• Journal of Radiation Protection and Research
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• v.28 no.3
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• pp.189-197
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• 2003

The Level 3 PSA being termed accident consequence analysis is defined to assess effects on health and environment caused by radioisotopes released from severe accidents of nuclear power plants. In this study consequence analysis on health effects depending on release characteristics of radioisotopes has been peformed using the 3 MACCS code in severe accidents. The results of this study may contribute to identifying the relative importance of various parameters occurred in consequence analysis as well as to assessing risk reduction accident management strategies. Especially three parameters for the purpose of consequence analysis, such as the release height, the heat content, and the duration time, are used to analyze the variation of early fatalities and latent cancer fatalities. Also, in this study risk assessment using the concept, 'products of uncertainty and consequences', has been performed using consequence of MACCS and frequency on source term category 19 scenarios from IPE (Individual Plant Examination) analysis.

• Nuclear Engineering and Technology
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• v.49 no.2
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• pp.411-425
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• 2017

Using a probabilistic safety assessment, a risk evaluation framework for an aircraft crash into an interim spent fuel storage facility is presented. Damage evaluation of a detailed generic cask model in a simplified building structure under an aircraft impact is discussed through a numerical structural analysis and an analytical fragility assessment. Sequences of the impact scenario are shown in a developed event tree, with uncertainties considered in the impact analysis and failure probabilities calculated. To evaluate the influence of parameters relevant to design safety, risks are estimated for three specification levels of cask and storage facility structures. The proposed assessment procedure includes the determination of the loading parameters, reference impact scenario, structural response analyses of facility walls, cask containment, and fuel assemblies, and a radiological consequence analysis with dose-risk estimation. The risk results for the proposed scenario in this study are expected to be small relative to those of design basis accidents for best-estimated conservative values. The importance of this framework is seen in its flexibility to evaluate the capability of the facility to withstand an aircraft impact and in its ability to anticipate potential realistic risks; the framework also provides insight into epistemic uncertainty in the available data and into the sensitivity of the design parameters for future research.

• Journal of Environmental Impact Assessment
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• v.6 no.1
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• pp.93-103
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• 1997

LHR(Landfill Site Hazard Ranking Model) was developed for ranking the relative hazard of landfill sites by using the method of value-structured approach. LHR consists of combining a multiattribute decision-making method with a Qualitative risk assessment approach. A pairwise com parisian method was applied to determine weights of landfill site factors related. To determine the hazard of landfill site, hydrogeological factors, waste characteristics factors and receptors factors were evaluated by LHR. LHR can help decision-makers prioritization of remediation of landfill sites through the relatively convenient and concise evaluation method of landfill site features related. LHR focuses mainly on pathways of groundwater and surfacewater for evaluating landfill hazard to receptors including humans. To validiate the applicability of LHR, Nanjido Landfill site, Metropolitan Landfill site, and Hwasung Landfill site were evaluated.

• Korean Chemical Engineering Research
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• v.56 no.3
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• pp.335-342
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• 2018

Various technologies to cope with the energy and environmental issues related to the chemical and electric power industry are in development and demonstration stage. Especially, the absorption process of carbon dioxide ($CO_2$) using amine solution is a key technology of the $CO_2$ capture and storage (CCS). In this study, we identify the major risk factors and suggest strategies for safety improvement by analyzing and assessing commercial the amine-based $CO_2$ separation process. HAZOP method was used to assess the risk for the process. We provide facilities and operational strategies to mitigate or eliminate major risk factors by assessing the relative ranks of identified risk factors using a risk matrix.

• Journal of Environmental Impact Assessment
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• v.6 no.2
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• pp.113-121
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• 1997

LHR(Landfill Hazard Ranking Model) was developed for assessing the relative hazard of landfills by using the method of value-structured approach. LHR consists of combining a multiattribute decision-making method with a qualitative risk assessment approach. A pairwise comparision method was applied to determine weights of landfill factors related. To prove the validity of weights allocation of landfill hazard evaluation factors, sensitivity analysis was applied. Firstly, the impact on landfill hazard score according to variations of weights of landfill hazard factors was analyzed. Secondly, the impact on landfill hazard score according to conditions change of landfill hazard factors was analyzed. As a result of sensitivity analysis, LHR composite scores are largely influenced by some factors following sequential order such as waste volume, proximity to sensitive environments, containment facilities, distance from drinking water supplies, and waste toxicity. The relative order of landfill hazard evaluated by LHR is not influenced by the weights change of individual factors. Therefore, LHR seems to be a credible model to determine priorities of landfill remediation based on the vulnerability of water resources.

• Safety and Health at Work
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• v.5 no.3
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• pp.125-130
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• 2014

Background: Construction industry is among the most hazardous industries, and needs a comprehensive and simple-to-administer tool to continuously assess and promote its health and safety performance. Methods: Through the study of various standard systems (mainly Health, Safety, and Environment Management System; Occupational Health and Safety Assessment Series 180001; and British Standard, occupational health and safety management systems-Guide 8800), seven main elements were determined for the desired framework, and then, by reviewing literature, factors affecting these main elements were determined. The relative importance of each element and its related factors was calculated at organizational and project levels. The provided framework was then implemented in three construction companies, and results were compared together. Results: The results of the study show that the relative importance of the main elements and their related factors differ between organizational and project levels: leadership and commitment are the most important elements at the organization level, whereas risk assessment and management are most important at the project level. Conclusion: The present study demonstrated that the framework is easy to administer, and by interpreting the results, the main factors leading to the present condition of companies can be determined.

