• Journal of the Korea Institute of Information and Communication Engineering
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• v.25 no.11
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• pp.1512-1518
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• 2021

Since single cell RNA sequencing provides the expression profiles of individual cells, it provides higher cellular differential resolution than traditional bulk RNA sequencing. Using these single cell RNA sequencing data, clustering analysis is generally conducted to find cell types and understand high level biological processes. In order to effectively process the high-dimensional single cell RNA sequencing data fir the clustering analysis, this paper uses a variational autoencoder to transform a high dimensional data space into a lower dimensional latent space, expecting to produce a latent space that can give more accurate clustering results. By clustering the features in the transformed latent space, we compare the performance of various classical clustering methods for single cell RNA sequencing data. Experimental results demonstrate that the proposed framework outperforms many state-of-the-art methods under various clustering performance metrics.

• Journal of The Korean Astronomical Society
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• v.38 no.2
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• pp.237-240
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• 2005

We present images of L1551 IRS5 at angular resolutions as high as ${\~}$30 mas, corresponding to a spatial resolution of ${\~}$5 AU, made at 7 mm with the VLA. Previously known to be a binary protostellar system, we show that L1551 IRS5 is likely a triple protostellar system. The primary and secondary components have a projected separation of ${\~}$46 AU, whereas the tertiary component has a projected separation of ${\~}$11 AU from the primary component. The circumstellar dust disks of the primary and secondary components have dimensions of ${\~}$15 AU, whereas that of the tertiary component has a dimension of ${\~}$10 AU. Their major axes are closely, but not perfectly, aligned with each other, as well as the major axis of the surrounding flattened, rotating, and contracting molecular condensation (pseudodisk). Furthermore, the orbital motion of the primary and secondary components is in the same direction as the rotational motion of this pseudodisk. We suggest that all three protostellar components formed as a result of the fragmentation of the central region of the molecular pseudo disk. The primary and secondary components, but apparently not the tertiary component, each exhibits a bipolar ionized jet that is centered on and which emergers perpendicular to its associated dust disk. Neither jets are resolved along their base, implying that they are driven within a radial distance of ${\~}$2.5 AU from their central protostars. Finally, we show evidence for what may be dusty matter streams feeding the two main protostellar components.

• Journal of the Korean Association of Geographic Information Studies
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• v.19 no.3
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• pp.127-143
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• 2016

This study explored the variability in the accuracy of dasymetric population estimation with different grid cell sizes. Dasymetric population maps for Fulton County, Georgia in the US were generated from 30m to 420m at intervals of 30m using an automated intelligent dasymetric mapping technique, population data, and original and simulated land use and cover data. The accuracies of dasymetric population maps were evaluated using RMSE and adjusted RMSE statistics. Lumped fractal dimension values were calculated for the dasymetric population maps generated from resolutions of 30m to 420m using the triangular prism surface area (TPSA) method. The results show that a grid cell size of 210m or smaller is required to estimate population more accurately in terms of thematic accuracy, but a grid cell size of 30m is required to meet an acceptable spatial accuracy of dasymetric population estimation in the study area. The fractal analysis also indicates that a grid cell size of 120m is the optimal resolution for dasymetric population estimation in the study area.

• Korean Journal of Optics and Photonics
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• v.9 no.3
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• pp.146-150
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• 1998

To enhance the resolution and the depth of focus of the patterns whose size reaches the optical resolution limits, the various imaging methods are being tried. Generally in the linear polarization illumination methods, the contrast gap exists between TE mode TM mode according to the pattern direction. However, through the previous research, the elliptical polarization illumination(EPI) method was proposed to overcome this contrast gap. In this research, we investigated the optimal polarization condition to be able to enhance the depth of focus(DOF) for the optional mask which is containing the opposite direction patterns by applying the various polarization conditions including EPI. The DOF according to each polarization condition was obtained by ED-Tree(Exposure-Defocus Tree) for the given exposure dose and CD error boundaries. As the result, we can ascertain th effect of EPI for the enhancement of DOF in some condition of optical system.

