• 제목/요약/키워드: repeated exposure

검색결과 249건 처리시간 0.03초

노트북 거치대가 건강한 젊은 성인 손목관절근육의 생체역학적 특징에 미치는 영향 (Effects of a Notebook Computer Supporter on Biomechanical Characteristics in Wrist Joint Muscles of Healthy Young Adults)

  • 마성룡;송창순
    • PNF and Movement
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    • 제19권3호
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    • pp.391-399
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    • 2021
  • Purpose: As laptop use increases throughout the COVID-19 pandemic and its use outside of traditional workstations proliferates, it is imperative to expand the limited research available regarding ergonomic exposure. This study aimed to identify the effects of a laptop supporter on biomechanical characteristics in the wrist joint muscles of healthy young adults. Methods: This was a cross-sectional observational study design with thirty-four healthy young adults as participants. They conducted a typing exercise performed under two different conditions, which were with and without a notebook computer supporter. This study measured the biomechanical characteristics of the muscles of the wrist joints including the flexor carpi ulnaris (FCU), the flexor carpi radialis (FCR), the extensor carpi radialis longus (ECRL), and the extensor carpi ulnaris (ECU). Measurements were taken three times: before typing, immediately after typing for 30 minutes with a supporter, and immediately after typing for 30 minutes without a supporter. The statistical method to compare the three different measurement conditions was the repeated measures ANOVA. Results: The participants showed significantly different levels of dynamic stiffness in both the FCU before typing and immediately after 30 minutes of typing with a supporter, and showed significantly different levels of dynamic stiffness in the FCR before typing and immediately after 30 minutes of typing with a supporter. The dynamic stiffness level immediately after 30 minutes of typing without a supporter was significantly different than that immediately after 30 minutes of typing with a supporter. However, the muscle tone was not significantly different among the three different conditions. Conclusion: The results of this study revealed that a laptop supporter used to correct the eye level of the electronic screen increases the dynamic stiffness of the wrist joint flexors, so it is necessary to consider the neutral position of the wrist joint during typing.

치면열구전색 전후의 어린이 소변 내 Bisphenol-A의 농도 변화 (Changes in bisphenol A concentrations in urine according to sealant filling in children)

  • 신아라;김지혜;전은숙;정윤숙;송근배;최연희
    • Journal of Korean Academy of Oral Health
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    • 제41권4호
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    • pp.231-236
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    • 2017
  • Objectives: The objectives of this study were to investigate the changes in bisphenol A (BPA) concentrations in urine from before to after sealant filling and the relationship between BPA and the number of teeth with sealed surfaces. Methods: Thirty-one children aged 6 and 7 years from three elementary schools in Daegu city who did not have any sealant and resin filling were selected as subjects. Urine samples were collected before and after sealant filling until 24 hours, with informed consent from their caregivers. The BPA concentration in all the collected urine samples was analyzed at Seegene Medical. Statistical analysis was performed using the Friedman test, Scheirer-Ray-Hope test, and the repeated-measures generalized linear mixed model of SPSS version 22.0. Results: The BPA concentrations increased from $3.49-{\mu}g/g$ creatinine before to $4.91-{\mu}g/g$ creatinine 2-3 hours later and to $4.15-{\mu}g/g$ creatinine after 24 hours. The more teeth with sealed surfaces, the higher the BPA concentration in children, but the difference was not statistically significant (P>0.05). Conclusions: The BPA concentrations were highest at 2-3 hours after sealant filling and decreased at 24 hours. Exposure to the sealant appears to have a meaningful correlation with the concentration of BPA in the urine of children.

실내·외 보행환경의 변화가 40대와 노인의 보행속도와 다리 근활성도에 미치는 영향 (Effects of Changes in the Indoor and Outdoor Environmental on the Walking Speed and Lower Extremity Muscle Activities in People Aged Forty and Older than Seventy Years)

