• 동의생리병리학회지
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• 제19권2호
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• pp.490-494
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• 2005

The purpose of this was investigate the possibility of medicinal plants application as an edible functional food resources. We arried out to develop a beverage by using Nelumbo nucifera and we examined the nutritional characterics. Also we examined the effects of drink on physiological function in aorta relation. Thus, the effect of developed beverage on phenylephrine induced contraction of isolated rat thoracic aorta. Contractile force was measured with force displacement thansducer under 1.5g loading tension. Brix, pH and titratable acidity of developed drink were 12.25%, 4.5 and 0.092%. The approximate nutritional composition of beverage was carbohydrate, 9.40%, crude protein, 0.30%, crude fat, 0.25% and ash, 0.15%. Also insoluble fiber and soluble fiber were 1.30%, 0.80%. Developed beverage contained Na(11.45 mg%), K(6.87 mg%), Ca(2.53 mg%). The contraction forces by injection of phenylephrine in isolated thoracic aorta were significantly law in each beverage treatment groups compared with control group. These results that developed drink with medicinal plants can be used as a functional material to decrease aorta contraction.

• 동의생리병리학회지
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• 제16권1호
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• pp.62-66
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• 2002

Hypertension is not only a well-established cardiovascular risk factor but also increase the risk of atherosclerosis. Most studies conducted to investigate the effectiveness of treatment for cardiovascular disease such as hypertension have focused primarily on conventional drug and physiotherapeutic treatments. BanhabackchulChunma-tang(半夏白朮天麻湯:BCT) is popular herbal medicine used in clinic for the treatment of various symptoms of drulatory disorders and weakness of digestive system, including anorexa and nausea with vertigo, severe headache, vomiting and so on. However, the mechanisms underlying its efficacy are unknown. This study investigated the effects of BCT as an alternative medication on the contraction induced by phenylephrine and KCI in rat thoratic aorta. BCT revealed siginificant relaxation on phenylephrine-induced arterial contraction, but revealed noncompetitive effect on concentration responses of phenylephrine-induced contraction. Treatment of N-L/sup ω/ -argine methyl ester(L-NAME) and methylene blue(MB)(10/sup -5/M) reduced the relaxation of BCT. BCT also increased in vitro NO production. It suggest that the relaxation effect of BBT is related with NO pathway, becausse the effect of L-NAME and MB are due to inhibition of NO synthesis from endothelial cells. These results indicate that BCT would be effective in hypertension treatment and its mechanism of relaxtion on arterial contraction is likely to be related with NO production, blocking of α-receptor and signal transduction after receptor activation.

• 전산구조공학
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• 제9권1호
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• pp.151-159
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• 1996

구조용 콘크리트의 비선형 거동을 예측하기 위하여, 압축강도 연화현상, 거시적 및 회전균열모델등의 내용을 포함하고 있는 압축장 응력장 이론(CFT)에 근거한 유한요소법이 개발/제시되었다. 또한, 이와 관련하여 CFT가 암시하는 탄젠트 및 세칸트 재료강성이 반복계산해법의 관점에서 정의/논의되었다. 최종적으로 계산상의 효율성 증대 및 최대하중 이후의 거동 포착에 주안점을 두어 초기재료 강성을 채택한 변위증분법 논리 및 빠른 수렴을 위한 Over-Relaxtion방법이 Isoparametric계의 8-Node요소에 포함/유도되었다. 이와 같이하여 제시된 비선형 해석 프로그램 NASCOM은 응력 혼돈지역에 위치하는 콘크리트 평면요소의 하중 지지능력, 탄성범위 이후의 변형 특성, 균열양상 및 보강근의 항복범위등의 예측을 가능하게 하였다. NASCOM의 제한된 검증을 위하여, Cervenka의 판넬 시험결과에 대한 하중지지능력 및 변형이력등을 예측한 결과가 전체적인 의미에서 실험결과와 상응하는 일치를 나타내었다.

