• Bulletin of the Korean Chemical Society
• /
• v.28 no.2
• /
• pp.257-262
• /
• 2007

The efficient synthesis of a tetrasaccharide, the suitably protected form of the repeat unit, →2)-α-D-Manp-(1→2)-β-D-Manp-(1→3)-α-D-GlcpNAc-(1→6)-α-D-Manp-(1→, of the O-antigen polysaccharide of the lipopolysaccharide from E. coli O77 has been accomplished. Glycosylation reactions for the coupling of four monosaccharide building blocks of the tetrasaccharide were carried out employing the CB glycoside method, the mannosyl 4-pentenoate/PhSeOTf method, and the glycosyl trichloroacetimidate method with complete stereoselectivities in excellent yields.

• ETRI Journal
• /
• v.26 no.5
• /
• pp.405-412
• /
• 2004

MC-CDMA, a multicarrier (MC) modulation scheme based on code division multiple access (CDMA), is the most likely candidate for the next generation of mobile radio communications. The rate compatible punctured turbo (RCPT) coded hybrid automatic repeat request (HARQ) has been found to give improved throughput performance in a direct sequence (DS) CDMA system. However, the extent to which the RCPT HARQ improves the throughput performance of an MC-CDMA system has not been fully understood. In this paper, we apply the RCPT HARQ to MC-CDMA and evaluate by computer simulations its performance in a frequency selective Rayleigh fading channel. We found that the performance of RCPT HARQ MC-CDMA is almost insensitive to channel characteristics. The performance can be drastically improved with receive diversity combined with space-time transmit diversity. In addition, the comparison of RCPT HARQ MC-CDMA, orthogonal frequency division multiplexing, and DS-CDMA shows that under similar conditions the throughput of MC-CDMA is the best in a frequency selective fading channel.

• Biomedical Science Letters
• /
• v.26 no.1
• /
• pp.47-50
• /
• 2020

Recently, decades of robust researches on degenerative brain disorder have been highlighted on the interactive connection of gut and brain. In terms of inflammatory cytokine production, others have shown that Nucleotide-Binding Oligomerization Domain Containing 2 (NOD2) is involved with Leucine-Rich Repeat Kinase 2 (LRRK2). HEK293T cells were transiently co-transfected with Myc-tagged LRRK2 and Flag-tagged NOD2 and then followed by co-immunoprecipitation assay. In this study, we provide the novel finding of physical protein-protein interaction between NOD2 and LRRK2. G2019S variant has shown stronger interactions against NOD2 than those of wild type LRRK2. In an axis of NOD2-LRRK2 communication, it is believed to pave a new way in the understanding of the bidirectional molecular mechanism of brain disorder, including Parkinson's disease into gut inflammatory disease, including Crohn's disease.

• The Journal of the Acoustical Society of Korea
• /
• v.30 no.2
• /
• pp.86-91
• /
• 2011

In the underwater communications, the acoustic channel is in poor communication conditions, such as long propagation delay, narrow bandwidth, and high bit-error rate. For these bad acoustic channels, we propose an efficient automatic repeat request (ARQ) for multi-hop underwater network by using the concepts of concurrent bi-directional transmission, multiple sub-packets, and overhearing data packet instead of the acknowledgement signal. Our results show that the proposed ARQ significantly reduces the transmission latency especially in high BER compared with the existing Stop and Wait ARQ.

• Journal of Communications and Networks
• /
• v.14 no.5
• /
• pp.510-517
• /
• 2012

This paper analyzes the performance of voice-over-Internet protocol (VoIP) services in terms of the system throughput, the packet delay, and the signaling overhead in a mobile WiMAX system with a hybrid automatic repeat request (HARQ) mechanism. Furthermore, a queueing analytical model is developed with due consideration of adaptive modulation and coding, the signaling overhead, and the retransmissions of erroneous packets. The arrival process is modeled as the sum of the arrival rate at the initial transmission queue and the retransmission queue, respectively. The service rate is calculated by taking the HARQ retransmissions into consideration. This paper also evaluates the performance of VoIP services in a mobile WiMAX system with and without persistent allocation; persistent allocation is a technique used to reduce the signaling overhead for connections with a periodic traffic pattern and a relatively fixed payload. As shown in the simulation results, the HARQ mechanism increases the system throughput as well as the signaling overhead and the packet delay.

