• Title/Summary/Keyword: response sueface

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Effects of Lyophilization on Starter Cell of Rifamycin Fermentation (동결건조법이 Rifamycin 발효의 Starter Cell에 미치는 영향)

  • 이동희;조좌형;이노은
    • Microbiology and Biotechnology Letters
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    • v.20 no.4
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    • pp.470-476
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    • 1992
  • Upon lyophilization of Nocardia mediterranei, the effects of cryoprotectants, cell concentration and drying time on viability were examined, The data were treated by computer according to response surface analysis. As a result, the maximum value of presumed viability was 39.3% under the optimal conditions of 1l.6%(v/v) sucrose, $1.16{\times}10^{11}$(CFU/ml) cell concentration, and drying time for 6.18 hrs. We also used the starter cell of rehydrated solution after lyophilization in industrial production, obtained the fermentation pattern and the purity of rifamycin B which were the same with control (FVM) and it is possible for us to use N mediterranei as a starter cell after the storage of lyophilization for 18 months.

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A Study on the Characteristics of IT Innovations (정보기술 혁신 특성에 관한 연구)

  • 백상용;박경수
    • Journal of Information Technology Application
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    • v.3 no.3
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    • pp.71-90
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    • 2001
  • Research on innovation has a long tradition from various disciplines. MIS research has also been interested in the innovation adoption because IS development and implementation can be regarded as an innovation process. To deal with IT innovations, MIS research adopted existing innovation(diffusion) theories which have been developed on general innovation phenomena. However, the MIS innovation research revealed that there exist some limitations in applying the innovation theories to IT innovations and proposed that research on IT innovations should reflect the unique characteristics of IT. The purpose of this study is twofold; first, to synthesize the past research and propose the uniqueness of IT innovations and second, to survey the Perceptions of managers on If innovations. Three unique characteristics of IT innovations are derived from the past research which are (1) knowledge barriers, (2) increasing returns, (3) organizational decision. Data collected from 68 Korean managers showed that the perceptions of managers support the uniqueness of IT innovations. Some recommendations to facilitate IT innovations are discussed and further research directions are suggested.

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