• Title/Summary/Keyword: release characteristics

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Thermal Characteristics of Living Leaves in Pinus Densiflora with Heat Flux (복사열 증가에 따른 소나무 생엽의 열적특성 분석)

  • Park, Young-Ju;Lee, Hae-Pyeong
    • Journal of the Korean Society of Hazard Mitigation
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    • v.10 no.5
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    • pp.75-82
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    • 2010
  • To study the combustion characteristics of forest fuel by fire intensity, the experiment of combustion characteristics on Pinus Densiflora living leaves, which is the weakest species to the forest fire, was delivered, using variables of heat flux(25 kW/$m^2$, 50 kW/$m^2$, 75 kW/$m^2$). With the equipment of Cone calorimeter, the characteristics of ignition, heat, smoke release, CO and $CO_2$ release, and mass loss were analyzed. Pinus Densiflora living leaves containing moisture of 60.66% were not ignited at the heat flux of variables 25 kW/$m^2$, 50 kW/$m^2$, 75 kW/$m^2$. In proportion to the heat flux value, heat release amount and heat release rate reached maximum value rapidly: higher variables came to the maximum by the half rapidity and the maximum value were twice higher than the former lower variables respectively. As for the smoke release, the less heat flux the variable had, the more smoke release it had, due to incomplete combustion. The release amount of CO and $CO_2$ had more maximum value as the heat flux increased and more radiant heat meaned more carbon oxide. When the forest fire breaks out, therefore, a great amount of CO and $CO_2$ will be released by Pinus Densiflora.

Usage Characteristics of Publicly-Available Accidental Release Models (주요 누출사고 예측 모델의 사용 특성 비교)

  • 정수희;윤도영;김영성
    • Journal of Korean Society for Atmospheric Environment
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    • v.15 no.5
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    • pp.687-696
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    • 1999
  • Characteristics of four publicly-available accidental release models, ALOHA, SLAB, HGSYSTEM, and DEGADIS, are compared. These models are world-widely used and recently recommended by the Chemical Dispersion and Consequence Assessment(CDCA) Working Group of the United States as models applicable to generally broad safety-basis documentation applicatons. Four release scenarios are assumed by referring to the usage and storage conditions of toxic substances in the field as well as the USEPA model guideline(1993). Sensitivity of impact radius by varying meteorological conditions is tested in typical and worst-case meteorological conditions. The results show that ALOHA generally gives conservative estimates and the results from HGSYSTEM are sensitive to variations in meteorological conditions.

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A study on release characteristics and forms of phosphorus in sediments (퇴적물에서의 인의 용출특성과 존재형태에 관한 연구)

  • 김은호;김형석
    • Journal of environmental and Sanitary engineering
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    • v.17 no.1
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    • pp.75-80
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    • 2002
  • This study was carried out to investigate release characteristics of phosphorus with DO, pH and temperature, to suppose its behaviour with time using mathematical model, and to under-stand its forms with pH. Released SRP was in inversely proportional to DO and it did few release in initial aerobic conditions, but it did actively with decreasing DO concentration. Also, its release was increased with increasing pH and temperature. It was found that relation between time and released SRP concentration was zero order reaction. As compared with k values in various pH and temp., they was $k_{15}>k_{25}$ in pH 6 but was $k_{15} in pH 7 and 8. Considering forms of phosphorus with pH, Resdi.-P & NAI-P increased but Ads.-P & Apt.-P decreased with increasing pH.

Effects of Emulsified Fuel on Combustion Characteristics in a Diesel Engine (디젤기관에 있어서 에멀젼연료 연소특성에 미치는 영향)

  • Lim, J.K.;Cho, S.G.;Hwang, S.J.;Yoo, D.H.
    • Journal of Power System Engineering
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    • v.11 no.1
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    • pp.51-55
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    • 2007
  • A study on combustion characteristics using emulsified fuel in a diesel engine were performed experimentally. In this paper, the experiments were performed at engine speed 1800rpm, emulsion ratios were 0%, 10%, 20%, and main measured items were specific fuel consumption, cylinder pressure, rate of pressure rise, rate of heat release etc. The obtained conclusions were as follows. 1) Specific fuel consumption increased maximum by 19.8% at low load, but was not affected at full load. 2) Rate of pressure rise and rate of heat release were about the same in the case of 10% and 20% of emulsion ratio. 3) Cylinder Pressure increased 9.6%, rate of pressure rise increased 53.4% in case of emulsion ratio 20% at full load. 4) Rate of heat release increased 72.4% in case of emulsion ratio 20% at full load.

