• Korean Journal of Computational Design and Engineering
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• v.18 no.6
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• pp.439-450
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• 2013

In the case of a floating offshore structure such as FPSO(Floating, Production, Storage, and Offloading unit), many equipment should be installed in the limited space, as compared with an onshore structure. Recently, the requirement for an optimal layout method of the structure has been raised. Thus, a layout method of the floating offshore structure was proposed in this study. First, an optimization problem for layout design was mathematically formulated, and then an optimization algorithm was implemented based on the genetic algorithm in order to solve it. To evaluate the applicability of the proposed method, it was applied to examples ofFPSO topsides and an offshore wind turbine. As a result, it was shown that the proposed method can be applied to layout design of the floating offshore structure.

• Biomolecules & Therapeutics
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• v.30 no.1
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• pp.48-54
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• 2022

GPR43 (also known as FFAR2), a metabolite-sensing G-protein-coupled receptor stimulated by short-chain fatty acid (SCFA) ligands is involved in innate immunity and metabolism. GPR43 couples with Gα_i/o and Gα_q/11 heterotrimeric proteins and is capable of decreasing cyclic AMP and inducing Ca²⁺ flux. The GPR43 receptor has additionally been shown to bind β-arrestin 2 and inhibit inflammatory pathways, such as NF-κB. However, GPR43 shares the same ligands as GPR41, including acetate, propionate, and butyrate, and determination of its precise functions in association with endogenous ligands, such as SCFAs alone, therefore remains a considerable challenge. In this study, we generated novel synthetic agonists that display allosteric modulatory effects on GPR43 and downregulate NF-κB activity. In particular, the potency of compound 187 was significantly superior to that of pre-existing compounds in vitro. However, in the colitis model in vivo, compound 110 induced more potent attenuation of inflammation. These novel allosteric agonists of GPR43 clearly display anti-inflammatory potential, supporting their clinical utility as therapeutic drugs.

• ETRI Journal
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• v.36 no.5
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• pp.841-846
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• 2014

This study proposes a novel optical sensor structure based on a refractometer combining a bend waveguide with an air trench. The optical sensor is a $1{\times}2$ splitter structure with a reference channel and a sensing channel. The reference channel has a straight waveguide. The sensing channel consists of a U-bend waveguide connecting four C-bends, and a trench structure to partially expose the core layer. The U-bend waveguide consists of one C-bend with the maximum optical loss and three C-bends with minimum losses. A trench provides a quantitative measurement environment and is aligned with the sidewall of the C-bend having the maximum loss. The intensity of the output power depends on the change in the refractive index of the measured material. The insertion loss of the proposed optical sensor changes from 3.7 dB to 59.1 dB when the refractive index changes from 1.3852 to 1.4452.

• Journal of the Korean Society for Precision Engineering
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• v.33 no.4
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• pp.317-324
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• 2016

Stress tests were conducted in the carbody of the railroad car to check the structural strength of the body of the railroad car. The objective of this study was to evaluate safety of the carbody of a railroad car under the maximal strength. The carbody of rolling stock is a principal structure that supports major equipment of the underframe and the freight. Therefore, the strength evaluation of this structure is important. This study was carried out to analyze the structure of carbody and evaluate safety under maximum vertical load, compressive load, and torsional load. Accordingly, stress tests were conducted on the carbody to measure the stress on each of their parts. Before the load test, a structural-analysis program was used for the stress distribution analysis of the body structure.

• Proceedings of the KSRS Conference
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• 2004.10a
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• pp.673-676
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• 2004

To manage and query moving objects efficiently in MMDBMS, a memory index structure should be used. The most popular index structure for storing trajectories of moving objects is 3DR-tree. The 3DR-tree also can be used for MMDBMS. However, the volume of data can exceed the capacity of physical memory since moving objects report their locations continuously. To accommodate new location reports, old trajectories should be migrated to disk or purged from memory. This paper focuses on migration policies of a main memory index structure. Migration policies consist of two steps: (i) node selection, (ii) node placement. The first step (node selection) selects nodes that should be migrated to disk. The criteria of selection are the performance of insertion or query. The second step (node placement) determines the order of nodes written to disk. This step can be thought as dynamic declustering policies.

