• Journal of the Korean Regional Science Association
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• v.40 no.2
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• pp.39-55
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• 2024

This study attempted to derive a plan for sustainable operate by identifying the status and operation condition of the community facilities of the Youth Jochiwon Project through case studies and interviews. Examining at the status and operation condition, 13 facilities are scheduled to be built in Jochiwon by 2025, but many facilities have not yet been prepared for specific operation plans. Second, the possibility of sustainable operation is positively evaluated based on creating jobs and profits through connection with other facilities and the introduction of paid system. Third, administrative support is being provided in various aspects, but there was a regret due to the limitation of the budget. It is expected that the function of health/welfare and leisure/culture can be strengthened for sustainable operation, support in term of administrative support is needed, and support and management function can be strengthened by utilizing the urban registration support center.

• Journal of the Korean Institute of Rural Architecture
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• v.20 no.3
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• pp.19-26
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• 2018

There are still a number of "olles" existing with traditional alley characteristics in the inner city of Jeju. As a matter of fact, the renovation of old buildings and the protection of alley space are facing a dilemma due to the existence of less than 4m-width-roads in the area of "Mu-geun-sung". This study examines the current status of alley space in "Mu-geun-sung" area; and puts forward to the potential possibility and limitation of alley space regeneration via exploring the applicable scheme of building agreement. In the field survey, a number of regions in inner city of Jeju witnesses the existing majority of invaluable, conventional olles. So as to grasp the feasibility in "Mu-geun-sung" area, we designs a simulating experiment to carry out the Building Agreement; and compares with the current development model in this area. Building Agreement implies to establish gradually a separation of land ownership under the existing unified development of landowners and users, thus to explore a variety of land exploitation systems by separating land ownership and right to use land. As a result, the deterioration of the street landscape results from the increase of building storey numbers. The damages to the surrounding environment brought by the newly built buildings will be minimized as well as keeping the maximum building volume rate. Obviously, these measures will alleviate infringement to the traditional residential sunlight and privacy space effectively, and reduce the pressure from high-rise buildings to the alley space, so that the landscape of the alley will enhance to form a more comfortable alley environment.

• Korean Journal of Plant Resources
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• v.33 no.5
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• pp.536-549
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• 2020

Soybean (Glycine max (L.) Merrill) is one of the most important crops of the world. With the completion of the soybean genome sequence, the Korean soybean core collection consisted of 430 accessions with genetic and phenotypic diversity was constructed in recent year. The availability of genome sequences and core collection will result in the crop improvement by molecular breeding using the various accessions and genome editing approaches. Efficient tissue culture techniques, such as haploid production, protoplast culture and plant regeneration from various organs are essential for the successful molecular biological approach and crop improvement. However, soybean is still considered to be recalcitrant in tissue culture because of the low frequency of regeneration and limitation of available responsive cultivars. In this study, we discuss the recent studies of tissue culture technology and methodology for efficient tissue culture to genetic improvement and application of molecular biotechnology in soybean.

• Journal of Periodontal and Implant Science
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• v.50 no.6
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• pp.379-391
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• 2020

Purpose: The aims of this study were to evaluate the 5-year cumulative survival rate (CSR) of implants placed with guided bone regeneration (GBR) compared to implants placed in native bone, and to identify factors contributing to implant failure in regenerated bone. Methods: This retrospective cohort study included 240 patients who had implant placement either with a GBR procedure (regenerated bone group) or with pristine bone (native bone group). Data on demographic features (age, sex, smoking, and medical history), location of the implant, implant-specific features, and grafting procedures and materials were collected. The 5-year CSRs in both groups were estimated using Kaplan-Meier analysis. Risk factors for implant failure were analyzed with a Cox proportional hazards model. Results: In total, 264 implants in the native bone group and 133 implants in the regenerated bone group were analyzed. The 5-year CSRs were 96.4% in the regenerated bone group and 97.5% in the native bone group, which was not a significant difference. The multivariable analysis confirmed that bone status was not an independent risk factor for implant failure. However, smoking significantly increased the failure rate (hazard ratio, 10.7; P=0.002). Conclusions: The 5-year CSR of implants placed in regenerated bone using GBR was comparable to that of implants placed in native bone. Smoking significantly increased the risk of implant failure in both groups.

• The Journal of the Korea Contents Association
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• v.20 no.4
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• pp.181-188
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• 2020

Many areas are on the verge of disappearing soon due to low birth rates and an increasing number of elderly people. To overcome this crisis, efforts must be made to escape the destruction of the area through the village community. This study was conducted to find out the use of online platforms for village communities and through literature research, current status surveys, and surveys, we wanted to find out how online platforms are being utilized. The study results are summarized as follows. First, urban renewal support projects are currently being conducted under the government-led initiative to revitalize the village community, and online platforms are being used mainly by local governments' urban renewal support centers. Second, if you look at the frequency of online platform usage by ordinary people, you are using Naver the most in all age groups, and next, you are using the website. People in their 20s and 30s use Instagram more than Facebook, while those in their 40s and 50s use Facebook more than Instagram. In utilizing the online platform for the village community, the status and frequency of use of the online platform should be taken into account comprehensively.

