• Title/Summary/Keyword: resistance management

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Weeding Effect of Echinochloa oryzoides Resistant to ACCase and ALS Inhibitors by the Leaf Stages (ACCase 및 ALS 저해 제초제 저항성 강피의 엽기별 약제방제효과)

  • Lee, In-Yong;Kwon, Oh-Do;Kim, Chang-Seok;Lee, Jeong-Ran;Shin, Hae-Ryoung;Moon, Byung-Chul;Park, Jae-Eup;Kuk, Yong-In
    • Korean Journal of Weed Science
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    • v.31 no.2
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    • pp.183-191
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    • 2011
  • Weeding effect was investigated based on the leaf stages to several different herbicide treatments for an integrated weed management of herbicide resistant Echinochloa oryzoides to ACCase and ALS inhibitors in a rice field. Efficacy of soil-applied herbicide treatments before resistant E. oryzoides occurred was very effective. Pentaxazon 5% SC showed over 98% of weeding effect although E. oryzoides were emerged 31 days after the treatment. Until the leaf stage of 2.5, five herbicides, azimsulfuron carfenstole 1.05% GR, bensulfuron-methyl benzobicyclone mefenacet 24.52% SC, bensulfuron-methyl fentrazamide 7% SC, bensulfuron-methyl mefenacet oxadiargyl 21.6% SC and mefenacet pyrazosulfuron-ethyl 3.57% GR showed perfect weeding effect. Benzobicyclone mefenacet penoxulam 21.5% SC and mefenacet pyrazosulfuron-ethyl 3.57% GR were effective at the leaf stage of 3.0. It is very important to select the right herbicides for timing and their systematic application for controlling of E. oryzoides resistant to ACCase- and ALS-inhibitors.

Determinants of Erythropoietin Hyporesponsiveness in Management of Anemia in Hemodialysis Patients (혈액투석 환자의 빈혈관리에서 Erythropoietin 반응에 영향을 미치는 인자)

  • Shin, Seung-Hee;Ji, Eun-Hee;Lee, Young-Sook;Oh, Jung-Mi
    • Korean Journal of Clinical Pharmacy
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    • v.21 no.2
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    • pp.122-130
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    • 2011
  • Objective: Although recombinant human erythropoietin (rhEPO) has revolutionized the treatment of anemia in chronic kidney disease (CKD) receiving hemodialysis (HD) with no need of blood transfusion, some patients have a blunted or appear to be resistant to rhEPO. There is a controversy in the causes of rhEPO resistance in maintenance HD patients with anemia. This study is to examine current anemia treatment outcomes and the factors influencing the rhEPO responsiveness in HD patient with CKD. Methods: The clinical parameters or factors relating to erythrompoietin treatment outcomes and erythropoietin responsiveness were collected from the HD patients in two large dialysis centers for three months. The collected paramenters included serum iron, total iron biding capacity (TIBC), transferrin saturation rate, ferritin, albumin, intact PTH, C-reactive protein (CRP), nPCR and medications such as an angiotensin converting enzyme inhbitor, an angiotension II receptor blocker and an HMG-CoA reductase inhibitor (HMG-CoA RI). The data were analyzed to examine the degree of acheiveing the anemia treatment goal and factors relating to ERI. Results: Among total 111 patients, 42 (42.3%) and 47 (37.8%) patients achieved the target Hct and Hb based on the Health Insurance Review and Assessment Services (HIRA) reimbursement criteria. In the higher ERI group (upper quartile), the patients had higher CRP levels (0.5 mg/dl) (p=0.0096), and lower TIBC score (<$240{\mu}g/dl$) (p=0.0027), and less patients were taking HMG-CoA RI (p=0.0019). Male patients (p=0.0204), patients with high TIBC score ($R^2$=0.084, p=0.0021) and patients taking HMG-CoA RI (p=0.0052) required to administer less dose of rhEPO meaning higher erythropoietin responsiveness. Conclusion: Less than 50% of CKD patients were achieving the goals of anemia by erythropoietin administration in large hospitals in Korea even though the goals were lower than those of NKF-K/DOQI practice guideline. The factors influencing ERI were sex, TIBC and HMG-CoA RI administration status, and neither an ACEI nor an ARB did not influence ERI.