• THE INTERNATIONAL COMMERCE & LAW REVIEW
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• v.35
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• pp.147-178
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• 2007

This study clarified a study of relationship of strategic alliance structure factor, partner selection criteria and performance awareness on the container liners alliance. In order to obtain such objective of study existing literature variables suitable to the container liner were perused and extracted. Research models for research development and three study hypothesis were set out and scope of investigation and samples were chosen. The research hypothesis are followings. H1: The factors of strategic alliance motivation influence the performance awareness. H2: The strategic alliance structure factors influence the performance awareness. H3: The factors of partner selection criteria influence the performance awareness. In the result of the empirical study, the hypothesis 1, hypothesis 2 were supported completely and hypothesis 3 was partially supported.

• Journal of the Korea Institute of Building Construction
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• v.11 no.5
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• pp.515-522
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• 2011

As Construction and Demolition (C&D) debris increases every year, systems have been adopted to compel the use of recycled aggregate made from C&D debris, and the use of recycled aggregate in the construction field has increased. But environmental problems linked to the alkalinity of recycled aggregate have occurred, and a study on approaches to lower the alkalinity of recycled aggregate is needed. It was certified by this study that a large amount of recycled aggregate could be carbonated in the C&D debris midterm-treatment field. As a result, the density and the water absorption of recycled aggregate after carbonation reaction was improved, and pH of recycled aggregate was lowered from over 11 to 9.4. X-ray Diffraction (XRD), Scanning Electron Microscope (SEM), Energy Dispersive Spectroscopy (EDS), and Thermogravimetry/Differential Thermal Analysis (TG/DTA) methods also indicated the carbonation of recycled aggregate.

• Steel and Composite Structures
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• v.44 no.2
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• pp.211-224
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• 2022

Multi-objective optimization was conducted to obtain the optimal configuration of a composite sandwich structure with honeycomb-foam hybrid core subjected to underwater shock waves, which can fulfill the demand for light weight and energy efficient design of structures against underwater blast. Effects of structural parameters on the dynamic response of the sandwich structures subjected to underwater shock waves were analyzed numerically, from which the correlations of different parameters to the dynamic response were determined. Multi-objective optimization of the structure subjected to underwater shock waves of which the initial pressure is 30 MPa was conducted based on surrogate modelling method and genetic algorithm. Moreover, optimization results of the sandwich structure subjected to underwater shock waves with different initial pressures were compared. The research can guide the optimal design of composite sandwich structures subjected to underwater shock waves.

• Nuclear Engineering and Technology
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• v.55 no.12
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• pp.4307-4316
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• 2023

In this paper, modal effective mass for asymmetric fluid-structure interaction system is defined and equations for its calculation is derived. To establish consistency, modal effective mass in symmetric structure only system is briefly reviewed, followed by a definition of the modal effective mass in asymmetric system. The equations for calculating modal effective mass in asymmetric system are derived by utilizing the properties of left and right eigenvectors. To simplify the equations, the assumption is made that the mass matrix is only affected by the fluid. The simplified equation is then compared to the equation already used in ANSYS. Finally, the validity of the modal effective mass definition and derivation in this paper is demonstrated through a simple example.

• Journal of Science of Art and Design
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• v.6
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• pp.203-225
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• 2004

We are sure that Abakanowicz positively assumes a position of members, which are represented the later modern fabric design. In sprite of his pervasive evaluation, we have doubt about his achievement because the preceding research is insufficient about argumentsuch as dependence on intuitive emotion study, conventional analysis of structure and insufficient inquiry of causa efficiens. We agree that basic structure of is dissipation. Though right and left symmetrical structure is similar, also that structure is different. We can't decide whether structure is unification structure, difference structure or mixture structure . We think that the time of confusing argument of his structure is changing period for disorganization trend. The result of this study confirm the research possibility about space organization with restructure analysis and verification for examining essence structure of sample text . The Thesis are concern that the different between paradigmatic appearances and syntagmatic, which exist . So, we can approach the meaning of system and find dominent point about constructional relationship on the works. The meaning of dominent point is understood about sexless trend or Androgyne, which are appeared Abakanowicz forth work period. The relationship structure which is mixed both issue show that inner issue of work is located the highest position. The paper presents confusing manufacture system, which are suggested man-woman sex and mixed meaning. The other result of this study are, 1. being known as Abakan algorism, Abakanowicz has new drafting idiom from his ancient belief. 2. we need to research the body texture of Abakanowicz with the trend of restructure of body study. 3. we need argue about gender study in relative with poster moderntheology related problem of sexlessness people and perfect sex-people.