• 한국지진공학회논문집
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• 제25권2호
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• pp.53-58
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• 2021

Nuclear power plant's safety against seismic events is evaluated as risk values by probabilistic seismic safety assessment. The risk values vary by the seismic failure correlation between the structures, systems, and components (SSCs). However, most probabilistic seismic safety assessments idealized the seismic failure correlation between the SSCs as entirely dependent or independent. Such a consideration results in an inaccurate assessment result not reflecting real physical phenomenon. A nuclear power plant's seismic risk should be calculated with the appropriate seismic failure correlation coefficient between the SSCs for a reasonable outcome. An accident scenario that has an enormous impact on a nuclear power plant's seismic risk was selected. Moreover, the probabilistic seismic response analyses of a nuclear power plant were performed to derive appropriate seismic failure correlations between SSCs. Based on the analysis results, the seismic failure correlation coefficient between SSCs was derived, and the seismic fragility curve and core damage frequency of the loss of essential power event were calculated. Results were compared with the seismic fragility and core damage frequency of assuming the seismic failure correlations between SSCs were independent and entirely dependent.

• Earthquakes and Structures
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• 제22권2호
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• pp.169-184
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• 2022

The importance of seismicity in developing countries and the strengthening of buildings is a topic of major importance. Therefore, the study of several solutions with the development of new technologies is of great importance to investigate the damage on retrofitted structures by using probabilistic methods. The Federal Emergency Management Agency considers three types of performance levels by considering different scenarios, intensity and duration. The selection and scaling of ground motions mainly depends on the aim of the study. Intensity-based assessments are the most common and compute the response of buildings for a specified seismic intensity. Assessments based on scenarios estimate the response of buildings to different earthquake scenarios. A risk-based assessment is considered as one of the most effective. This research represents a practical method for developing countries where exists many active faults, tall buildings and lack of good implementable approaches. Therefore, to achieve the main goal, two high-rise steel buildings have been modeled and assessed. The contribution of buckling-restrained braces in the elastic design of both buildings is firstly verified. In the nonlinear static range, both buildings presented repairable damage at the central top part and some life safety hinges at the bottom. The nonlinear incremental dynamic analysis was applied by 15 representative/scaled accelerograms to obtain levels of performance and fragility curves. The results shown that by using probabilistic methods, it is possible to estimate the probability of collapse of retrofitted buildings by buckling-restrained braces and tuned mass dampers, which are practical retrofitting options to protect existing structures against earthquakes.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2006년도 춘계학술대회논문집
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• pp.1280-1284
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• 2006

This paper describes the methodology for environmental assessments of traffic noise sources. An attempt is made to establish evaluation scale relationships between noise quality Parameters and subjective degrees annoyance. Subjective experimental was conducted to determine the subjective degrees annoyance that scaling score compare with reference and varieties noise source about modified traffic noises with $40{\sim}85dB$. Also a correlation analysis between noise rating index and satisfactory percentage of the noise dose response curves varied with response was conducted. As a result of study, subjective annoyance degree has not correlation of proportional linearity to the A weight noise level, but has correlation of proportional linearity to the index composed to loudness and tonality. It is suggested to be resonable level 4.9 (equivalence about 53dB) index on the out door noise limits for traffic noise and to be 6 step scale base on the linearity for evaluation traffic noise.

• The Korean Journal of Pain
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• 제8권1호
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• pp.25-30
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• 1995

Anlgesic agents against visceral pain typically rely on a noxious chemical irritation of the peritoneum, e. g., acetic acid and phenylquinone writhing test. While useful, this type of assay depends upon an acute inflammation and the release of local alogens. Further, ethical and scientific constraints prevent repeated assessments in a single animal, thereby compounding the difficulty of assessing tolerance development to analgesic agents. To overcome these constraints, Colburn et al. developed a model for mechanical visceral pain model (VPM) based on a repeatable and reversible duodenal distention in the rat. A chronic indwelling intraduodenal balloon catheter is well tolerated and upon inflation produces a writhing response graded in proportion to distention. This response is inhibited by morphine in a dose dependent manner. We found that a model for visceral pain was thought to be a great value.

• Structural Engineering and Mechanics
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• 제17권1호
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• pp.29-50
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• 2004

A total life model was developed to assess the service life of aging aircraft. The primary focus of this paper is the development of crack growth life projection using the response surface method. Crack growth life projection is a necessary component of the total life model. The study showed that the number of load cycles N needed for a crack to propagate to a specified size can be linearly related to the geometric parameter, material, and stress level of the component considered when all the variables are transformed to logarithmic values. By the Central Limit theorem, the ln N was approximated by Gaussian distribution. This Gaussian model compared well with the histograms of the number of load cycles generated from simulated crack growth curves. The outcome of this study will aid engineers in designing their crack growth experiments to develop the stochastic crack growth models for service life assessments.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2004년도 추계 학술발표회 제16권2호
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• pp.341-344
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• 2004

In the present research, slump, modulus of rupture (MOR) and flexural toughness $(I_{30})$ of high performance hybrid fiber reinforced concrete (HPHFRC) mixed with micro-fiber (carbon fiber) and macro-fiber (steel fiber) and replaced with silica fume were assessed with the analysis of variance (ANOVA). Steel fiber was a considerable significant factor in aspect of the response values of MOR and boo Based on the significance of factors related to response values from ANOVA, following assessments were available; Slump decrease: carbon fiber >> steel fiber > silica fume; MOR: steel fiber > silica fume > carbon fiber; $I_{30}$: steel fiber > carbon fiber > silica fume. Steel fiber $1.0\%$, carbon fiber $0.25\%$ and silica fume $5.0\%$, and Steel fiber $1.0\%$, carbon fiber $0.25\%$ and silica fume $2.5\%$ were obtained as the most optimum mixture.

