• 제목/요약/키워드: replace period

검색결과 215건 처리시간 0.021초

Effects of Pretense Inhibitors and Antioxidants on In Vitro Survival of Porcine Primordial Germ Cells

  • Lee, Chang-Kyu;Jorge A. Piedrahita
    • 한국발생생물학회:학술대회논문집
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    • 한국발생생물학회 2001년도 발생공학 국제심포지움 및 학술대회 발표자료집
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    • pp.47.1-47
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    • 2001
  • One of the problems associated with in vitro culture of primordial gern cells (PGCs) is the large loss of cells during the initial period of culture. This study characterized the initial loss and determined the effectiveness of two classes of apoptosis inhibitors, protease inhibitors and antioxidants, on the ability of the porcine PGCs to survive in culture. Results from electron microscopic analysis and in situ DNA fragmentation assay indicated that porcine PGCs rapidly undergo apoptosis when placed in culture. Additionally, \ulcorner2-macroglobulin, a protease inhibitor and cytokine carrier, and N-acetylcysteine, an antioxidant, increased the survival of PGCs in vitro. While other protease inhibitors tested did not affect survival of PGCs, all antioxidants tested improved survival of PGCs (p<0.05). Further results indicated that the beneficial effect of the antioxidants was critical only during the initial period of culture. Finally, it was determined that in short-term culture, in the absence of feeder layer, antioxidants could partially replace the effect(s) of growth factors and reduce apoptosis. Collectively, these results indicate that the addition of \ulcorner2-macroglobulin and antioxidatns can increase the number of PGCs in vitro by suppressing apoptosis.

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플라즈마를 이용한 FGR 기반 저 NOx 연소 타당성 연구 (Feasibility Study of Low NOx Combustion based on FGR using Plasma Reformer)

  • 김관태;이대훈;차민석;길상인;윤진한;김동현;송영훈
    • 한국연소학회지
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    • 제12권3호
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    • pp.1-7
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    • 2007
  • A combined hydrogen generator of plasma and catalytic reformer was developed, and was applied to stabilize unstable flame of 200,000 Kcal/hr LPG combustor. The role of the plasma reformer was to generate hydrogen in a short period and to heat-up the catalytic reformer during the start-up time. After the start-up period, the catalytic reformer generates hydrogen through steam reforming with oxygen (SRO) reactions. The maximum capacity of the hydrogen generator was enough 100 lpm to stabilize the flame of the present combustor. In order to reduce NOx and CO emissions simultaneously, 1) FGR (Flue Gas Recirculation) technique has been adopted and 2) the hydrogen was added into the fuel supplied to the combustor. Test results showed that the addition of 25% hydrogen and 30% FGR rate lead to simultaneous decrease of CO and NOx emissions. The technique developed in the present study showed good potential to replace $NH_3$ SCR technique, especially in the small-scale combustor applications.

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고고도 장기체공 무인기 동체 및 미익부 구조해석 (Structural Analysis of Fuselage and Empennage of High Altitude Long Endurance UAV)

  • 김현기;김성준;김성찬;신정우;이승규;박상욱;김태욱
    • 한국항공운항학회지
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    • 제24권4호
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    • pp.35-43
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    • 2016
  • UAV has been promoted for practical use in the field of civilian and military. Recently, UAV is required high-specification performance such as long-term flight and precision observation. Among these UAVs, High Altitude Long Endurance UAV(HALE UAV) has been developed for the purpose to replace some of the functions of the satellite such as meteorological observation, communications and internet relay while flying a long period in the stratosphere. In order to fly a long period in harsh environment of the stratosphere, aircraft needs high Lift-Drag-Ratio and weight reduction of the structure. This paper performed the structural analysis for fuselage and empennage of HALE UAV. Critical loading conditions for structural analysis are acquired from flight load analysis and finally the results of structural sizing for weight reduction is presented.

저 NOx 연소를 위한 플라즈마 개질기 (Plasma Reformer for Low NOx Combustion)

  • 김관태;이대훈;차민석;길상인;윤진한;송영훈
    • 한국연소학회:학술대회논문집
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    • 한국연소학회 2007년도 제34회 KOSCO SYMPOSIUM 논문집
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    • pp.187-190
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    • 2007
  • A combined hydrogen generator of plasma and catalytic reformers has been developed, and has been applied to stabilize unstable flame of 200,000 Kcal/hr LPG combustor. The role of the plasma reformer is to generate hydrogen in a short period and to heat-up the catalytic reformer during the start-up time. After the start-up period, the catalytic reformer generates hydrogen through steam reforming with oxygen (SRO) reactions. The maximum capacity of the hydrogen generator is 100 lpm that is sufficient to be used to stabilize the flame of the present combustor. In order to reduce NOx and CO emissions simultaneously, 1) FGR (Flue Gas Recirculation) technique has been adopted and 2) the hydrogen has been added into the fuel supplied to the combustor. Test results shows that 25 % addition of hydrogen and 30 % FGR rate lead to simultaneous decrease of CO and NOx emissions. The technique proposed in the present study shows good potential to replace $NH_3$ SCR technique, especially in the case of small-scale combustor applications.

