Background: Experience of lung cancer includes negative impacts on both physical and psychological health. Pain is one of the negative experiences of lung cancer. Cognitive behavioral therapy techniques are often recommended as treatments for lung cancer pain. The objective of this review was to synthesize the evidence on the effectiveness of cognitive behavioral therapy techniques in treating lung cancer pain. This review considered studies that included lung cancer patients who were required to 1) be at least 18 years old; 2) speak and read English or Thai; 3) have a life expectancy of at least two months; 4) experience daily cancer pain requiring an opioid medication; 5) have a positive response to opioid medication; 6) have "average or usual" pain between 4 and 7 on a scale of 0-10 for the day before the clinic visit or for a typical day; and 7) able to participate in a pain evaluation and treatment program. This review considered studies to examine interventions for use in treatment of pain in lung cancer patients, including: biofeedback, cognitive/attentional distraction, imagery, hypnosis, and meditation. Any randomized controlled trials (RCTs) that examined cognitive behavioral therapy techniques for pain specifically in lung cancer patients were included. In the absence of RCTs, quasi-experimental designs were reviewed for possible conclusion in a narrative summary. Outcome measures were pain intensity before and after cognitive behavioural therapy techniques. The search strategy aimed to find both published and unpublished literature. A three-step search was utilised by using identified keywords and text term. An initial limited search of MEDLINE and CINAHL was undertaken followed by analysis of the text words contained in the title and abstract, and of the index terms used to describe the article. A second search using all the identified keywords and index terms was then undertaken across all included databases. Thirdly, the reference list of all identified reports and articles were searched for additional studies. Searches were conducted during January 1991- March 2014 limited to English and Thai languages with no date restriction. Materials and Methods: All studies that met the inclusion criteria were assessed for methodological quality by three reviewers using a standardized critical appraisal tool from the Joanna Briggs Institute (JBI). Three reviewers extracted data independently, using a standardized data extraction tool from the Joanna Briggs Institute (JBI). Ideally for quantitative data meta-analysis was to be conducted where all results were subject to double data entry. Odds ratios (for categorical data) and weighted mean differences (for continuous data) and their 95% confidence intervals were to be calculated for analysis and heterogeneity was to be assessed using the standard Chi-square. Where statistical pooling was not possible the finding were be presented in narrative form. Results: There were no studies located that met the inclusion requirements of this review. There were also no text and opinion pieces that were specific to cognitive behavioral therapy techniques pain and lung cancer patients.Conclusions: There is currently no evidence available to determine the effectiveness of cognitive behavioural therapy techniques for pain in lung cancer patients.
Background: To compare the KKU-model rectal tube (KKU-tube) and the conventional rectal tube (CRT) for checking rectal doses during high-dose-rate intracavitary brachytherapy (HDR-ICBT) of cervical cancer. Materials and Methods: Between February 2010 and January 2011, thirty -two patients with cervical cancer were enrolled and treated with external beam radiotherapy (EBRT) and intracavitary brachytherapy (ICBT). The KKU-tube and CRT were applied intrarectally in the same patients at alternate sessions as references for calculation of rectal doses during ICBT. The gold standard references of rectum anatomical markers which are most proximal to radiation sources were anterior rectal walls (ARW) adjacent to the uterine cervix demonstrated by barium sulfate suspension enema. The calculated rectal doses derived from actual anterior rectal walls, CRT and the anterior surfaces of the KKU-tubes were compared by using the paired t-test. The pain caused by insertion of each type of rectal tube was assessed by the visual analogue scale (VAS). Results: The mean dose of CRT was lower than the mean dose of ARW ($Dmean_0-Dmean_1$) by $80.55{\pm}47.33cGy$ (p-value <0.05). The mean dose of the KKU-tube was lower than the mean dose of ARW ($Dmean_0-Dmean_2$) by $30.82{\pm}24.20cGy$ (p-value <0.05). The mean dose difference [($Dmean_0-Dmean_1$)-($Dmean_0-Dmean_2$)] was $49.72{\pm}51.60cGy$, which was statistically significant between 42.32 cGy -57.13 cGy with the t-value of 13.24 (p-value <0.05). The maximum rectal dose by using CRT was higher than the KKU-tube as much as 75.26 cGy and statistically significant with the t-score of 7.55 (p-value <0.05). The mean doses at the anterior rectal wall while using the CRTs and the KKU-tubes were not significantly different (p-value=0.09). The mean pain score during insertion of the CRT was significantly higher than the KKU-tube by a t-score of 6.15 (p-value <0.05) Conclusions: The KKU-model rectal tube was found to be an easily producible, applicable and reliable instrument as a reference for evaluating the rectal dose during ICBT of cervical cancer without negative effects on the patients.