An Experimental Study on Properties of Concrete Using Latent Heat Binder (잠열성 결합재를 활용한 콘크리트의 특성에 관한 실험적 연구)

  • Kim, Yong-Ro;Kim, Do-Su;Khil, Bae-Su;Kim, Ook-Jong;Lee, Do-Bum
    • Journal of the Korea Concrete Institute
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    • v.20 no.5
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    • pp.661-668
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    • 2008
  • It is necessary to develop a new technology for effectively reducing hydration heat and controlling thermal cracking caused increasing construction of large size massive concrete structures such as mat foundation of high-rise building, grandiose bridge, and LNG tank. Therefor, to develop a new technology for reducing hydration heat of large size massive concrete in this study, after developing the latent heat binder for controling hydration heat of concrete by application of latent heat material, it was investigated basic properties and durability such as slump, air content and compressive strength, shrinkage properties, permeability, freezing and thawing resistance, corrosion, and hydration heat generation properties of concrete using latent heat binder. As a test result, it was confirmed that latent heat binder was not affected adversely the basic property and durability of concrete, and was advanced on the reduction of hydration heat and control of thermal crack. It is expected to be applied as the excellent technology on the management of hydration heat and thermal crack in large size mass concrete structures.

Study on the Damage Pattern Analysis of a 3 Phase 22.9/3.3kV Oil Immersed Transformer and Judgment of the Cause of Its Ignition (3상 22.9/3.3kV 유입변압기의 소손패턴 해석 및 발화원인 판정에 관한 연구)

  • Choi, Chung-Seog
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.60 no.6
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    • pp.1274-1279
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    • 2011
  • The purpose of this paper is to present the manufacturing defect and damage pattern of a 3 phase 22.9/3.3kV oil immersed transformer, as well as to present an objective basis for the prevention of a similar accident and to secure data for the settlement of PL related disputes. It was found that in order to prevent the occurrence of accidents to transformers, insulating oil analysis, thermal image measurement, and corona discharge diagnosis, etc., were performed by establishing relevant regulation. The result of analysis performed on the external appearance of a transformer to which an accident occurred, the internal insulation resistance and protection system, etc., showed that most of the analysis items were judged to be acceptable. However, it was found that the insulation characteristics between the primary winding and the enclosure, those between the ground and the secondary winding, and those between the primary and secondary windings were inappropriate due to an insulating oil leak caused by damage to the pressure relief valve. From the analysis of the acidity values measured over the past 5 years, it is thought that an increase in carbon dioxide (CO2) caused an increase in the temperature inside the transformer and the increase in the ethylene gas increased the possibility of ignition. Even though 17 years have passed since the transformer was installed, it was found that the system's design, manufacture, maintenance and management have been performed well and the insulating paper was in good condition, and that there was no trace of public access or vandalism. However, in the case of transformers to which accidents have occurred, a melted area between the upper and the intermediate bobbins of the W-phase secondary winding as well as between its intermediate and lower bobbins. It can be seen that a V-pattern was formed at the carbonized area of the transformer and that the depth of the carbonization is deeper at the upper side than the lower side. In addition, it was found that physical bending and deformation occurred inside the secondary winding due to non-uniform pressure while performing transformer winding work. Therefore, since it is obvious that the accident occurred due to a manufacturing defect (winding work defect), it is thought that the manufacturer of the transformer is responsible for the accident and that it is lawful for the manufacture to investigate and prove the concrete cause of the accident according to the Product Liability Law (PLL).

A study on a way to use fluorine and the recognition level by the education career periods of elementary school teachers in Jinhae region (진해지역 초등학교 교사의 교육경력에 따른 불소이용법의 효과 및 지식도 조사연구)

  • Park, Hong-Ryurn;Ku, In-Young;Moon, Seon-Jeong
    • Journal of Korean society of Dental Hygiene
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    • v.11 no.1
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    • pp.59-68
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    • 2011
  • Objectives : To investigate the knowledge and recognition level of fluorine by teaching career among class teachers, who are primarily responsible for oral health education, despite lack of expertise in oral health, by playing a model role for students through continuous contacts with them, and provide basic elementary data about accurate knowledge and how to correctly use fluorine remarkably effective in preventing dental caries. Methods : A self-administered survey was conducted with 539 teachers at 21 elementary schools in Jinhae City from September 1 to October 15, 2010, drawing the following conclusions. Results : 1. As for the channel for acquiring knowledge of oral health, the highest frequency was found in health programs for respondents with less than 9 years of career, in dental clinics for those with 20 to 29 years of career, and in PR booklets for those with 10 to 19 years and 30 years and longer of career. 2. Use of fluorine-containing toothpaste and fluorine spread is very effective and effective in preventing dental caries got 64.9%, 72.2%, 72.3%, 77.7% and 54.0%, 63.1%, 62.2%, 69.7%, respectively, among elementary school teachers with less than 9 years, 10 to 19 years, 20 to 29 years, and 30 years and longer of career. 3. Intake of fluoride and toothbrushing with fluoric solution is very effective and effective in preventing dental caries got 33.3%, 40.1%, 39.5%, 55.3% and 50.0%, 54.9%, 48.8%, 69.7%, respectively, among elementary school teachers with less than 9 years, 10 to 19 years, 20 to 29 years, and 30 years and longer of career. 4. Use of fluoric tablets is very effective and effective in preventing dental caries got 32.9%, 36.0%, 36.1%, 47.3%, respectively, among elementary school teachers with less than 9 years, 10 to 19 years, 20 to 29 years, and 30 years and longer of career. 5. Most of the elementary school teachers knew the fact that fluorine increases dental resistance to cavity and prevents bacterial growth but gave incorrect responses to properties of becoming basic nutrients or inducing recalcification. Conclusions : Various types of application of fluorine during the elementary-level childhood experiencing the most frequent dental caries will be very useful in improving oral health in the future. It is necessary to enable class teachers to get correct recognition of fluorine through supplementary and job training based on technical knowledge and various educational materials so that they, who are directly responsible for health management through continuous contacts with students, can understand how to correctly use fluorine and get accurate knowledge.

