• BMB Reports
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• v.33 no.1
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• pp.54-58
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• 2000

Recent research results regarding the very long chain transmembrane ${\alpha},{\omega}-dicarboxylic$ components in the membrane of extremophilic eubacteria, such as Sarcina ventriculi, Thennotoga maritima, and Thermoanaerobacter ethanolicus have raised interesting questions concerning the physical and biochemical function on these components in the membrane. In order to understand the dynamic characteristics of these acids which reside in the bilayer membrane, 580 ps molecular dynamic simulations at 300 K were performed for two model systems. These systems were the bilayer with regular chain (C16:0 or C18:1) fatty acid methyl esters and the fatty acid bilayer containing very long chain transmembrane dicarboxylic acid methyl esters (${\alpha},{\omega}-15,16-dimethyltriacotane-dioate$ dimethyl ester; C32:0). Our analyses indicate that very long chain transmembrane dicarboxylic acids have a noticeable influence on the bilayer dynamics at a sub-nanosecond time scale. The center-ofmass mean-squared-displacement (MSD) of regular chain fatty acids adjacent to the very long chain transmembrane dicarboxylic acids decreased, the long-axis order parameter increased, and the reorientational motions of methylene groups were slowed along the hydrocarbon chains. These results indicate that the very long chain transmembrane dicarboxylic acids reduce the molecular order of the whole bilayer membrane.

• Korean Journal of Clinical Laboratory Science
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• v.49 no.4
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• pp.495-497
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• 2017

Thalassemia major is a genetic disorder with a defective synthesis of either the alpha or the beta chain of hemoglobin A. Blood transfusion is crucial for the survival in these patients. Unfortunately, endocrine dysfunction is a very common complication in these patients and is principally due to excessive iron overload as a result of frequent blood transfusions. Although regular blood transfusion may increase life expectancy, disturbances in growth and pubertal development, abnormal gonadal functions, impaired thyroid, parathyroid and adrenal functions, diabetes, and disorderly bone growth are common side effects. We hereby present a case of a 23-year-old, unmarried woman with beta thalassemia major presenting with primary amenorrhea, poor development of secondary sexual character, and short stature. Thorough history, clinical examination, and laboratory investigation, including dynamic function test (insulin tolerance test) were conducted. These tests confirmed that she had multiple endocrinopathies, including hypogonadotropic hypogonadism, growth hormone deficiency, and subclinical adrenal insufficiency, which were caused by iron overload. She required hormone replacement therapy. Early recognition of possible deficiencies in hypothalamo-pituitary-end organ hormones caused by iron overload in thalassemia patients that undergo frequent blood transfusion procedures is essential. Appropriate treatments, including transfusion regimen and chelation therapy, as well as specific treatment of each complication are the crucial for the successful management and improvement of quality of life these patients.

• Journal of Dental Rehabilitation and Applied Science
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• v.22 no.3
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• pp.203-210
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• 2006

Although porcelain fused to metal crowns made from non-precious metal have good mechanical properties, they also have disadvantages such as the poor biological acceptability and the low corrosional resistance. Titanium is used as the alternative metal for porcelain fused to metal crowns, in spite of difficulties in casting. For that reason non-precious alloy including titanium which is easy to cast is currently used. This study evaluated the bond strength between non-precious alloy including titanium and Ni-Cr alloy. $Tilite^{(R)}V$ as non-precious alloy including titanium, $Rexilium^{(R)}V$ as Ni-Cr alloy and $Omega900^{(R)}$ and $Vintage(Regular)^{(R)}$ as porcelain powders were used. The results were as follows. 1. In comparison with the kind of alloy, the bond strength of $Tilite^{(R)}V$ was lower than that of $Rexilium^{(R)}V$. There was no significant difference between two groups. 2. In comparison with the kind of porcelain powder, the bond strength of $Omega900^{(R)}$ was higher than that of $Vintage(Regular)^{(R)}$ in $Tilite^{(R)}V$. There was significant difference between two groups(p < 0.05).

