• 대한방사선기술학회지:방사선기술과학
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• 제39권2호
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• pp.149-156
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• 2016

자기공명영상을 이용한 심장혈류의 측정은 호흡과 심장의 불수의적인 움직임으로 인해 제한되어 왔다. 따라서 본 연구에서는 심장혈류의 측정값을 비교하여 적절한 호흡방법과 영상변수를 제시하고 위상대조도 자기공명영상을 통한 심장혈류검사의 정확성을 향상시키고자 하였다. 연구 대상자는 정상의 지원자 15명(남: 10명, 여: 5명) 평균연령: $30{\pm}5.2$세를 대상으로 하였다. 상행대동맥과 하행대동맥에서 위상대조도 자기공명영상을 이용하여 각각 호흡정지 retrospective 1NEX와 비 호흡정지 retrospective 1-3NEX로 검사하여 비교하여 평가하였다. 연구 결과 상행대동맥에서 호흡정지 retrospective 1NEX의 평균혈류량/평균혈류속도는 각각 $96.17{\pm}19.12ml/sec$, $17.04{\pm}4.12cm/sec$로 비 호흡정지 retrospective 1NEX의 $72.31{\pm}13.27ml$, $12.32{\pm}3.85cm/sec$와는 통계적으로 유의한 차이를 보였다(p<0.05). 반면에 2NEX에서는 평균혈류량과 평균혈류속도가 $101.90{\pm}24.09$, 16.84{\pm}4.32, 3NEX에서는 $103.06{\pm}25.49$, $16.88{\pm}4.19$로 통계적으로 유의한 차이를 보이지 않았다(p>0.05). 하행대동맥에서 호흡정지 retrospective 1NEX의 평균혈류량/평균혈류속도는 $76.68{\pm}19.72ml/sec$, $22.23{\pm}4.8cm/sec$로 비 호흡정지 retrospective 1-3NEX와 비교 시 유의한 차이를 보이지 않았다. 그러므로 비 호흡정지 retrospective방법은 NEX의 증가에 따라 호흡정지 retrospective방법과 비교하여 심장혈류 측정값에 유의한 차이점이 없기 때문에 숨을 잘 참지 못하거나 또는 소아환자에게 있어서 심장혈류 검사의 진단적 가치를 높여줄 것으로 사료된다.

• 대한수의학회지
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• 제37권4호
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• pp.809-816
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• 1997

In this presented study, we established a method for diagnosis of porcine epidemic diarrhea(PED) by in situ hybridization(ISH), which made distinct progress in diagnostic pathology. We also carried out the retrospective diagnosis through ISH to assume the exact time of the first outbreak and incidence of PED in Korea. The outbreak of PED in Korea reported in 1992. However, since the end of 1980's, some researches of pig-industry have already suspected the outbreak of PED, not transmissible gastroenteritis(TGE). In this experiment, we performed the ISH using 80 formalin-fixed and paraffin-embedded tissues of porcine intestine which were requests for pathological diagnosis from 63 farms whose primary sign was diarrhea from 1984 to 1991. We prepared biotinylated cDNA probe(492base pairs) for ISH by nick translation method and carried out the ISH, using $Microprobe^{TM}$ capillary action system(Fisher $Biotech^R$). We detected PED virus in intestinal mucosa of 2 cases in 1992, 1 case in 1988, and 1 case in 1987. As a result, we assume that the outbreak of PED in Korea have already started since 1987.

• Journal of Chest Surgery
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• 제57권5호
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• pp.458-459
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• 2024

• 대한의용생체공학회:의공학회지
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• 제42권4호
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• pp.175-185
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• 2021

Purpose: Vital sign are used to help assess the general physical health of a person, give clues to possible diseases, and show progress toward recovery. Researchers are using vital sign data and AI(artificial intelligence) to manage a variety of diseases and predict mortality. In order to analyze vital sign data using AI, it is important to select and extract vital sign data suitable for research purposes. Methods: We developed a method to visualize vital sign and early warning scores by processing retrospective vital sign data collected from EMR(electronic medical records) and patient monitoring devices. The vital sign data used for development were obtained using the open EMR big data MIMIC-III and the wearable patient monitoring device(CareTaker). Data processing and visualization were developed using Python. We used the development results with machine learning to process the prediction of mortality in ICU patients. Results: We calculated NEWS(National Early Warning Score) to understand the patient's condition. Vital sign data with different measurement times and frequencies were sampled at equal time intervals, and missing data were interpolated to reconstruct data. The normal and abnormal states of vital sign were visualized as color-coded graphs. Mortality prediction result with processed data and machine learning was AUC of 0.892. Conclusion: This visualization method will help researchers to easily understand a patient's vital sign status over time and extract the necessary data.

