• Title/Summary/Keyword: retardation also

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A Case of Cockayne Syndrome with Focal Segmental Glomerulosclerosis (국소성 분절성 사구체 경화증(FSGS)을 동반한 Cockayne 증후군 1례)

  • Shin, Hye-Kyung;Kim, Gun-Ha;Yim, Hyung-Eun;Hong, Young-Sook;Lee, Joo-Won;Won, Nam-Hee;Yoo, Kee-Hwan
    • Childhood Kidney Diseases
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    • v.11 no.1
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    • pp.100-105
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    • 2007
  • Cockayne syndrome is a rare autosomal recessive disorder characterized by cachectic dwafism, mental retardation, loss of facial subcutaneous adipose tissue, microcephaly and photosensitive dermatitis. It is associated with renal abnormalities characterized by hyalinization of glomeruli, atrophy of tubules and interstitial fibrosis. To our knowledge, this is the first report of a case of Cockayne syndrome with FSGS in Korea. A 7-year old boy was admitted for evaluation of hypertension and proteinuria, which were detected 2 month ago. He was followed for short stature(<3 percentile), mental retardation(IQ 55), strabismus and dental caries since 3 years ago. He also showed microcephaly, a bird-like face and relatively large hands and feet. Laboratory findings showed decreased creatinine clearance($C_{Cr}$ 76.1 mL/min/$1.73m^2$) and proteinuria(1,548 mg/day). Renal biopsy demonstrated focal segmental glomerulosclerosis of the hilar type with large hyaline deposits, moderate tubular atrophy and interstitial fibrosis. His cardinal features, mental retardation, and renal biopsy findings were consistent with Cockayne syndrome. We report here a very rare case of Cockayne syndrome with FSGS presenting with proteinuria and hypertension.

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About the Necessity for Development of Autonomous Mobility Device for Children with Severe Developmental Retardation

  • Matsuo, Kiyomi;Murata, Tomoyuki;Koga, Takanori;Kubo, Atsuko;Yoshida, Yuichi;Karakawa, Yosuke;Kawaguchi, Hiroshi;Tanaka, Toru;Masaki, Jun;Taketomi, Toshikatsu;Kitajima, Takeo
    • Journal of rehabilitation welfare engineering & assistive technology
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    • v.2 no.1
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    • pp.1-4
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    • 2009
  • In this paper, I will report the cases of children who are able to study at kindergarten or elementary school because they learned how to move by themselves using a moving aid before school age, and I will also discuss the development of a mobility device which allows severely disabled preschoolers to practice moving around by themselves safely and easily at home and institutions.

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Electro-optic Characteristics of the fringe-field Driven Reflective Hybrid Aligned Nematic Liquid Crystal Cell using a Liquid Crystal with Positive Dielectric Anisotropy (유전율 이방성이 양인 액정을 이용한 fringe-Field 구동형 반사형 Hybrid Aligned Nematic 액정 디스플레이의 전기-광학 특성)

  • Song, Je-Hoon;Choi, Min-Oh;Lim, Young-Jin;Lee, Seung-Hee
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.18 no.8
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    • pp.724-728
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    • 2005
  • Electro-optic characteristics of reflective hybrid aligned liquid crystal (LC) cell driven by fringe field using a nematic LC with positive dielectric anisotropy have been studied. Optimized optical configurations are achieved by using a single polarizer, half-wave film and a cell with quarter-wave retardation. The simulation results shows an optimum cell retardation of $0.30{\mu}m$. This value may allow a practical cell gap larger than $3{\mu}m$, which makes it easy to control in the manufacturing process. Furthermore, this LC cell with optimized cell parameters shows low wavelength dispersion and the contrast ratio greater than 5 over exists about $100{\circ}$ in vertical direction and $160{\circ}$ in horizontal direction. Also, when using the LC with positive dielectric anisotropy rather than negative dielectric anisotropy, the display shows low power consumption and fast response time.

