• Mass Spectrometry Letters
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• v.8 no.3
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• pp.53-58
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• 2017

Glycated hemoglobin ($HbA_{1c}$) has been commonly used to screen and diagnose for patients with diabetes mellitus. Here the accelerated procedure of microwave-assisted sample treatment from acid hydrolysis to enzyme digestion followed by isotope dilution liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS) was optimized and applied to measure $HbA_{1c}$ in an effort to speed up analysis time. First, two signature peptides of $HbA_{1c}$ and hemoglobin $A_0$ were certified with amino acid analysis by setting optimized acid hydrolysis conditions to $150^{\circ}C$, 1.5 h and $10{\mu}M$ sample concentration in 8 M hydrochloric acid. Consequently, the accurate certified peptides above were used as calibration standards to implement the proteolytic procedure with endoproteinase Glu-C at $37^{\circ}C$, 700 W for 6 h. Compared to the traditional method, the microwave heating not only shortened dramatically sample preparation time, but also afforded comparable recovery yields. The optimized protocol and analytical conditions in this study are suitable for a primary reference method of $HbA_{1c}$ quantification with full SI-traceability and other similar proteins in complex biological samples.

• Journal of The Korean Astronomical Society
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• v.43 no.6
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• pp.191-200
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• 2010

We present the Korea Institute for Advanced Study Value-Added Galaxy Catalog (KIAS VAGC), a catalog of galaxies based on the Large Scale Structure (LSS) sample of New York University Value-Added Galaxy Catalog (NYU VAGC) Data Release 7. Our catalog supplements redshifts of 10,497 galaxies with 10 < $r_P\;{\leq}\;17.6$ (1455 with 10 < $r_P\;{\leq}\;14.5$) to the NYU VAGC LSS sample. Redshifts from various existing catalogs such as the Updated Zwicky Catalog, the IRAS Point Source Catalog Redshift Survey, the Third Reference Catalogue of Bright Galaxies, and the Two Degree Field Galaxy Redshift Survey have been put into the NYU VAGC photometric catalog. Our supplementation significantly improves spectroscopic completeness: the area covered by the spectroscopic sample with completeness higher than 95% increases from 2.119 to 1.737 sr. Our catalog also provides morphological types of all galaxies that are determined by the automated morphology classification scheme of Park & Choi (2005), and related parameters, together with fundamental photometry parameters supplied by the NYU VAGC. Our catalog contains matches to objects in the Max Planck for Astronomy (MPA) & Johns Hopkins University (JHU) spectrum measurements (Data Release 7). This new catalog, the KIAS VAGC, is complementary to the NYU VAGC and MPA-JHU catalog.

• Journal of the Korean Society of Tobacco Science
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• v.23 no.1
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• pp.45-52
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• 2001

This study was carried out to evaluate the uncertainty in the analysis of total alkaloids and reducing sugar content in flue-cured tobacco. The sources of uncertainty associated with the analysis of total alkaloids and reducing sugar were the weighing of sample, the preparation of extracting solution, the addition of extracting solution into the sample, the preparation of standard solution, the precision of calibration curve for standard solution, the reproducibility of analysis, and the determination of water content in tobacco, etc. For the calculating uncertainties, Type A of uncertainty was evaluated by the statistical analysis of a series of observation, and Type B by the information based on supplier’s catalogue and/or certificated of calibration. It was shown that the main source of uncertainty was caused by the calibration curve of standard solution, the reproducibility of analysis, the volume measurement of 1$m\ell$, and the purity of nicotine reference material in the preparation of standard solution. The uncertainty in the addition of extracting solution, the sample weighing, the volume measurement of 100$m\ell$, and the determination of water content of tobacco contributed relatively little to the overall uncertainty. The expanded uncertainty of total alkaloids and reducing sugar in flue-cured tobacco at 95% level of confidence was $\pm$0.12% and $\pm$0.54%, respectively.

• Proceedings of the IEEK Conference
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• 2000.11d
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• pp.115-118
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• 2000

We present a new variable step size LMS algorithm using the correlation between reference input and error signal of adaptive filter. The proposed algorithm updates each weight of filter by different step size at same sample time. We applied this algorithm to adaptive multip]e-notch filter. Simulation results are presented to compare the performance of the proposed algorithm with the usual LMS algorithm and another variable step algorithm.

• Proceedings of the Optical Society of Korea Conference
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• 2002.07a
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• pp.170-171
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• 2002

근래에 광통신의 속도가 10Gbps 이상 증가하면서, 고려하지 않았던 편광과 관련된 현상이 원거리 광통신 시스템에 많은 문제점을 유발하게 되었다. 특히 편광의존손실(PDL)은 시스템의 BER과 신호 왜곡을 가중시켜 시스템 성능을 저하시킨다. 이러한 PDL을 시스템 상에서 보정하는 것은 매우 복잡하고 어렵기 때문에 광 부품 제조 단계에서 PDL을 작게 되도록 해야하며, 이를 위해 정확한 PDL을 측정이 요구된다. (중략)

• Proceedings of the KIEE Conference
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• 2009.07a
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• pp.1260_1261
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• 2009

A detailed investigation and structure of tested samples are clearly presented. As a reference, $Ge_1Se_1Te_2$/Sb only sample was also investigated. We used compound of Ge-Se-Te material for phase-change cell. Actually, the performance properties have been improved surprisingly then conventional Ge-Sb-Te. However, crystallization time was as long as ever for amorphization time. We conducted this esperiment in order to solve that problem by doping-Sb.

• Communications for Statistical Applications and Methods
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• v.6 no.2
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• pp.645-658
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• 1999

One of the most popular graphical techniques for goodness of fit problems is the quantile-quantile plot(Q-Q plot) Easton and McCulloch(1990) suggested a way of generalizing Q-Q plots to multivariate cases bases on finding a matching between the points of the data set whose shape is being examined and a reference sample. in this paper we investigated the asymptotic behavior of the generalized Q-Q plot for bivariate cases. As a result we concluded that the standard univariate Q-Q plot and the generalized Q-Q plot have the same limit if two variables are independent.

• Proceedings of the KIEE Conference
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• 1989.11a
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• pp.176-179
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• 1989

Newton's OPF algorithm, for each iteration, solves with second order approximation of Lagraqngian function and sparse matrix technique. When load model is applied to this technique, load voltages have tendency to be fixed at lower limit. It makes the solution inadequte. In this paper, reference bus voltage specification technique suggested to make adequate load voltage. This method is verified useful 6-bus Ward-Hale sample system.

• 한국데이터정보과학회:학술대회논문집
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• 2003.05a
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• pp.89-95
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• 2003

Cumulative sum(CUSUM) control charts for monitoring dispersion matrix under multivariate normal process are proposed. Performances of the proposed CUSUM charts are measured in terms of average run length(ARL) by simulation. Numerical results show that small reference values of the proposed CUSUM chart is more efficient for small shifts in the production process.

• Proceedings of the IEEK Conference
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• 2003.07a
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• pp.310-313
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• 2003

Complex permittivities of human head simulating liquids were measured by a sample holder of terminated slotted coaxial line with a movable probe at mobile communication frequencies. The validity of the liquid measurement system was checked by experiments with the reference liquids. Liquids of ingredients for human brain suggested in IEEE draft and those made by the authors were measured by this slotted line system.