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Epigenetic Responses Programmed by Prenatal Stress : $F_1$ Male Rat Model (출생 전 스트레스에 의해 프로그램된 후생학적 반응 : $F_1$ 수컷 흰쥐 모델)

  • Lee, Sung-Ho
    • Development and Reproduction
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    • v.12 no.2
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    • pp.117-124
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    • 2008
  • The efficient strategies to cope with unpredictable and/or harmful environmental changes have been developed by every organism in order to ensure its survival and continuity of it's own species. As a results, all living things on earth maintain dynamically internal stability via a process termed 'homeostasis' among physiological parameters despite of external environment changes. Stress is an emotional and physical response to threat homeostasis. Stress may have not only transient but rather permanent effect on the organism; recent evidence clearly show that prenatal stress could organize or imprint permanently physiological systems without any change in genetic codes, a process known as 'epigenetic programming'. In this review, a series of reproduction-associated events occurred in prenatally stressed male rats such as alteration in the structure of sexually dimorphic brain regions, modification of neurotransmitter metabolism, changes in reproductive endocrine status, and finally, disorders of sexual behavior will be introduced. The fetal brain is highly sensitive to prenatal programming and glucocorticoids in particular have powerful brain-programming properties. The chronic hyperactivation of fetal brain by maternal stress-induced glucocorticoid input will provide new program via increasing the neuroplasticities. This 'increased neuroplasticities' will be the basis for the 'increased phenotypic plasticities' rendering the organism's better adaptation to environmental challenges. In conclusion, organism who experienced 'harsh' environment in his fetal life seems to give up a certain portion of reproductive competence to make good chance of survival in his future life by epigenetic (re)programming.

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Augmented Plasticity: Giving Morphological Editability to Physical Objects (증강가소성: 물리적 오브젝트에 형태적 편집가능성 부여하기)

  • Lee, Woo-Hun;Kang, Hye-Kyoung
    • Archives of design research
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    • v.19 no.1 s.63
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    • pp.225-234
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    • 2006
  • Product designers sketch various ideas of foreground figures(detail design) onto background figures(basic form) and evaluate numerous combinations of them in the late stages of design process. Designers have to test their ideas elaborately with a high-fidelity physical model that looks like a real product. However, due to the requirements of time and expense in making high-fidelity design models, it is impossible to evaluate such a number of combinatorial solutions of background and foreground figures. Contrary to digital models, physical design models are not easily modifiable and so designers cannot easily develope ideas through iterative design-evaluation process. To address these problems, we proposed a new concept 'Augmented Plasticity' that gives morphological editability to a rigid physical object using Augmented Reality technology and implemented the idea as Digital Skin system. Digital Skin system figures out the position and orientation of object surface with ARToolKit visual marker and superimposes a deformed surface image seamlessly using differential rendering method. We tried to apply Digital Skin system to detail design, redesign of product, and material exploration task. In consequence, it was found that Digital Skin system has potential to allow designers to implement and test their ideas very efficiently in the late stages of design process.

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A Study on the Angle between the Abdominal Aorta and the Superior Mesenteric Artery by 3D Image Reconstruction (3D 영상 재구성을 통한 복부대동맥과 상장간막동맥과의 각도에 관한 연구)

  • Kim, Young-Keun;Choi, Sung-Kwan
    • Journal of radiological science and technology
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    • v.26 no.1
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    • pp.63-70
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    • 2003
  • SMAS(Superior Mesenteric Artery Syndrome) is a disease caused by a chronic obstruction of the duodenum(transverse portion), which is hardly detectable. However, it is known that when the superior mesenteric artery and abdominal aorta form a narrow angle, that the transverse portion of the duodenum is pressed down between the superior mesenteric artery and the abdominal aorta, and that this can lead to obstruction of the duodenum. Measuring this angle is a complicated job using conventional angiography, and results often turns out to be inaccurate. In addition, no attempt has been made to determine the value of this angle in Koreans. In this study, we conducted abdominal CT angiography using MIP(maximum intensity projection) on patients with no clinical evidence of SMAS in order to determine the angle at which the superior mesenteric artery branches from the abdominal aorta by using PC based software(Rapidia ver. 1.2) for the image reconstruction. Accordingly, we found that the mean angle between the abdominal aorta and the superior mesenteric artery was $50.05{\pm}15.87^{\circ}$ on average, and that the angle in men($53.64{\pm}16.57^{\circ}$) is higher than in women($46.46{\pm}14.98^{\circ}$). We hope that the angles determined by our study will serve as an important indicator for detecting SMAS.