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Drug Release Characteristics of Famotidine-Cationic Exchange Resin Complexes and Their Pharmacokinetics in Rats (파모티딘-양이온 교환수지 복합체의 약물방출 특성 및 흰쥐에서의 체내동태)

  • Shin, Dong-Sun;Song, Woo-Heon;Choi, Young-Wook
    • Journal of Pharmaceutical Investigation
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    • v.27 no.4
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    • pp.313-321
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    • 1997
  • Ion exchange resin complexes of famotidine have been prepared by the reaction of famotidine solution with activated ion exchange resins. Complex formation efficiency between famotidine and ion exchange resin was about $80{\sim}90%$ in average, calculated by HPLC determination. Drug release characteristics from the resin complexes were evaluated by the modified percolation method. Famotidine release was dependent on the type of ion exchange resins. In the case of weakly acidic resin complexes, the cumulative released amount of famotidine was more than 90% for 1hr in pH 1.2 buffer solution. However, in the case of strongly acidic resin complexes, it was less than 5% for 3hr in the same medium. Strongly acidic resins revealed some advantages over weakly, acidic resins for overcoming instability of famotidine in gastric juice. In addition, strongly acidic resin complexes showed controlled release of famotidine in pH 6.8 buffer solution, showing the result of about 60 to 70% of drug release for 5hr. After oral administrations of famotidine-resin complexes to rats as dose of 40 mg equivalent/kg, the pharmacokinetic parameters of famotidine were obtained by model independent analysis and compared with those of famotidine solution or suspension. $C_{max}$ of famotidine-resin complex was lower than that of famotidine solution or suspension. MRT, MAT, and MDT of the complexes were greater than those of famotidine solution or suspension. From these results, it was expected that famotidine was released slowly from the complexes and absorbed continuously into systemic circulation. It was recognized that drug release from the complexes was the rate-limiting step in drug absorption, since there were close correlations between in vitro drug release and in vivo pharmacokinetic parameters.

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Characteristics of Release Rate of Nutrients from Sediment in Lake Paldang and Lake Cheongpyeong (팔당호와 청평호 퇴적물에서 영양염류 용출 특성)

  • Lee, Kyoo;Choi, Myung-Jae;Park, Hae-Kyung;Lee, Jang-ho
    • Journal of Korean Society on Water Environment
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    • v.25 no.5
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    • pp.742-749
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    • 2009
  • To examine the characteristics of the nutrient release from the sediments in two reservoirs, Lake Paldang and Lake Cheungpyeung, we analyzed physical and chemical properties of the sediments and calculated the nutrient release rates from the sediments. The particle properties of sediments in Lake Paldang changed from silt to sand after summer rainy season, especially in the water area of the Kyeungan River where the water depth was shallow and the width of river was narrow. The sediments in Lake Cheungpyeung had higher contents of silt and clay than in Lake Paldang, and the particle size was not much different before and after rainfall. The release rates of nutrients in two lakes varied with the kind of nutrients and the season. The release rates of DTN and ${NH_4}^+-N$ in Lake Paldang were faster in spring than autumn. But the Lake Cheungpyeung showed similar values of release rates before and after summer rainy season. ${NO_3}^--N$ and phosphorous were not released from sediments or were absorbed into sediments all the time in two lakes. Compared with other lakes, the sediments of two lakes consisted of bigger particles and had a lower organic matters content than other lake-type reservoirs. Due to the short hydraulic retention time and no stratification throughout the year in Lake Paldang and Lake Cheungpyeung, the release rates of nutrients from sediment in these reservoirs were lower than other lakes and this seems to be a typical characteristic of river-type reservoirs.

Mucoadhesion, Swelling and Drug Release Characteristics of Hydroxypropylcellulose/Carbopol Solid Dispersions (히드록시프로필셀룰로오스/카르보폴 고체분산체의 점막부착성과 팽윤 및 약물방출특성)

  • Kim, Sang-Heon;Yang, Su-Geun;Shin, Dong-Sun;Lee, Min-Suk;Choi, Young-Wook
    • Journal of Pharmaceutical Investigation
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    • v.24 no.3
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    • pp.155-165
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    • 1994
  • Some mucoadhesive polymers such as hydroxypropylcelluose (HPC) and carbopol-934 (CP) have been employed for the preparation of mucoadhesive polymeric systems, and their physical properties including mucoadhesion, swelling, and drug release were evaluated. A new simple experimental technique that can quantitatively measure the bioadhesive properties of various polymeric systems has been developed by the methods of detachment force test. As the polymeric systems, the discs of freeze-dried HPC/CP solid dispersions were prepared. The mucosa used in these tests were upper, middle, and lower parts of small intestine of male rats weighing $300{\sim}350\;g$. Detachment forces were increased as the mole fraction of CP increased in discs of HPC/CP solid dispersions. In the points of intestinal site dependence of mucoadhesion, the solid dispersions revealed non-specific mucoadhesion to the intestine. Swelling and drug release characteristics of mucoadhesive polymeric systems were studied extensively to find out the feasibility for the oral controlled delivery systems. Swelling ratio, expressed as the final height/initial height, has been determined in various pH buffer solutions. Hydrochlorothiazide (HCT) was employed as a model drug for release study. Apparent swelling and drug release rate constants, $K_s$ and $K_r$ respectively, were obtained from the square-root time plot of either swelling ratio or released amount of drug, particularly for the time periods before reaching the equilibrium. As a result, the swelling ratio of HPC/CP solid dispersions was increased as the weight percentage of CP increased. Similarly, the release of HCT from the solid dispersions was dependent on pH changes and CP contents, resulted in the slower release of HCT with the increases of pH and CP contents.

