• 동의신경정신과학회지
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• 제21권3호
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• pp.29-44
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• 2010

Objectives : The purpose of this research is to examine the efficacy of Gamisoyosan on anxiety of generalized anxiety disorder according to dosage form. Methods : In this randomized, double blinded, placebo-controlled study, we planned to give Gamisoyosan simple extract mixture or Gamisoyosan compound extract or controlled medication for major symptoms of generalized anxiety disorder. As preparatory research, Hamilton rating Scale for Anxiety(HAM-A) was measured as the 1st evaluative instrument, and Korean State-Trait Anxiety Inventory(STAI-K), Penn State Worry Questionnaire(PSWQ) Korean Beck's Depression Inventory (BDI-K), Symptom Checklist-90-Revised(SCL-90R), WHO Quality of Life Abbreviated(WHOQOL-BREF) and Heart Rate Variability(HRV) were also measured as the 2nd evaluative instrument at the before treatment. Results : Demographic characteristics showed that there are Clinical characteristics-vital signs are within the normal range. The characteristics of disease-chief complaint, pattern Identification and etiological factor of the highest frequency number were worry, heart deficiency with timidity(心膽虛怯), family matters. The average period of disease in subjects is 6.31years. The results of Chest PA, EKG and clinicopathologic examination are within the reference range. The Scores of HAM-A, STAI-K, PSWQ were measured above the cutoff point. There are significant positive correlations among HAM-A, STAI-K, BDI-K and among HAM-A, STAI-K, PSWQ. There are no significant correlations between PSWQ and BDI-K. Conclusions : We considered that selection of subjects in this research is appropriately accomplished And this methodology is expected to be applied to the subsequent research. And also, we hope to make up for this study through various study and discussion.

• Journal of Animal Science and Technology
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• 제62권2호
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• pp.141-158
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• 2020

Skin is a major thermoregulatory organ in the body controlling homeothermy, a critical function for climate adaptation. We compared genes expressed between tropical- and temperate-adapted cattle to better understand genes involved in climate adaptation and hence thermoregulation. We profiled the skin of representative tropical and temperate cattle using RNA-seq. A total of 214,754,759 reads were generated and assembled into 72,993,478 reads and were mapped to unique regions in the bovine genome. Gene coverage of unique regions of the reference genome showed that of 24,616 genes, only 13,130 genes (53.34%) displayed more than one count per million reads for at least two libraries and were considered suitable for downstream analyses. Our results revealed that of 255 genes expressed differentially, 98 genes were upregulated in tropically-adapted White Fulani (WF; Bos indicus) and 157 genes were down regulated in WF compared to Angus, AG (Bos taurus). Fifteen pathways were identified from the differential gene sets through gene ontology and pathway analyses. These include the significantly enriched melanin metabolic process, proteinaceous extracellular matrix, inflammatory response, defense response, calcium ion binding and response to wounding. Quantitative PCR was used to validate six representative genes which are associated with skin thermoregulation and epithelia dysfunction (mean correlation 0.92; p < 0.001). Our results contribute to identifying genes and understanding molecular mechanisms of skin thermoregulation that may influence strategic genomic selection in cattle to withstand climate adaptation, microbial invasion and mechanical damage.

• 한국초등과학교육학회지:초등과학교육
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• 제20권1호
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• pp.59-73
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• 2001

The National Science Fairs has been held in every year for the promotion of science and technology and scientific civil life. The purpose of this study is to survey the current problems in National Science Fairs by making up a question and to improve them. The study makes up a questionnaires about the existing Science Fairs to the teachers who have submitted their works to the Science Fairs and suggest the ways of improvement. The result of questionnaires is that little availability of reference materials, difficulty of paying proper attention to regular classes because of frequent travels, and absence of experimental devices and experimental rooms are perceived as major obstacles in preparing for the exhibition. Respondents teacher also pointed out some problems with the current organization of the exhibition; non-voluntary selection process for the potential authors, separation of research content from regular teaching materials, unrealistically high standard, low participation rate of teachers, so many exhibited works, lack of professionalism in the screening process. The majority however, agreed that the exhibition event should be continuously done, after remedial measures have been taken about the problems. First, the side of science education is emphasized in a purpose of the science fairs to let activity related to science fair be closely connected with school education. Second, students have to be divided according to grade. Third, research level have to be set not too higher than regular instruction content. Fourth, hand book related to science fairs have to be manufactured and spread. Fifth, data of local science fair have to be arranged. Sixth, judging section have to be subdivided and people related to science education have to be included to a judge. Seventh, excellent works have to be support to participate in ISEF.