• Proceedings of the Korean Society of Medical Physics Conference
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• 2002.09a
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• pp.150-153
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• 2002

High dose rate (HDR) brachytherapy in the treatment of cervix carcinoma has become popular, because it eliminated many of the problems with conventional brachytherapy. In order to improve clinical effectiveness with HDR brachytherapy, dose calculation algorithm, optimization procedures, and image registrations should be verified by comparing the dose distributions from a planning computer and those from a humanoid phantom irradiated. Therefore, the humanoid phantom should be designed such that the dose distributions could be quantitatively evaluated by utilizing the dosimeters with high spatial resolution. Therefore, the small size of thermoluminescent dosimeter (TLD) chips with the dimension of 1/8" and film dosimetry with spatial resolution of <1mm used to measure the radiation dosages in the phantom. The humanoid phantom called a pelvic phantom is made of water and tissue-equivalent acrylic plates. In order to firmly hold the HDR applicators in the water phantom, the applicators are inserted into the grooves of the applicator supporters. The dose distributions around the applicators, such as Point A and B, can be measured by placing a series of TLD chips (TLD-to- TLD distance: 5mm) in three TLD holders, and placing three verification films in orthogonal planes.

• Molecules and Cells
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• v.22 no.1
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• pp.119-125
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• 2006

The rat is an accepted model for studying human psychiatric/neurological disorders. We provide a protocol for total soluble protein extraction using trichloroacetic acid/acetone (TCA/A) from rat (female) whole brain, 10 brain regions and the pituitary gland, and show that two-dimensional gel electrophoresis (2-DGE) using precast immobilized pH (4-7) gradient (IPG) strip gels (13 cm) in the first dimension yields clean silver nitrate stained protein profiles. Though TCA/A precipitation may not be "ideal", the important choice here is the selection of an appropriate lysis buffer (LB) for solubilizing precipitated proteins. Our results reveal enrichment of protein spots by use of individual brain regions rather than whole brain, as well as the presence of differentially expressed spots in their proteomes. Thus individual brain regions provide improved protein coverage and are better suited for differential protein detection. Moreover, using a phosphoprotein-specific dye, ingel detection of phosphoproteins was demonstrated. Representative high-resolution silver nitrate stained proteome profiles of rat whole brain total soluble protein are presented. Shortcomings apart (failure to separate membrane proteins), gel-based proteomics remains a viable option, and 2-DGE is the method of choice for generating high-resolution proteome maps of rat brain and brain regions.

• Journal of Sasang Constitutional Medicine
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• v.18 no.3
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• pp.49-56
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• 2006

1. Objectives We are going to develope 3D Face Recognition Apparatus to analyse the facial characteristics of the Sasangin. In the process, we should identify a Hardware Error Analysis of this Apparatus. 2. Methods We verified The resolution, the repetition ability, the Flatness and the Cylindericity of 3D Face Recognition Apparatus by measuring a triangular pyramid, an exact square pillar and a cylinder. 3. Results and Conclusions In this test, The resolution of 3D-FARA was $0.0368mm{\times}0.0594mm{\times}0.2748mm(X{\times}Y{\times}Z)$, the repetition ability was 0.1187mm, the Flatness was 0.17188mm. the Flatness of triangular pyramid was 1.39034mm and the Cylindericity of cylinder was 3.1306mm. In conclusion, If we use 3D-FARA, It is necessary to complement the site of top of the nose and the outline of face, which is likely to occur hardware error, by using software invention or attaching the Land mark to subject.