  • 이준영;김택훈
    • 대한물리의학회지
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    • 제13권4호
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    • pp.139-148
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    • 2018
  • PURPOSE: This study compared the effects of indoor and outdoor environmental changes on the activity of the major lower limb muscles and walking factors in people 40-50 years and those aged older than 70 years. METHODS: Ten middle-aged people in their forties (age:$44.2{\pm}2.7$, BMI:$21.8{\pm}1.8$) and 10 elderly aged more than 70 years (age:$76.4{\pm}5.9$, BMI:$22.2{\pm}1.9$) with a normal walking ability were included. The participants walked 100 m both indoors and outdoors at their own speed. Using a 3D motion analyzer and EMG, the walking speed, angle of the ankle and activity changes of the lower limb muscles were compared. RESULTS: Significant differences in walking speed and peak-plantar flexion angle were observed between the two groups (p<.05). The muscular activity of the gastrocnemius muscle (GCM) was significantly different outdoors in the swing phase between the two groups (p<.05). In the people aged in their forties, the muscular activity of the rectus femoris (RF) was significantly higher outdoors than indoors (p<.05). In the elderly, however, the muscular activity of the RF was lower outdoors than indoors (p<.05). When compared to those in there forties, the muscular activity of the outdoor RF significantly decreased in the elderly group (P<.05). The muscular activity of the biceps femoris (BF) in the elderly decreased significantly outdoors compared to indoors (p<.05). CONCLUSION: For the elderly, increasing the exposure to the new environments or focusing on the performance of repeated movements for gradual speed control and precise movements is required to maintain normal gaits and movements that are less affected by environmental changes.

치과방사선사진과 증강현실을 활용한 방사선촬영법 숙련용 디지털 콘텐츠 개발에 대한 융복합 연구 (Convergence and integration study related to development of digital contents for radiography training using dental radiograph and augmented reality)

  • 구자영;이재기
    • 디지털융복합연구
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    • 제16권12호
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    • pp.441-447
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    • 2018
  • 이 연구의 목적은 증강현실기술을 활용하여 치과 방사선 촬영술의 반복 연습이 가능한 디지털 콘텐츠를 개발하는데 있다. 성인 모델의 외형을 사진 촬영하고, 실습용 마네킹 팬텀을 컴퓨터 단층 촬영한 후, 이를 중첩하여 삼차원 객체를 제작하였다. 또한, 결과로 출력되는 106장의 방사선사진은 촬영법과 관련된 치아 정보를 활용하여 데이터베이스화하였고, 학습자가 성공적인 촬영을 수행하면 각 촬영조건에 맞는 부위별 영상이 호출되도록 시스템을 구축하였다. 이를 통해 임상 전 단계에서의 연습을 반복적으로 시행할 수 있었다. 이 콘텐츠를 이용하여 치과위생사의 방사선 촬영 임상 실무역량을 향상하는데 기여하고자 한다. 다만, 직접 얼굴인식을 통해 촬영하는 것이 실습효용 가치가 클 것으로 예상하기 때문에 이에 관련한 후속 연구가 필요하다.

The Evaluation of the Acute Toxicity and Safety of Verbenalin in ICR Mice

  • Hyejeong, Shin;Yigun, Lim;Jisu, Ha;Gabsik, Yang;Taehan, Yook
    • Journal of Acupuncture Research
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    • 제39권4호
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    • pp.310-316
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    • 2022
  • Background: Verbenalin is an iridoid glucoside, which is among the active components of some medicinal herbs such as Verbena officinalis Linn, and Cornus officinalis Siebold and Zucc. Previous studies have confirmed the antioxidant activity and neuroprotective potential of verbenalin. To confirm the safety of verbenalin, an approximate lethal dose was determined based on a single oral dose toxicity study. Methods: Institute of Cancer Research mice were randomly assigned to three verbenalin exposure groups (250, 500, and 1,000 mg/kg) and a control group (5% methylcellulose solution). There were (5 male and 5 female mice per group). Mortality, clinical signs, and body weight were monitored for 14 days, and necropsies were conducted. Results: No mortalities were observed in the control group or the verbenalin 250 mg/kg group, whereas mortalities were observed in the 500 mg/kg and 1,000 mg/kg verbenalin groups. During the observation period, stool abnormalities such as mucous stools were observed. Clinical signs such as loss of locomotor activity were observed in the 500 mg/kg and 1,000 mg/kg verbenalin groups. During the study period, significant changes in body weight were observed in the 500 mg/kg and 1,000 mg/kg verbenalin groups; however, no gross abnormalities were observed at necropsy. Overall, no toxicity was found in the 250 mg/kg group. Conclusion: The approximate lethal dose of verbenalin was estimated to be 500 mg/kg. For a more accurate assessment of the safety of verbenalin, other types of studies such as repeated-dose toxicity studies should also be conducted.

