• Title/Summary/Keyword: regional segmentation

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Cortical Iron Accumulation as an Imaging Marker for Neurodegeneration in Clinical Cognitive Impairment Spectrum: A Quantitative Susceptibility Mapping Study

  • Hyeong Woo Kim;Subin Lee;Jin Ho Yang;Yeonsil Moon;Jongho Lee;Won-Jin Moon
    • Korean Journal of Radiology
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    • v.24 no.11
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    • pp.1131-1141
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    • 2023
  • Objective: Cortical iron deposition has recently been shown to occur in Alzheimer's disease (AD). In this study, we aimed to evaluate how cortical gray matter iron, measured using quantitative susceptibility mapping (QSM), differs in the clinical cognitive impairment spectrum. Materials and Methods: This retrospective study evaluated 73 participants (mean age ± standard deviation, 66.7 ± 7.6 years; 52 females and 21 males) with normal cognition (NC), 158 patients with mild cognitive impairment (MCI), and 48 patients with AD dementia. The participants underwent brain magnetic resonance imaging using a three-dimensional multi-dynamic multi-echo sequence on a 3-T scanner. We employed a deep neural network (QSMnet+) and used automatic segmentation software based on FreeSurfer v6.0 to extract anatomical labels and volumes of interest in the cortex. We used analysis of covariance to investigate the differences in susceptibility among the clinical diagnostic groups in each brain region. Multivariable linear regression analysis was performed to study the association between susceptibility values and cognitive scores including the Mini-Mental State Examination (MMSE). Results: Among the three groups, the frontal (P < 0.001), temporal (P = 0.004), parietal (P = 0.001), occipital (P < 0.001), and cingulate cortices (P < 0.001) showed a higher mean susceptibility in patients with MCI and AD than in NC subjects. In the combined MCI and AD group, the mean susceptibility in the cingulate cortex (β = -216.21, P = 0.019) and insular cortex (β = -276.65, P = 0.001) were significant independent predictors of MMSE scores after correcting for age, sex, education, regional volume, and APOE4 carrier status. Conclusion: Iron deposition in the cortex, as measured by QSMnet+, was higher in patients with AD and MCI than in NC participants. Iron deposition in the cingulate and insular cortices may be an early imaging marker of cognitive impairment related neurodegeneration.

A Study on Object-Based Image Analysis Methods for Land Cover Classification in Agricultural Areas (농촌지역 토지피복분류를 위한 객체기반 영상분석기법 연구)

  • Kim, Hyun-Ok;Yeom, Jong-Min
    • Journal of the Korean Association of Geographic Information Studies
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    • v.15 no.4
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    • pp.26-41
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    • 2012
  • It is necessary to manage, forecast and prepare agricultural production based on accurate and up-to-date information in order to cope with the climate change and its impacts such as global warming, floods and droughts. This study examined the applicability as well as challenges of the object-based image analysis method for developing a land cover image classification algorithm, which can support the fast thematic mapping of wide agricultural areas on a regional scale. In order to test the applicability of RapidEye's multi-temporal spectral information for differentiating agricultural land cover types, the integration of other GIS data was minimized. Under this circumstance, the land cover classification accuracy at the study area of Kimje ($1300km^2$) was 80.3%. The geometric resolution of RapidEye, 6.5m showed the possibility to derive the spatial features of agricultural land use generally cultivated on a small scale in Korea. The object-based image analysis method can realize the expert knowledge in various ways during the classification process, so that the application of spectral image information can be optimized. An additional advantage is that the already developed classification algorithm can be stored, edited with variables in detail with regard to analytical purpose, and may be applied to other images as well as other regions. However, the segmentation process, which is fundamental for the object-based image classification, often cannot be explained quantitatively. Therefore, it is necessary to draw the best results based on expert's empirical and scientific knowledge.

Regional Analysis of Unemployment Hazard Rate and the Influencing Factors on It (지역별 실업탈출확률 및 요인에 관한 연구)

  • Jeong, Insoo
    • Journal of Labour Economics
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    • v.26 no.1
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    • pp.111-151
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    • 2003
  • This study attempted to analize the hazard rate from unemployment and the influncing factors on the rate by regions. The data this study uses is Korea Labor Institute Panal Study(1998-2001) and the models are hazard analysis and Cox model. The results of hazard analysis are as follow. In capital and it's vicinity, the duration of unemployment is shorter than other regions even if the unemployment rate is higher. The labor market segmentation is confirmed between capital and it's vicinity region and other regions. Kyungsang region is higher in the unemployment hazard rate than Chunla or Chungchung regions. The duration of unemployment in capital and it's vicinity is 9.29 months comparing 11.86 months in the other region. The difference is statistically significant by the significance level 0.001. The duration of unemployment in Kyungsang is 6.96 months comparing 10.95 months in Chunla region. The Cox results which indicate the influncing factors on the hazard rate are as follow. In the regions like non-metro cities and non-capital and vicinitiy, the factors such as female, tenure, wage earners, manufacturing, wholesale and retale decrease the hazard rate. The results indicate that active labor market policies region by region are needed in Korea, especially for the marginal unemployed workes from non flourishing sectors.

