• Journal of the Korean Society of Radiology
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• v.15 no.6
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• pp.861-867
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• 2021

Since SBRT takes up to 1 hour from 30 minutes to treatment fraction once or three to five times, there is a possibility of setup error during treatment. To reduce these set-up errors and give accurate doses, we intend to evaluate the usefulness of pre-treatment and post-treatment error values by imaging CBCT again to determine postural movement due to pre-treatment coordinate values using pre-treatment CBCT. On average, the range of systematic errors was 0.032 to 0.17 on the X and Y,Z axes, confirming that there was very little change in movement even after treatment. Tumor centripetal changes (±SD) due to respiratory tuning were 0.11 (±0.12) cm, 0.27 (±0.15) cm, and 0.21 cm (±0.31 cm) in the X, Y and Z directions. The tumor edges ±SD were 0.21 (±0.18) cm, 0.30 (±0.23) cm, and 0.19 cm (±0.26) cm in the X, Y and Z directions. The (±SD) of tumor-corrected displacements were 0.03 (±0.16) cm, 0.05 (±0.26) cm, and 0.02 (±0.23) cm in RL, AP, and SI directions, respectively. The range of the 3D vector value was 0.11 to 0-.18 cm on average when comparing pre-treatment and CBCT, and it was confirmed that the corrected set-up error was within 0.3 cm. Therefore, it was confirmed that there were some changes in values depending on some older patients, condition on the day of treatment, and body type, but they were within the significance range.

• Journal of The Korean Society of Integrative Medicine
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• v.7 no.2
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• pp.1-10
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• 2019

Purpose : To investigate the relationship between breathing pattern disorder and joint position error (JPE) in patients with chronic low back pain (CLBP). Methods : Thirty nine patients with CLBP participated. End-tidal $CO_2$ and respiration rate (RR) were measured using a capnography. Breathing-hold time (BHT) and Nijmegen Questionnaire (NQ) were investigated. Thoracic excursion was measured with a cloth tape measurement technique. Joint position error were measured using a small laser point mounted on a lightweight headband. they were asked to relocate the head, after the neck movement on the horizontal plane. Pearson 's test was used for correlation analysis between respiratory variables and JPE in patients with CLBP. Independent t-test was used to verify the difference between thoracic and diaphragm breathing pattern in patients with CLBP. The significance level was set at 0.05. Results : There was a significant correlation between JPE (LR) and JPE (RR, EX) (r=.639, r=.813) (p<.001) and a low negative correlation with end-tidal $CO_2$ (r=-.357) (p<.05). There was a significant correlation between RR and JPE (EX) (r=.750) (p<.001). There was a low correlation between JPE (EX) and NQ (r=.333) (p<.05). There was a somewhat high negative correlation between NQ and thoracic excursion (r=-.528) (p<.001). There was a somewhat high negative correlation between thoracic excursion and JPE (LR, RR, EX) (r=-.470, r=-.484, r=-.602) (p<.001). There were no significant differences in the RR, BHT, NQ, and thoracic excursion between the thoracic and diaphragmatic breathing (p>.05). There was a significant difference in the JPE (EX), end - tidal $CO_2$, and VAS values between the thoracic and diaphragm breathing (p<.05). Conclusion : There was a correlation between JPE (EX) and NQ in patients with CLBP, and correlation between thoracic excursion and JPE (LR, RR, EX) and NQ. There was a significant difference in the JPE (EX), end-tidal $CO_2$ level, and VAS value in the comparison of thoracic breathing and diaphragm breathing. The results showed that breathing patterns and JPE were related to each other.

• Journal of The Korean Dental Society of Anesthesiology
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• v.14 no.1
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• pp.63-71
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• 2014

Extension of advanced odontogenic infection from deep neck fascial spaces into the mediastinum is heralded by chest pain, dyspnea, fever, and radiographic demonstration of mediastinal widening. The critical care should be done in a team approach by multiple medical and dental departments, such as, oral & maxillofacial surgery, otolaryngology, anesthesiology, chest surgery, and infection medicine. Especially, fluid & drug therapy, adequate incision & drainage and systemic supportive psychosedation care are important. But, acute hyperventilation can be produced by several distinct causes: severe anxiety, respiratory alkalosis, increased blood catecholamine levels, and a decrease in the level of the ionized calcium in the blood. The orofacial fears about acute pain, trismus, dysphagia, swelling and oral surgical treatment lead to the severe anxiety and increased blood catecholamine level by stress. Therefore, the most dental patient should be cared gently as the stress reduction protocol. In spite of the care, hyperventilation was occurred during psychosedation and local anesthesia for incision and drainage of the masticatory fascial space abscess with deep neck infection & mediastinitis. We suggest that the dental patient with advanced odontogenic infection must be attention for the manifestation of hyperventilation, especially in the medically compromised conditions.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.9
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• pp.4413-4416
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• 2012

