• Journal of Microbiology
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• v.42 no.3
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• pp.216-222
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• 2004

In a previous paper, the ogdH gene that encodes 2-oxoglutarat dehydrogenase was isolated from Salmonella typhimurium. The catalytic N-terminal region in the enzyme was found to be very specific for the Salmonella species. Therefore, the aim of the present study was to detect S. typhimurium in food sources using primers designed for OGDH-l and OGDH-2 which were based on the salmonella-specific region of the ogdH gene. A simple polymerase chain reaction (PCR) detection method was developed to detect low numbers of S. typhimurium in a chicken meat microbial consortium. Using the ogdH-specific primers under stringent amplification conditions and for gene probe analysis, fewer than 100 colony-forming units (CFUs) were detectable when pure cultures were employed. When the PCR assay was run on S. typhimurium-contaminated meat contents, only the positive meat samples containing as few as 200 CFUs reacted to the assay. The method employed for sample processing is simple and it was determined to provide a sensitive means of detecting trace amounts of S. typhimurium-specific sequences in the presence of mixed meat microbial populations. When compared with six representative intestinal gram-negative bacterial strains in foods, including Vibrio parahaemolyticus, V. vulnificus, Enterobacter cloacae, E. coli O157:H7, Pseudomonas aeruginosa, and Proteus sp., S. typhimurium had a unique and distinct PCR product (796 bp). In conclusion, the two OGDH primers were found to be rapid and sensitive detectors of Salmonella spp for the PCR method.

• Proceedings of the Korea Inteligent Information System Society Conference
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• 2001.01a
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• pp.378-382
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• 2001

The purpose of this study was to develop an expert system supporting the diagnosis of diffuse interstitial lung disease by high resolution computed tomography. CLIPS(C language integrated production system) with rule-based reasoning was used to develop the system. Development of expert system had three stages knowledge acquisition, knowledge representation, and reasoning. Knowledge was obtained and integrated, from tables and figure legends of a representative textbook in the domain of this expert system, High-Resolution CT of the Lung, by Webb WR, Mueller NL, and Naidich DP. The acquired knowledge was analyzed to form a knowledge base. Overlapping knowledge was eliminated, similar pieces of knowledge were combined and professional terms were defined. The most important knowledge of findings was then selected for each disease. After groupings of combined findings were made, disease groups were analyzed sequentially to determine final diagnoses. The system was based upon the input of 69 diseases, 185 findings, 73 conditions, 387 status, and 62 rules. The system was set up to determine the diagnoses of diseases from the combination of findings using forward reasoning. In an empirical trial, the system was applied to support the diagnosis of 40 cases of diffuse interstitial lung diseases. The performance of two doctors with support of the system was compared to that of another two doctors without support of the system. The two doctors with the support of the system made more accurate diagnoses than the doctors without the support of the system. The system is believed to be useful for the diagnosis of rare diseases and for cases with many possible differential diagnoses. In conclusion, an expert system supporting the high resolution computed tomographic diagnosis of diffuse interstitial lung disease was developed and the system is thought to be useful for medical practice.

• Proceedings of the Korean Geotechical Society Conference
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• 2010.09a
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• pp.790-799
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• 2010

The Upper Devonian Grossmont Formation in Alberta, Canada reserves an estimated 50 billion cubic meters of bitumen and possess about 1/6 of the total bitumen resources in northern Alberta. However, unlike the overlying Athabasca oil sands, non conventional bitumen resources has not been developed as yet. The carbonate rocks of Grosmont Formation have been subject to various stages of diagenesis, including dolomatization and karstification with a strong effect on the distribution of porosity and permeability, which resulted in highly heterogeneous reservoirs. An extensive fracture logging and mapping was performed on total of six boreholes located in the study area to explore the characteristics of fracture geometry system and the subsurface structures of carbonates reservoir that holds bitumen. Fractal dimension was used as a measure of the statistical homogeneity of the fractured rock masses. The applicability of random Cantor dust, Dc, as a fractal parameter was examined systematically. The statistical homogeneity of fractured carbonates rock masses was investigated in the study area. The structural domains of the rock masses were delineated depthwise according to estimated Dc. The major fracture orientation was dominated by horizontal beddings having dip of $0-20^{\circ}$. Also, fractures having high dip angles existed with relatively low frequency. Three dimensional fracture network modeling for each structural domain has been performed based on fracture orientation and intensity, and some representative conceptual models for carbonates reservoir in the study area has been proposed. The developed subsurface conceptual models will be used to capture the geomechanical characteristics of the carbonates reservoir.

• The KIPS Transactions:PartD
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• v.13D no.1 s.104
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• pp.51-60
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• 2006

Product Line Engineering(PLE) is an effective software development technique which produces applications using core assets. Because of reusing the core assets, PLE can save cost for developing products in a domain but increase reusability. There are about ten PLE methodologies available, but there are not yet common agreements on PLE process and artifacts. This makes developers harder to choose a methodology and to apply it in practice. A comprehensive technical evaluation and comparison on existing PLE methodologies would be essential for practitioners. In this paper, we present a technical assessment of representative PLE methodologies; FAST, SEI SPL, PuLSE, Bosch's PL proceis, FOPLE, ESAPS, KobrA/PoLITe, Alexandria, COPA, QADA. They are compared in the criteria of process, artifacts, instructions, and special features. And we identify common or variable elements between methodologies and confirm elements to be improved in each PLE methodology. The assessment result would be well utilized in defining a practical methodology for PLE projects and in choosing an appropriate methodology among available ones.