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An Opportunity-based Age Replacement Policy with Warranty Analysed by Using TTT-Transforms

  • Iskandar, Bermawi P.;Klefsjo, Bengt;Sandoh, Hiroaki
    • International Journal of Reliability and Applications
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    • 제1권1호
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    • pp.27-38
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    • 2000
  • In a recent paper Iskandar & Sandoh (1999) studied an opportunity-based age replacement policy for a system which has a warranty period (0,S]. When the system fails at age x $\leq$ S a minimal repair is performed. If an opportunity occurs to the system at age x, S $\leq$ x $\leq$ T, we take the opportunity with probability p to preventively replace the system, while we conduct a corrective .replacement when its fails in (S,T). Finally, if its age reaches T, we perform a preventive replacement, Under this policy the design variable is T. For the case when opportunities occur according to a homogeneous Poisson process, the long-run average cost of this policy was formulated and studied analytically by Iskandar & Sandoh (1999). The same problem is here analysed by using a graphical technique based on scaled TTT-transforms. This technique gives, among other things, excellent possibilities for different types of sensitivity analysis. We also extend the discussion to the situation when we have to estimate T based on times to failure.

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인공부식재의 피로강도평가와 통계학적 수명예측에 관한 연구 (Life Prediction and Fatigue Strength Evaluation for Surface Corrosion Materials)

  • 권재도;진영준;장순식
    • 대한기계학회논문집
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    • 제16권8호
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    • pp.1503-1512
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    • 1992
  • 본 연구에서는 열화평가 및 수명예측에 있어서 가장 중요한 문제로 대두되는 기계구조물의 사용시간과 부식 정도에 대한 관계 곡선을 규명하기 위하여 실험실의 가혹 환경하에서 부식을 시키면서 표면을 측정한 데이터로 통계적인 파라메타(parame- ter)를 추정하여, 인공부식시킨 부식재로 피로 강도를 평가하고, 또 부식된 구조물의 잔존수명을 예측할 수 있는 하나의 방법을 제시하고저 한다.

Effects of Protease Inhibitors and Antioxidants on In Vitro Survival of Porcine Primordial Germ Cells

  • Lee, Chang-Kyu;Jorge A. Piedrahita
    • 한국동물번식학회:학술대회논문집
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    • 한국동물번식학회 2001년도 발생공학 국제심포지움 및 학술대회 발표자료집
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    • pp.47-47
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    • 2001
  • One of the problems associated with in vitro culture of primordial germ cells (PGCs) is the large loss of cells during the initial period of culture. This study characterized the initial loss and determined the effectiveness of two classes of apoptosis inhibitors, protease inhibitors and antioxidants, on the ability of porcine PGCs to survive in culture. Results from electron microscopic analysis and in situ DNA fragmentation assay indicated that porcine PGCs rapidly undergo apoptosis when placed in culture. Additionally,? 2-macroglobulin, a protease inhibitor and cytokine carrier, and N-acetylcysteine, an antioxidant, increased the survival of PGCs in vitro. While other protease inhibitors tested did not affect survival of PGCs, all antioxidants tested improved survival of PGCs (p〈0.05). Further results indicated that the beneficial effect of the antioxidants was critical only during the initial period of culture. Finally, it was determined that in short-term culture, in the absence of feeder layers, antioxidants could partially replace the effect(s) of growth factors and reduce apoptosis. Collectively, these results indicate that the addition of ?2-macroglobulin and antioxidants can increase the number of PGCs in vitro by suppressing apoptosis.

