• Clinical and Experimental Vaccine Research
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• v.13 no.2
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• pp.91-104
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• 2024

This narrative review describes genomic characteristic, serotyping, immunogenicity, and vaccine development of Streptococcus pneumoniae capsular polysaccharide (CPS). CPS is a primary virulence factor of S. pneumoniae. The genomic characteristics of S. pneumoniae CPS, including the role of biosynthetic gene and genetic variation within cps (capsule polysaccharide) locus which may lead to serotype replacement are still being investigated. One hundred unique serotypes of S. pneumoniae have been identified through various methods of serotyping using phenotypic and genotypic approach. The advantages and limitations of each method are various, emphasizing the need for accurate and comprehensive serotyping for effective disease surveillance and vaccine targeting. In addition, we elaborate the critical role of CPS in vaccine development by providing an overview of immunogenicity, ongoing research of pneumococcal vaccines, and the impact on disease burden.

• 한국디지털정책학회:학술대회논문집
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• 2003.12a
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• pp.101-114
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• 2003

In industrialised countries, innovation is a key source of economic growth. Research is a key driver of technological innovation and involves the process of systematic investigation and/or experimentation to discover new knowledge. The Governments' industry innovation policy supports a business focus on Research and Development (R&D) through a range of programs in order to achieve these aims. The Innovation Statement, launched by the Australian Prime Minister in January 2001, commits an additional $3 billion over five years to encourage and support innovation. The Australian Government aims to build world competitive firms and strong research capability in industry to strengthen Australia's international competitiveness and increase national prosperity. It develops policies and programs to enhance investment in innovation. The Australian Government also undertakes analysis and comparisons of innovation policies, instruments and approaches to maintain a leading-edge National Innovation System. This includes analysis of the innovation activities of other nations, and evaluation of the impacts of innovation policies and programs on Australia's institutions and enterprises. This paper examines Australia's Innovation policies, Backing Australian Ability.

• STI Policy Review
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• v.3 no.1
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• pp.117-138
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• 2012

Governments around the world place great hopes in innovation in their search for new sources of growth and for responses to grand challenges, such as climate change, new or re-emerging infectious diseases, accelerating urbanisation, ageing, food security, and availability of clean water. However they must devise their relevant support policies -- including through sponsored research within public research institutes -- taking into account that innovation processes are currently undergoing a major transformation. New innovation patterns include a broadening scope of relevant activities, a growing importance but changing nature of scientific roots of technological development, a stronger demand-pull, the emergence of new local and national STI powerhouses, and the rise of more open and globalised innovation networks. They translate into new opportunities but also constraints for policies to enhance the contribution of public research institutes to national innovation performance. The article derives the main policy implications regarding the desirable evolution of the mission, research focus, as well as the funding and steering of public research institutes, with a special reference to Korea.

• Journal of Technology Innovation
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• v.14 no.2
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• pp.167-181
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• 2006

This paper reviews regional innovation policy in Japan. 'Technopolis' policy, the first technology-based regional development policy in the world, was implemented in Japan. Nonetheless, technology-based regional endogenous development did not occur. Then, regional technology transfer was pursued. In order to make use of universities and public research institutes in a region for development, university-industry collaboration and cross-over, such as university spin-offs, were promoted. Within this background, new technology-based regional development policies have been introduced based on a cluster approach. These policies are the knowledge cluster Initiative and the industrial cluster program. However, existing companies have difficulty in carrying out innovation. This paper argues that a cluster to create new start-ups that carry out innovation is also needed and explains a new concept of venturing cluster. Based on this new cluster concept, this paper analyzes the situation of Sapporo in Japan, where many university spin-offs are being created in the biotechnology field.

• Asian Journal of Innovation and Policy
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• v.8 no.3
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• pp.325-342
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• 2019

Gendered innovation in Science, Technology and Innovation, which seeks better science for both men and women by integrating sex and gender analysis, has become an important issue in the entire process of STI, as initiated by the European Commission, Canadian Institutes of Health Research in Canada and the National Institutes of Health in the United States. Korea has also attempted to reflect gendered innovations in Science and Technology as a critical factor in the 3rd and 4th National Plan, followed by the Act on Women Scientists and Engineers (2002). Against this background, the aim of this study is to prioritize the policy instruments regarding gendered innovation in Research and Development. Through the Focus Group Interview (FGI) and the Analytic Hierarchy Process (AHP), this study attempts to set the priority among selected criteria, various types of policy instruments, and the applied research development area. As a result, this study shows the preparation of the relevant legal and institutional mechanisms for the full introduction of gendered innovation in S&T, and the importance of various policy instruments for S&T innovation in the fields of planning, budgeting, managing national R&D projects, evaluating and impact assessment, etc., being derived in a systematic way to ensure their effectiveness.