Insecticidal Effect of an Entomopathogenic Fungus, Beauveria bassiana ANU1 to Spodoptera exigua and Plutella xylostella by Different Temperature and Humidity Conditions (파밤나방과 배추좀나방에 대한 곤충병원성 곰팡이 Beauveria bassiana ANU1의 온도와 습도조건에 따른 살충효과)

  • Lee, Jung-Bok;Park, Youngjin
    • The Korean Journal of Pesticide Science
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    • v.19 no.2
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    • pp.125-133
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    • 2015
  • Entomopathogenic fungi have been studied to develop for biological control agents as an alternative to chemical control agents in insect pest management. Two Lepidopteran insects, Spodoptera exigua and Plutella xylostella, are serious insect pests infested various crops, but not effectively controlled by commercial chemical pesticides due to its high insecticide resistance. A fungal isolate was isolated from S. exigua larvae collected from green onion field in Andong, Korea. To identify the fungal isolate, 18srRNA sequence for internal transcribed spacer (ITS) and ${\beta}$-tubulin regions were sequenced. The ITS and ${\beta}$-tubulin sequence were highly matched to Beauveria bassiana and morphological characteristics also was fit to known B. bassiana. Finally, isolated fungus has identified as B. bassiana and named B. bassiana ANU1. The result of bioassay, median lethal concentrations were $2.7{\times}10^3$ and $0.9{\times}10^3conidia/ml$ and medial lethal times were 65.6 and 60.8 h to S. exigua and P. xylostella, respectively. B. bassiana ANU1 showed high pathogenicity to two insect pests from $20^{\circ}C$ to $30^{\circ}C$ at 50% relative humidity (RH) and more than 40% RH at $25^{\circ}C$ with $10^7conidia/ml$ of concentration.

A fundamental study on the jet fan capacity for smoke control considering thermal buoyancy force in tunnel fires (터널 화재 시 열부력을 고려한 제연용 제트팬 용량산정에 관한 기초 연구)

  • Lee, Ho-Hyung;Choi, Pan-Gyu;Jo, Jong-Bok;Lee, Seung-Chul;Lee, Chang-Woo
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.20 no.2
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    • pp.501-511
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    • 2018
  • As a result of the recent revision of the 'Guideline for Installation and Management of Fire Prevention Facility in Road Tunnels', the thermal buoyancy has to be taken into account when calculating the capacity of jet fans for smoke control in tunnel fires. However, there is no detailed methodologies for considering thermal buoyancy, so further study is needed. In this study, the thermal buoyancy in the tunnel is calculated by 3-D numerical simulation to consider the thermal buoyancy in case of fire in tunnels, and the relationship between heat buoyancy and vehicle drag, And the method of calculating the capacity of the jet fan for smoke control in tunnels. According to the analysis results, heat buoyancy acts as a resistance force in the case of a down-slope tunnel, and the pressure rise of jet fan for smoke control is not simply determined by the value of heat buoyancy at the entrance of the tunnel and the value of the vehicle drag at the exit. And it is analyzed that it is necessary to carry out a comprehensive review according to the location of the fire vehicle in tunnels.

Inhibitory Activity of Garlic Fermented by Pediococcus pentosaceus KACC 91419 against Antibiotic-resistant Pathogens

