• Journal of Korean Traditional Oncology
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• v.17 no.1
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• pp.1-7
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• 2012

Objective : The association of cancer survival and components of the systemic inflammatory response, combined to form inflammation-based prognostic scores (modified Glasgow Prognostic Score (GPS), Neutrophil Lymphocyte Ratio, Platelet Lymphocyte Ratio) is reviewed in this article. Methods and Results : With extensive research of papers in the PubMed, there is good evidence that preoperative measures of the systemic inflammatory response predict cancer survival, independent of tumor stage, in primary operable cancer. GPS also shows its prognostic value as a predictor of survival, independent of tumor stage, performance status and treatment in a variety of advanced cancer. GPS is associated with chemotherapy related toxicities as well as response to treatment and C-reactive protein shows its clinical value as a monitor of chemotherapy response. The systemic inflammatory response is closely related to cachexia and may be suitable measure for the clinical definition of cancer cachexia. Conclusion : Anticipated survival using the inflammation-based prognostic score is a major factor to be taken into consideration when deciding whether active intervention including surgery and chemotherapy or palliation therapy including acupuncture and herb medication is appropriate.

• Journal of Korean Association for Spatial Structures
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• v.18 no.1
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• pp.55-65
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• 2018

In order to reduce the seismic response of the spatial structure, a seismic isolation system with sufficient flexibility is used. The natural period of structure with seismic isolation system got be long to avoid prominent period. In this study, The seismic response of the truss-arch structure, which is modeled in three types according to the rise-span ratio is analyzed on El-centro, Northridge and Artificial Earthquake and compared with the seismic response of the truss-arch structure with lead rubber bearing(LRB). When seismic load is applied to the truss arch with isolation system, the horizontal acceleration response of the truss arch is reduced and vertical seismic response is also reduced. The application of the seismic isolation system is effective in controlling the seismic response.

• Structural Engineering and Mechanics
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• v.23 no.5
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• pp.505-523
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• 2006

An unrestrained plane rigid body resting on a horizontal surface which shakes horizontally and vertically may assume one of the five modes of response: rest, slide, slide-rock, rock, and free flight. The first four are nontrivial modes of motion. It is important to study which one of these responses is started from rest as in most studies it is often assumed that the initial mode is the particular mode of response. Criteria governing the initiation of modes are first briefly discussed. It is shown that the commencement of response modes depends on the aspect ratio of the body, coefficients of static and kinetic friction at the body-base interface, and the magnitude of maximum base accelerations. Considering the last two factors as random variables, the initiation of response modes is next studied from a probabilistic point of view. Type 1 extreme value and lognormal distributions are employed for maximum base excitations and coefficient of friction respectively. Analytical expressions for computing the probability values of each mode of response are derived. The effects of slenderness ratio, vertical acceleration, and statistical distributions of maximum acceleration and coefficient of friction are shown through numerical results and plots.

• Journal of the Earthquake Engineering Society of Korea
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• v.23 no.4
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• pp.201-209
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• 2019

Response modification factors of school facilities for non-seismic RC moment frames with partial masonry infills in 'Manual for Seismic Performance Evaluation and Retrofit of School Facilities' published in 2018 were investigated in the preceding study. However, since previous studies are based on 2D frame analysis and limited analysis conditions, additional verification needs to be performed to further apply various conditions including orthogonal effect of seismic load. Therefore, this study is to select appropriate response modification factors of school facilities for non-seismic RC moment frames with partial masonry infills by 3D frame analysis. The results are as follows. An appropriate response modification factor for non-seismic RC moment frames with partial masonry infills is proposed as 2.5 for all cases if the period is longer than 0.6 seconds. Also if the period is less than 0.4 seconds and the ratio of shear-controlled columns is less than 30%, 2.5 is chosen too. However, if the period is less than 0.4 seconds and the ratio of shear-controlled columns is higher than 30%, the response modification factor shall be reduced to 2.0. If the period is between 0.4 and 0.6 seconds, then linearly interpolates the response correction factor.

• Journal of Korea Society of Digital Industry and Information Management
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• v.10 no.4
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• pp.97-107
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• 2014

The development of ICT has led positive aspects such as popularization of Internet. It, on the other hand, is causing a negative aspect, Cyber Terror. Although the causes for recent and continuous increase of cyber security incidents are various such as lack of technical and institutional security measure, the main cause which threatens the cyber security is the users' lack of awareness and attitude. The purpose of this study is the positive analysis of how the personal and job characteristics influence the cyber security training participation rate and the response ability to cyber terror response training with a sample case of K-corporation employees. In this paper, the relationship among career, gender, department, whether he/she is a cyber security specialist, whether he/she is a regular employee), "ratio of cyber security training courses during recent three years", "ratio that he/she has opened the malicious email in cyber terror response training during recent three years", "response index of virus active-x installation (higher index means poorer response)" is closely examined. Moreover, based on the examination result, the practical and political implications regarding K-corporation's cyber security courses and cyber terror response training are studied.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.5
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• pp.2753-2758
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• 2013