• Journal of the Korean Data and Information Science Society
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• 제26권6호
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• pp.1317-1325
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• 2015

두 집단간을 비교하는 다양한 임상연구에서 수집된 데이터를 분석할 때 질환에 미치는 영향을 알아보는 방법으로는 현 시점에서 어떤 특정 질환을 일으킬 수 있는 위험요인포함 우, 무에 띠라 연구대상자를 나누어, 추적 관찰하는 전향적 임상연구에서의 분석과 현 시점에서 질환 유, 무에 따라 위험요인을 과거의 연구대상자의 관찰기록을 바탕으로 확인하는 후향적 임상연구에서의 분석이 있다. 접근 방법과 연구 설계는 다르지만 두 가지 연구의 목적은 두 집단 간 명확한 차이를 확인하는데 있으며, 나아가 두집단의 분류에 영향을 주는 변수가 무엇인지를 알아보는 방법이다. 특히 임상연구에서 두 집단을 비교할 때 성별과 나이와 같은 기본적 특성변수의 영향을 통제한 상태에서 임상적 변수들의 집단 간 차이와 영향을 살펴보아야 한다. 하지만 후향적 연구에서는 과거의 관찰기록을 바탕으로 분석이 진행되는 연구이므로 연구대상자를 두 집단으로 무작위 할당하지 못했기 때문에 기본적인 특성변수들이 차이가 나는 경우가 빈번하게 발생할 수 있다. 이를 해결하기 위하여 임상자료를 분석하는 방법으로 공변량을 사용한다. 대표적으로 공변량을 사용하는 분석방법으로는 공분산분석, 수정회귀모형, propensity score matching 방법 등이 있다. 본 연구는 후향적 임상연구에서 공변량을 이용한 자료 분석 방법 및 propensity score matching 방법을 소개하고, 실제 위암 환자들의 재발관련 자료에 적용하여, 그 필요성을 확인한다.

• 대한치과보철학회지
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• 제45권1호
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• pp.48-59
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• 2007

Statement of problems: There are few studies which reported the survival rates of the specific dental implant systems in the Korean population with the follow-up periods longer than 5 years. Purpose: This retrospective clinical study was aimed to evaluate cumulative survival rate (CSR) of $Br{\aa}nemark$ implants followed for 10 years and to determine risk factors for implant failure. Material and methods: A total of 271 $Br{\aa}nemark$ implants in 83 patients were investigated with several identified risk factors. Life table analysis was undertaken to examine the CSR. Cox regression method was conducted to assess the association between potential risk factors and overall CSR. Results: Thirty implants failed. The 10-year implant CSR was 82.5%. Cox regression analysis demonstrated a significant predictive association between overall CSR and implant length (P<.05). Conclusion: An acceptable long-term result of $Br{\aa}nemark$ implant was achieved and implant length showed a significant association with the CSR.

• 정신신체의학
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• 제4권2호
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• pp.198-206
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• 1996

To assess premenstrual changes in adolescents, a self rating retrospective premenstrual assessment from(PAF) and a prospective daily rating form(DRF) were administered to 230 high school students who reported premenstrual changes. The results were as follows 1) According to typological categories of retrospective premenstrual assessment form, the most commonly reported changes in mood and behavior were major depressive syndrome(40.0%), impulsive syndrome(20.9%). Especially among the subtype of depressive syndrome, hostility feature and withdrawal feature were most frequent. The most commonly reported changes in physical condition were general discomfort(73.5%), fatigue(33.9%). 50.9% of all subjects reported impaired social function. 2) 41.2% of the subjects who met the criteria for typological categories of retrospective premenstrual assessment form were confirmed by prospective daily rating form. 3) According to different criteria of percent change method of assessing symptom change, 38.7% of all subjects had at least one mild premenstrual change and 23.5% had at least one moderate premenstrual change. 4) Using prospective daily rating form, overall psychological changes were confirmed more frequently than physical changes. Of the mild premenstrual changes, 'low energy, tired & weak', 'less or impaired work' were most common changes. Of the moderate premenstrual changes, the most common change was 'low energy, tired & weak'. 5) As attitude toward menstruation, 44.9% of the subjects with confirmed premenstrual changes had more negative attitude(disgusted) toward menstruation. 6) The subjects with confirmed mild or moderate premenstrual changes had only dysphoric mood changes or both physical and dysphoric mood changes, but did not have only physical changes. These results suggest that retrospective reports of premenstrual changes were partially confirmed by daily prospective ratings. A substantial number of adolescents appeared to experience premenstrual changes, and the most common confimed premenstrual change of mild or moderate severity was 'low energy, tired and weak'.