• Journal of the Korean Society for Marine Environment & Energy
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• v.18 no.4
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• pp.291-297
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• 2015

The wave spectrum was generated from wave data measured at the Chagwi-do site in Jeju, where a 10MW class floating wave-offshore wind hybrid power generation system will be installed. The latching control technology (Sheng et al.[2015]) was applied in order to improve the extracted power from WEC (Wave Energy Converter), which is heaving in corresponding irregular waves. The peak period as a representative value of irregular waves was used when we determined the latching duration. From the numerical results in the time-domain analysis, the latching control technology can significantly improve the extracted power about 50%.

• Journal of the Korea Computer Industry Society
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• v.2 no.2
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• pp.123-130
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• 2001

As the growth of database volume, it has required a need and an opportunity of data analysis and extracting knowledge from database. Data mining method is the representative example. The size of most minable data set is huge, and stored in a database. To implement effective mining function, we must extract minable data set to be analyzed from existing relational database, and it must be managed with its generalized information. In this paper, the new mining operator is defined in a similar manner to the existing SQL operators and SQL is extended to extract data subset from relations and to generalize it using domain-oriented method. The background knowledge includes attribute values, which will be mind and generalized information, and it is managed as the same structure with a relation in relational database. These functions are implemented by defining some SQL - like operators and aggregated functions, and we describe the expressive powers of these new operators and functions through examples.

• Journal of KIISE:Information Networking
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• v.28 no.4
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• pp.559-569
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• 2001

With the growth of the Internet, applications using the reliable multicast protocol are increasing. Two important requirements of reliable multicasting are reliability and scalability. To enhance scalability, many methods have been proposed. A typical method is a local recovery scheme. This paper proposes a new stable and effective protocol with the following features. The first is to apply the discipline of the separations of concerns to NAK message. By dividing the functions of the NAK message into the error recovery request and the NAK-suppression, each function can be optimized. Second, a local representative, which is selected gradually and distributively, executes error recovery in somewhat deterministic manner. Finally, by dynamically adjusting the TTL value of the control message, the error recovery domain can be optimized. The proposed scheme has been implemented and experimented on Network Simulator. Compared to the existing schemes, the performance results show that scalability has not only been enhanced but also error recovery time and network overhead have been reduced.

• Journal of Korean Society for Atmospheric Environment
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• v.25 no.1
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• pp.15-25
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• 2009

Donghae city is one of the most representative cement industrial city in Korea. The area is faced with the East Sea to the East and with high montane region of Tae-Back mountain range to the West. Many pollutant sources of air pollution are located near the coast, but the largest point sources of the region are located at the bottom of the mountain area in Donghae city. The local wind is highly affected by local topography and plays an important role in transport and dispersion of contaminants from the pollution sources. This study was designed to evaluate enhancement of MM5 predictions by using Four Dimensional Data Assimilation (FDDA), the SONDE data and the national meteorological station, data only. The alternative meteorological fields predicted with and without FDDA were used to simulate spatial and temporal variations of NOx in combined with Atmospheric Dispersion Models (CALPUFF). For the modeling domain, the alternative meteorological fields with 1.1 km spatial resolution were interpolated to the CALMET with 0.5 km resolution. The vertical layers set to have 35 and 12 layers for MM5 and CALPUFF, respectively. MM5 with the FDDA did not resulted in significant improvement of meteorological field prediction in Donghae region, which is primarily because of complex geography and wind scheme. The result of CALPUFF, however, showed reduction of uncertainty errors by using the interpolation scheme of the actual measurement data.

• Journal of Korean Library and Information Science Society
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• v.47 no.4
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• pp.489-510
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• 2016

It is defined in the internal standard of the NAK namely a NAK/G8-1:2013(v.1.) such as TIFF, PNG, PDF/A, JPEG 2000 as a Long-Term Preservation Master File for internal Standardization of Paper Archives in the Central Archives of Korea. This study reviewed the possibility that JPEG format could be a standard as a Long-Term Preservation Master File for internal Standardization of Paper Archives in the Central Archives of Korea. I pointed to the unique characteristics of JPEG file format and analysed and compared with TIFF format that is a representative master file. Through this study, I suggested that JPEG format also should be additionally included in the standard, as a master file, because it meets a qualification and functional requirements of master file and can guarantee the authenticity, reliability, integrity and usability. The meaning of this study is that JPEG format, be added to master file standard, can set up a environment that has lots of benefit in the domain of usability, compatibility to user as well as the authenticity, reliability, integrity.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2018.10a
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• pp.21-21
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• 2018

Natural product substances have historically served as the most significant also be prepared by source of new leads for pharmaceutical development. They can chemical synthesis(both semisynthesis and total synthesis) and have played a important role in the field of organic chemistry by providing synthetic targets. Rcently, they have also been extended for commercial purpose to refer to medicinal products, health functional foods, dietary supplements and cosmetics from natural sources. A large number of currently prescribed drugs have been either directly derived from or inspired by natural products. However, with the advent of robotics, bioinformatics, high throughput screening(HTS), molecular biology-biotechnology, combinatorial chemistry, in silico(molecular modeling) and other methodologies, the pharmaceutical industry has largely moved away from plant derived natural products as a source for leads and prospective drug candidates. The strategy for natural prduct industry is now changing from drug approaches to health foods by identifying effective natural products as preparations. In Korea, a lot of development of natural product based drugs have been done, but very few on health functional foods. The concept of natural product based health foods is not active components as lead compounds but standardized extracts or preparation mixed with other medicinal plants. The representative material has been recently known to be a standardized ginseng extract "Ginsana G 115" developed by Swiss Pharmaton company. The purpose of this presentation is to underline how natural products research continues to make significant contributions in the domain of discovery and development of new health functional foods. It is proposed to present the development of high value added health food or health functional foods through scientific investigation on efficacy and standardization of new materials form natural products.