Various studies examining the relationship between Ezrin overexpression and response to chemotherapy and clinical outcome in patients with osteosarcoma have yielded inconclusive results. We accordingly conducted a meta-analysis of 7 studies (n = 318 patients) that evaluated the correlation between Ezrin and histologic response to chemotherapy and clinical prognosis (death). Data were synthesized in receiver operating characteristic curves and with fixed-effects and random-effects likelihood ratios and risk ratios. Quantitative synthesis showed that Ezrin is not a prognostic factor for the response to chemotherapy. The positive likelihood ratio was 0.538 (95% confidence interval [95% CI], 0.296- 0.979; random-effects calculation), and the negative likelihood ratio was 2.151 (95% CI, 0.905- 5.114; random-effects calculations). There was some between-study heterogeneity, but no study showed strong discriminating ability. Conversely, Ezrin positive status tended to be associated with a lower 2-year survival (risk ratio, 2.45; 95% CI, 1.26-4.76; random-effects calculation) with some between-study heterogeneity that disappeared when only studies that employed immunohistochemistry were considered (risk ratio, 2.97; 95% CI, 2.01- 4.40; fixed-effects calculation). To conclude, Ezrin is not associated with the histologic response to chemotherapy in patients with osteosarcoma, whereas Ezrin positivity was associated with a lower 2-year survival rate regarding risk of death at 2 years. Expression change of Ezrin is an independent prognostic factor in patients with osteosarcoma.

• The Journal of Internal Korean Medicine
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• v.31 no.2
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• pp.264-272
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• 2010

Objectives : This study was carried out to measure perceptions about Traditional Korean Medicine hospitals and provide data for improvement of TKM hospital management. Methods : We surveyed the general population from 1st to 17th December, 2008, and patients visiting a TKM hospital from 1st June to 9th December, 2008. Results : Result as follows. 1. The response ratio for the generally preferred medical institution was in the order of western medical clinic, pharmacy, general hospital, TKM clinic, TKM hospital. 2. The response ratio for the preferred medical institution for herbal medicine treatment was in the order of TKM clinic, herbal medicine store, TKM hospital, pharmacy. The preferred medical institution for acupuncture treatment was in the order of TKM clinic, TKM hospital, acupuncture clinic, public health center. 3. The most common response to reason for receiving traditional Korean medical care was "traditional Korean medical care is more effective than western medical care." 4. The proportion of first treatment and second treatment of patients visiting at TKM hospital was about 1:1. 5. 72.3% of patients had been to another medical institution. 6. The response ratio for the first visited medical institution for the same disease was in the order of general hospital, western medical hospital, western medical clinic, TKM clinic. 7. The response ratio for the concern about TKM treatment was in the order of expensive charge for TKM treatment, uncertainty of TKM treatment effect. Conclusions : Through this research, we can understand the perception about TKM hospital treatment of the general population and patients visiting TKM hospitals.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2009.05a
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• pp.49-52
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• 2009

The response times of monopropellant thrusters at a pulse mode were investigated experimentally as design parameters and feed pressure conditions. Five different model thrusters as injection direction/uniformity, aspect ratio of reactor, volumes of manifold and chamber were designed. As a results, two parameters, aspect ratio and manifold volume, were directly related to response characteristics. Additionally, chugging instability at reaction chamber was observed when pressure drop across the catalyst bed was increased due to high aspect ratio or when low pressure was built at reaction chamber.

• Journal of Korean Association for Spatial Structures
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• v.18 no.2
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• pp.43-50
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• 2018

In this study, TMD(Tuned Mass Damper) is installed in a retractable-roof spatial structure in order to investigate dynamic response characteristics according to mass ratio and installed position of TMD on large spatial structures. The example analytical model is generated based on the Singapore sports hub stadium. Twenty eight analytical models are used to investigate optimal installation position of TMD for the example retractable-roof spatial structure using 4 to 16 TMDs. The mass of one TMD is set up 1% of total mass at the example analytical model. Displacement response ratio of model with TMD is compared with that of base model without TMD. It has been found from numerical simulation that it is more effective to install TMD at the edge of the spatial structure rather than to concentrate the TMD at the center of the spatial structure.

• Journal of the Earthquake Engineering Society of Korea
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• v.7 no.2
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• pp.39-48
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• 2003

This paper present a summary of the results of statistical study of the ductility factor which is key component of response modification factor(R). To compute the ductility factor, a group of 1,860 ground motions recorded from various earthquake was considered. Based on the local site conditions at the recording station, ground motions were classified into four groups according to average shear wave velocity. Inleastic spectrum were computed for elastic perfectly plastic SDOF systems undergoing different level of inelastic deformation and period. Ductility factors were calculated by deviding elastic response spectrum by inelastic response spectrum. The influence f displacement ductility ratio, site condition, magnitude and epicentral distance on ductility factors were studied. The coefficient of variation was computed to evaluated the dispersion of ductility factors as the defined ratio of the standard deviation to the mean.