• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2005년도 추계종합학술대회
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• pp.171-174
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• 2005

The circuit simulation analysis and diagnosis methods are used to instruments in detail when they give apparently abnormal readings. In this paper, a new simulator through an analysis of the important circuits modeling under severe accident conditions has been designed, the realization for a body work instead of the two sorts of the Labview & Pspice as an one order command in the Labview program. The program can be shown the output graph form the circuit modeling as an order commend. The procedure for the simulator design was divided into two design steps, of which the first step was the diagnosis methods, the second step was the circuit simulator for the signal processing tool. It has three main functions which are a signal processing tool, an accident management tool, and an additional guide from the initial screen.

• 한국연초학회지
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• 제35권1호
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• pp.20-27
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• 2013

An Electronic Nose(E-Nose) and Gas Chromatography/Mass Spectroscopy (GC/MS) are meanwhile conventional technique to analyze volatile materials in many industries (e.g., food, medicine, environment) and have broad acceptance in the analysis of tobacco products. In this study, an experiment where tin oxide gas sensor array responses and GC/MS profiles are used to characterize the volatile compounds of different cigarettes at the same time is performed and the measurements of two instruments are compared for cigarette samples with a known chemical information. E-Nose and GC/MS were employed to differentiate and match flavored cigarettes with commercial tobacco flavoring agents (lavender, vanilla, peppermint, orange, star anise). For verifying reliability of two systems, the analyses were conducted in terms of amount of flavors in each cigarettes using partial least squares (PLS) and with the principal components analysis (PCA). Various chemical sensors and GC/MS data was reduced into two principal factors (PC1, PC2) for being distinguished with visualized regions. Both systems provided adequate results for odor characteristics of cigarettes in this study with each instrument having its own advantages and disadvantages.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2007년 가을학술발표회
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• pp.465-477
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• 2007

Recently a number of research has been performed for the combination of new high technologies in order to find the solutions for various problems in civil engineering research field. Various high-tech measuring instruments have been applied to the geotechnical engineering field, and many attempts have also been performed for the more accurate measurements. Especially, the researches using image on the digital photogrammetry technique are gradually extending nowadays. The computer program developed using the digital photogrammetry technique and the case studies are explained and presented in this paper. Therefore, it could be considered that not only the measurement with high-accuracy but the disaster prevention should be available through the practical use of digital photogrammetry technique. The applicability would also be increased in the measurement of both the geotechnical engineering field as well as other research fields.

• 한국안전학회지
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• 제32권2호
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• pp.124-131
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• 2017

This study aims to contribute to urban policy for more effective disaster prevention, as abnormal natural disasters are becoming more frequent. Up to now, the urban plan for disaster prevention in Korea merely includes basic principles and necessities of measures as an early stage. Furthermore, there are difficulties to make specific programs because the legal system, technical instruments, and financial supports are not sufficient. Therefore, this study figures out problems in the current plan related to urban prevention after analyzing the legal system and practices. Resulting from case studies in developed countries, the study draws significant implications, as follows: enhancing legally binding force; improving the procedures for the programs; establising technical infrastructure. It first suggests a way for the urban policy for disaster prevention by considering our local features comprehensively. It then defines the roles of central, local governemnts and research institutions, and the procedure for urban disaster prevention planning building on the individual roles. This study concludes that an emphasis should be placed on institutional tools necessary to publish technical guideline and establish the system so that urban planners more easily access to disaster risk information.

• Biomolecules & Therapeutics
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• 제19권1호
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• pp.1-8
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• 2011

G-protein coupled receptors (GPCRs) constitute an important class of drug targets and are involved in every aspect of human physiology including sleep regulation, blood pressure, mood, food intake, perception of pain, control of cancer growth, and immune response. Radiometric assays have been the classic method used during the search for potential therapeutics acting at various GPCRs for most GPCR-based drug discovery research programs. An increasing number of diverse small molecules, together with novel GPCR targets identified from genomics efforts, necessitates the use of high-throughput assays with a good sensitivity and specificity. Currently, a wide array of high-throughput tools for research on GPCRs is available and can be used to study receptor-ligand interaction, receptor driven functional response, receptor-receptor interaction,and receptor internalization. Many of the assay technologies are based on luminescence or fluorescence and can be easily applied in cell based models to reduce gaps between in vitro and in vivo studies for drug discovery processes. Especially, cell based models for GPCR can be efficiently employed to deconvolute the integrated information concerning the ligand-receptor-function axis obtained from label-free detection technology. This review covers various platform technologies used for the research of GPCRs, concentrating on the principal, non-radiometric homogeneous assay technologies. As current technology is rapidly advancing, the combination of probe chemistry, optical instruments, and GPCR biology will provide us with many new technologies to apply in the future.

