• 문화기술의 융합
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• 제9권5호
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• pp.569-582
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• 2023

납축전지는 가장 오래된 충전식 배터리 시스템으로 현재까지 충전식 배터리 분야에서 자리를 지키고 있다. 이 배터리는 다양한 이유로 열폭주 현상이 생기는데 이는 큰 사고로 이어질 가능성이 있다. 그렇기 때문에 열폭주 현상을 예방하는 것은 배터리 관리 시스템의 핵심부분이다. 최근에는 열폭주 위험 배터리 셀을 기계학습으로분류하는 연구가 진행 중이다. 본 논문에서는 비지도학습인 DBSCAN 클러스터링과 통계적 방법을 사용하여 열폭주 위험 셀 탐지 및 검증 알고리즘을 제안하였다. BMS에서 측정한 lead-acid 배터리의 저항 값만을 사용하여 열폭주 위험 셀 분류 실험을 진행하였고 본 논문에서 제안한 알고리즘이 열폭주 위험 셀을 정확히 검출해 냄을 보여주었다. 또한 본 논문에서 제안한 알고리즘을 사용하여 배터리 내 열폭주 위험이 있는 셀과 노이즈가 심한 셀을 분류할 수 있었으며 그리드 서치를 통한 DBSCAN 파라미터 최적화를 통해 열폭주 위험 셀을 초기에 검출해 낼 수 있었다.

• 대한약침학회지
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• 제26권4호
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• pp.319-326
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• 2023

Objectives: The study's goal was to find out whether Chrysanthemum rubellum extract has anti-diabetic properties by concentrating on α-glucosidase and the PTP-1B signaling pathway. C. rubellum flowers were used for extraction using Methanol/water (80/20) as solvent. Methods: LC-MS techniques was used to check the presence of phytoconstituents present in C. rubellum extract. In vitro antidiabetic activity was evaluated using α-glucosidase inhibitory activity and PTP-1B signaling pathway. On Streptozotocin (STZ)-induced rats with diabetes, the in vivo antidiabetic efficacy was assessed using a test for oral glucose tolerance. Results: The phytoconstituents identified in the extract of C. rubellum were apigenin, diosmin, myricetin, luteolin, luteolin-7-glucoside, and Quercitrin as compound 1-6, respectively. Results showed that diosmin exhibited highest α-glucosidase inhibitory activity i.e. 90.39%. The protein level of PTP-1B was lowered and the insulin signalling activity was directly increased by compounds 1-6. The maximum blood glucose levels were seen in all groups' OGTT findings at 30 minutes following glucose delivery, followed by gradual drops. In comparison to the control group, the extract's glucose levels were 141 mg/dL at 30 minutes before falling to 104 mg/dL after 120 minutes. The current study has demonstrated, in summary, that extract with phytoconstituents reduce blood sugar levels in rats. Conclusion: This finding suggests that extract may reduce the chance of insulin resistance and shield against disorders like hyperglycemia.

• Asia pacific journal of information systems
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• 제17권3호
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• pp.105-130
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• 2007