• 대한한방소아과학회지
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• 제19권2호
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• pp.243-253
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• 2005

Objective : In this study we aimed to· investigate the parental recognition on Herbal Medication. The result showed that parents concerned about the effect of Herbal Medication on liver function and gaining weight. Therefore, we had a retrospective study on the effect of Herbal Medicaion on liver function and gaining weight. Method : In parent's recognition study, we surveyed 354 parents of children who make a first visit to Department of Oriental Pediatrics in ${\bigcirc}{\bigcirc}$ Medical Center from 3 October to 2 November 2005. In retrospective study, we examined medical record of 22 children who visited to Department of Oriental Pediatrics in Kyunghee Medical Center from 30 September 2005 to 1 January 2005. Height, weight, BMI, body fat mass, body fat ratio, AST and ALT were estimated at two points; before and after Herbal Medicaion treatment. Result: The mean of expectation of parents on the efficacy of Herbal Medication was 75.14 on the VAS scale, which was interpreted as significantly high. The result showed the effect of Herbal Medicaion on liver function(48%) and gaining weight(53%) took the largest portion. When we observe the effect of Herbal Medication on Liver function, after Herbal Medication treatment we have slightly increased AST and slightly decreased ALT, but they were not statistically significant. Also we observe the effect of Herbal Medication on getting obesity after Herbal Medication treatment. The result showed that we have slightly decreased BMI, body fat mass, body fat ratio, but they were not statistical1y significant. Conclusion : Our report shows parents of children have high expectation and stand favorable on the efficacy of the Herbal Medication. We found that parents concerned the most about the effect of Herbal Medicaion on liver function and gaining weight. Our retrospective study showed that Herbal Medicaion treatment on children has relationship with neither liver function nor the degree of obesity.

• 한국의료질향상학회지
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• 제6권1_2호
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• pp.80-91
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• 1999

Background : With the CQI concepts, which emphasize doing the right things right the first time, we tried to enhance the timely completion of medical records by changing the review process from retrospective method to concurrent one. Methods : Against the current retrospective QA activity, Medical record administrator did the concurrent QA of the inpatient medical records with the deficiency sheets. One general surgery ward was chosen as a trial one. The deficiency rate of the medical records of the discharged patients was compared before and after the enforcement of the system. Job analysis of the medical record departments was done about four tertiary care hospitals located in Seoul to estimate the cost and the time consumed by current system. Results : There was a little improvement in the completion rate of the medical records after the trial. The new system was effective. And job analysis showed that much money and time were wasted by current retrospective feedback system. Conclusion : Though the result was not so satisfactory, it should be considered that this test was a voluntary one and the interns and residents were not forced to complete the medical records during this trial period. If there be any strong motivation to complete the medical record in time, this system is sure to be succeed. As the DRG system requires the concurrent review of the medical records to confirm severity of the patient's illness and to assure the timely discharge, it is desirable to enforce this method with the DRG system together. DRG coding and reducing deficiency rate of the medical records can be accomplished simultaneously.

• 한국중재학회지:중재연구
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• 제32권4호
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• pp.103-141
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• 2022

Traditionally, schedule analysis in Korea has been used, mainly through the Critical Path Method, to evaluate the claim for extension of time and/or the amount of liquidated damages for delay. Critical path method, however, cannot identify the delay event and its impact occurred in non-critical path especially in multi facility projects. In multi facility projects that comprise several independent but related facilities or structures, each facility has its own facility critical path the duration of which will be impacted by facility specific critical delays. Thus, only through the non-critical delay analysis along with the critical delay analysis damages not attributable to contractors may be remedied in full. Because all the records and pictures can reveal what has actually happened in post contract review, only the retrospective analysis rather than the prospective analysis based on the assumptions can establish the cause and allocate the each parties' responsibilities appropriately.