Transactions of the Korean Society of Mechanical Engineers A
/
v.41
no.10
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pp.983-989
/
2017
This paper presents the bearing strength for laminates in advanced composite materials in bolted joints. Bolted single lap joint tests were experimentally investigated with respect to stabilized and unstabilized lap joints. Stabilized bolted single lap joints refer to joints with out-of-plane rotational constraints. Unstabilized bolted single lap joints refer to joints with absence of out-of-plane deflection constraints. The bearing strength values of laminates in the bolted joint showed that the percentages of ply angle for 0, 45, -45, and 90 degrees were not affected. The bearing strength value in the unstabilized bolted joint was smaller than the bearing strength value in the stabilized bolted joint because of the influence of the out-of-plane behavior. The composite material studied in this paper is a carbon/epoxy unidirectional (UD) tape prepreg cured at $177^{\circ}C(350^{\circ}F)$. In the laminate reference system, the standard angles of 0, 45, -45, and 90 degrees were used for ply orientation within the laminate. A total of 112 bolted single lap joint tests were conducted on specimens from eight distinct laminates. The ASTM-D-5961M standards were adhered to for the stabilized and unstabilized bolted single lap joint tests.
Background: This study was carried out to investigate the interaction of p53 codon 72 polymorphism, dietary and tobacco habits with reference to risk of stomach cancer in Mizoram, India. A total of 105 histologically confirmed stomach cancer cases and 210 age, sex and ethnicity matched healthy population controls were included in this study. Materials and Methods: The p53 codon 72 polymorphism was detected by PCR-RFLP and sequencing. H. pylori infection status was determined by ELISA. Information on various dietary and tobacco related habits was recorded with a standard questionnaire. Results: This study revealed that overall, the Pro/Pro genotype was significantly associated with a higher risk of stomach cancer (OR, 2.54; 95%CI, 1.01-6.40) as compared to the Arg/Arg genotype. In gender stratified analysis, the Pro/Pro genotype showed higher risk (OR, 7.50; 95%CI, 1.20-47.0) than the Arg/Arg genotype among females. Similarly, the Pro/Pro genotype demonstrated higher risk of stomach cancer (OR, 6.30; 95%CI, 1.41-28.2) among older people (>60 years). However, no such associations were observed in males and in individuals <60 years of age. Smoke dried fish and preserved meat (smoke dried/sun dried) consumers were at increased risk of stomach cancer (OR, 4.85; 95%CI, 1.91-12.3 and OR, 4.22; 95%CI, 1.46-12.2 respectively) as compared to non-consumers. Significant gene-environment interactions exist in terms of p53 codon 72 polymorphism and stomach cancer in Mizoram. Tobacco smokers with Pro/Pro and Arg/Pro genotypes were at higher risk of stomach cancer (OR, 16.2; 95%CI, 1.72-153.4 and OR, 9.45; 95%CI, 1.09-81.7 respectively) than the non-smokers Arg/Arg genotype carriers. The combination of tuibur user and Arg/Pro genotype also demonstrated an elevated risk association (OR, 4.76; 95%CI, 1.40-16.21). Conclusions: In conclusion, this study revealed that p53 codon 72 polymorphism and dietary and tobacco habit interactions influence stomach cancer development in Mizoram, India.
The H.264/AVC standard achieves higher coding efficiency than previous video coding standards with the rate-distortion optimization (RDO) technique which selects the best coding mode and reference frame for each macroblock. As a result, the complexity of the encoder have been significantly increased. In this paper, a fast intra-mode decision algorithm is proposed to reduce the computational load of intra-mode search, which is based on the inverse tree-structure edge prediction algorithm. First, we obtained the dominant edge for each $4{\times}4$ block from local edge information, then the RDO process is only performed by the mode which corresponds to dominant edge direction. Then, for the $8{\times}8$ (or $16{\times}16$) block stage, the dominant edge is calculated from its four $4{\times}4$ (or $16{\times}16$) blocks' dominant edges without additional calculation and the RDO process is also performed by the mode which is related to dominant edge direction. Experimental results show that proposed scheme can significantly improve the speed of the intra prediction with a negligible loss in the peak signal to noise ratio (PSNR) and a little increase of bits.
In this paper, we address issues associated with the real-time implementation of the MPEG-1/2 Layer-II (or MUSICAM) and MPEG-4 ER-BSAC decoders for Digital Multimedia Broadcasting (DMB) on TMS320C64x+ that is a fixed-point DSP processor with a clock speed of 330 MHz. To achieve the real-time requirement, they should be optimized in different steps as follows. First of all, a C-code level optimization is performed by sharing the memory, adjusting data types, and unrolling loops. Next, an algorithm level optimization is carried out such as the reconfiguration of bitstream reading, the modification of synthesis filtering, and the rearrangement of the window coefficients for synthesis filtering. In addition, the C-code of a synthesis filtering module of the MPEG-1/2 Layer-II decoder is rewritten by using the linear assembly programming technique. This is because the synthesis filtering module requires the most processing time among all processing modules of the decoder. In order to show how the real-time implementation works, we obtain the percentage of the processing time for decoding and calculate a RMS value between the decoded audio signals by the reference MPEG decoder and its DSP version implemented in this paper. As a result, it is shown that the percentages of the processing time for the MPEG-1/2 Layer-II and MPEG-4 ER-BSAC decoders occupy less than 3% and 11% of the DSP clock cycles, respectively, and the RMS values of the MPEG-1/2 Layer-II and MPEG-4 ER-BSAC decoders implemented in this paper all satisfy the criterion of -77.01 dB which is defined by the MPEG standards.
