• 제목/요약/키워드: research products

검색결과 14,229건 처리시간 0.041초

Anti-angiogenic and anti-tumor activity of 2′ -hYdroxy-4′ -methoxychalcone

  • Jung, Sang-Hoon;Lee, Yeon-Sil;Lee, Sang-Hyun;Lim, Soon-Sung;Kim, Yeong-Shik;Shin, Kuk-Hyun
    • 대한약학회:학술대회논문집
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    • 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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    • pp.359.2-359.2
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    • 2002
  • In the previous study, we reported that 2'-hydroxy-4'-methxoychalcone, synthetic chalcone inhibited PGE2 production in TPA- stimulated rat peritoneal macrophages by inhibiting the induction of COX-2 protein. The present study was carried out to clarify whether 2'-hydroxy-4'-methoxychalcone inhibit angiogenesis by the experimental methods in vitro and in vivo. 2'-Hydroxy-4'-methoxychalcone decreased angiogenesis of both chick embryos in the chorioallantoic membrane assay and basic fibroblast growth factor-induced vessel formation inthe mouse Martigel plug assay. (omitted)

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Determination of Sulfur Dioxide in Herb Drugs

  • Ko, Suk-Kyung;Seung, Hyun-Jeung;Yu, In-Sil;Kim, Hwa-Soon;Park, Noh-Woon;Kang, Hee-Gon
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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    • pp.103.1-103.1
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    • 2003
  • This study was carried out to investigate sulfur dioxide in herb drugs.(Puerariae Radix, Lycii Fructus, Platycodi Radix, Dioscoreae Rhizoma, Mori Radicis Cortex, Nelumbo Seed, Paeoniae Radix, Remotiflori Radix, Astragali Radix, Polygonatum Rhizome) Experimental subjects included 105 cases of 10 species of herb drugs collected in Kyung-dong market from December in 2001 to February in 2002. Sulfur dioxide was determined by Optimized Monier-Wiliams method. In 65 cases(61.9%) of the 105 cases, we detected $SO_2$ over 10mg/kg. (omitted)

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Platelet Anti-aggregating Triterpene and Sterol Constituents from the Leaves of Acanthopanax senticosus

  • Jin, Jing-Ling;Lee, Sang-Hyun;Lee, Yong-Yook;Kim, Jeong-Mi;Heo, Jung-Eun;YunChoi, Hye-Sook
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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    • pp.206.1-206.1
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    • 2003
  • From methanol extract of Acanthopnanax senticosus, six platelet anti-aggregating compounds, chiisanogenin (1), chiisanoside (2), ursolic acid (3), oleanolic acid (4), b-sitosterol (5) and daucosterol (6) were isolated. All of the isolated compounds showed dose-dependent inhibitory activities to rat platelet aggregation induced by all the agonist employed. Compound 1 showed about 50 folds higher potency than acetylsalicylic acid (ASA) on U46619 induced platelet aggregation (IC$\sub$50/ : 6.21 ${\mu}$M) and 10 ∼ 20 folds higher effect than ASA on epinephrine and arachidonic acid (AA) induced aggregation (IC$\sub$50/ ; 2.50 and 4.81 ${\mu}$M, respectively). (omitted)

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Constituents from the roots of Hemerocallis fulva

  • Kim, Ju-Sun;Sik, Kang-Sam;Ho, Son-Kun;Wook, Chang-Hyeun;Kim, Hyun-Pyo;Bae, Ki-Hwan
    • 대한약학회:학술대회논문집
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    • 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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    • pp.196.1-196.1
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    • 2002
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Developing a Web-based System for Computing Pre-Harvest Residue Limits (PHRLs)

  • Chang, Han Sub;Bae, Hey Ree;Son, Young Bae;Song, In Ho;Lee, Cheol Ho;Choi, Nam Geun;Cho, Kyoung Kyu;Lee, Young Gu
    • Agribusiness and Information Management
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    • 제3권1호
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    • pp.11-22
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    • 2011
  • This study describes the development of a web-based system that collects all data generated in the research conducted to set pre-harvest residue limits (PHRLs) for agricultural product safety control. These data, including concentrations of pesticide residues, limit of detection, limit of quantitation, recoveries, weather charts, and growth rates, are incorporated into a database, a regression analysis of the data is performed using statistical techniques, and the PHRL for an agricultural product is automatically computed. The development and establishment of this system increased the efficiency and improved the reliability of the research in this area by standardizing the data and maintaining its accuracy without temporal or spatial limitations. The system permits automatic computation of the PHRL and a quick review of the goodness of fit of the regression model. By building and analyzing a database, it also allows data accumulated over the last 10 years to be utilized.

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Sesquiterpene Components from the Flower Buds of Magnolia fargesii

  • Jung, Keun-Young;Kim, Dong-Seon;Oh, Sei-Ryang;Lee, Im-Seon;Lee, Jung-Joon;Lee, Hyeong-Kyu;Shin, Dong-Hyuk;Kim, Eun-Hee;Cheong, Chae-Joon
    • Archives of Pharmacal Research
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    • 제20권4호
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    • pp.363-367
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    • 1997
  • From the Chinese crude drug shin-i, the flower buds of Magnolia fargesii, four sesquiterpene, oplopanoe (1), oplodiol (2), homalomenol A (3) and $1{\beta},4{\beta},7{\alpha}$-trihydroxyeudesmane (4) were isolated. These structures were elucidated and the ${13}^C-NMR$ chemical shifts of these compounds were revised by means of various 2D-NMR techniques.

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