• The Journal of Korean Physical Therapy
• /
• 제26권6호
• /
• pp.425-429
• /
• 2014

Purpose: The first purpose of this study was to evaluate whether hand muscle fatigue alters sensorimotor control of the hand in healthy subjects, using hand position sense. The second objective was to assess the repositioning variables during a 7.5-min period after the fatigue protocol. Methods: Participants performed a repeated handgrip movement to induce the fatigue condition as fast as possible, until they could no longer continue. Recordings were performed before (pre-fatigue) and after the completion of the fatigue exercises (immediately: post-fatigue, after a 2.5 min recovery, after a 5 min recovery and after a 7.5 min recovery). Results: The joint reposition test of the MP joint in the post-fatigue condition showed higher reposition errors than the prefatigue condition (p<0.05). Additionally, there was a significant difference in recovery of joint reposition errors after fatiguing exercises of the hand muscle, among groups (p<0.05). Conclusion: The fatigue of the hand muscles affected joint position sense by an alteration of somatosensory and proprioceptive information. Nonetheless, the effect of hand muscle fatigue was short-lived, since joint reposition errors decreased to post-fatigue values after 7.5 min of recovery.

• 대한한방내과학회지
• /
• 제37권2호
• /
• pp.243-250
• /
• 2016

Objective: We report a case of a 73-year-old Korean male with vertigo and nausea, both of which were brought about by head repositioning. The condition was diagnosed as benign paroxysmal positional vertigo (BPPV).Method: The patient was treated with acupuncture, electroacupuncture, cupping, transcutaneous electrical nerve stimulation (TENS), and herbal medicine (Bosimsahwacheonggan-tang [補心瀉火淸肝湯]). We conducted the vertigo symptoms scale (VSS) and the dizziness handicap inventory (DHI) to evaluate the degree of the patient’s symptoms.Results: Vertigo and nausea started to improve after the administration of Bosimsahwacheonggan-tang, but although the patient took the anti-vertigo medication and a tranquilizer after the symptoms became aggravated, no prominent improvements could be observed.Conclusion: These results suggest that traditional Korean medical treatment may be effective in treating peripheral vertigo due to BPPV.

• 대한한방내과학회지
• /
• 제37권2호
• /
• pp.273-282
• /
• 2016

Objective: This clinical study was performed with a female patient to evaluate the effects of combined Eastern-Western medicine treatment on benign paroxysmal positional vertigo after acute vestibular neuritis.Method: We used acupuncture, herbal medication, Western medication, fluid therapy, and the canalith repositioning maneuver to treat a female patient suffering from dizzy spells. The vertigo scale was checked to assess any improvement in symptoms.Results: The patient had originally recovered from acute vestibular neuritis, but after the first discharge, she came down with benign paroxysmal positional vertigo and had to be rehospitalized. She eventually got better, however, and her score on the vertigo scale improved.Conclusion: This study demonstrates that combined Eastern-Western medicine treatment may be an effective option for treating benign paroxysmal positional vertigo after acute vestibular neuritis, despite the difficulty of the treatment in this case.

• Restorative Dentistry and Endodontics
• /
• 제37권2호
• /
• pp.110-113
• /
• 2012

본 증례의 편측성 하악 과두 골절 환자는 외상 후 1개월간 다수의 상악 전치부 치아 외상이 간과되어 교합이 붕괴된 상태로 내원하였다. 변위된 상악 전치부 치아들의 외과적 정복 후 지속적인 기능 운동을 진행하여, 10개월 후 정상 교합 및 하악 과두 골절부의 골유합이 확인되는 양호한 결과를 얻을 수 있었다.

• 한국태양에너지학회 논문집
• /
• 제35권3호
• /
• pp.17-25
• /
• 2015

The main objective of this study is to predict the wind power generation at the wind farm using various wake models. Modeling of wind farm is a prerequisite for prediction of annual energy production at the wind farm. In this study, we modeled 20 MW class Seongsan wind farm which has 10 wind turbines located at the eastern part of Jeju Island. WindSim based on the computational fluid dynamics was adopted for the estimation of power generation. The power curve and thrust coefficient with meteorology file were prepared for wind farm modelling. The meteorology file was produced based on the measured data of the Korea Wind Atlas provided by Korea Institute of Energy Research. Three types of wake models such as Jensen, Larsen, and Ishihara et al. wake models were applied to investigate the wake effects. From the result, Jensen and Ishihara wake models show nearly the same value of power generation whereas the Larsen wake model shows the largest value. New positions of wind turbines are proposed to reduce the wake loss, and to increase the annual energy production of the wind farm.

• 대한치과의사협회지
• /
• 제57권2호
• /
• pp.100-104
• /
• 2019

Orthognathic surgery is designed to correct problems of the jaw and face and restore facial harmony. The limitations of orthognathic surgery occur at all steps of the surgical workflow: preoperative planning, simulation, and operation. Many studies have shown the accuracy and advantages of 3 dimensional computer-assisted program for orthognathic surgery. The purpose of this paper is to introduce the accuracy of the maxillary repositioning in patients who underwent orthognathic surgery using a 3 dimensional computer assisted surgery program. The reliability of computer guided orthognathic surgery using splint and surgical guide need to be improved further. The 3 dimensional computer assisted analysis seems to be more precise to interpret than two-dimensional analysis. High-precision planning of orthognathic surgery has predictable results. Three-dimensional computer assisted orthognathic surgery has the following advantages : planned surgical movement is possible, splints guide with CAD/CAM technology; and increase predictable results .Computer assisted simulation surgery ensures accuracy during surgery, thereby facilitating predictable results. It may provide solution that enables surgeon to perform planned surgery more accurately.