• 전자공학회논문지SC
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• 제46권6호
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• pp.21-27
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• 2009

휴대형 전자정보기기의 사용이 보편화되면서 고성능 전지를 개발하는 노력이 활발하게 진행되고 있는 등, 휴대형 장치에 전력공급 시간을 증대시키는 것이 중요한 문제로 대두되었다. 전력공급 시간의 연장을 위한 또 하나의 실용적 방법은 다중전지를 병렬 연결하여 사용하는 것이다. 본 논문에서는 다중전지를 사용하되, 단순한 병렬 연결이 아니라 전지 내부의 잔류 에너지를 재활용하는 새로운 발상을 소개하고자 한다. 이 방식은 전지의 사용에 따라 출력 전압이 기준값 이하로 떨어진 후라 할지라도 일정한 길이의 휴지시간을 경과하고 나면 잔류 에너지에 의하여 전압이 다시 일부분 회복되는 실제적 현상을 이용하려는 것이다. 잔류 에너지를 재활용할 수 있는 구체적인 방법으로서 전지선택형 다중전지 결합 방식을 제안하였다. 제안한 방식에 대하여 전지 방전특성을 실험적으로 측정하였으며, 알카라인 일차전지 한 개당 진력공급 시간을 1~2시간 정도 더 연장시킬 수 있음을 확인하였다.

• 대한건축학회논문집:구조계
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• 제35권10호
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• pp.225-234
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• 2019

The purpose of this paper is to analyze the additional construction cost of G-SEED certification for domestic office building reflecting the latest standard(G-SEED 2016-2), and to derive cost impact by category and level. Therefore, it is intended to provide quantitave cost data according to G-SEED certification at the planning phase of the project, estimate the additional construction cost per level according to G-SEED Certification of similar project to be carried out in the future, and encourage G-SEED certification by supporting the decision of the owners. Method: The Process and method of this study are summarized in five steps, 1) Review of previous research, 2) Selection of target project, 3) Scenario setting by level, 4) Additional construction cost for each evaluation category, 5) Extraction of additional construction cost ratio by level. Result: This paper analyzed the cost impact by deriving the additional construction cost of detailed category for level improvement according to the revised G-SEED certification(G-SEED 2016-2). In conclusion, an additional construction cost(ratio) of G-SEED projects to the reference building is drawn as good level; 157,426,241 KWN(+0.43%), very good level; 321,907,802 KWN(+0.88%), excellent level; 999,371,478 KWN(+2.74%), and outstanding level; 1,467,047,718 KWN(+4.02%).

• 한국구조물진단유지관리공학회 논문집
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• 제24권5호
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• pp.27-36
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• 2020

이 논문의 목적은 말뚝식 계류시설에 대해 현행 실무에서 주로 적용하고 있는 응답스펙트럼 해석법에서 표준설계응답스펙럼의 적용성에 대해 연구하는 것이다. 이를 위하여 다양한 지층조건을 고려한 Proshake 1차원 부지응답을 수행하여 현행 표준설계응답스펙트럼과 비교하고, Abaqus를 활용한 지반-말뚝 모델링으로 시간이력해석을 수행하여 지반-말뚝 동적거동 특성을 분석하였으며, 잔교시설이 설치되는 경사지반에 대해 Abaqus를 활용한 2차원 부지응답해석을 수행하여 응답스펙트럼의 기준면 선정방안을 검토하였다. 연구 결과 말뚝식 계류시설의 지반-말뚝 동적거동 특성과 경사지반의 특성을 고려할 경우 현행 표준설계응답스펙트럼의 적용성에 문제가 있으며 개선이 필요하다는 것을 확인하였다.

• Geomechanics and Engineering
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• 제27권6호
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• pp.537-550
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• 2021

There are various technical problems need to be solved in the construction process of pre-setting an isolation wall into a double lane in the outburst prone mine. This study presents a methodology that pre-setting an isolation wall into a double lane without a coal pillar. This requires the excavation of two small section roadways to dig a wide section roadway, followed by construction of the separation wall. During this process the connecting lane is reserved. In order to ensure the stability of the separation wall, the required bearing capacity of the isolation wall is 4.66 MN/m and the deformation of the isolation wall is approximately 25 cm. To reduce the difficulty of implementing support the roadway is driven by 5 m/d. After the construction of the separation wall, the left side coal wall is brushed 1.5 m to make the width of the gas roadway reach 2.5 m and the roadway support utilizes anchor rod, ladder beam, anchor cable beam and net configuration. During construction, the concrete pump and removable self-propelled hydraulic wall mold are used to pump and pour the concrete of the isolation wall. In the process of mining, the stress distribution of coal body and isolation wall is detected and measured on site. The results demonstrate that the deformation of the surrounding rock of roadway and separation of roof in the roadway is small. The stress of the bolt and anchor cable is within equipment tolerance validating their selection. The roadway is well supported and the intended goal is achieved. The methodology can be used for reference for similar mine gas control.