Aim: Individual differences in chemosensitivity and clinical outcome in non-small cell lung cancer (NSCLC) patients treatment with platinum-based chemotherapy may be due to genetic factors. Our study aimed to investigate the prognostic role of GSTP1, XRCC1 and XRCC3 in NSCLC patients treated with chemotherapy. Methods: A total of 460 cases were consecutively selected from The Affiliated Hospital of Nantong University between Jan. 2003 to Nov. 2006, and all were followed-up until Nov. 2011. Genotyping of GSTP1 Ile105Val, XRCC1 Arg194Trp, XRCC1 Arg399Gln and XRCC3 Thr241Met was conducted by duplex polymerase-chain-reaction with confronting-two-pair primer methods. Results: Patients with GSTP Val/Val exhibited a shorter survival time, and had a 1.89 fold greater risk of death than did those with the IIe/IIe genotype. For XRCC1 Arg194Trp, the variant genotype Trp/Trp was significantly associated with a decreased risk of death from NSCLC when compared with the Arg/Arg. Individuals carrying XRCC1 399Gln/Gln genotype had a longer survival time, with a lowered risk of death from NSCLC. Conclusion: This study indicated that GSTP1 Ile105Val, XRCC1 Arg194Trp and XRCC1Arg399Gln genes have a role in modifying the effect of platinum-based chemotherapy for NSCLC patients in a Chinese population. Our findings provide information for therapeutic decisions for individualized therapy in NSCLC cases.

• Journal of the Korean Society of Physical Medicine
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• v.9 no.1
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• pp.107-113
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• 2014

PURPOSE: The purpose of this study was to investigate the correlation between craniovertebral angle (CVA) and cardiorespiratory function ($VO_2max$ and $VCO_2max$) in young adults. METHODS: For this study, the students of D college were questioned and 50 members of D college were participated in our research.. Side-view pictures of each subject were taken in standing positions, in order to assess forward head posture (FHP) by measuring the craniovertebral angle. The craniovertebral angle was measured as the angle between a horizontal line at C7 and a line from the tragus of the ear to the spinous process of C7. And $VO_2max$ and $VCO_2max$ were measured by Quark CPET (cosmed co, USA) while the subjects were performed the treadmill running task of a intensity to set with respiratory mask. Subjucts were Then Pearson's correlation coefficient was calculated to estimate the relationship between craniovertebral and cardiorespiratory function ($VO_2max$ and $VCO_2max$) using SPSS for window. RESULTS: There was a significant positive correlation between craniovertebral angle and $VO_2max$ during treadmill running task (r=0.528, p<0.05). And there was a significant positive correlation between craniovertebral angle and $VO_2max$ during treadmill running task (r=0.566, p<0.05). CONCLUSION: Foreward head posture is related to cardiorespiratory function, and it has a negative correlation with cardiorespiratory function.

• Pediatric Infection and Vaccine
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• v.19 no.3
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• pp.157-161
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• 2012

Streptococcus anginosus is a member of Streptococcus milleri group, and is found in the oral mucosa, respiratory tract, and gastrointestinal tract as normal flora. It can develop into a disease in patients with deteriorating clinical condition or with clinical risk factors. A previously healthy 15-year-old boy was admitted due to fever, abdominal discomfort and vomiting which lasted for 7 days. He had a history of dental procedure 1 day before the development of fever. He was diagnosed with acute acalculous cholecystitis based on the clinical, laboratory, and imaging finding, and S. anginosus was isolated from the blood culture. The patient was successfully treated with antibiotic therapy.