• 대한예방의학회:학술대회논문집
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• 대한예방의학회 1994년도 교수 연수회(환경)
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• pp.426-430
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• 1994

The assessment of exposure is an important component of the risk assessment process. Exposure information is used in risk assessment in at least two ways: 1) in the identification of hazards and the epidemiologic research investigating exposure-response relationships and 2) in the development of population exposure estimates. In both of these cases, the value of a chemical risk assessment is enhanced by improvements in the quality of exposure assessments. The optimum exposure assessment is the direct measurement of population exposure; however, such measurements are rarely available. Recent developments in methods for exposure assessment allow estimates to be made that are valid representations of actual exposure. The use of these exposure estimates to classify exposures correctly enhances the likelihood that causal associations between exposure and response will be correctly identified and that population risks will be accurately assessed.

• Steel and Composite Structures
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• 제15권1호
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• pp.15-39
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• 2013

The sensitivities of a structural response due to variation of its design parameters are prerequisite in the majority of the algorithms used for fundamental problems in engineering as system uncertainties, identification and probabilistic assessments etc. The paper presents the concept of probabilistic sensitivity of suspension bridges with respect to near-fault ground motion. In near field earthquake ground motions, large amplitude spectral accelerations can occur at long periods where many suspension bridges have significant structural response modes. Two different types of suspension bridges, which are Bosporus and Humber bridges, are selected to investigate the near-fault ground motion effects on suspension bridges random response sensitivity analysis. The modulus of elasticity is selected as random design variable. Strong ground motion records of Kocaeli, Northridge and Erzincan earthquakes are selected for the analyses. The stochastic sensitivity displacements and internal forces are determined by using the stochastic sensitivity finite element method and Monte Carlo simulation method. The stochastic sensitivity displacements and responses obtained from the two different suspension bridges subjected to these near-fault strong-ground motions are compared with each other. It is seen from the results that near-fault ground motions have different impacts stochastic sensitivity responses of suspension bridges. The stochastic sensitivity information provides a deeper insight into the structural design and it can be used as a basis for decision-making.

• Smart Structures and Systems
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• 제24권4호
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• pp.507-524
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• 2019

A Bayesian dynamic linear model (BDLM) is presented for a data-driven analysis for response prediction and load effect separation of a revolving auditorium structure, where the main loads are self-weight and dead loads, temperature load, and audience load. Analyses are carried out based on the long-term monitoring data for static strains on several key members of the structure. Three improvements are introduced to the ordinary regression BDLM, which are a classificatory regression term to address the temporary audience load effect, improved inference for the variance of observation noise to be updated continuously, and component discount factors for effective load effect separation. The effects of those improvements are evaluated regarding the root mean square errors, standard deviations, and 95% confidence intervals of the predictions. Bayes factors are used for evaluating the probability distributions of the predictions, which are essential to structural condition assessments, such as outlier identification and reliability analysis. The performance of the present BDLM has been successfully verified based on the simulated data and the real data obtained from the structural health monitoring system installed on the revolving structure.

• Asian Pacific Journal of Cancer Prevention
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• 제14권4호
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• pp.2401-2406
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• 2013

From January 1, 2008 to March 31, 2010, 101 patients with stage II-III breast cancer were enrolled in this study and subjected to an anthracycline-based neoadjuvant chemotherapy regimen with or without docetaxel. Surgery was performed after 2-6 cycles of chemotherapy, and the clinical response was determined by pathological and histochemical assessments. The clinical response rate, as indicated by complete response (CR), partial response (PR), stable disease (SD), and progressive disease (PD), were 6.9, 52.5, 36.6, and 4.0%, respectively. A multivariable correlation analysis indicated that the overall clinical response rate correlated with the number of metastatic lymph nodes, number of chemotherapy cycles, and vessel invasion status. Importantly, the CR rate was only associated with the number of chemotherapy cycles. Nonparametric tests failed to detect a correlation between HER2 or Topo $II{\alpha}$ status and clinical response to neoadjuvant chemotherapy in these patients. When they were stratified by HER2 or HR status, for HER2-positive patients the CR rate was associated with vessel invasion and Topo $II{\alpha}$ status. Based on our findings, we propose that HR, HER-2 and Topo $II{\alpha}$ are not putative predictive biomarkers of chemotherapy outcome for breast cancer patients. Topo $II{\alpha}$ expression level was only inversely correlated with CR rate among HR-positive patients. Importantly, the achievement of CR was largely related to the number of chemotherapy cycles.