Recently, there is a substantial interest in implementing Business Process Management System(BPMS) among enterprises with the purpose of business process innovation. BPMS redesigns and coordinates business processes in terms of both automated steps and human involvement in order to maximize the value of both involved people and systems. The reason why BPMS is getting attention from top managers is that it has the possibility to optimize the business processes by cycling the process of modeling, execution, monitoring, evaluation, and redesigning work processes. Thus, it has created high expectations about not only productivity improvement but also business process innovation. However. having an innovative nature, which is used for process innovation, BPMS implementation has great potential to stir up employee resistance. The analysis and the discussion about the prevention of the resistance against IS(Information Systems) is important because IS change the way people work and also alter the power structure within the organization, in general. The purpose of this study is to investigate factors that have an impact on the effective adoption of BPMS at the enterprise level. To find out these factors, this study considers two characteristics of BPMS: First. BPMS shares some characteristics with other enterprise-wide IS such as ERP. Second, it has special BPMS-specific characteristics. Due to the lack of previous research on BPMS adoption, interviews were carried out with IT-consultants and CIOs who conducted BPMS projects previously to find out BPMS-specific features that would make BPMS unique when compared to other enterprise-wide IS. As a result, the monitoring function was chosen as the main BPMS-specific factor. Thus, this paper reviewed studies both on enterprise-wide IS adoptions, which applied Technology Acceptance Model (TAM) and secondly on computer based monitoring to find out factors that would influence the employees' perception on the monitoring function of BPMS. Based on the literature review, the study suggested three factors that would have an impact on the employee's perception of the monitoring function: fairness of enterprise evaluation system, fairness of the boss, and self-efficacy of their work. Three factors that would impact the enterprise-wide IS adoption were also set: the shared belief in the benefit of BPMS, training, and communication. Then, these factors were integrated with TAM. Structural equation modeling was used to test hypotheses, out factors that would impact the employees' perception on the monitoring function of BPMS. Based on the literature review the study suggested three factors that would have an impact on the employee's perception of the monitoring function: fairness of enterprise evaluation system, fairness of the boss, and self-efficacy of their work. Three factors that would impact the enterprise-wide IS adoption were also set: the shared belief in the benefit of BPMS, training, and communication. Then, these factors were integrated with TAM. Structural equation modeling was used to test hypotheses. The data analysis results showed that two among three monitoring function related factors - enterprise evaluation system and fairness of the boss - were significant. This implies that employees would worry less about the BPMS implementation as long as they perceive the monitoring results will be used fairly for their performance evaluation. However, employees' high self-efficacy on their job was not a significant factor in their perception of the usefulness of BPMS. This is related to cases that showed employees resisted against the information systems because they automated their works (Markus, 1983). One specific case was an electronic company, where the accounting department workers were requested to redefine their job because their working processes were automated due to BPMS implementation.

• 수산해양기술연구
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• 제42권3호
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• pp.148-157
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• 2006

A model experiment, simulation test using personal computer and real sea trial fishing were carried out to investigate the basic efficiency of bottom trawl net which can be used in the sea mount of North West Pacific, and experimental values were analyzed as the values of full-scale bottom trawl net. Hydrodynamic resistance for the full-scale trawl net according to the Koyama equation was 2.1 times higher than that of simulation and 2.4 times higher than that of model experiment at the average towing velocity. At the 3.5kt's of towing speed, net width of the full-scale trawl net was 2.5% smaller than that of simulation and 8.2% larger than that of model experiment. On the fishing experiment of the full-scale trawl net for the 3.5kt's of average towing speed, average net height of A group(same direction with external force) was 423.5% higher than that of model experiment and 457.1% higher than that of simulation and that of B group(opposite direction with external force) were 283.8% and 306.3% higher than in case of model experiment and Simulation respectively. Net mouth of the full-scale trawl net was 338.1-504.6% higher than those of model experiment and simulation in A group, and 525.2-745.3% higher in B group.

• 시큐리티연구
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• 제26호
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• pp.59-87
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• 2011

경비업법의 주요 내용을 살펴보면, 경비업에 대한 규제적 측면에 치우쳐 있으며, 구체적인 권한 부여에 관한 규정이 명확히 제시되어 있지 않다. 이것은 경비업무을 실질적으로 수행하고 있는 경비원의 권한에 대한 근거 규정의 미비와 그러한 권한의 한계를 명확히 설정하지 못하는 문제를 야기하게 된다. 이에 따라 경비업법상 경비업 주체의 업무 수행의 한계를 부여함과 동시에 경비업무의 원활한 수행을 담보할 수 있는 권한 근거 규정을 도출할 수 있는 해석이 이루어져야 하며, 그러한 단서를 제공하는 것이 경비업법 제7조 제1항의 "관리권"이라 할 수 있다. 경비업법에 규정된 관리권의 범위에는 점유권에 기한 자력구제권을 근거로 하여 자력방위 및 자력탈환권이 포함되며, 사실적 지배행위로서 정지 및 질문권, 출입통제 및 퇴거요구권, 물품 검색 반입 보류 및 금지권 등이 인정된다고 할 것이다. 점유보조자의 지위에서 경비원은 관리권으로부터 도출될 수 있는 사전예방 활동을 할 수 있으며, 이러한 예방활동에도 불구하고 법익 침해가 예상되거나 이루어진 경우 관리권에 근거하여, 소극적 저항행위와 저항수단으로서의 유형력 범위 안에서 실력으로 침해를 저지 할 수 있다. 그리고 그러한 물리적 유형력을 행사하기 위해서는 형법상 위법성조각사유인 정당방위 긴급피난 정당행위의 요건을 구비하여야 한다.