The Efficiency of Intelligence Quotient Test at Prevention of Mental Retardation and Dementia (신경퇴화 및 지적장애 예방에 관한 고지능검사도구 이용의 실효성 연구)

  • Yeom, Seung-Min;Jeon, Sang-Hoon;Yi, Min-Kee;Kim, Da-Eun;Yang, Dae-Wook
    • The Korean Journal of Health Service Management
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    • v.7 no.2
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    • pp.101-111
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    • 2013
  • To develop the Korean-Version-Improvement program for ordinary people, we investigate how Korean-High-Intelligent people use their cognitive function, intellectual capacity and Intelligent Quotient test. Using Mensa iq test, we classify intelligent examination tool into various components; visual, geometrical component and cognitive interpretation component. Also we organized each component, got database of intelligent subjects sample, classified itemized availability. Based on these things, we prove efficiency of intelligent examination tool. We found out that high intelligent people showed high Intelligent Index using visual cognitive stimulation with cognitive function when subjects were exposed to certain situation; solving the problem. This intelligent examination tool is low price and safe and easily carrying out with personal computer. If we develop intelligence quotient examination customized with mental retardation populations, a variety of subjects will improve their cognition with efficiency and inexpensively.

Motor delay : cerebral palsy (운동발달 장애)

  • Park, Ho Jin
    • Clinical and Experimental Pediatrics
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    • v.49 no.10
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    • pp.1019-1025
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    • 2006
  • Motor delay, when present, is usually the first concern brought by the parents of children with developmental delay. Cerebral palsy that is the most common motor delay, is a nonspecific, descriptive term pertaining to disordered motor function that is evident in early infancy and is characterized by changes in muscle tone, muscle weakness, involuntary movements, ataxia, or a combination of these abnormalities. A wide range of causative disorders and risk factors have been identified for cerebral palsy, and broadly classified into 5 groups; perinatal brain injury, brain injury related to prematurity, developmental abnormalities, prenatal risk factors, and postnatal brain injury. Delay in attaining developmental milestones is the most distinctive presenting complaint in children with cerebral palsy. A detailed history and thorough physical and neurologic examinations are crucial in the diagnostic process. The clinician should be cautious about diagnostic pronouncement unless the findings are unequivocal. Several serial examinations and history review are necessary. All children with cerebral palsy should undergo a neuroimaging study, preferably MRI, because an abnormality is documented on head MRI(89%) and CT(77%). The high incidence rates for mental retardation, epilepsy, ophthalmologic defects, speech and language disorders and hearing impairment make it imperative that all children with cerebral palsy be screened for mental retardation, ophthalmologic and hearing impairments, and speech and language disorders; nutrition, growth, and swallowing also should be closely monitored.

A Study for Satisfaction and Expectation of Effect on the Growth of Children Treated with Herbal Medicine (소아 성장을 위한 한약투여에 대한 만족도와 기대치 조사)

  • Park, Eun-Seong;Lee, Jin-Young;Kim, Deog-Gon
    • The Journal of Pediatrics of Korean Medicine
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    • v.24 no.1
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    • pp.36-45
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    • 2010
  • Objectives The purpose of this study is to evaluate the effect of herbal medicine in children's growth and to report the children's expectation. Methods 171 children visited the department of Pediatrics, Kyung-Hee Oriental Medical Hospital from June 2009 to December 2009 were studied. They were treated more than 6 months and they visited our clinic more than 3 times. Every time when patients visited our hospital, their height, body weight and obesity degree was examined using DS-102(dszenix, Seoul). Also, height percentile of first and the last visit was measured, and those were compared by the Growth Statistics Curve made by the Korean Association of Pediatrics, 2007. Results and Conclusions The mean growth of total children increased by 4.42 percent; the increased percent for boys was 4.17 and that of girls was 5.00. Herbal medical treatment helped growth in children who took medicine for growth retardation problem. Plus, majority of parents who visited the department of Pediatrics, Oriental Medical Hospital satisfied with the service and their children's height. Although thinking genetic factor is important for their height, but they think that herbal medical treatment help the growth with changing eating habit.