• Atmosphere
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• v.22 no.4
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• pp.387-400
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• 2012

This study aims at examining the sensitivity of numerical simulations to the resolution of initial and boundary data, and to an application of WRF (Weather Research and Forecasting) 3DVAR (Three Dimension Variational data Assimilation). To do this, we ran the WRF model by using GDAS (Global Data Assimilation System) FNL (Final analyses) and the KLAPS (Korea Local Analysis and Prediction System) analyses as the WRF's initial and boundary data, and by using an initial field made by assimilating the radar data to the KLAPS analyses. For the sensitivity experiment, we selected a heavy rainfall case of 21 September 2010, where there was localized torrential rain, which was recorded as 259.5 mm precipitation in a day at Seoul. The result of the simulation using the FNL as initial and boundary data (FNL exp) showed that the localized heavy rainfall area was not accurately simulated and that the simulated amount of precipitation was about 4% of the observed accumulated precipitation. That of the simulation using KLAPS analyses as initial and boundary data (KLAPC exp) showed that the localized heavy rainfall area was simulated on the northern area of Seoul-Gyeonggi area, which renders rather difference in location, and that the simulated amount was underestimated as about 6.4% of the precipitation. Finally, that of the simulation using an initial field made by assimilating the radar data to the KLAPS using 3DVAR system (KLAP3D exp) showed that the localized heavy rainfall area was located properly on Seoul-Gyeonggi area, but still the amount itself was underestimated as about 29% of the precipitation. Even though KLAP3D exp still showed an underestimation in the precipitation, it showed the best result among them. Even if it is difficult to generalize the effect of data assimilation by one case, this study showed that the radar data assimilation can somewhat improve the accuracy of the simulated precipitation.

• Korean Journal of Remote Sensing
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• v.24 no.3
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• pp.223-233
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• 2008

In the mid 90's, the U.S. government released images acquired by the first generation of photo reconnaissance satellite missions between 1960 and 1972. The Declassified Intelligent Satellite Photographs (DISP) from the Corona mission are of high quality with an astounding ground resolution of about 2 m. The KH-4A panoramic camera system employed a scan angle of $70^{\circ}$ that produces film strips with a dimension of $55\;mm\;{\times}\;757\;mm$. Since GPS/INS did not exist at the time of data acquisition, the exterior orientation must be established in the traditional way by using control information and the interior orientation of the camera. Detailed information about the camera is not available, however. For reconstructing points in object space from DISP imagery to an accuracy that is comparable to high resolution (a few meters), a precise camera model is essential. This paper is concerned with the derivation of a rigorous mathematical model for the KH-4A/B panoramic camera. The proposed model is compared with generic sensor models, such as affine transformation and rational functions. The paper concludes with experimental results concerning the precision of reconstructed points in object space. The rigorous mathematical panoramic camera model for the KH-4A camera system is based on extended collinearity equations assuming that the satellite trajectory during one scan is smooth and the attitude remains unchanged. As a result, the collinearity equations express the perspective center as a function of the scan time. With the known satellite velocity this will translate into a shift along-track. Therefore, the exterior orientation contains seven parameters to be estimated. The reconstruction of object points can now be performed with the exterior orientation parameters, either by intersecting bundle rays with a known surface or by using the stereoscopic KH-4A arrangement with fore and aft cameras mounted an angle of $30^{\circ}$.

• The Journal of the Acoustical Society of Korea
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• v.42 no.5
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• pp.422-428
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• 2023

Ultrafast ultrasound imaging has been applied to various imaging approaches, including shear wave elastography, ultrafast Doppler, and super-resolution imaging. However, these methods are still challenging in real-time implementation for three Dimension (3D) or portable applications because of their massive data rate required. In this paper, we proposed an adaptive quantization method that effectively reduces the data rate of large Radio Frequency (RF) data. In soft tissue, ultrasound backscatter signals require a high dynamic range, and thus typical quantization used in the current systems uses the quantization level of 10 bits to 14 bits. To alleviate the quantization level to expand the application of ultrafast ultrasound imaging, this study proposed a depth-sectional quantization approach that reduces the quantization errors. For quantitative evaluation, Field II simulations, phantom experiments, and in vivo imaging were conducted and CNR, spatial resolution, and SSIM values were compared with the proposed method and fixed quantization method. We demonstrated that our proposed method is capable of effectively reducing the quantization level down to 3-bit while minimizing the image quality degradation.