• International Journal of Naval Architecture and Ocean Engineering
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• v.9 no.5
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• pp.499-508
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• 2017

This paper uses optimization techniques to obtain bow hull form of a 66,000 DWT bulk carrier in calm water and in waves. Parametric modification functions of SAC and section shape of DLWL are used for hull form variation. Multi-objective functions are applied to minimize the wave-making resistance in calm water and added resistance in regular head wave of ${\lambda}/L=0.5$. WAVIS version 1.3 is used to obtain wave-making resistance. The modified Fujii and Takahashi's formula is applied to obtain the added resistance in short wave. The PSO algorithm is employed for the optimization technique. The resistance and motion characteristics in calm water and regular and irregular head waves of the three hull forms are compared. It has been shown that the optimal brings 13.2% reduction in the wave-making resistance and 13.8% reduction in the added resistance at ${\lambda}/L=0.5$; and the mean added resistance reduces by 9.5% at sea state 5.

• Journal of the Society of Naval Architects of Korea
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• v.42 no.3
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• pp.212-219
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• 2005

Real sea waves in a towing wave basin have been generated using random periodic motion of the segmented wave makers and the wave reflections of sidewalls. Theoretically, the real sea waves can be described by the superposition of many random oblique waves. This paper introduces numerical real sea wave generation in a rectangular wave basin using spectral method that uses a superposition of orthogonal functions which have to satisfy the Laplace equation. Oblique regular waves, long crested irregular waves and real sea waves were simulated and met the requirement of sidewall wave reflection and wave absorption. MLM (Maximum Likelihood Method) and Spatial Fourier Transform were used in order to obtain propagated wave direction characteristics. The estimated results proved the usefulness of the method and the performances showed reasonable directional patterns comparing with generating patterns.

• Journal of the Korean Home Economics Association
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• v.29 no.1
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• pp.27-35
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• 1991

This study was carried out to investigate the influence of the various physiological function caused by brassiere wearing. The four experimental methods used in this study are as follows. For example, the Roentgen photographing, Body measurement by Sliding Gauge, the measurement of the Electrocardiogram and Blood Pressure. The results of the Electrocardiogram and Blood Pressure. The results of the investigation were as follows: 1. In experimental change by Sliding Gauge and Body measurement, The bust point was rised in order AB1>B2. The width of right and left bust point was decreased in order of A>B1>B2. According to, The supplementary effect of brassiere wearing was excellent in B2. 2. In the change of various organs by Roentgen photographing, The width of the chest and size of the heart were decreased in regular order of A>B1>B2. The diaphragm and the others were not showed change. 3. In the experimental result by measurement of the electrocardiogram, The interval of heart palpitation was decreased in order A>B1>B2 and the pulse frequency was similar. 4. In the experimental result by the blood pressure measurement, A had the highest blood pressure and B2 had the lowest pressure in all variables.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.60 no.2
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• pp.252-256
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• 2011

We analyze the channel capacity with considering the effect of the loading conditions of indoor PLC networks on channel state information. We consider various numbers of load for two kinds of the networks with regular length branches and a deployed network of indoor PLC. For calculating the channel capacity degradation, two noise scenarios and impedances are considered. From the simulation results, we suggest the robust regression lines for modeling the channel capacity degradation. In the cases of 0 $\Omega$ and $Z_0$ loads, natural log and linear function curve show the best goodness of fit, respectively. For the deployed indoor PLC network with 0 $\Omega$ loads, compared with the networks with regular length branches, the goodness of fit decreases by the amount of 0.12 and 0.15 for low noise and high noise scenarios, respectively. Using the regression lines, we can estimate the channel capacity degradation without measurement.