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Partial Path Selection Method in Each Subregion for Routing Path Optimization in SEF Based Sensor Networks (통계적 여과 기법 기반 센서 네트워크에서 라우팅 경로 최적화를 위한 영역별 부분 경로 선택 방법)

  • Park, Hyuk;Cho, Tae-Ho
    • Journal of the Korean Institute of Intelligent Systems
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    • v.22 no.1
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    • pp.108-113
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    • 2012
  • Routing paths are mightily important for the network security in WSNs. To maintain such routing paths, sustained path re-selection and path management are needed. Region segmentation based path selection method (RSPSM) provides a path selection method that a sensor network is divided into several subregions, so that the regional path selection and path management are available. Therefore, RSPSM can reduce energy consumption when the path re-selection process is executed. However, it is hard to guarantee optimized secure routing path at all times since the information using the path re-selection process is limited in scope. In this paper, we propose partial path selection method in each subregion using preselected partial paths made by RSPSM for routing path optimization in SEF based sensor networks. In the proposed method, the base station collects the information of the all partial paths from every subregion and then, evaluates all the candidates that can be the optimized routing path for each node using a evaluation function. After the evaluation process is done, the result is sent to each super DN using the global routing path information (GPI) message. Thus, each super DN provides the optimized secure routing paths using the GPI. We show the effectiveness of the proposed method via the simulation results. We expect that our method can be useful for the improvement of RSPSM.

GIS-based Market Analysis and Sales Management System : The Case of a Telecommunication Company (시장분석 및 영업관리 역량 강화를 위한 통신사의 GIS 적용 사례)

  • Chang, Nam-Sik
    • Journal of Intelligence and Information Systems
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    • v.17 no.2
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    • pp.61-75
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    • 2011
  • A Geographic Information System(GIS) is a system that captures, stores, analyzes, manages and presents data with reference to geographic location data. In the later 1990s and earlier 2000s it was limitedly used in government sectors such as public utility management, urban planning, landscape architecture, and environmental contamination control. However, a growing number of open-source packages running on a range of operating systems enabled many private enterprises to explore the concept of viewing GIS-based sales and customer data over their own computer monitors. K telecommunication company has dominated the Korean telecommunication market by providing diverse services, such as high-speed internet, PSTN(Public Switched Telephone Network), VOLP (Voice Over Internet Protocol), and IPTV(Internet Protocol Television). Even though the telecommunication market in Korea is huge, the competition between major services providers is growing more fierce than ever before. Service providers struggled to acquire as many new customers as possible, attempted to cross sell more products to their regular customers, and made more efforts on retaining the best customers by offering unprecedented benefits. Most service providers including K telecommunication company tried to adopt the concept of customer relationship management(CRM), and analyze customer's demographic and transactional data statistically in order to understand their customer's behavior. However, managing customer information has still remained at the basic level, and the quality and the quantity of customer data were not enough not only to understand the customers but also to design a strategy for marketing and sales. For example, the currently used 3,074 legal regional divisions, which are originally defined by the government, were too broad to calculate sub-regional customer's service subscription and cancellation ratio. Additional external data such as house size, house price, and household demographics are also needed to measure sales potential. Furthermore, making tables and reports were time consuming and they were insufficient to make a clear judgment about the market situation. In 2009, this company needed a dramatic shift in the way marketing and sales activities, and finally developed a dedicated GIS_based market analysis and sales management system. This system made huge improvement in the efficiency with which the company was able to manage and organize all customer and sales related information, and access to those information easily and visually. After the GIS information system was developed, and applied to marketing and sales activities at the corporate level, the company was reported to increase sales and market share substantially. This was due to the fact that by analyzing past market and sales initiatives, creating sales potential, and targeting key markets, the system could make suggestions and enable the company to focus its resources on the demographics most likely to respond to the promotion. This paper reviews subjective and unclear marketing and sales activities that K telecommunication company operated, and introduces the whole process of developing the GIS information system. The process consists of the following 5 modules : (1) Customer profile cleansing and standardization, (2) Internal/External DB enrichment, (3) Segmentation of 3,074 legal regions into 46,590 sub_regions called blocks, (4) GIS data mart design, and (5) GIS system construction. The objective of this case study is to emphasize the need of GIS system and how it works in the private enterprises by reviewing the development process of the K company's market analysis and sales management system. We hope that this paper suggest valuable guideline to companies that consider introducing or constructing a GIS information system.

The Determinants of Digital Trust of Senior Consumers in the Era of Digital Transformation (디지털 트랜스포메이션 시대, 시니어 소비자의 디지털 소비여건 신뢰 형성 요인 연구)

  • Mina Jun;Miyea Kim;Jeongsoo Han
    • Knowledge Management Research
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    • v.23 no.4
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    • pp.91-112
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    • 2022
  • In order to improve the quality of consumption in senior generation, it is necessary to build trust in the digital consumption environment. However, there are limitations from previous researches on consumption in the digital environment that has mainly focused on Millennial and Z generations. Therefore, this study aims to examine the antecedents of digital consumption trust and to explore the market segments of senior generation created by the dynamics of these antecedents. In addition, in order to provide practical implications, we investigate the difference in the level of perceived digital consumption trust using segmentation. This study, therefore, used 2021 Korea's consumer life index data conducted by the Korea Consumer Agency for general consumers, and only consumer data of 60s and older are extracted for the analysis. As a result, we confirm from the main results that the three antecedents, consumer competency, perceived corporate responsibility, and local community's problem-solving environment, are significant in building the digital consumption trust in the senior generation. It is academically significant in this aspect to look at approaches to improve senior customers' trust in digital consumption circumstances by dividing generations because generations exhibit varying levels of understanding of online consumption or digital consumption conditions. It is academically significant in this aspect to look at approaches to improve senior customers' trust in digital consumption circumstances by dividing generations because generations exhibit varying levels of understanding of online consumption or digital consumption conditions. Additionally, it is proposed as a practical implication that it should be managed so that significant improvements of customers, businesses, and regional public institutions are developed in order to allow the senior consumers to prepare trusted digital consumption circumstances.