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An Optimization Technique of Scene Description for Effective Transmission of Interactive T-DMB Contents (대화형 T-DMB 컨텐츠의 효율적인 전송을 위한 장면기술정보 최적화 기법)

  • Li Song-Lu;Cheong Won-Sik;Jae Yoo-Young;Cha Kyung-Ae
    • Journal of Broadcast Engineering
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    • v.11 no.3 s.32
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    • pp.363-378
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    • 2006
  • The Digital Multimedia Broadcasting(DMB) system is developed to offer high quality audio-visual multimedia contents to the mobile environment. The system adopts MPEG-4 standard for the main video, audio and other media format. It also adopts the MPEG-4 scene description for interactive multimedia contents. The animated and interactive contents can be actualized by BIFS(Binary Format for Scene), the binary format for scene description that refers to the spatio-temporal specifications and behaviors of the individual objects. As more interactive contents are, the scene description is also needed more high bitrate. However, the bandwidth for allocating meta data such as scene description is restrictive in mobile environment. On one hand, the DMB terminal starts demultiplexing content and decodes individual media by its own decoder. After decoding each media, rendering module presents each media stream according to the scene description. Thus the BIFS stream corresponding to the scene description should be decoded and parsed in advance of presenting media data. With these reason, the transmission delay of BIFS stream causes the delay of whole audio-visual scene presentation although the audio or video streams are encoded in very low bitrate. This paper presents the effective optimization technique for adapting BIFS stream into expected MPEG-2 TS bitrate without any bandwidth waste and avoiding the transmission delay of the initial scene description for interactive DMB contents.

2D AND 3D STRUCTURAL STUDY OF RETE RIDGE IN ORAL MUCOSA AND SKIN PADDLE OF VARIOUS FREE FLAPS (구강내 점막과 유리피판에 사용되는 피부의 rete ridge에 관한 2차원 및 3차원적 구조 연구)

  • Ahn, Kang-Min;Chung, Hun-Jong;Kim, Yoon-Tae;Paeng, Jun-Young;Shin, Young-Min;Sung, Mi-Ae;Park, Hee-Jung;Myoung, Hoon;Hwang, Soon-Jung;Choi, Jin-Young;Choung, Pill-Hoon;Kim, Myung-Jin;Lee, Jong-Ho
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.31 no.2
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    • pp.143-149
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    • 2005
  • Objects : With the advancement of tissue engineering techniques, the effort to develop bioartificial mucosa have been actively delivered. The problem we met with this technique is the lack of mechanical strength between kerationocyte layer and dermal layer, where in the normal skin and mucosa, they are tightly bound with rete ridge structure. The purpose of this study is to understand the 2D and 3D structure of rete ridge of mucosa and skin paddle for rendering more biomimetic structure to the artificial mucosa. Materials and Methods : Oral mucosa and skin from the patients who received the oral surgery and maxillofacial reconstruction were harvested. The epidermis was separated from the dermis after treating with dispase for 12-16 hours. H&E staining was performed for 2D(dimensional) structure study and confocal LASER and SEM study were performed for 3D structure. Mean height(Sc) and arithmetic mean deviation(Sa) of all surface height were calculated. Results : The average height of rete ridge of skin flap was between $67.14{\mu}m$ and $194.55{\mu}m$. That of oral mucosa was between $146.26{\mu}m$ and $167.51{\mu}m$. Pressure bearing area and attached gingiva of oral mucosa showed deeper rete ridges. Conclusion : To obtain the adequate strength of artificially cultured keratinocyte skin and mucosa flap, it is necessary to imitate the original skin and mucosa structure, especially rete ridge. Through this study, 2D and 3D rete ridge structure of normal mucosa and skin was obtained. These results can be used as basis for substrate morphology for keratinocytes culture.

Effects of Innovation and Peer Pressure on Color Make-up Behaviors of Middle and High School Students (여중고생의 혁신과 또래압력이 색조화장행동에 미치는 영향)

  • Nam, Hun-Ihl;Song, Kie-You;Lee, Jay
    • CRM연구
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    • v.3 no.2
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    • pp.1-20
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    • 2010
  • Due to the nature of teenage students' common tendency of being drawn to consumption conformity engendered by popular trends, and further expanding their unique collectivist culture, this study presumes that middle and high school female students as well have an influential factor that creates their distinctive trait. This study is intended to investigate the students' personal characteristics and effects of social reference groups, and further scrutinize how these influences transcends to deviant make-up behaviors. A total of 297 subjects, middle and high school female students, participated in a survey, using questionnaires focused primarily on the degrees of color makeup and the influences imposed by classmates. The findings of the study are as follows. First, regarding makeup behavior displayed by middle and high school female students, social self-esteem had positive influence on innovation and peer pressure. Second, perceived visibility conversely had negative impacts on innovation and peer pressure. This indicates that if perceived visibility is at a salient level, this already signifies lack of innovation. Third, makeup innovation and peer pressure demonstrated by middle and high school students all showed positive influence on their makeup behaviors. Additionally, peer pressure, in comparison to innovation, had greater influence on makeup behaviors, which indicates that peer pressure play a great role in makeup behavior of middle and high school students. Fourth, makeup behaviors showed strong impacts on makeup satisfaction and rendering deviant behaviors, which indicates that a new direction and perspective regarding middle and high school students' makeup behavior is critical.