Bulb of Lilium longiflorum Thunb Extract Fermented with Lactobacillus acidophilus Reduces Inflammation in a Chronic Obstructive Pulmonary Disease Model

  • Ji-Eun Eom;Gun-Dong Kim;Young In Kim;Kyung min Lim;Ju Hye Song;Yiseul Kim;Hyeon-Ji Song;Dong-Uk Shin;Eun Yeong Lim;Ha-Jung Kim;Sung Hoon Kim;Deuk Sik Lee;So-Young Lee;Hee Soon Shin
    • Journal of Microbiology and Biotechnology
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    • 제33권5호
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    • pp.634-643
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    • 2023
  • Chronic obstructive pulmonary disease (COPD), one of the leading causes of death worldwide, is caused by repeated exposure to harmful matter, such as cigarette smoke. Although Lilium longiflorum Thunb (LLT) has anti-inflammatory effects, there is no report on the fermented LLT bulb extract regulating lung inflammation in COPD. Thus, we investigated the protective effect of LLT bulb extract fermented with Lactobacillus acidophilus 803 in COPD mouse models induced by cigarette smoke extract (CSE) and porcine pancreas elastase (PPE). Oral administration of the fermented product (LS803) suppressed the production of inflammatory mediators and the infiltration of immune cells involving neutrophils and macrophages, resulting in protective effects against lung damage. In addition, LS803 inhibited CSE- and LPS-induced IL-6 and IL-8 production in airway epithelial H292 cells as well as suppressed PMA-induced formation of neutrophil extracellular traps in HL-60 cells. In particular, LS803 significantly repressed the elevated IL-6 and MIP-2 production after CSE and LPS stimulation by suppressing the activity of the nuclear factor kappa-light-chain-enhancer of activated B (NFκB) in mouse peritoneal macrophages. Therefore, our results suggest that the fermented product LS803 is effective in preventing and alleviating lung inflammation.

Prediction of tensile strength degradation of corroded steel based on in-situ pitting evolution

  • Yun Zhao;Qi Guo;Zizhong Zhao;Xian Wu;Ying Xing
    • Steel and Composite Structures
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    • 제46권3호
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    • pp.385-401
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    • 2023
  • Steel is becoming increasingly popular due to its high strength, excellent ductility, great assembly performance, and recyclability. In reality, steel structures serving for a long time in atmospheric, industrial, and marine environments inevitably suffer from corrosion, which significantly decreases the durability and the service life with the exposure time. For the mechanical properties of corroded steel, experimental studies are mainly conducted. The existing numerical analyses only evaluate the mechanical properties based on corroded morphology at the isolated time-in-point, ignoring that this morphology varies continuously with corrosion time. To solve this problem, the relationships between pit depth expectation, standard deviation, and corrosion time are initially constructed based on a large amount of wet-dry cyclic accelerated test data. Successively, based on that, an in-situ pitting evolution method for evaluating the residual tensile strength of corroded steel is proposed. To verify the method, 20 repeated simulations of mass loss rates and mechanical properties are adopted against the test results. Then, numerical analyses are conducted on 135 models of corrosion pits with different aspect ratios and uneven corrosion degree on two corroded surfaces. Results show that the power function with exponents of 1.483 and 1.091 can well describe the increase in pit depth expectation and standard deviation with corrosion time, respectively. The effect of the commonly used pit aspect ratios of 0.10-0.25 on yield strength and ultimate strength is negligible. Besides, pit number ratio α equating to 0.6 is the critical value for the strength degradation. When α is less than 0.6, the pit number increases with α, accelerating the degradation of strength. Otherwise, the strength degradation is weakened. In addition, a power function model is adopted to characterize the degradation of yield strength and ultimate strength with corrosion time, which is revised by initial steel plate thickness.

