorrhage linked to liver trauma can have mortality rates ranging from 10% to 50%. Liver injuries, mainly resulting from blunt trauma such as motor vehicle accidents, are traditionally classified using the American Association for the Surgery of Trauma grading scale. However, recent developments have introduced the World Society of Emergency Surgery classification, which considers the patient's physiological status. The diagnostic approach often involves multiphase computed tomography (CT). Still, newer methods like split-bolus single-pass CT and contrast-enhanced ultrasound (CEUS) aim to reduce radiation exposure. Concerning management, nonoperative strategies have emerged as the gold standard, especially for hemodynamically stable patients. Incorporating angiography with embolization has also been beneficial, with success rates reported between 80% and 97%. However, it is essential to identify the specific source of bleeding for effective embolization. Given the severity of liver trauma and its potential complications, innovations in diagnostic and therapeutic approaches have been pivotal. While CT remains a primary diagnostic tool, methods like CEUS offer safer alternatives. Moreover, nonoperative management, especially when combined with angiography and embolization, has demonstrated notable success. Still, the healthcare community must remain vigilant to complications and continuously seek improvements in trauma care.