• Journal of Periodontal and Implant Science
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• v.48 no.2
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• pp.92-102
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• 2018

Purpose: This study investigated the validity of the Charlson comorbidity index (CCI) as a predictor of periodontal disease (PD) over a 12-year period. Methods: Nationwide representative samples of 149,785 adults aged ${\geq}60$ years with PD (International Classification of Disease, 10th revision [ICD-10], K052-K056) were derived from the National Health Insurance Service-Elderly Cohort during 2002-2013. The degree of comorbidity was measured using the CCI (grade 0-6), including 17 diseases weighted on the basis of their association with mortality, and data were analyzed using multivariate Cox proportional-hazards regression in order to investigate the associations of comorbid diseases (CDs) with PD. Results: The multivariate Cox regression analysis with adjustment for sociodemographic factors (sex, age, household income, insurance status, residence area, and health status) and CDs (acute myocardial infarction, congestive heart failure, peripheral vascular disease, cerebral vascular accident, dementia, pulmonary disease, connective tissue disorders, peptic ulcer, liver disease, diabetes, diabetes complications, paraplegia, renal disease, cancer, metastatic cancer, severe liver disease, and human immunodeficiency virus [HIV]) showed that the CCI in elderly comorbid participants was significantly and positively correlated with the presence of PD (grade 1: hazard ratio [HR], 1.11; P<0.001; grade ${\geq}2$: HR, 1.12, P<0.001). Conclusions: We demonstrated that a higher CCI was a significant predictor of greater risk for PD in the South Korean elderly population.

• Journal of Korean society of Dental Hygiene
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• v.12 no.4
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• pp.759-770
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• 2012

Objectives : The purpose of this study was to examine the awareness of implant wearers about periodontal diseases and implant management, which were closely linked to implant durability, in an effort to obtain information on the right directions for oral health education related to implant self-care and specialized care. Methods : The subjects in this study were 217 patients who wore implant and visited 14 different dental hospitals and clinics in the metropolitan area. After a questioaire survey was conducted and collected data were analyed by the statistical package SPSS 18.0. Results : As for the awareness of the subjects on the regeneration of alveolar ridge by general characteristics, there were statistically significant intergroup gaps according to the number of possessed implant, implant satisfaction and subjective gingival health status(p<0.05). Regarding their awareness of implant durability by general characteristics, there were statistically significant gaps according to the number of possessed implant and oral health education experience(p<0.05). Concerning their awareness of the cycle of regular implant checkup by general characteristics, there were statistically significant gaps according to occupation, subjective gingival health status and oral health education experience(p<0.05). Conclusions : The above-mentioned findings suggest that in order to ensure the long-term safe maintenance of implant, the way of looking at periodontal diseases and implant management should be changed. Specifically, more intensive oral health education should be provided for implant wearers to be aware of the importance of self-care and specialized care to change their oral health behavior, and clinical dental hygienists should improve their role performance to make it happen.

• Journal of the Architectural Institute of Korea Planning & Design
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• v.34 no.9
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• pp.31-42
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• 2018

With the rapid progress of urbanization today, communities among members of society have collapsed. For dealing with the collapse of communities, special laws regarding urban regeneration revitalization and support were enforced and each local government founded community centers to revitalize urban village communities. These community centers were built to play a pivotal role in communities, but they have difficulties managing and supervising. Therefore, this study aims to provide basic data for community center planning and revitalization by examining and analyzing the present state of community center spaces for creation of communities among residents and the present state of use so the existing purpose of establishment as a base space of village community revitalization can be achieved in the future. For this study, first, in the literature review, the concepts of village community and community center were established, based on a theoretical consideration, and the need of research was identified through consideration of preceding studies. Second, in relation to the present state of use, the present state of community center spaces, programs, management and supervision, locations and populations was investigated and analyzed, and community center users' basic characteristics, satisfaction and consciousness of community centers were examined and analyzed. Based on this method and analysis, this study is focused on providing basic data for community center revitalization and planning.

• Proceedings of the Botanical Society of Korea Conference
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• 1995.06a
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• pp.40-56
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• 1995

During the past two decades, China has seen her great progress in plant biotechnology. Since the Chinese market of herb medicine is huge, while the plant resources are shrinking, particular emphasis has been placed in plant tissue and cell cultures of medicinal plants, this includes fast propagation, protoplast isolation and regeneration, cell suspension cultures and large scale fermentation. To optimize culture conditions for producing secondary compounds in vitro, various media, additives and elicitors have been tested. Successful examples of large scale culture for the secondary metabolite biosynthesis are quite limited : Lithospermum ery throrhizon and Arnebia euchroma for shikonin derivatives, Panax ginseng, P. notoginseng, P. quinquefolium for saponins, and a few other medicinal plants. Recent development of genetic transformation systems of plant cells offered a new approach to in vitro production of secondary compounds. Hairy root induction and cultures, by using Ri-plasmid, have been reported from a number of medicinal plant species, such as Artemisia annua that produces little artemisinin in normal cultured cells, and from Glycyrrhiza uralensis. In the coming five years, Chinese scientists will continue their work on large scale cell cultures of a few of selected plant species, including Taxus spp. and A. annua, for the production of secondary metabolites with medicinal interests, one or two groups of scientists will be engaged in molecular cloning of the key enzymes in plant secondary metabolism.

• Journal of Biomedical Engineering Research
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• v.31 no.2
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• pp.87-93
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• 2010

Researches for stem cells have been focused on scientists in biomedical sciences as well as clinical application for its great therapeutic potentials. Stem cells have two distinct characteristics: self-renewal and differentiation. In this short review, the links between stem cell research and biomedical engineering is discussed based on the basic characteristics of stem cells. This concept can be extended to the fundamental questions of biological sciences for cells such as proliferation, apoptosis, differentiation, and migration. For understanding proliferation and apoptosis of stem cells, techniques from biomedical engineering such as surface patterning, MEMS, nanotechnologies have been used. The advanced technologies such as microfluidic technologies, three dimensional scaffold fabrication, and mechanical/electrical stimulation have also been used in cell differentiation and migration. Basic and unsolved questions in the stem cell research field have limitations by studying conventional technologies. Therefore, the strategic fusion between stem cell biology and novel biomedical engineering field will break the barriers for understanding fundamental questions of stem cells, which can open the window for the clinical applications of stem cell based therapeutics as well as regeneration of damaged tissues.