• Journal of Chest Surgery
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• v.35 no.8
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• pp.594-598
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• 2002

Amiodarone is an iodinated benzofuran derivative that has been proved effective in the control of supraventricular and ventricular arrhythmias refractory to other antiarrhythmic drugs. In patients treated with amiodarone, subsequent surgical intervention is a common clinical scenario, but unfortunately we do not have definite data about complications due to amiodarone after cardiac surgery. Some reports have shown that amiodarone treatment can be associated with a state of $\alpha$-adrenergic and $\beta$-adrenergic receptor blockade, which requires more pacing and epinephrine infusion for perioperative hemodynamic support. And some reports have also identified a severe form of ARDS in patients on amiodarone therapy which was associated with siginificant morbidity and mortality. We exprienced a patient who expired after mitral valve replacement due to amiodarone-induced ARDS; therefore, we report this case with a brief literature.

• The Journal of Internal Korean Medicine
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• v.26 no.3
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• pp.626-633
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• 2005

As age distributions of developed countries grow increasingly top-heavy with elderly, instances of bronchiectasis and pneumonia increase. An elderly patient was diagnosed with pneumonia by radiational examination, which showed pound glass opacity in the right middle lobe. Also, he was diagnosed with bronchiectasis in the honeycomb-like recticular area of the right lower lobe. He said that he was suffering from a cough, phlegm and general weakness. He was treated by oriental medicine treatment exclusively, through herbal medicine and acupuncture therapy. Yukmijihwabg-Tang(六味地黃湯), Gamijinhae-Tang(加味鎭咳湯), and Samchulbobi-Tang(參朮補脾湯) As a result, symptoms of cough phlegm and general weakness improved considerably. These results suggest that oriental medicine treatment is effective in improving quality of life fer chronic respiratory patients.

• Korean Journal of Oriental Medicine
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• v.14 no.1
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• pp.73-83
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• 2008

Background : Kigong(氣功) is to develope a nature-therapy by controling and recovering Jinki(眞氣) and it has common features in Yangsaengbeob(養生法), Doinbeob(導引法) and Jeongkisin(精氣神), but it is rarely researched and applied in clinic examine. Objectives : it is compared and contrasted among Kukseondo(國仙道) Yeonjeongwon(硏精院), Seokmunhoheub(石門呼吸). Result : Kukseondo, Yeonjeongwon, Seokmunhoheub have the same point that beginners breath slowly, deeply and naturally. The breathing in each group becomes deeper gradually by mental and physical relaxation although each group has a different breathing method, and it is similar to Jogigyeol(調氣訣) in Dongeuibogam. Ywasik(臥式) is distinguished by the presence of sensation. The breathing in Kukseondo is Yidanhoheub(二段呼吸), the breathing in Yeonjeongwon is Yugi(留氣) and the breathing in Seokmunhoheub is that the ratio of inhaling and blowing are 6 to 4. The breathing in each group is deep and small, Ki also accumulates in the Below-abdomen between blowing and inhaling. This is confirmed by Sinjunapgi(腎主納氣) theory in Oriental-medicine. There is the breath, which is through skin, in Kigonghoheub(氣孔呼吸) of Samhabdanbeop(三合丹法) and Jolidanbeop(造理丹法) in Kukseondo, it is also in Gwiilbeop(歸一法) of Seokmunhoheub. In Kukseondo's case, the breathing is through skin mainly instead of a respiratory organ. In Seokmunhoheub's case, the circulation of Ki is through skin during breathing. In Oriental-medicine, this is called as Pyejupimo(肺主皮毛) which is connected with lung and skin. The breathing coincide with tension and relaxation of body while the breathing through skin and the absorption of Ki spread sensation over the whole body, but the breathing through skin is just a specific ability from a training.

• Proceedings of the Korean Society of Medical Physics Conference
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• 2004.11a
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• pp.115-118
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• 2004

Respiratory motion in the thorax and abdomen is an important limiting factor in high-precision radiation therapy. The lung tumor and tumor(pancreas, stomach) in abdomen therefore are internal motion due to breathing. We will perform to measurement of dose distributions for these moving tumors. In preliminary study, we investigated displacement of moving tumor such as liver, lung tumor in abdomen with previously reported papers. With reference data, internal movements of tumor are displayed with phantom and moving control device(MCD), which appear three dimension (3-D) motion such as x, y and z axis. These devices are used to access dose delivered in tumor with and without internal motion. The MCD and phantom were used to evaluate a delivered dose under similar condition, although there are not same internal tumor motion. In future, we will obtain the exact evaluation of dose if improved in programed software of moving control device and measure precise internal motion using image modality such as fluoroscopy, simulator in based on this study.