• Journal of International Academy of Physical Therapy Research
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• v.10 no.2
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• pp.1756-1762
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• 2019

Background: Functional ankle instability (FAI) indicating a decrease in muscle strength, proprioception, neuromuscular control, balance and postural control function. Objective: To investigate the effect of jumping exercise on the supporting surface on the ankle muscle thickness, proprioceptive sensation, and balance in adults with FAI. Design: Randomized Controlled Trial. Methods: Twenty young people with FAI were randomly assigned to the unstable supporting surface jump group (N=10) and the stable supporting surface jump group (N=10). The intervention was conducted three times a week for eight weeks, and for 30 minutes per session. Trampoline was used as an unstable support surface and the stable support surface was carried out on a regular floor. The thickness of the tibialis anterior muscle and medial gastrocnemius muscle was measured by ultrasonography, and the proprioception of dorsiflexion and plantarflexion was measured using an electrogoniometer. The dynamic balance was also measured with a balance meter. Results: The the muscle thickness of the medial gastrocnemius muscle was significantly higher in the stable supporting surface jump group than in the unstable supporting surface jump group (p<.05). Furthermore, the plantar flexion proprioception and dynamic balance were significantly improved in the unstable supporting surface jump group than in the stable supporting surface jump group in the intergroup comparison (p<.05). Conclusions: The conclusion has been reached in this study that the jumping exercise on the unstable supporting surface could be a more effective in improving FAI than the regular surface.

• Journal of Korean Public Health Nursing
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• v.26 no.2
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• pp.328-340
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• 2012

Purpose: This study explored the degree of internet addiction and its influencing factors in lower grade elementary school children in rural areas. Methods: Subjects included 1,137 elementary school children. A structured questionnaire consisting of questions internet addiction, family function and school life satisfaction was used for data collection. Descriptive statistics, ${\chi}^2$-test, ANOVA and Correlation and Regression were performed using a SPSS program. Results: Among the subjects, 85.8% were regular users, 8.1% were potential risk users, and 6.1% were high-risk users. Career of internet use, daily internet access time, the number of conversations per week, the number of times spent eating out and traveling with parents within the last month and activities with friends, and satisfaction on school life differed significantly according to the degree of internet addiction. Finally, among the factors studied, daily internet access time, conversations within family, activities with friends and school life satisfaction in children in early elementary school was 20.7% of the explanatory power of the subjects' degree of internet addiction, collectively. Conclusion: Use of the internet by early elementary school children should be monitored and strategies to promote familial conversations, activities with peers and school life satisfaction should be developed.

• Journal of Chest Surgery
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• v.21 no.6
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• pp.979-983
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• 1988

Calcium channel blockers may prevent myocardial injury during cardioplegia and reperfusion. This study was done to evaluate the effects of diltiazem cardioplegia on myocardial protection during ischemic arrest and recovery of myocardial function after reperfusion. Four formulations of crystalloid cardioplegic solutions, GIK solution[group I, n=12], diltiazem[lug/ml GIK] in GIK solution[group II, n=7], ],diltiazem[2ug/ml GIK] in GIK solution[group III, n=6] and diltiazem[4ug/ml GIK] in GIK solution[group IV, n=6] were compared in isolated working rat heart subjected to a long period [2 hours] of hypothermic arrest with multi-dose infusion. Diltiazem cardioplegia[group II, III and IV]was found to be superior in nearly all aspects. Diltiazem cardioplegia showed faster recovery of regular rhythm and lower incidence of ventricular fibrillation than group I did. In comparing mechanical function in all experimental hearts, the mean postischemic recoveries of aortic flow, cardiac output, peak aortic pressure, stroke volume and stroke work[expressed as a percentage of its preischemic control] were significantly greater in group II, III and IV[diltiazem cardioplegia] than in group I. The infused amount of cardioplegic solution was more increased by the addition of diltiazem to GI K solution. [p < 0.01] Creatine kinase leakage tended to be lower in hearts receiving diltiazem cardioplegia, especially in group III and IV[p<0.05] than in those receiving GIK solution only[group I]. Diltiazem cardioplegia results in the increased flow of cardioplegic solution and the decreased ischemic injury of myocardium during ischemic arrest and the improved recovery of myocardial function after reperfusion, and a dose-response relation must be established before clinical use.