• Journal of KIISE:Computer Systems and Theory
• /
• v.26 no.5
• /
• pp.602-608
• /
• 1999

멀티미디어 서비스를 제공하는 미래의 이동통신 시스템에서는 데이터의 신뢰성 있는 전송을 위해 물리 계층에서 제공하는 프레임 에러율을 감소시켜야한다. 이를 위해 라디오링크프로토콜(RLP : radio link protocol) 계층에서는 ARQ(automatic repeat request)기법을 사용한다. 본 논문에서는 멀티미디어 서비스를 제공하는 차세대 이동통신 시스템에 적용될수 있는 새로운 SR(Selective repeat) ARQ 기법을 제안하고 그 성능을 분석한다. 제안하는 SR 기법은 재전송이 반복될수록 NAK(negative acknowledge)수와 재전송 프레임수를 지수적으로 (exponentially)증가시킴으로써 프레임손실확률을 감소시킨다. 또한 제안한 SR 기법의 성능을 기존의 전형적인 SR 기법 및 IS-707의 SR 기법과 비교하였다. 비교결과, 제안한 SR 기법은 프레임 손실 확률과 프레임 전송지연 측면에서 다른 두 비교대상 Sr 기법들에 비해 더 나은 성능을 제공한다.

• Proceedings of the Korean Society of Tribologists and Lubrication Engineers Conference
• /
• 2001.06a
• /
• pp.100-104
• /
• 2001

The effects of contact configuration and kinematic motion on the wear of ultrahigh molecular weight polyethylene (UHMWPE) were investigated. Two different contact configurations were adopted for wear testing under the two different kinematic motions with un-irradiated UHMWPE specimens. Wear of UHMWPE pins against the linear reciprocating stainless steel disks was 8% higher than that against the uni-directional repeat pass rotating disks. Wear of UHMWPE disks moving in the linear reciprocating motion against stainless steel ball was 37% higher than that moving in the uni-directional repeat pass rotating motion. The results in this study show that the contact configuration and kinematic motion of sliding definitely affect the wear of UHMWPE through the differences in the contact stress states of UHMWPE.

• Parasites, Hosts and Diseases
• /
• v.41 no.4
• /
• pp.221-231
• /
• 2003

To gain information on retrotransposons in the genome of Paragonimus westermani, PCR was carried out with degenerate primers, specific to protease and reverse transcriptase (rt) genes of long-terminal-repeat (LTR) retrotransposons. The PCR products were cloned and sequenced, after which 12 different retrotransposon-related sequences were isolated from the trematode genome. These showed various degrees of identity to the polyprotein of divergent retrotransposon families. A phylogenetic analysis demonstrated that these sequences could be classified into three different families of LTR retrotransposons, namely, Xena, Bel, and Gypsy families. Of these, two mRNA transcripts were detected by reverse transcriptase-PCR, showing that these two elements preserved their mobile activities. The genomic distributions of these two sequences were found to be highly repetitive. These results suggest that there are diverse retrotransposons including the ancient Xena family in the genome of P. westermani, which may have been involved in the evolution of the host genome.

• Proceedings of the Optical Society of Korea Conference
• /
• 1991.06a
• /
• pp.1-1
• /
• 1991

The fabrication of computer components requires a great variety of optical equipment. The patterning of integrated circuits is performed either on step-and-repeat cameras, scanning systems or step-and-repeat systems. The image forming optics used in these machines is quite difficult to design and fabricate. In addtion several layers of patterns must be precisely superposed, and also the illuminators have to provide the final irradiance in the image plane constant to within 1%. Other uses of specialized optical equipment are mass production of chip packages, inspection scanners and laser ablation cameras for polymers. The details of some of these systems will be described with particular ephasis on different optical structures and the use of excimer lasers as light sources.

• Journal of Interdisciplinary Genomics
• /
• v.5 no.2
• /
• pp.13-17
• /
• 2023

KBG syndrome (KBGS) is a multisystem disorder characterized by short stature, distinctive facial features including macrodontia of upper central permanent incisors, and developmental/cognitive delay. It is caused by variants or deletion of Ankyrin Repeat Domain 11 (ANKRD11) located in chromosome 16q24.3. Since its initial report in 1975, KBG syndrome has been recognized as an exceedingly rare disorder. However, recent advancements in genetic diagnostic techniques have led to an increase in both the diagnosis rate and the number of reported cases, contributing to a rapid increase in its global prevalence. We review the clinical aspects of KBGS, including previously reported and newly reported cases, as well as the related genetic patterns discovered so far.