• Title/Summary/Keyword: regeneration failure

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The Survey Study on the User Satisfaction of Roppongi Hills in Japan (일본 록본기 힐즈의 이용자 만족도에 관한 조사 연구)

  • Lee, Seong-Ryeong;Woo, Jae-Dong;Kang, Boo-Seong
    • Proceeding of Spring/Autumn Annual Conference of KHA
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    • 2008.11a
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    • pp.442-447
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    • 2008
  • With the advances in the high-tech knowledge and service industries, along with a high-flying economy, the industrial structures of many cities have changed. The subject of the successful cases of dimensional integrated complexes in Roppongi Hills, the actions and preferences of these complexes'users were surveyed and analyzed in this study to determine the factors that contribute to the success or failure of such development projects. The results of the survey that was conducted in this study regarding the satisfaction of the residents of Roppongi Hills with such complexes will be considered in the formulation of a construction plan and will be used as base data for designing a large-scale dimensional integrated complex in Korea.

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A Study on Effect of Applying Energy Storage System on SeoulMetro Line 2 (에너지저장시스템의 서울메트로 2호선 적용 효과에 관한 연구)

  • An, Cheon-Heon;Lee, Han-Min;Kim, Gil-Dong;Lee, Hi-Sung
    • Proceedings of the KSR Conference
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    • 2009.05a
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    • pp.966-971
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    • 2009
  • The recent environmental protection trend requires more strict energy saving, therefore every transportation system should reduce energy consumption to the minimum value. High-efficiency operation system, energy saving and CO2 emissions shall be addressed as important issue in railway system. These issues are the most essential factors of railway, compared to major public transportation system. Recently, saving energy in the electric railway system has been studied. For such new energy saving, the Energy storage system is considered for saving energy. Energy saving is possible by efficient use of regenerated energy. Regenerated energy is recycled amongst vehicles by mean of charge and discharge corresponding to powering and braking of electric vehicle operations. This energy saving contributes to cut CO2 to reduce greenhouse gas emissions. Recycling regenerated energy demonstrate significant effect on peak cut of consumption energy in railway substation. Absorption of excess energy avoids regeneration failure due to high traction voltage. This paper presents effects by applying the energy storage system to SeoulMetro Line 2.

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A Study on the Properties of Porous Concrete For Kelp Forest Regeneration Using Cement Coating Granular Fertilizer (시멘트 코팅 입상비료를 이용한 조장조성용 포러스콘크리트의 특성에 관한 연구)

  • Park Seong Bum;Lee Jun;Kim Jeong Hwan;Seo Dae Seuk;Lee Byung Jae;Song Jae Lib
    • Proceedings of the Korea Concrete Institute Conference
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    • 2005.05b
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    • pp.489-492
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    • 2005
  • The Purpose of this study is to develope the method for early recovery of the biodiversity in the oligotrophical costal area. The result of this study, the dissolution ratio is superior in the case which the cement coating thickness of the granular fertilizer is below 1mm. From the failure-side it is judged with the fact that appropriate to use the separate charging method and vibration compaction method. For the cases of the mixing ratio of cement coating granular fertilizer, there was not any clear tendency for the change of the strength up to 20$\%$ of the mixing ratio. However, at the 30$\%$ mixing ratio, decrease of the strength was noticed. So it can be concluded that the stability can be achieved in the range of 20$\%$ and below.

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Design Parameters of Polymers for Tissue Engineering Applications

  • Lee, Kuen-Yong
    • Macromolecular Research
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    • v.13 no.4
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    • pp.277-284
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    • 2005
  • The loss or failure of an organ or tissue can occur because of accident or disease, for which tissue or organ transplantation is a generally accepted treatment. However, this approach is extremely limited due to donor shortage. Tissue engineering is a new and exciting strategy, in which patients who need a new organ or tissue are supplied with a synthetic organ or tissue. In this approach, tissues are engineered using a combination of the patient's own cells and a polymer scaffold. The polymer scaffold potentially mimics many roles of extracellular matrices in the body. Various polymers have been studied and utilized to date in tissue engineering approaches. However, no single polymer has been considered ideal for all types of tissues and approaches. This paper discusses the design parameters of those polymers potentially useful in tissue regeneration.