• 대한기계학회논문집B
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• 제37권7호
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• pp.683-693
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• 2013

본 연구에서는 혼성 격자볼츠만 방법(HLBM)을 이용하여 상판이 일정한 속도로 움직이는 공동 형상 내부에서의 혼합 특성에 대하여 수치적으로 연구하였다. 먼저, 공동 형상에서 기존의 신뢰성 있는 유동장 결과와의 비교를 통해 LB-SRT 모델과 LB-MRT 모델의 신뢰성을 검토하였다. 두 모델 모두 기존의 연구결과와 유사한 결과를 보였으나, LB-MRT 모델이 LB-SRT 모델보다 높은 Re수에서는 수치적 안정성이 높은 것을 확인하였다. 수치적 안정성이 좋은 LB-MRT 모델을 토대로 유한차분법을 적용한 HLBM을 이용하여 공동 형상 내부에서의 농도장을 수치 해석하였다. Re수와 Pe수를 변화하여 공동 형상 내부의 혼합 특성과 물질 전달 형태에 대하여 파악하였다.

• 지구물리와물리탐사
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• 제1권1호
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• pp.19-24
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• 1998

본 논문은 3차원 굴절탄성파 탐사시 얻게 되는 굴절주시를 이용하여 경사진 지층경계면상 속도 분포를 추정하는 방법을 수립코자 수행한 연구를 요약한 것이다. 자료획득은 토모그래피 기법에, 주시 역산은 under-relaxation ART 기법에 의거하였다. 모델은 경사 2층 구조이며, 관련된 매개변수는 지반조사시 만나게 되는 지층을 염두에 두고 선정하였다. 하부 지층에는 수직으로 저속도 혹은 고속도 이상대가 존재하며, 따라서 탐사의 주목적은 이러한 이상대를 탐지하는 것이다. 몇 가지 경우에 대하여 역산을 수행한 결과, 경사 지층 경계면의 경우, 경사 보정을 수행치 않으면 역산 결과는 판독이 어렵거나, 판독하더라도 착오를 일으킬 수 있다는 사실을 확인하였다. 종래 심도 추정을 위한 굴절탄성파 탐사에서, $15^{\circ}$ 이내의 경사지층 경계면을 평균적으로 수평이라고 가정해도 큰 오차가 나지 않는다는 사실을 상기할 때, 앞에 말한 사실은 특이한 일이다.

• 대한간호학회지
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• 제22권4호
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• pp.526-551
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• 1992

The purpose of this study was to identify the commonalities of various nursing interventions and effective intervention methods in each intervention through analysis and synthesis of many accumulated research papers. The study analyzed the effects of various nursing interventions on anxiety and /or stress. For this purpose, 64 experimental studies with randomized or nonequivalent control group pre-test-posttest design were selected from journals of medical and nursing schools, the Korean Nurse, the Korean Nurses' Academic Society Journal, the Cetnral Journal of Medicine, the New Medical Journal, the Nurse Monthly, and from theses and dissertations conducted from 1970 to 1991. The selected studies nor classified according to three characteristics : 1) the research samuel, 2) types and methods of nursing interventions, and 3) statistical tests. The following analysis was done : 1) Confirmation of the accuracy of data drawn from each study by paired review, 2) Estimation of the homogenity of pre-test scores of the dependent variable between control and experimental groups warranted the effect size of post-scores, 3) If the homogenity of pre-test scores did not warrant, the change scores from pre-test to post-test were used to estimate the effect size, 4) Use of the effect size of each study among homogenious studies was tested for each intervention method, such as relaxation, information, and touch and /or support. Finally, for the studies not showing homogenity, an ANOVA test was used to identify patterns for each intervention. Some findings are summarized as follow : The effect sizes for relaxation and information were greater than those for touch and /or supportive technique. Studies using random assignment had greater effect sizes than nonrandomized sample studies using the same intervention. For healthy people, group education was more effective than individual teaching. However, for patients, relaxation and touch and /or supportive techniques given on individual basis were more effective than when given in a group situation. Measuring anxiety and stress by biological indicators was less effective than by self-report. Budzynski's relaxation method was the most effective. The more frequently the techniques applied, the larger the effect size. On the bases of these findings, the following recommendations were made : 1. A combination of information, relaxtion, and touch-supportive techniques should be used for greater effect in reducing the level of anxiety and /or stress. 2. Information is the first choice of intervention to reduce the level of anxiety and /or stress of healthy People : other interventions may be added depending on the conditions of the subjects.