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Study on the Synthesis of the Binder for Antistatic Coating Applicable under High Voltage (고전압에 적용 가능한 대전방지 코팅제용 바인더의 합성에 관한 연구)

  • Kim, Jae Young;Yang, Hee Jun;Pak, Na Young;Choi, Young Ju;Lee, Seong Min;Chung, Dae-Won
    • Applied Chemistry for Engineering
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    • v.24 no.2
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    • pp.196-200
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    • 2013
  • We conducted investigation on polymeric binders for anti-static coating agent which can maintain stability under the high-voltaic condition. Various polyesters composed of polyethylene glycol (PEG) and polypropylene glycol (PPG) were synthesized and studied in term of the variation in the surface resistance of the film made from coating solution composed of a conductive polymer and these polyesters as a binder. We found that the surface resistance displayed $10^7{\sim}10^8{\Omega}/{\square}$ regardless of chemical composition of binders under the potential of 10 V. Whereas, the surface resistance surged to higher than $2{\times}10^{10}{\Omega}/{\square}$ when 1000 V was applied, rendering it improper for anti-static purpose. When 1,4 butanediol (BD) was incorporated into polyesters ([PEG]/[PPG]/[BD] = 25.0/67.5/7.5), the surface resistance showed $2.8{\times}10^9{\Omega}/{\square}$ under 1000 V, acceptable for anti-static application. These observations may indicate that the hydrophobic nature of BD makes a significant contribution to the surface resistance at a high positive potential.

Implementation of Integrated Player System based on Free-Viewpoint Video Service according to User Selection (사용자 선택에 따른 자유 시점 비디오 서비스 기반의 통합 플레이어 시스템 구현)

  • Yang, Ji-hee;Song, Min-ki;Park, Gooman
    • Journal of Broadcast Engineering
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    • v.25 no.2
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    • pp.265-274
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    • 2020
  • Free-viewpoint video service is a technology that allows users to watch at any angle, location and distance through interaction. In this paper, the free-viewpoint video services are defined in four viewing modes: Inward view, outward view, 3D object view and first person view. And we developed and implemented a new integrated program that plays all the suggested views. In the contents of girl band performances and basketball games, multi-view cameras suitable for each viewing mode are installed to acquire media, and data stored on the server is streamed over the network, making it available for viewing. Users can freely choose four viewing modes, space location, angle and so on, and the media data such as images and sounds are provided to them by rendering appropriately for the selected the viewpoint. Our system is expected to be a scalable free-viewpoint video service player as well as provide users with immersion and presence by combining various viewing modes.

A Study on 3D Character Design for Games (About Improvement efficiency with 2D Graphics) (3D Game 제작을 위한 Character Design에 관한 연구 (3D와 2D Graphics의 결합효율성에 관하여))

  • Cho, Dong-Min;Jung, Sung-Hwan
    • Journal of Korea Multimedia Society
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    • v.10 no.10
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    • pp.1310-1318
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    • 2007
  • First of all, What was the modeling technique used to model 3D-Game character? It's a technique developed along several years, by experience... here is the bases Low polygons characters I always work in low polygon for two reasons -You can easily modify a low-poly character, change shapes, make morph for facial expressions etc -You can easily animate a low-poly character When the modeling is finished, Second, In these days, Computer hardware technologies have been bring about that expansion of various 3D digital motion pictured information and development. 3D digital techniques can be used to be diversity in Animation, Virtual-Reality, Movie, Advertisement, Game and so on. Besides, as computing power has been better and higher, the development of 3D Animations and Character are required gradually. In order to satisfy the requirement, Research about how to make 3D Game modeling that represents Character's emotions, sensibilities, is beginning to set its appearance. 3D characters in 3D Games are the core for the communications of emotion and the informations through their facial expression and characteristic motions, Sounds to Users. All concerning about 3D motion and facial expression are getting higher with extension of frequency in use. Therefore, in this study we suggest the effective method of modeling for 3D character and which are based on 2D Graphics.

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Implementation of a Person Tracking Based Multi-channel Audio Panning System for Multi-view Broadcasting Services (다시점 방송 서비스를 위한 사용자 위치추적 기반 다채널 오디오 패닝 시스템 구현)

  • Kim, Yong-Guk;Yang, Jong-Yeol;Lee, Young-Han;Kim, Hong-Kook
    • 한국HCI학회:학술대회논문집
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    • 2009.02a
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    • pp.150-157
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    • 2009
  • In this paper, we propose a person tracking based multi-channel audio panning system for multi-view broadcasting services. Multi-view broadcasting is to render the video sequences that are captured from a set of cameras based on different viewpoints, and multi-channel audio panning techniques are necessary for audio rendering in these services. In order to apply such a realistic audio technique to this multi-view broadcasting service, person tracking techniques which are to estimate the position of users are also necessary. For these reasons, proposed methods are composed of two parts. The first part is a person tracking method by using ultrasonic satellites and receiver. We could obtain user's coordinates of high resolution and short duration about 10 mm and 150 ms. The second part is MPEG Surround parameter-based multi-channel audio panning method. It is a method to obtain panned multi-channel audio by controlling the MPEG Surround spatial parameters. A MUSHRA test is conducted to objectively evaluate the perceptual quality and measure localization performance using a dummy head. From the experiments, it is shown that the proposed method provides better perceptual quality and localization performance than the conventional parameter-based audio panning method. In addition, we implement the prototype of person tracking based multi-view broadcasting system by integrating proposed methods with multi-view display system.

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