• Anatomy and Cell Biology
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• v.56 no.4
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• pp.469-473
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• 2023

Anomalies of anterior cerebral artery (ACA) include aplasia, hypoplasia and variations in number. Magnetic resonance angiography (MRA) is a non-invasive diagnostic technique for assessment of anomalies of cerebral arteries. The aim of the study was to determine the role of MRA in detection of variants of ACA in adults. This study is an observational retrospective study. This study included forty-nine adult cases (28 males and 21 females), mean age 48±12.9 SD with anomalies of ACA in MRA. Magnetic resonance imaging of the brain and MRA were done to all patients. Cerebral MRA and magnetic resonance images were evaluated for frequency and distribution of variants of anterior cerebral arteries, associated aneurysms and infarctions. Odds ratios (ORs) and relative risk were calculated to determine risk of occurrence of cerebral infarctions in patients with anomalies of ACA. Hypoplasia of ACA was the commonest anomaly of ACA (51% of cases). Risk of occurrence of cerebral infarctions was higher in cases with azygos variant (OR, 3.3; P=0.35) than in those with hypoplastic ACA (OR, 2; P=0.58). MRA was highly reliable in identification of different variants of ACA and concomitant vascular changes.

• Journal of Environmental Impact Assessment
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• v.2 no.2
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• pp.59-71
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• 1993

Evaluation methods are employed in environmental impact assessment to choose between different project site, to determine the required measures to compensate impact and to decide whether the environmental impacts are more important than the social or economic effects of a project. The main obstacles that restrict use of quantitative evaluation method are a Lack of knowledge about the environmental effects (e.g. if impacts on wildlife or landscape amenities are predicted) and the relative importance of economic and social issues compared with nature conservation stability of ecosystem or landscape beauty. In Germany, the most common method for site planning is the "ecological risk analysis". It is a kind of multi-criteria-decision-method based on quantitative and qualitative description and ordinal ranking. The various kinds of "ecological balancing methods" that are more recently developed (within the last decade) to quantify the required amount for compensatory measures instead often use cardinal figures to express the value of ecosystems, the intensity of impacts, the need for additional measures to compensate for long recuperative periods when restoring ecosystems and so on. There are still only a view attempts to quantify decisions between environmental and socio-economic issues. Multicriteria-analysis as well as cost-benifit-analysis was used. Some new approaches which are still in a preliminary status are based on contingent valuation and on calculations for compensatory payments (instead of compensatory measures).

• The Journal of Engineering Geology
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• v.28 no.3
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• pp.379-395
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• 2018

A walking trail environment can be divided into the upper part of the trail, the trail itself, and the lower part of the trail. In this study, based on field investigations, we developed a risk index for trails by considering human/societal factors that affect each of these three trail environments. A checklist was developed for field investigations, and checklist items were scored through relative importance analysis. The relative weights of items were analyzed using the AHP (Analytic Hierarchy Process) technique, revealing that the upper environment of a trail is twice as important as the rest of the environment. The importance and score of items belonging to each environment were determined. We define the risk index as the sum of the item scores. Weights were added using data from existing investigations including landslides risk rating and designated risk steep slopes. The risk index has a maximum value of 200, and the maximum and minimum calculated scores of 335 risk sections were 159 and 64.2, respectively. As a result of comparative analysis between field observations and risk index calculations, most sections at relatively low risk had risk values less than 100, and sections with high risks or that had been the site of accident yielded scores that exceeded 140.

• Korean Journal of Clinical Pharmacy
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• v.21 no.2
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• pp.90-99
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• 2011

Health Insurance Review & Assessment Service (HIRA) claims database has a high potential to detect signals of new drug interactions. The aim of this study was to evaluate the usefulness of information component (IC) and relative risk (RR) as a tool for signal detection, and to analyze the possible drug interactions caused by clopidogrel using HIRA claims database. This study was performed in elderly patients over 65 years of age who administered clopidogrel from January 2005 to June 2006 in South Korea. Serious Adverse Events (SAEs) as drug interactions of clopidogrel were defined as any ambulatory hospitalization for ischemic diseases within comcomitant medication period of clopidogrel. Information Component (IC) and Relative Risk (RR) were calculated to compare the proportion of drug-SAE pairs in order to select drug specific SAEs. IC and RR signals of clopidogrel drug interaction were screened when IC's 95% confidence interval was greater than 0 and RR's 95% confidence interval was greater than 1 respectively. All detected signals were compared to references such as $Micromedex^{(R)}$ and 2010 Drug Interaction $Facts^{TM}$. Sensitivity, specificity, positive predicted value and negative predicted value were used to evaluate usefulness of this method. Among 13,252,930 cases of elderly patients who co-administered clopidogrel and other drugs, 47,485 cases were detected as SAE. Of these, one-hundred nine cases were detected by the IC-based data-mining approach and ninety one cases were detected by the RR-based data-mining approach. Total One-hundred sixty three unrecognized signals were detected by IC or RR. Twelve signals from IC-based data-mining (57.1%) were corresponded with drug interactions from references and eight signals from RR-based data-mining (38.1%) were corresponded with drug interactions from references. These signals include proton pump inhibitors, calcium channel blockers and HMG CoA reductase Inhibitors, which were known to affect CYP450 metabolism. Further studies using HIRA claims database are necessary to develop appropriate data-mining measure.