CLINICAL STUDY ON THE IMMEDIATE IMPLANTATION WITH GTR THERAPY, INCLUDING BONE HEALING OF EXTRACTION SOCKETS (유도조직재생술에 의한 발치창의 골치유 및 즉시 임프란트 매식에 대한 임상적 연구)

  • Park, Kwang-Ho
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.18 no.2
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    • pp.224-235
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    • 1996
  • Early implantation before sufficient ossification has taken place usually results in osseointegartion failure due to reduced bone-fixture interface area. However, various studies have shown successful osseointegration results following immediate implants concurrently with GTR. The clinical trends have been to shorten the patients' edentulous state by immediate implantation, and reduce the alveolar bone resorption. However, it may be difficult to attain the complete soft tissue coverage of the sites, increasing the chance of infection. Furthermore, there may be more studies needed on the clinical behaviors of e-PTFE membranes, various modofications in the membrane materials and bone graft materials. Various animal and clinical studies have been reported on the successful osseointagration following immediate implantation, but the long-term follow-up studies are limited. The present study investigated 16 immediately-implanted implants with GTR therapy with or without calcium carbonate grafting on 11 patients 3 years after installation and 24-30 months after functional loading. Based on the clinical, radiographic and histologic findings, the following results have been attained. 1. Clinically, stability has been shown on all 16 implants throughout the investigated periods. 2. Radiologically, the alveolar bone loss has progressed up to the polished neck portion but not beyond it, suggesting the progressive osseointegration from the GTR therapy. 3. The GTR method used in the present study is easy to use clinically, and may be appied in the regeneration of ossoeous defects around implants and in the immediate implantation. 4. The difficulty in complete tissue coverage may be avoided by delaying the installation for 2 to 3 weeks after the extraction allowing certain degree of soft tissue healing.

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Mechanical and biological complication rates of the modified lateral-screw-retained implant prosthesis in the posterior region: an alternative to the conventional Implant prosthetic system

  • Lee, Jae-Hong;Lee, Jong-Bin;Kim, Man-Yong;Yoon, Joon-Ho;Choi, Seong-Ho;Kim, Young-Taek
    • The Journal of Advanced Prosthodontics
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    • v.8 no.2
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    • pp.150-157
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    • 2016
  • PURPOSE. The modified lateral-screw-retained implant prosthesis (LSP) is designed to combine the advantages of screw- and cement-retained implant prostheses. This retrospective study evaluated the mechanical and biological complication rates of implant-supported single crowns (ISSCs) inserted with the modified LSP in the posterior region, and determined how these complication rates are affected by clinical factors. MATERIALS AND METHODS. Mechanical complications (i.e., lateral screw loosening [LSL], abutment screw loosening, lateral screw fracture, and ceramic fracture) and biological complications (i.e., peri-implant mucositis [PM] and peri-implantitis) were identified from the patients' treatment records, clinical photographs, periapical radiographs, panoramic radiographs, and clinical indices. The correlations between complication rates and the following clinical factors were determined: gender, age, position in the jaw, placement location, functional duration, clinical crown-to-implant length ratio, crown height space, and the use of a submerged or nonsubmerged placement procedure. RESULTS. Mechanical and biological complications were present in 25 of 73 ISSCs with the modified LSP. LSL (n=11) and PM (n=11) were the most common complications. The incidence of mechanical complications was significantly related to gender (P=.018). The other clinical factors were not significantly associated with mechanical and biological complication rates. CONCLUSION. Within the limitations of this study, the incidence of mechanical and biological complications in the posterior region was similar for both modified LSP and conventional implant prosthetic systems. In addition, the modified LSP is amenable to maintenance care, which facilitates the prevention and treatment of mechanical and biological complications.

Clinical Effect of Guide Bone Regeneration of Mandibular Nonunion in a Geriatric Dog (노령견의 하악골절 불유합 1례에서 골유도재생술의 임상적 효과)

  • Kim, Se-Eun;Shim, Kyung-Mi;Bae, Chun-Sik;Choi, Seok-Hwa;Jeong, Soon-Jeong;Kang, Seong-Soo
    • Journal of Veterinary Clinics
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    • v.30 no.2
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    • pp.127-130
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    • 2013
  • A 13-year-old, 4.2 kg female poodle was referred for failure of first bilateral mandibular surgery at a local animal hospital after pathologic fracture. Surgery was performed with 2.0-mm miniplates/screws and porcine cancellous bone grafts. In addition, because of the large size of the right segmental defect, a barrier absorbable membrane was employed for guide bone regeneration on right mandible. After surgery, follow-ups performed at 1 day, 1, 4, 8, and 12 weeks; there were no signs of dental malocclusion, nonunion or soft tissue infection. However, a 1-year long-term follow-up showed nonunion in the left mandibular fracture site for which a collagen membrane had not been used. It is considered that use of porcine bone graft with barrier absorbable membrane may be effective for the repair of mandibular nonunion in a geriatric dog.