• Nutrition Research and Practice
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• 제10권1호
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• pp.11-18
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• 2016

BACKGROUND/OBJECTIVES: Type 2 diabetes (T2D) is more frequently diagnosed and is characterized by hyperglycemia and insulin resistance. $\small{D}$-xylose, a sucrase inhibitor, may be useful as a functional sugar complement to inhibit increases in blood glucose levels. The objective of this study was to investigate the anti-diabetic effects of $\small{D}$-xylose both in vitro and stretpozotocin (STZ)-nicotinamide (NA)-induced models in vivo. MATERIALS/METHODS: Wistar rats were divided into the following groups: (i) normal control; (ii) diabetic control; (iii) diabetic rats supplemented with a diet where 5% of the total sucrose content in the diet was replaced with $\small{D}$-xylose; and (iv) diabetic rats supplemented with a diet where 10% of the total sucrose content in the diet was replaced with $\small{D}$-xylose. These groups were maintained for two weeks. The effects of $\small{D}$-xylose on blood glucose levels were examined using oral glucose tolerance test, insulin secretion assays, histology of liver and pancreas tissues, and analysis of phosphoenolpyruvate carboxylase (PEPCK) expression in liver tissues of a STZ-NA-induced experimental rat model. Levels of glucose uptake and insulin secretion by differentiated C2C12 muscle cells and INS-1 pancreatic ${\beta}$-cells were analyzed. RESULTS: In vivo, $\small{D}$-xylose supplementation significantly reduced fasting serum glucose levels (P < 0.05), it slightly reduced the area under the glucose curve, and increased insulin levels compared to the diabetic controls. $\small{D}$-xylose supplementation enhanced the regeneration of pancreas tissue and improved the arrangement of hepatocytes compared to the diabetic controls. Lower levels of PEPCK were detected in the liver tissues of $\small{D}$-xylose-supplemented rats (P < 0.05). In vitro, both 2-NBDG uptake by C2C12 cells and insulin secretion by INS-1 cells were increased with $\small{D}$-xylose supplementation in a dose-dependent manner compared to treatment with glucose alone. CONCLUSIONS: In this study, $\small{D}$-xylose exerted anti-diabetic effects in vivo by regulating blood glucose levels via regeneration of damaged pancreas and liver tissues and regulation of PEPCK, a key rate-limiting enzyme in the process of gluconeogenesis. In vitro, $\small{D}$-xylose induced the uptake of glucose by muscle cells and the secretion of insulin cells by ${\beta}$-cells. These mechanistic insights will facilitate the development of highly effective strategy for T2D.

• 한국응용곤충학회지
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• 제61권1호
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• pp.197-210
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• 2022

곤충병원성 진균은 다양한 흡즙형 및 저작형 해충 방제에 적용이 가능하며, 익충과 천적에 낮은 영향을 보여, 화학농약의 대체체로서 관심이 높아지고 있다. 현재까지 전세계적으로 170여개의 제품들이 등록되어 판매되고 있으며, 최근 연구측면에서는 작용기작 및 곤충-진균 상호작용체 구명에 집중하고 있다. 해충 방제를 위한 곤충병원성 진균의 산업화 연구는 초기 살충성이 높은 균주 선발에 집중하였으나, 최근에는 환경 스트레스 인자에 대한 저항성 확보를 포함한 생산성 향상이 해결해야 할 주요 과제이다. 분생포자(conidia)가 주된 처리 형태였지만, 액체배양을 통해 생산되는 아포자(blastospore)의 한계점을 극복하여 대량생산의 경제성을 확보하려는 노력들도 진행되고 있다. 추가로 살충효과를 향상시키기 위해, 형질전환을 비롯한 분자생물학적 연구와 유전자 및 유전체 기능 구명에 집중하고 있다. 해충방제 시장측면에서, 글로벌 작물보호제 기업들은 인수합병 또는 공동 연구개발 형태로 전문 생물농약 기업들과의 협력체계를 구축하고 있으며, 화학농약과 곤충병원성 진균의 tank-mix 전략을 주된 방향성으로 삼고 있다. 현장에서 곤충 생태에 대한 이해를 기반으로 한 생태학적 처리(ecological application)는 곤충병원성 진균의 살충효과를 향상시킬 수 있는 기회가 된다. 앞으로의 디지털팜(digital farming) 기술과 접목된다면, 지상부 해충 방제를 위한 실질적인 적용도 가능하다. 곤충병원성 진균의 산업화를 위해서는 지적재산권 분쟁 해결을 위한 명확한 비교 연구자료 확보도 필요하다. 이와 같은 곤충병원성 진균이 식량생산의 안전성과 경제성을 확보하는 중요한 미생물자원으로 활발히 활용되고 개발되길 기대한다.