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MSR_FSB_FREQ 제어를 이용한 윈도우 운영체제에 실시간 처리 방법 (Real-time Processing Method for Windows OS Using MSR_FSB_FREQ Control)

  • 김종진;이상길;이철훈
    • 한국멀티미디어학회논문지
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    • 제24권1호
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    • pp.95-105
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    • 2021
  • In the case of laptops and tablet PC's that replace desktop, it uses the Windows operating system to provide various functions depending on operating system dependency, the Windows operating system does not support real-time processing because it uses multi-level feedback queue scheduling that extends round-robin scheduling. Also, since the initial value of Local APIC Counter can not be obtained from the Windows 8, the real-time processing function provided through the existing RTiK does not work. In this paper, we calculate Local APIC Counter value by using MSR_FSB_FREQ register to support real-time processing function on tablet PC's. We designed and implemented RTiK+, which provides real-time processing function to guarantee the periodicity by calculating the operation time of accurate timer. In order to verify and evaluate the performance of the implemented the RTiK+, the period was measured by using the Read Time-Stamp Counter(RDTSC) instruction and it was confirmed that it operates normally at 1ms and 0.1ms period.

Effects of Fermented Rapeseed Meal on Growth Performance and Serum Parameters in Ducks

  • Fazhi, Xu;Lvmu, Li;Jiaping, Xu;Kun, Qian;Zhide, Zhang;Zhangyi, Liang
    • Asian-Australasian Journal of Animal Sciences
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    • 제24권5호
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    • pp.678-684
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    • 2011
  • A trial was performed to study the effects of feeding a diet containing solid-state fermentation rapeseed meal (FRSM) replaced soybean meal (SBM) on growth performance and serum biochemistry parameters of ducks and then to determine the appropriate proportion of soybean meal replacement. The 75% rapeseed meal and 25% blood meal were mixed and inoculated with the Lactobacillus plantarum and Bacillus subtilis. Over the 21-day fermentation, isothiocyanates were reduced from 72.7 to 14.1 mmol/kg. A total of 1,280 fifteen-day-old Cherry Valley ducks were randomly allocated into 4 dietary treatments, 4 replicate groups of 80 ducks each for a 30-day feeding trial. In four treatment groups, fermentation rapeseed meal replaced soybean meal at 0, 33, 67 or 100%, respectively. Results showed that feed intake of ducks fed 100% FRSM was greater (p<0.05) than SBM and partial FRSM in both the finishing period (31-45 d) and entire feeding period (15-45 d). Daily gain increased gradually in the three treatment groups with augmenting FRSM over in the whole study period. In the growing period (15-30 d), compared with the SBM group, phosphorus and calcium content in serum from the FRSM group was improved (p<0.05). Total protein concentration was lower in ducks fed 100% FRSM than SBM and 33% FRSM (p<0.05). Concentrations of IgM were dramatically higher for animals fed 100% FRSM than in the SBM, 33% FRSM and 67% FRSM groups. In the finishing trail stage (31-45 d), only serum IgG content in 100% FRSM group was improved (p<0.05). Therefore, rapeseed meal fermented with Lactobacillus plantarum and Bacillus subtilis is a promising alternative protein source and fermented rapeseed meal can completely replace soybean meal in duck diet and potentially reduce the cost of duck production.

Evaluation of Bio-V-Pro® as an Alternative Protein Source in Broiler Diets

  • Han, In K.;Kim, J.H.;Piao, X.S.;Bae, S.H.;Han, Y.K.
    • Asian-Australasian Journal of Animal Sciences
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    • 제11권1호
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    • pp.71-77
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    • 1998
  • The experiment was conducted to evaluate Bio-V-Pro as an alternative protein source in broiler diets. Treatments were control, Bio-V-Pro 1% (BP 1), Bio-V-Pro 3% (BP 3), and Bio-V-Pro 5% (BP 5). During the starter period, all treated groups showed beter performance than control group in weight gain and feed intake (p < 0.05). The best FCR was observed in BP 1 group and the worst was found in BP 5 group. For the overall period, chicks fed BP 1 and BP 3 diets gained more than the chicks fed the control and BP 5 diets. All Bio-V-Pro fed groups consumed more feed than the control group (p < 0.05). FCR were similar between the control and BP 1 group, but BP 3 and BP 5 groups showed higher FCR than the control group. During the starter period, all BP groups showed better utilizability of crude protein, crude ash and phosphorus than the control group (p < 0.05). For the finisher period, except for the BP 5 group, the nutrient utilizability was not significantly different in most nutrients. Nutrients utilizability had a tendency (not significant) to decrease as the level of Bio-V-Pro in the diet was increased. Lysine utilizability was not affected by the dietary treatment, however, methionine utilizability was higher in BP 1 and BP 3 group than in the control group. From the results of this experiment, it seems that Bio-V-Pro is a good alternative protein source which can replace fish meal in starter diet up to 3% of the diet effectively.