• Bulletin of the Korean Chemical Society
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• 제33권11호
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• pp.3601-3606
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• 2012

Structural properties of a small hexapeptide molecule modeled after metal-binding siderochrome immersed in a room-temperature ionic liquid (RTIL) are studied via molecular dynamics simulations. We consider two different RTILs, each of which is made up of the same cationic species, 1-butyl-3-methylimidazolium ($BMI^+$), but different anions, hexafluorophosphate ($PF_6{^-}$) and chloride ($Cl^-$). We investigate how anionic properties such as hydrophobicity/hydrophilicity or hydrogen bonding capability affect the stabilization of the peptide in RTILs. To examine the effect of peptide-RTIL electrostatic interactions on solvation, we also consider a hypothetical solvent $BMI^0Cl^0$, a non-ionic counter-part of $BMI^+Cl^-$. For reference, we investigate solvation structures in common polar solvents, water and dimethylsulfoxide (DMSO). Comparison of $BMI^+Cl^-$ and $BMI^0Cl^0$ shows that electrostatic interactions of the peptide and RTIL play a significant role in the conformational fluctuation of the peptide. For example, strong electrostatic interactions between the two favor an extended conformation of the peptide by reducing its structural fluctuations. The hydrophobicity/hydrophilicity of RTIL anions also exerts a notable influence; specifically, structural fluctuations of the peptide become reduced in more hydrophilic $BMI^+Cl^-$, compared with those in more hydrophobic $BMI^+PF_6{^-}$. This is ascribed to the good hydrogen-bond accepting power of chloride anions, which enables them to bind strongly to hydroxyl groups of the peptide and to stabilize its structure. Transport properties of the peptide are examined briefly. Translations of the peptide significantly slow down in highly viscous RTILs.

• 교육시설 논문지
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• 제22권2호
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• pp.3-13
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• 2015

The policy of the Ministry of education through the social awareness and issues are being changed. Accordingly, in response to the school building which also has to be changed. This study is Low-floor(1~2 floor) for high accessibility, important management and a lot of locomotion. This study is analysis by floor of newly established schools in Chungbuk. Facility and space on the possible low-floor situated are classified administrative zone, health zone, student support + local exchange zone, STEAM(creativity, personality) supporting zone. The administrative area includes administration office, principal's office and board rooms. The administrative zone is located against schoolyard. Because it is possible visual control of schoolyard. also it controls visitor access so it is placed near main entrance. Health zone is located near a special class, counseling center and wee class for emergency situation. and is located near schoolyard for visual control. Student support + local exchange area includes library and computer lab, audio-visual room, auditorium or gymnasium. It put more emphasis resident welfare, culture and education. So it opens for local residents. It is located center of few stories or near entrance. STEAM(creativity, personality) supports science lab, art room, family room. It is possible such a theory class, experience class and indoor and outdoor class. It is located few floors. This study is used as a reference for school building projects planing.

• 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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• 제29권4호
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• pp.29-35
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• 2023

Purpose: The 2015 Middle East Respiratory Syndrome (MERS) outbreak and the recent COVID-19 pandemic have highlighted the lack of negative pressure isolation rooms and the fragility of the healthcare system. The need for healthcare facility transformation for respiratory infectious diseases has become more prominent due to COVID-19, and the purpose of this study is to provide a foundation for the rapid, economical, and safe construction of negative pressure isolation wards. Methods: This study analyzes the current status of hospitals that have been converted to negative pressure isolation rooms, and provides architectural plans and examples to provide a reference for bedroom change. Research data of this study have been obtained by analyzing the drawings of negative pressure isolation wards of nationally designated inpatient treatment beds and urgent isolation beds. In addition, the relevant literature of urgent isolation beds has been analyzed to derive bedroom change type. Result: In this study, a total of 21 isolation bed conversion methods have been presented. Implications: In order to change efficiently from a general ward to an isolation ward, it is necessary to consider the actual hospital's infectious disease transmission patterns and facility conditions.

• Journal of Nutrition and Health
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• 제54권5호
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• pp.425-434
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• 2021

The discovery of the relationship between nutrients and deficiency diseases during the 100 years from the mid-1800s to the mid-1900s was a breakthrough that led to advances in the study of nutrition. The Recommended Dietary Allowances (RDA) were created as a quantitative standard for avoiding diseases caused by nutrient deficiency. In addition, a reductionism paradigm has become generally accepted among nutrition scholars in health and disease, which focused on the properties of individual nutrients, content in foods, cellular levels, and mechanisms of action. The reductionist paradigm worked very well for the prevention and treatment of malnutrition diseases. However, as the incidence of nutrient deficiencies decreased and that of chronic diseases increased, the nutrition goals have been changed to secure safe and adequate nutrient intake and to reduce chronic disease risks. Accordingly, Dietary Reference Intakes (DRIs), a set of nutrient-based reference values, were designed to replace the RDA. The revised Korean DRIs were published for 40 nutrients in 2020. However, there is still room for improvement in the reference intake levels targeted at reducing the risk of chronic disease. The reductionist approach can no longer be practical because chronic diseases are related to the interactions between multi-components in the foods and multi-targets in the body. Therefore, a second innovative leap is needed following the nutrition development breakthrough made over 100 years ago. To this end, the nutrition paradigm must evolve from reductionism to a holism approach. Cutting-edge scientific technologies, such as metabolomics, transcriptomics, microbiomics, and bioinformatics, should also be acceptable in nutrition science based on the knowledge gained from basic nutrition studies.