• Korean Circulation Journal
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• 제53권7호
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• pp.425-451
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• 2023

Most patients with heart failure (HF) have multiple comorbidities, which impact their quality of life, aggravate HF, and increase mortality. Cardiovascular comorbidities include systemic and pulmonary hypertension, ischemic and valvular heart diseases, and atrial fibrillation. Non-cardiovascular comorbidities include diabetes mellitus (DM), chronic kidney and pulmonary diseases, iron deficiency and anemia, and sleep apnea. In patients with HF with hypertension and left ventricular hypertrophy, renin-angiotensin system inhibitors combined with calcium channel blockers and/or diuretics is an effective treatment regimen. Measurement of pulmonary vascular resistance via right heart catheterization is recommended for patients with HF considered suitable for implantation of mechanical circulatory support devices or as heart transplantation candidates. Coronary angiography remains the gold standard for the diagnosis and reperfusion in patients with HF and angina pectoris refractory to antianginal medications. In patients with HF and atrial fibrillation, longterm anticoagulants are recommended according to the CHA₂DS₂-VASc scores. Valvular heart diseases should be treated medically and/or surgically. In patients with HF and DM, metformin is relatively safer; thiazolidinediones cause fluid retention and should be avoided in patients with HF and dyspnea. In renal insufficiency, both volume status and cardiac performance are important for therapy guidance. In patients with HF and pulmonary disease, beta-blockers are underused, which may be related to increased mortality. In patients with HF and anemia, iron supplementation can help improve symptoms. In obstructive sleep apnea, continuous positive airway pressure therapy helps avoid severe nocturnal hypoxia. Appropriate management of comorbidities is important for improving clinical outcomes in patients with HF.

• 한국정보통신학회논문지
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• 제17권10호
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• pp.2301-2308
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• 2013

재활심리분석시스템으로서 웹이 보편적으로 사용되면서 스팸메시지가 급격히 증가하고 있다. 이의 억제를 위한 메시지통제시스템은 기술적이고 경제적 대안으로 필터시스템과 과금 시스템을 사용하고 있으나 차단오류와 과금저항으로 인한 메시지의 수신과 가용성을 제한한다. 이의 해결을 위해서 불법적인 메시지는 억제하지만 송 수신자에게 유익하고 합법적인 메시지가 폐기되고 상실되는 것을 방지할 수 있는 메시지통제시스템의 우회 모델을 제안하고 이를 사용하여 메시지의 유용성과 가용성을 높여줄 수 있는 웹기반의 메시지통제시스템을 구현하여 모델의 실용성을 검증하였다.

• 기본간호학회지
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• 제19권1호
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• pp.122-133
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• 2012

Purpose: The purpose of this study was to develop a web-based education program on control vancomycin-resistant enterococci (VRE) infections and to identify the effects of the program on knowledge and performance of nursing students. Methods: The web-based VRE infection control education program was developed by using the network-based instructional systems design model. The nursing students in the experimental group could access this web-based education program at any time, and as many times as they wanted, during the clinical training period. Effects were evaluated by assessing knowledge and performance of VRE infection control measures during the clinical training period. Results: The contents of the education program included diagnosis, transmission, and treatment of VRE, contact precautions, hand washing, personal protective equipment, environment management, and quizzes. The lecture portion was filmed in a virtual screen studio using flash animation, video, and sound effects, and it was uploaded on an internet site. The knowledge and performance scores of the experimental group after using the education program were significantly higher than those of the control group. Conclusion: The results suggest that the web-based VRE infection control education program is an effective educational method to enhance knowledge and performance of VRE infection control measures.