• 대한심미치과학회지
• /
• 제29권1호
• /
• pp.13-24
• /
• 2020

임플란트 술식은 그 동안 많은 발전을 하였고, 자연치를 대체할 훌륭한 치료법임에는 부인할 수 없지만 치주인대가 존재하지 않는 구조적 한계점, 발치 직후 시작되는 bundle bone의 흡수는 자연치와 같은 적절한 emergence profile을 만들어내기 어려울 수 있고 이는 심미적인 결과로 이어질 수 있다. 만약 해당 환자의 구강 내에 건전한 제3대구치가 있고, 결손부위의 염증상태가 심각하지 않으면 건전한 제3대구치를 결손된 부위로 이식하여 치아를 재건할 수 있다. 성공적인 자가치아이이식술은 저작기능을 회복하고, 자가치아를 이용하기에 생체 친화적이며, 치조골의 흡수를 예방하는 훌륭한 치료이기 때문에 가능하기만 하다면 첫번째 치료로 충분히 고려될 수 있을 것이다.

• Biomolecules & Therapeutics
• /
• 제29권5호
• /
• pp.519-526
• /
• 2021

In a search for effective PPAR-γ agonists, 110 clinical drugs were screened via molecular docking, and 9 drugs, including parecoxib, were selected for subsequent biological evaluation. Molecular docking of parecoxib to the ligand-binding domain of PPAR-γ showed high binding affinity and relevant binding conformation compared with the PPAR-γ ligand/antidiabetic drug rosiglitazone. Per the docking result, parecoxib showed the best PPAR-γ transactivation in Ac2F rat liver cells. Further docking simulation and a luciferase assay suggested parecoxib would be a selective (and partial) PPAR-γ agonist. PPAR-γ activation by parecoxib induced adipocyte differentiation in 3T3-L1 murine preadipocytes. Parecoxib promoted adipogenesis in a dose-dependent manner and enhanced the expression of adipogenesis transcription factors PPAR-γ, C/EBPα, and C/EBPβ. These data indicated that parecoxib might be utilized as a partial PPAR-γ agonist for drug repositioning study.

• Physical Therapy Rehabilitation Science
• /
• 제10권1호
• /
• pp.69-75
• /
• 2021

Objective: This study was aimed at investigating the effects of lumbar stabilization exercise according to correct verbal instructions in pain and muscle strengthening of the low back pain patients. Design: A randomized controlled trial. Methods: Twenty subjects with low back pain were selected. They were randomly assigned to one of two groups (10 in each group): namely the lumbar stabilization exercise and lumbar stabilization exercise according to the correct verbal instructions group. The lumbar stabilization exercise group performed lumbar stabilization exercises for 6 weeks (5 times a week). The lumbar stabilization exercise according to correct verbal instructions group performed lumbar stabilization exercise according to correct verbal instructions for 6 weeks (5 times a week). We measured pain, muscle power, proprioception, and body balance before and after exercise by using visual analog scale (VAS), digital handheld dynanometer, Joint repositioning error, time up and go test respectively. Results: We found statistically significant differences in pain, muscle power, proprioception, and body balance in lumbar stabilization exercise and lumbar stabilization exercise according to correct verbal instructions group, before and after (p<0.05). Conclusions: We confirmed the effect of lumbar stabilization exercise according to correct verbal instructions. Thus we thought these results could be used as basic data and reference for low back pain. But we need more study effect of correct verbal instructions on other exercises.

• Journal of Veterinary Science
• /
• 제23권4호
• /
• pp.58.1-58.10
• /
• 2022

Background: Laryngeal paralysis is a common idiopathic degenerative neurological disease in older medium-to-large breed dogs, with surgical correction of the obstruction being the treatment of choice. Objectives: This study evaluated the use of laryngeal silicone stents to treat canine laryngeal paralysis in dogs where classic surgical treatment was not accepted by the owners. Methods: Dogs diagnosed with laryngeal paralysis, for which the owners refused arytenoid lateralization surgery as a first-line treatment, were treated with laryngeal silicone stents. Results: Six dogs with bilateral laryngeal paralysis were included in the study. All dogs showed improvement in clinical signs immediately after the procedure. No clinical signs or radiographic changes were noted in four out of six dogs in the follow-up visit performed 1 wk later. One dog was suspected of aspirating water while drinking, but the signs disappeared after repositioning the stent. Another dog had a relapse of stridor due to caudal migration of the stent. This dog underwent arytenoid lateralization surgery because larger stents are not commercially available. At the time of writing, between seven and 13 mon after stent placement, no significant incidents have occurred in four dogs, and all owners report a satisfactory quality of life. Conclusions: Laryngeal silicone stenting is an interesting alternative for treating dogs with acquired laryngeal paralysis when the owners refuse classic arytenoid lateralization surgery. Furthermore, stent placement can be a temporary solution to stabilize these dogs until a permanent surgical treatment can be performed.