• 대한수의학회지
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• 제30권1호
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• pp.103-106
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• 1990

Effects of ammonia water on the spornlation of coccidial oocysts collected from bovine feces were studied with particular reference to the various levels of ammonia water (1% to 10%) for 30 minute conservation at room temperature. The sporulation rates showed a negative linear coorelation according to the treatment leavels of ammonia water, 85.3% at 1% level to 8.9% at 10% level. The optimum level of ammonia concentration was regarded as 5% to 10% with more than 80% of sporulation inhibition effect.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1997년도 한국자동제어학술회의논문집; 한국전력공사 서울연수원; 17-18 Oct. 1997
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• pp.516-519
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• 1997

In this paper, the control of the temperature for the vehicle air conditioner is implemented with the fuzzy controller using a micro controller. The linguistic control rules of the fuzzy controller are separated into two out variables(multi input multi output ; MIMO) : one is those for the blower motor, and the other is those for air mix door. The error in fuzzy controller, the input variable is defined as difference between the reference temperature and the actual temperature in the cabin room. The fuzzy control rules are established from the human operator experience, and based engineering knowledge about the process. The method of the center of gravity is utilized for the defuzzification.

• International Journal of Korean Welding Society
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• 제5권1호
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• pp.29-34
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• 2005

Finite element analysis (FEA) and experimental studies on an elastic bending method have been performed in order to control the angular distortion at the fillet weldment for curved panel. Process parameters for the elastic bending method such as clamping span and release time were analyzed with reference to welding condition and geometric effect of the curved panel, which can minimize or prevent the angular distortion by producing a proper skin stress to the fillet weldment. The amounts of the angular distortion decrease almost in a linear manner with an increase in the skin stress. The skin stress required for non-angular distortion at the fillet weldment is strongly dependent on the plate thickness, not the heat intensity applied. The clamping span for obtaining uniform skin stress was defined as functions of the plate thickness and length of the free edge. Clamp should be removed after the fillet weldment is cooled down to room temperature for non-angular distortion. Effectiveness of the elastic bending method established was verified by its application to an actual curved panel.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2009년도 정보 및 제어 심포지움 논문집
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• pp.350-353
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• 2009

The shielding enclosure is very essential device to test the electromagnetic wave power generated by various RF equipments. Some standards for the shielding enclosures were established to test them in right method. Generally, There are IEEE-STD-299 and MIL-STD-285 and NSA-65-6 of the method for measuring the effectiveness of shielding enclosures, the IEEE-STD-299 combined MIL-STD-285 and NSA-65-6 about the method for measuring shielding effectiveness(SE) about 1969 years, but, the measurement point of 299 proposal is many points(including shielding wall, seam, coner beat, shielding door, etc) and demand long time of measurement. To improve SE test method for shielding enclosures was studied and suggested to develop a proper test procedure. First, we measure reference level as frequency range and H/V polarization, secondly, measure leakage point, and finally, measure shield effect and calculate SE. Our method has a merit of the less measurement point than IEEE-STD-299, and shorten time than 299, and define representation SE of shielding enclosure effectively.

• 대한기계학회논문집B
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• 제20권5호
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• pp.1679-1688
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• 1996

Laser flash technique was applied to measure thermal properties of FGM made by a CVD method. System stability and reproducibility of this measuring system were proved and calibrated with glassy carbon used as reference material. Specimens was prepared by cutting FGM diagonally. Measurements were performed for a wide range of temperatures up to 1500K. Relative heat capacity of the FGM specimen was scattered with in $\pm$13% at room temperature and at high temperature above 1200K, and $\pm$3% at medium temperature range. On the other hand, thermal diffusivity data showed excellent reproducibility and stability through the whole temperature range. In conclusion, the multi-target radiometer can be applied to measure the thermal properties of non homogeneous materials like FGM.

• 수산해양기술연구
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• 제24권1호
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• pp.30-35
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• 1988

An electrical power generation system driven by main engine shaft, briefly SG system for middle or small size fishing boat is studied experimently. In the SG system, power transmission is performed by a variable displacement hydraulic pump driven by the main engine and a constant displacement hydraulic motor. It was verified that the SG system enabled the generation of electrical power with constant frequency regardless main engine speed. In the SG system, setting reference frequency, sensing generator output frequency and setting controller parameters are performed by performed by programming in a microcomputer, so a countermeasure for physical situations of control object is very easy. Futhermore, the SG system has following features; low initial installation cost, wide freedom of installation in engine room, advantage of application in existing ships, especially fishing boat with hydraulic fishing equipments.