흉부 CT 스캔에서 재구성 알고리즘 변화적용 시 화질과 스캔 선량 분석 (Analysis of Image Quality and Scan Dose when Applying Reconstruction Algorithm Changes to Chest CT Scans)

  • 김현주
    • 한국방사선학회논문지
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    • 제17권6호
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    • pp.819-825
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    • 2023
  • 흉부 CT 검사 조건 중 관전압을 100, 80 kVp, 재구성 알고리즘을 FBP, ASIR-V, DLIR로 변화 적용하여 검사 선량과 화질 변화를 비교 분석해 보았다. 그 결과 기존 관전압 보다 낮은 관전압인 100 kVp 에서 ASIR-V, DLIR 적용 시 선량을 낮추면서 120 kVp, FBP 적용 시와 가장 유사한 화질로 구현. 특히, DLIR 재구성 영상은 모든 관전압에서 SNR, CNR이 우수하였다. 또한, SSIM 지수가 1에 가장 근사하게 분석되어 원본 영상과 가장 유사도가 높은 것을 알 수 있었다. 따라서 반복적으로 흉부 CT 검사를 시행하는 경우 DLIR 적용은 검사 선량을 약 29.7% 감소시킬 수 있어 CT 검사의 가장 큰 문제점인 검사로 인한 피폭을 일부 해결하는 데 도움을 줄 수 있을 것으로 사료된다.

교사 내 플랜트 모델 유형별 적용에 따른 공기질 변화 (Changes in Air Quality through the Application of Three Types of Green-Wall Model within Classrooms)

  • 양호형;김형주;방성원;조흔우;이형석;한승원;김광진;김호현
    • 한국환경보건학회지
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    • 제49권6호
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    • pp.295-304
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    • 2023
  • Background: Adolescents are relatively more sensitive than adults to exposure to indoor pollutants. The indoor air quality in classrooms where students spend time together must therefore be managed at a safe level because it can affect the health of students. Objectives: In this study, three types of green-wall models were applied to classrooms where students spend a long time in a limited space, and the resulting effects on reducing PM were evaluated. Methods: In the middle school classrooms which were selected as the experimental subjects, IoT-based indoor air quality monitoring equipment was installed for real-time monitoring. Three types of plant models (passive, active, and active+light) were installed in each classroom to evaluate the effects on improving indoor air quality. Results: The concentration of PM in the classroom is influenced by outdoor air quality, but repeated increases and decreases in concentration were observed due to the influence of students' activities. There was a PM reduction effect by applying the green-wall model. There was a difference in PM reduction efficiency depending on the type of green-wall model, and the reduction efficiency of the active model was higher than the passive model. Conclusions: The active green-wall model can be used as an efficient method of improving indoor air quality. Additionally, more research is needed to increase the efficiency of improving indoor air quality by setting conditions that can stimulate the growth of each type of plant.

Effect of three common hot beverages on the force decay of orthodontic elastomeric chain within a 28-day period: An in vitro study

  • Maziar Nobahari;Fatemeh Safari;Allahyar Geramy;Tabassom Hooshmand;Mohammad Javad Kharazifard;Sepideh Arab
    • 대한치과교정학회지
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    • 제54권3호
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    • pp.153-159
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    • 2024
  • Objective: This study aimed to assess the effects of commonly consumed hot drinks on the force decay of orthodontic elastomeric chains. Methods: This in vitro experimental study evaluated 375 pieces of elastomeric chains with six rings placed on a jig. Four rings were stretched by 23.5 mm corresponding to the approximate distance between the canine and the second premolar. Fifteen pieces served as reference samples at time zero, and 360 pieces were randomized into four groups: control, hot water, hot tea, and hot coffee. Each group was further divided into six subgroups (n = 15) according to the different exposure periods. The specimens in the experimental groups were exposed to the respective solutions at 65.5℃ four times per day for 90 seconds at 5-second intervals. The control group was exposed to artificial saliva at 37℃. The force decay of the samples was measured at 1, 2, 7, 14, 21, and 28 days using a universal testing machine. Data were analyzed using repeated-measures analysis of variance. Results: Maximum force decay occurred on day 1 in all groups. The minimum force was recorded in the control group, followed by the tea, coffee, and hot water groups on day 1. At the other time points, the minimum force was observed in the tea group, followed by the control, coffee, and hot water groups. Conclusions: Patients can consume hot drinks without concern about any adverse effect on force decay of the orthodontic elastomeric chains.