• Structural Engineering and Mechanics
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• 제86권4호
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• pp.487-501
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• 2023

Nanoparticles have lower size and larger specific surface area, good stability and less toxic and side effects. In recent years, with the development of nanotechnology, its application range has become wider and wider, especially in the field of biomedicine, which has received more and more attention. Bone defect repair materials with high strength, high elasticity and high tissue affinity can be prepared by nanotechnology. The purpose of this paper was to study how to analyze and study the composite materials for sports bone injury based on multifunctional nanomaterials, and described the electrospinning method. In this paper, nano-sized zirconia (ZrO₂) filled micro-sized hydroxyapatite (HAP) composites were prepared according to the mechanical properties of bone substitute materials in the process of human rehabilitation. Through material tensile and compression experiments, the performance parameters of ZrO₂/HAP composites with different mass fraction ratios were analyzed, the influence of filling ZrO₂ particles on the mechanical properties of HAP matrix materials was clarified, and the effect of ZrO₂ mass fraction on the mechanical properties of matrix materials was analyzed. From the analysis of the compressive elastic modulus, when the mass fraction of ZrO₂ was 15%, the compressive elastic modulus of the material was 1222 MPa, and when 45% was 1672 MPa. From the analysis of compression ratio stiffness, when the mass fraction of ZrO₂ was 15%, the compression ratio stiffness was 658.07 MPa·cm³/g, and when it was 45%, the compression ratio stiffness is 943.51MPa·cm³/g. It can be seen that by increasing the mass fraction of ZrO₂, the stiffness of the composite material can be effectively increased, and the ability of the material to resist deformation would be increased. Typically, the more stressed the bone substitute material, the greater the stiffness of the compression ratio. Different mass fractions of ZrO₂/HAP filling materials can be selected to meet the mechanical performance requirements of sports bone injury, and it can also provide a reference for the selection of bone substitute materials for different patients.

• 대한한방부인과학회지
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• 제26권4호
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• pp.191-203
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• 2013

Purpose: This review is to figure out evidence that suggest effectiveness of Korean Medicine treatments against cervical dysplasia. Methods: Studies on cervical cancer and cervical dysplasia were searched through 6 databases: Korean Studies Information Service System(KISS), National Discovery for Science Leaders (NDSL), Korea Institute of Science and Technology Information (Korean TK), Oriental Medicine Advanced Searching Integrated System (OASIS), the Journal of Korean Medicine, and the Journal of Korean Obstetrics & Gynecology. After that, the articles were extracted with reference point of Korean Traditional Medicine. Results: 37 articles were included lastly according to selection criteria. 3 of them were case reports on cervical dysplasia, and 34 were in-vitro studies on Human Papilloma Virus (HPV) positive cancer cell. In case reports, acupuncture, moxibustion, medical herbs and pharmacoacupuncture were used for treatments of cervical dysplasia with about 3 months. Experimental studies on cervical cancer cell showed that several herbs function with clear heat, eliminate stasis (淸熱解毒, 化瘀消腫) have anti-cancer effects inducing apoptosis. Conclusions: The results of articles are not enough to use in practice. Therefore, we indicates more advanced research methodology as follows: development of Korean Medicine treatment protocol with oral and external, in-vivo experimental study, and evaluation immunity index.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제7권10호
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• pp.2430-2447
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• 2013

In recent years, HTTP adaptive streaming (HAS) has attracted considerable attention as the state-of-the-art technology for video transport. HAS dynamically adjusts the quality of video streaming according to the network bandwidth and device capability of users. Content-Centric Networking (CCN) has also emerged as a future Internet architecture, which is a novel communication paradigm that integrates content delivery as a native network primitive. These trends have led to the new research issue of harmonizing HAS with the in-network caching provided by CCN routers. Previous research has shown that the performance of HAS can be improved by using the H.264/SVC(scalable video codec) in the in-network caching environments. However, the previous study did not address the misbehavior that causes video freeze when overestimating the available network bandwidth, which is attributable to the high cache hit rate. Thus, we propose a new SVC-based adaptation algorithm that utilizes a drop timer. Our approach aims to stop the downloading of additional enhancement layers that are not cached in the local CCN routers in a timely manner, thereby preventing excessive consumption of the video buffer. We implemented our algorithm in the SVC-HAS client and deployed a testbed that could run Smooth-Streaming, which is one of the most popular HAS solutions, over CCNx, which is the reference implementation of CCN. Our experimental results showed that the proposed scheme (SLA) could avoid video freeze in an effective manner, but without reducing the high hit rate on the CCN routers or affecting the high video quality on the SVC-HAS client.