  • Ham, Jun-Sang;Lee, Seung-Gyu;Kim, Min-Kyung;Oh, Mi-Hwa;Jeong, Seok-Geun;Kim, Dong-Hun;Lee, Se-Hyung;Chae, Jong-Pyo;Lee, Ji-Yoon;Kang, Dae-Kyung
    • Asian-Australasian Journal of Animal Sciences
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    • v.23 no.9
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    • pp.1236-1243
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    • 2010
  • The aim of this study was to screen lactic acid bacteria for the fermentation of garlic and to assess the increase in inhibitory activity of garlic fermented against antibiotic-resistant pathogens for use as an animal feed supplement. We screened 45 strains of lactobacillus for the fermentation of garlic. Of these strains, 23 showed similar growth rates with or without allicin. Cultures of the 23 strains were mixed with an equivalent amount of garlic juice and incubated overnight at $37^{\circ}C$. The three strains with the lowest pH values were Lactobacillus paracasei KCTC 3169, L5 strain, and L. reuteri SW. Garlic juice fermented by the L5 strain more strongly inhibited antibiotic-resistant pathogenic bacteria than L. paracasei KCTC 3169, L. reuteri SW, or garlic juice itself. By examining carbohydrate utilization, morphologic properties and 16S rRNA gene sequences, we identified the L5 strain as Pediococcus pentosaceus and deposited it in the name of P. pentosaceus KACC 91419 into the Korea Agricultural Culture Collection. To identify the antimicrobial compound from the garlic filtrate fermented by P. pentosaceus KACC 91419, we fractionated P. pentosaceus KACC 91419 culture on a C18 column and checked the antimicrobial activity of fractions A6 to A10. Only fraction A9 showed inhibitory activity on Staphylococcus aureus. Comparing the mass spectra of the fractions with and without antimicrobial activity, we observed a single dominant product ion (m/z 157.99) from the fraction showing antimicrobial activity. Its molecular mass (157.99) was 2 atomic mass units less than that of allicin (162.02). This suggests that allicin might be converted to its derivative, which has antimicrobial activity, during fermentation by P. pentosaceus KACC 91419.

Applicability of Volatile Corrosion Inhibitor and VCI Films for Conservation of Artworks (미술작품의 보존을 위한 기화성 방청제 및 방청필름의 적용성 연구)

  • Beom, Dae Geon;Han, Ye Bin
    • Journal of Conservation Science
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    • v.36 no.2
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    • pp.82-92
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    • 2020
  • Modern artworks are constructed using a variety of materials and techniques. Sculptures, which predominantly consist of metals, usually have different shapes and consist of different material mixtures. The structural and material properties of these sculptures are often controlled by conservation treatment methods. However, the application of existing treatment methods is challenging at times, indicating that more diverse treatment materials and techniques are necessary. Therefore, in this study, a treatment method that employs volatile corrosion inhibitor(VCI) powder, rather than an anti-corrosion solution, for the conservation and management of metal artworks was used. VCI powder and VCI films containing VCI powder were used, and the results obtained confirmed that both of them showed anti-corrosion effect. Only a slight change in the chromaticity of metal samples was observed, and compared to the untreated samples, the application of the VCI powder resulted in a decrease in the rate of corrosion by half. Moreover, VCI film tests revealed that comparing to the untreated or polyethylene film-treated samples, VCI film treatment resulted in a decrease in the occurrence of corrosion compounds. The contact angle, surface energy, and surface electrical resistance were measured, and the evaluation of these surface properties established the anti-corrosion effect of VCI. Additionally, direct application of VCI and VCI films on actual sculptures further confirmed the anti-corrosion effect of VCI.

Comparison of Forage Production of Annual Legume in the Central Region of Korea (중부지방에서 일년생 콩과목초의 사초 생산성 비교)

  • Kim, J.D.;Kwon, C.H.;Kim, S.G.;Park, H.S.;Ko, H.J.;Kim, D.A.
    • Journal of Animal Science and Technology
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    • v.44 no.5
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    • pp.617-624
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    • 2002
  • Annual legume is being used as an important source of protein for farm animals and an ingredient for nitrogen fertilizers. There are, however, difficulties in selecting appropriate cultivar and forage management technique. The objective of this study is to select the best performing cultivars and evaluate a forage value on annual legume at two locations (Suwon and Sunghwan) for 1 year (1999${\sim}$2000). All cultivars shown a seedling vigor and lodging resistance of 8 rating or higher. Crimson and rose clover showed that they are appropriate for overwintering, but ;Laser; (35.9%) and 'Nitro'(9.1%) of persian clover variety did not overwinter well from 1999 to 2000. Flower stage was observed 4th of May for 'Tibbee', 6th of May for 'Contea' crimson clover, and 29th of April for 'Bolta balansa' rose clover. DM yield of a crimson clover 'Contea' (4,218kg/ha) was the highest among the legume forage. A crimson clover 'Tibbee' and rose clover 'Bolta balansa' also had a high production yield (3,874 and 3,828kg/ha). Calculations of relative feed value (RFV) based on the acid and neutral detergent fiber (ADF and NDF) of annual legume were over 125, which means that quality was high. According to the results of this study, crimson and rose clovers are recommended due to their high winter survival rate and high DM yield. Persian clover is not recommended because of a low overwintering rate at the Central region in Korea.