• 근관절건강학회지
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• 제21권3호
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• pp.255-264
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• 2014

Purpose: The purpose of the study were to analyze the research trends of compassion fatigue in Korea nurses and to suggest future research directions. Methods: For this study, RISS, KISTI, KISS, National Assembly Library databases were searched using the key words 'compassion fatigue', 'secondary traumatic stress', 'professional quality of life' that contains compassion fatigue as a sub-element, and 'nurses' for this study. A total of 124 articles published in June 2014 were searched and analyzed 19 articles for the final analysis. Results: The most frequently used study design was descriptive (N=17, 89.5%). High compassion fatigue was reported in this study. Factors affecting compassion fatigue were personal factors (e.g., age, health state, and sleep hours), work-related factors (e.g., experience with traumatized patients), and psychological factors (e.g., job stress, anxiety, excessive empathy, social support, and coping strategy). Finally, Consequence factors of compassion fatigue was reported burnout, silencing response and turnover intention. Conclusion: There was a few studies on compassion fatigue. Further research on compassion fatigue needs to use a variety of study designs instruments suitable for Korean nurses, and to develop management programs on compassion fatigue in nurses.

• Nuclear Engineering and Technology
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• 제46권2호
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• pp.273-280
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• 2014

The spectrum weighted responses of various detectors were calculated to provide guidance on the proper selection and use of survey instruments on the basis of their energy response characteristics on the neutron fields. To yield the spectrum weighted response, the detector response functions of 17 neutron-measuring devices were numerically folded with each of the produced calibration neutron spectra through the in-house developed software 'K-SWR'. The detectors' response functions were taken from the IAEA Technical Reports Series No. 403 (TRS-403). The reference neutron fields of 21 kinds with 2 spectra groups with different proportions of thermal and fast neutrons have been produced using neutrons from the $^{241}Am$-Be sources held in a graphite pile, a bare $^{241}Am$-Be source, and a DT neutron generator. Fluence-average energy ($E_{ave}$) varied from 3.8 MeV to 16.9 MeV, and the ambient-dose-equivalent rate [$H^*(10)/h$] varied from 0.99 to 16.5 mSv/h.

• Nuclear Engineering and Technology
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• 제40권4호
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• pp.311-318
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• 2008

In modem power reactors, nuclear fuels have recently reached 55,000 MWd/MtU from the initial average burnup of 35,000 MWd/MtU to reduce the fuel cycle cost and waste volume. At such high burnups, a fuel pellet produces fission products proportional to the burnup and creates a typical high burnup structure around the periphery region of the pellet, producing the so called 'rim effect'. This rim region of a highly burnt fuel is known to be ca. $200\;{\mu}m$ in width and is known to affect the fuel integrity. To characterize the local burnup in the rim region, solid sampling in the micro meter region by laser ablation is needed so that the distribution of isotopes can be determined by ICP-MS. For this procedure, special radiation shielding is required for personnel safety. In this study, we installed a radiation shielded laser ablation ICP-MS system, and a performance test of the developed system was conducted to evaluate the safe operation of instruments.

• Journal of Preventive Medicine and Public Health
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• 제52권5호
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• pp.281-291
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• 2019

Objectives: The validity of instruments measuring socioeconomic position (SEP) has been a major area of concern in research on cardiovascular health disparities. The purpose of this systematic review is to identify the current status of the methods used to measure SEP in research on cardiovascular health disparities in Korea and to provide directions for future research. Methods: Relevant articles were obtained through electronic database searches with manual searches of reference lists and no restriction on the date of publication. SEP indicators were categorized into compositional, contextual, composite, and life-course measures. Results: Forty-eight studies published from 2003 to 2018 satisfied the review criteria. Studies utilizing compositional measures mainly relied on a limited number of SEP parameters. In addition, these measures hardly addressed the time-varying and subjective features of SEP. Finding valid contextual measures at the organizational, community, and societal levels that are appropriate to Korea's context remains a challenge, and these are rarely modeled simultaneously. Studies have rarely focused on composite and life-course measures. Conclusions: Future studies should develop and utilize valid compositional and contextual measures and appraise social patterns that vary across time, place, and culture using such measures. Studies should also consider multilevel influences, adding a focus on the interactions between different levels of intertwined SEP factors to advance the design of research. More attention should be given to composite and life-course measures.

• 센서학회지
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• 제32권6호
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• pp.412-417
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• 2023

There is increasing interest in the rapid and highly sensitive monitoring of cell viability in biological and toxicological research. Conventional methods depend on optical assays using Water Soluble Tetrazolium-8 (WST-8) or 3-(4,5-dimethylthiazolyl-2)-2,5-diphenyltetrazolium bromide (MTT) assay, which requires a large volume of samples and special instruments, necessitating shipment of clinical samples to laboratories. This paper reports on the development of a rapid and sensitive electrochemical (EC) sensor using screen printed electrode (SPE) and surface modification using 4'-mercapto-N-phenylquinone diamine (4'-NPQD), as double electron mediators, for monitoring cell viability via the measurement of nicotinamide adenine dinucleotide (NADH). We used the sensor to observe the viability of MCF-7 and doxorubicin (Dox)-treated cells. The oxidation current of NADH was measured via chronoamperometry (CA), and the EC results showed a good linear relationship when compared with NADH quantification using WST-8 assay. The analysis time was only 10 s and limit of detection (LOD) of NADH was 1.78 µM. Our EC method has the potential to replace conventional WST assays for cell viability and cytotoxicity experiments.