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Alginate/Carboxymethyl Scleroglucan Hydrogels for Controlled Release of Protein Drugs

  • Lee, Chang-Moon;Jeong, Hwan-Jeong;Kim, Dong-Woon;Lee, Ki-Young
    • Macromolecular Research
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    • v.16 no.5
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    • pp.429-433
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    • 2008
  • Alginate/carboxymethyl scleroglucan (CMSG) hydrogels were suggested as a novel carrier for the controlled release of protein drugs. The drug release characteristics of alginate hydrogels were improved by CMSG addition. Scleroglucan (Sclg) was carboxymethylated using monochloroacetic acid in aqueous alkaline medium. Alginate/CMSG hydrogels were prepared by dropping the mixture solution of alginate/CMSG into calcium chloride solution. The swelling behaviors and drug release characteristics of the hydrogels were investigated in the buffers of pH 1.2 or 7.4. As the CMSG content increased in the hydrogels, the swelling ratio of the alginate/CMSG hydrogel increased rapidly in the buffer of pH 7.4. At pH 1.2, however, the swelling ratio significantly decreased compared to that at pH 7.4. According to in vitro release tests, only 15% of ovalbumin, investigated as a model protein drug, was released from the alginate/CMSG hydrogels at pH 1.2 within 6 h. At pH 7.4, however, the drug release significantly increased due to the rapid swelling of the hydrogels. The release and swelling behaviors of the hydrogels could be controlled by changing the CMSG content in the hydrogels. These results supported the use of alginate/CMSG hydrogels as a suitable carrier for the controlled release of protein drugs in a pH responsive manner.

Release Characteristics of Sulfadiazine Using Chitosan Matrices (키토산 매트릭스를 이용한 Sulfadiazine의 방출 특성)

  • 문일식;나재운
    • KSBB Journal
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    • v.11 no.6
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    • pp.676-680
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    • 1996
  • The characteristics of controlled drug release were studied for a biodegradable drug delivery system. A biodegradable chitosan matrix was prepared after swelling chitosan with 10%-acetic acid and adding sulfadiazine. The release behavior of sulfadiazine from the chitosan matrix was studied using the Higuchi's diffusion controlled model in phosphate buffer solutions of pH 7.4 and pH 1.2. The drug release time was delayed by increasing the content of sulfadiazine. The drug release at pH 7.4 was more delayed than that at pH 1.2. The reason is that chitosan has greater swelling abilities at low pH than at high pH. The apparent release rate constant(K) increased as the concentration of drug increased. In shoat, the formulation the biodegradable chitosan matrix to suppress the burst effect of drug release mechanism, which led to a sustained release pattern.

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The evaluation of pollution level and release characteristics by inner productivity in the sediment of lake (호소 퇴적물 내부생산성 오염도 영향 평가 및 용출특성에 관한 연구)

  • Lee, Sang Eun;Choi, I Song;Lee, Sang Keun;Lee, In Ho;Oh, Jong Min
    • Journal of Environmental Impact Assessment
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    • v.21 no.1
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    • pp.81-91
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    • 2012
  • In this study, it is grasped the status of nutrients through an investigation of release characteristics and physicochemical properties of sediments on reservoir. And then the effect of sediments is evaluated on the water quality in reservoir. In the results of physicochemical analysis, the pollution level of midstream is the highest, which shows the traits that the water is more deeper and takes place a deposition consistently. Then, the pollution level of upstream is higher than downstream's because inflow has influence on the upstream directly. The downstream is located near tidal gate so that the soil particles can be moved easily and are difficult to be deposited due to the distribution of seawater by control of tidal gate. Therefore, the downstream is showed the lowest pollution level than the others. Also, the concentration of SOD(Sediment Oxygen Demand) in the upstream which is influenced on the effect of inflow is highest than the others. When it analyzes under anaerobic and aerobic condition to understand the release characteristic of sediment, it shows that the release rate is low or negative under the aerobic condition. Whereas the release rate is usually positive under the unaerobic condition relatively. According to these results, it is necessary to maintain the proper environmental factors of water body for decreasing the release rate of sediment. Because the release rate is changeable under the different condition of water body. Therefore, proper strategies are required for increasing the self-purification of water as well as keeping the aerobic condition of sediment and managing a sediment layer directly to control the inner-pollution by the sediment of reservoir.