• World Technopolis Review
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• v.8 no.2
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• pp.104-119
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• 2019

Innovation clusters are essential in the economic development of many developed countries across the world. While they present ways for under-developed and developing countries to grow their economies, fully operational innovation clusters are yet to be established in Nigeria. Many experts argue that learning from experience is an effective way of galvanizing economic development. Therefore, in this study, an empirical analysis involving a multi-variable quantitative analysis was used to examine the factors that influence the performance of the Daedeok Innopolis Innovation Cluster (South Korea). The results obtained show that the investment in education, Research and Development (R&D), labor capacity of key players within the innovation cluster, and the transfer of technology (within the cluster) were essential factors that influence the performance of the Daedeok Innopolis Innovation Cluster.

• Journal of Information Technology Applications and Management
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• v.20 no.3_spc
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• pp.279-293
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• 2013

In general, researchers, policymakers, and practitioners consider innovation by producers as a primary mode in a market economy. However, the recent research has shown that some of the most important, novel products and processes have been developed by users-both user firms and individual end-users. According to von Hippel [1988], he found that they were the developers who made about 80 percent of the most important scientific instrument innovations as well as the major innovations in semiconductor processing. In this research, we conducted grounded research on user-led innovation at the corporate-level. Also, we analyzed the train development project (SR000) of Seoul Metropolitan Rapid Transit Corporation (SMRT). We focused on identifying the success factors of user-led innovation, and development process.

• Asian Journal of Innovation and Policy
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• v.11 no.2
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• pp.258-276
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• 2022

The historical aspects, policies, institutions, awards and measurement results of scientific literacy and scientific culture development in Indonesia have currently attracted further exploration. This paper utilizes secondary data research, further analyzed by employing the Supplementary Analysis technique. The results revealed that the tradition of writing and publishing scientific journals in Indonesia has existed ever since the Dutch East Indies with the journal's publication entitled 'Natuurkundig tijdschrift voor Nederlandsch Indië' in 1850. To date, Indonesia has owned 5,990 nationally accredited journals. Policy support has been provided at the national and regional levels, despite limitations in cultivating literacy and reading habit. From the institutional perspective, Indonesia provides a wide array of public support, including the effort of the Ministry of Education and Culture for advocating the national literacy movement and the availability of a reference database and scientific access established by the National Library; the Indonesian Institute of Sciences, and the Ministry of Research and Technology. Similarly, in the award-related perspective, the Indonesia government has granted awards to individuals or groups and local governments engaging in the cultivation of scientific literacy and scientific culture. However, among the global measurements for literacy development in Indonesia (in 2020) recorded that three indicators scored less than those in 2019.

• Asian Journal of Innovation and Policy
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• v.11 no.1
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• pp.87-109
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• 2022

The study attempts to examine the system-building activities of scientific institutions in developing the Molecular Diagnostic (MDs) Innovation System in India. Scientific Institutions are the precursor of any technological development with their capabilities in generating new ideas. MDs are advanced and accurate diagnostic technology with considerable scope to serve the diagnostic needs and requirements of the healthcare system. We adopted a System framework and analyzed the development of MDs in terms of the Technological Innovation System (TIS) functions, and the systematic challenges are assessed through the System Failure Framework (SFF). Based on the secondary and primary survey of prominent science base actors, the study finds that the role of government is crucial for facilitating technological development within a science base through the mobilization of resources. In India, the MDs technological development gained significant momentum over the last decade with the development of specialized human resources and dedicated research institutes. However, we do find that the innovative capabilities in attaining need-based TIS are sub-optimal owning to the specific diagnostic needs of highly burdened diseases in the society. The system analysis reveals that the TIS functions are underperforming because of the absence of a well-defined funding mechanism and goal-oriented targeted policy regime of the government. Since MDs have a transformative effect on the present healthcare system, we argue that the government has to address the system-based challenges and issues for developing a need-based technological innovation system for MDs in the country.

• Proceedings of the Korea Technology Innovation Society Conference
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• 2006.11a
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• pp.15-41
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• 2006

The increasing popularity of the concept of technology innovation has been driven by greater international competition in a rapidly globalizing economy. Both countries and enterprises are placing more and more emphasis on it in order to gain competitive advantages. This article gives a general introduction about the research and application of technology innovation in China. At the national level, one obvious fact is that the total R&D expenditure increased rapidly during the year 2001 to year 2005 and reached Y 245 billions, and China made 2,452 international patent applications in 2005 and became the world's 10th largest user of the Patent Cooperation Treaty. At the industry and enterprise level, much progress has also been made in China. This article uses the high-tech industry as an example to introduce the industry and enterprise technology innovation respectively. Corresponding to the practice, scholars also did a great amount of research work related to technology innovation. This article sums up all the work done from the macroscopic aspect (such as national technology innovation strategy, regional innovation system, industry technology innovation) and microcosmic aspect (such as enterprise technology innovation strategy, patterns and evaluation standards). Based on the analysis, this article discusses the limitation of current work and research trend about the technology innovation.