Effect of Addition of Potato peel , Guar gum , Polydextrose on Quality of Backsulgies (감자 껍질 , Guar gum 및 Polydextrose 첨가에 의한 백설기의 품질특성 변화)

  • Choi, Young-Seon;Kim, Young-A
    • Korean journal of food and cookery science
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    • v.8 no.3
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    • pp.333-341
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    • 1992
  • The physicochemical, rheological and sensory characteristics of 'BACKSULGIES', which was added with potato peel, guar gum or polydextrose, were investigated. The maximum acceptable addition ratio of dietary fiber to 'BACKSULGI' was 10%. And optimal addition ratio was 3% for all samples. The water binding capacity was affected by dietary fiber sources and incubation conditions (temperature and time). The Guar gum had me highest value of water binding capacity. The solubility was highly related with water binding capacity and me swelling power was increased with temperature increment. The degree of gelatinization was not significantly different with dietary fiber sources. But me values of gelatinization of 'BACKSULGIES' added with dietary fibers were significantly higher than mose of 'BACKSULGI' with no dietary fiber. Generally hardness and brittleness incresed along with storage time. But me hardness of 'BACKSULGIES' added with dietary fibers was significantly lower man those of 'BACKSULGI' with no dietary fiber. The retardation effect of dietary fibers for retrogradation of 'BACKSULGIES' was also proved by time constant determination of Avrami equation. Sernsory evaluation revealed that me addition of dietary fibers did not reduce the organoreptic quality. Therefore potato peel 3%, guar gum 3%, polydextrose 3% were optimum addition ratio which could be accepted as conventional 'BACKSULGI'. As me results of this study, it was proved mat the additions of dietary fibers to 'BACKSULGI' had the retardation effect of retrogradation.

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A Stacked Polusilicon Structure by Nitridation in N2 Atmosphere for Nano-scale CMOSFETs (나노 CMOS 소자 적용을 위한 질소 분위기에서 형성된 질화막을 이용한 폴리실리콘 적층 구조)

  • Ho, Won-Joon;Lee, Hi-Deok
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.18 no.11
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    • pp.1001-1006
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    • 2005
  • A new fabrication method is proposed to form the stacked polysilicon gate by nitridation in $N_2$ atmosphere using conventional LP-CVD system. Two step stacked layers with an amorphous layer on top of a polycrystalline layer as well as three step stacked layers with polycrystalline films were fabricated using the proposed method. SIMS profile showed that the proposed method would successfully create the nitrogen-rich layers between the stacked polysilicon layers, thus resulting in effective retardation of dopant diffusion. It was observed that the dopants in stacked films were piled-up at the interface. TEM image also showed clear distinction of stacked layers, their plane grain size and grain mismatch at interface layers. Therefore, the number of stacked polysilicon layers with different crystalline structures, interface position and crystal phase can be easily controlled to improve the device performance and reliability without any negative effects in nano-scale CMOSFETs.

SOME OBSERVATIONS ON THE MECHANISM OF CURE RETARDATION

  • Son, P.N.
    • Elastomers and Composites
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    • v.13 no.4
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    • pp.277-281
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    • 1978
  • 1. A good retarder reacts fast with MBT and. forms a non-scorchy accelerator. 2. The decrease in cure rate$(k_1)$ is attributable to the slow cure rate of 2-cyclohexyldithiobenzothiazole(CDB). 3. Cyclohexyl polysulfides(CPS) and cyclohexylthioamine are believed to be also involved in the cure retardation. 4. The new retarder can stop crosslinking by intercepting the crosslink precursors. 5. Formation of cyclohexyl polysulfides and their lack of curing property may be responsible for the low state of cure when the new retarde is used. These results are schematically summarized in Figure 7.

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Optical Compensation of IPS-LCD for Symmetric-High-Contrast at Off-Axis Oblique View (측면시야각에서의 대칭적 명암대비비 향상을 위한 IPS-LCD 광학보상)

  • Kim, Tae-Hyeon;Kim, Bong-Sik;Park, Woo-Sang
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.29 no.3
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    • pp.175-180
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    • 2016
  • In this study, we proposed an optical compensation method to improve the symmetricity of contrast ratio for wide viewing angle IPS (in-plane switching) LCD. First, the phase retardation depending on the thickness of compensation film is calculated, and then the phase change is presented at the $Poincar{\acute{e}}$ sphere. The phase retardation and the polarization state of the light passing through the optical elements are caculated by using the EJMM (extended Jones matrix method). In addition, the transmittance and the contrast countour are also calculated by using the Berremann's $4{\times}4$ matrix method. The simulation is carried out for a IPS LC cell with positive A/C/A compensation film. From the standard deviation of the contrast ratio, we confirmed the symmetricity at each viewing angle is inversely proportional to the standard deviation and calculated the optimum design condition of the uniaxial compensation film for the IPS LCD.