Park, Soobin;Choi, Kiho;Park, Sang-Hyo;Jang, Euee Seon
Journal of Broadcast Engineering
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v.18
no.2
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pp.178-184
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2013
In this paper, we propose an efficient parallelization technique of PU-level motion estimation (ME) in the next generation video coding standard, high efficiency video coding (HEVC) to reduce the time complexity of video encoding. It is difficult to encode video in real-time because ME has significant complexity (i.e., 80 percent at the encoder). In order to solve this problem, various techniques have been studied, and among them is the parallelization, which is carefully concerned in algorithm-level ME design. In this regard, merge estimation method using merge estimation region (MER) that enables ME to be designed in parallel has been proposed; but, parallel ME based on MER has still unconsidered problems to be implemented ideally in HEVC test model (HM). Therefore, we propose two strategies to implement stable parallel ME using MER in HM. Through experimental results, the excellence of our proposed methods is shown; the encoding time using the proposed method is reduced by 25.64 percent on average of that of HM which uses sequential ME.
Journal of the Korean Association of Geographic Information Studies
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v.10
no.4
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pp.46-59
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2007
Urban infrastructure is a core of urban growth management which concerns with location, time and costs of development. Despite an inevitable link between development density and infrastructure capacity in urban areas, little study have been performed. For this reason, development activities are undergone without any clear evidence or analysis. The main purposes of this paper are to build subject maps of urban infrastructure capacity which illustrate the level of education service and road capacity, and to give reference standard for development decision at given location. For these purposes, the case study of the high-rise multi-purpose buildings in Daegu metropolitan city is performed. The main findings are follows. First, road ratio is high in the CBD and its surrounding areas as well as rural area, and low in areas of manufacturing, parks and military use. Second, educational facility, represented by the number of student per classroom of elementary school, is fairly abundant across the city, especially in the CBD and rural areas. Third, the high-rise multi-purpose buildings have been built in population-losing infrastructure-abundant areas, in general. Based on these results, this study concludes that the high-rise multi-purpose buildings may induce population-inflow and have low possibility to bring about overly dense developments.
Journal of Korean Society of Environmental Engineers
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v.35
no.9
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pp.643-653
/
2013
In this study, trend analysis was performed by various runoff analysis method of Non-point Pollution Source(NPS) at the impervious area. The characteristics of rainfall at impervious area appeared to be influenced by rainfall strength and it appeared that first flush phenomenon occurs often if rainfall strength acts largely. It is judged that the measure is required to be prepared against that now that concentration difference of non-point pollution source appeared to be big by precedent number of days of no rainfall. As the result of calculating Decrease Rate (DR) by first flush of non-point pollution source, it is judged that it is important to prepare the measure against the pollutants about initial rain and it is necessary to calculate the capacity of non-point pollution source processing facilities regarding that now that the non-point pollution source integrated at impervious area showed the characteristics that are flowed out in high concentration by initial rain in case of non-rainfall considering the characteristics of non-point pollution source at impervious area. When taking 50% of non-point pollution source as the standard for decrease rate that was evaluated previously, it appeared as 15~60 min in case of TSS and it appeared as 30~90 min in case of organic compound, but the characteristic whose decrease rate is below 50% also appeared even till rainfall-runoff ends. Based on that, it is judged that it could be used as the reference when designing the structural BMPs facilities later.
In this study, inorganic elemental distribution in Korean adult human tissue of liver, lung, muscle, kidney, rib and thyroid has been investigated. These tissues were collected from human's body within 48 hours after their death according to IAEA's recommended method, dried by freeze drying method and then pulverized. Neutron activation analysis was applied to these samples to determine the concentrations of 5 major elements of Ca, Mg, Na, K, and Cl and 12 trace elements of Mn, I, Sr, As, Br, Co, Cr, Cs, Fe, Rb, Se, and Zn. To confirm accuracy of analytical result was performed using three kinds of standard reference materials and resulted that the relative error is within 10% for the most of elements and the Z-score indicating a performance of analysis is within 2. The elemental distribution shows that the major elements are distributed homogeneously with a specific concentration and that the trace elements shows a distribution of different concentration with kinds of tissue and their age. Particularly, iodine shows higher concentration with 1000 ${\mu}g/g$ in thyroid, and calcium and strontium show the concentration with 15.9% and 84.4 ${\mu}g/g$ in rib, respectively.
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