Chitosan/hydroxyapatite composite coatings on porous Ti6Al4V titanium implants: in vitro and in vivo studies

  • Zhang, Ting;Zhang, Xinwei;Mao, Mengyun;Li, Jiayi;Wei, Ting;Sun, Huiqiang
    • Journal of Periodontal and Implant Science
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    • v.50 no.6
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    • pp.392-405
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    • 2020
  • Purpose: Titanium implants are widely used in the treatment of dentition defects; however, due to problems such as osseointegration failure, peri-implant bone resorption, and periimplant inflammation, their application is subject to certain restrictions. The surface modification of titanium implants can improve the implant success rate and meet the needs of clinical applications. The goal of this study was to evaluate the effect of the use of porous titanium with a chitosan/hydroxyapatite coating on osseointegration. Methods: Titanium implants with a dense core and a porous outer structure were prepared using a computer-aided design model and selective laser sintering technology, with a fabricated chitosan/hydroxyapatite composite coating on their surfaces. In vivo and in vitro experiments were used to assess osteogenesis. Results: The quasi-elastic gradient and compressive strength of porous titanium implants were observed to decrease as the porosity increased. The in vitro experiments demonstrated that, the porous titanium implants had no biological toxicity; additionally, the porous structure was shown to be superior to dense titanium with regard to facilitating the adhesion and proliferation of osteoblast-like MC3T3-E1 cells. The in vivo experimental results also showed that the porous structure was beneficial, as bone tissue could grow into the pores, thereby exhibiting good osseointegration. Conclusions: Porous titanium with a chitosan/hydroxyapatite coating promoted MC3T3-E1 cell proliferation and differentiation, and also improved osseointegration in vitro. This study has meaningful implications for research into ways of improving the surface structures of implants and promoting implant osseointegration.

Soft and Hard Tissue Augmentation with/without Polydeoxyribonucleotide for Horizontal Ridge Deficiency: A Pilot Study in a Dog Model

  • Hyunwoo Lim;Yeek Herr;Jong-Hyuk Chung;Seung-Yun Shin;Seung-Il Shin;Ji-Youn Hong;Hyun-Chang Lim
    • Journal of Korean Dental Science
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    • v.17 no.2
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    • pp.53-63
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    • 2024
  • Purpose: To investigate the effects of simultaneous soft and hard tissue augmentation and the addition of polydeoxyribonucleotide (PDRN) on regenerative outcomes. Materials and Methods: In five mongrel dogs, chronic ridge defects were established in both mandibles. Six implants were placed in the mandible, producing buccal dehiscence defects. The implants were randomly allocated to one of the following groups: 1) control: no treatment; 2) GBR: guided bone regeneration (GBR) only; 3) GBR/PDRN: GBR+PDRN application to bone substitute particles; 4) GBR/CTG: GBR+connective tissue grafting (CTG); 5) GBR/VCMX: GBR+soft tissue augmentation using volume stable collagen matrix (VCMX); and 6) group GBR/VCMX/PDRN: GBR+VCMX soaked with PDRN. The healing abutments were connected to the implants to provide additional room for tissue regeneration. Submerged healing was achieved. The animals were euthanized after four months. Histological and histomorphometric analyses were then performed. Results: Healing abutments were gradually exposed during the healing period. Histologically, minimal new bone formation was observed in the dehiscence defects. No specific differences were found between the groups regarding collagen fiber orientation and density in the augmented area. No traces of CTG or VCMX were detected. Histomorphometrically, the mean tissue thickness was greater in the control group than in the other groups above the implant shoulder (IS). Below the IS level, the CTG and PDRN groups exhibited more favorable tissue thickness than the other groups. Conclusion: Failure of submerged healing after tissue augmentation deteriorated the tissue contour. PDRN appears to have a positive effect on soft tissues.