• 정보관리학회지
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• 제3권2호
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• pp.42-74
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• 1986

우리나라 대학도서관에서 정보서비스의 수준을 높이기 위하여 필수적으로 요청되는 것이 정보서비스의 주체인 정보사서의 질을 높여야 한다는 이론을 규명하기 위하여, 우러나라 대학도서관의 정보서비스 현황과 정보사서의 현황을 통계적으로 상세히 분석하였다. 그 결과, 우리나라 정보사서들은 도서관학사학위를 소지한 20대와 30대의 인사들로 주성되어 있었으며, 주제전문사서로 볼 수 있는 비율은 7.6%에 불과했고, 즉답형 질문(42.1%)과, 지시형 질문(32.7%)을 주로 해답하여 주며, 정보서비스의 수준을 향상시키기 위하여 주제전문사서제도를 채택하는 것이 절대 바람직하다고 응답하였다. 주제전문사서가 수행하여야 할 주요 기능은 특정주제분야의 정보서비스, 서지, 안내서, 도서목록, 색인, 초록등의 작성; 정보배포와 최신정보주지 서비스; 균형있는 장서구성; 학과단위, 학생 및 교수와의 긴밀한 교량적 역할; 독장에 대한 자료 및 도서관 이용의 정규 비정규직인 강의와 안내; 및 분류편목의 순서라고 응답하였다. 주제전문사서를 양성하기 위한 가장 좋은 교육제도는 도서관학사를 하여금 대학원에 진학하여 주제전문가로서의 소양을 쌓도록 하여 도서관학석사학위를 수여 하는 것이 바람직하다고 분석되었으며, 주제전문사서제도가 확립되어야만 대학사서의 교수신분을 확보할 수 있다고 보았다.

• Spatial Information Research
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• 제23권5호
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• pp.53-64
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• 2015

디지털시대에 다양한 분야에서 공간정보를 공유하기 위해 여러 국가들은 NSDI를 구축하고 있다. NSDI의 중요한 요소 중 하나는 기본공간정보로 다양한 분야에서 공통으로 공유되는 공간정보(콘텐트)를 의미한다. 여러 연구들이 공간정보 분야 전문가, 사용자 등을 대상으로 한 선호빈도 조사, 외국 사례조사 등으로 기본공간정보 구성항목을 제안하고 있다. 그러나 이와 같은 방법은 기본공간정보 항목 선정결과에 대한 객관적인 검증이 미흡하다. 본 연구는 요인분석을 이용한 통계적 검증을 통해 다양한 분야에서 공통으로 공유되는 실체로 공간정보(콘텐트)가 무엇인지를 분석한다. 이를 위해 우리나라에서 가장 많이 사용되는 국가기본도의 중분류 레이어 104개와 그 외에 다양한 분야에서 많이 사용하는 지적, 영상 등을 포함해 총 109개 레이어의 활용행태를 조사한다. 조사내용은 기본공간정보 활용행태의 특성인 배경자료, 기준자료, 기초자료로서 각 레이어가 사용되는 정도이다. 그리고 이외 다른 목적으로 사용빈도가 높은 기타의 경우를 조사한다. 요인분석 결과 각 활용행태에 따라 5-7개 요인집단들이 도출되었다. 각 활용행태의 요인집단에 대한 분산분석 결과 집단의 평균값 사이에 통계적으로 유의한 차이가 있는 것으로 나타났다. 그리고 각 활용행태에서 평균값이 높은 요인집단의 레이어 항목들은 거의 동일하다고 할 만큼 유사하다. 이와 같은 결과를 바탕으로 본 연구는 교통(도로, 철도), 건물, 수계, 고도, 행정구역, 영상, 측량기준, 지적 등 8개의 주제를 중심으로 기본공간정보 구성체계를 제안한다. 본 연구에서 제안한 기본공간정보를 구성하는 주제정의는 공간정보 공유체계를 구축하는 시작의 단추로 의미가 있다. 제안된 기본공간정보가 다양한 분야에서 공유되기 위해서 실제 표준 형태로 구축되고 유통되는 체계를 갖추어야 하며, 이와 관련된 연구들이 이루어져야 한다.

• 디지털융복합연구
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• 제15권12호
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• pp.489-494
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• 2017

게임 애니메이션은 영상 애니메이션과 제작 과정에서 많은 차이가 있지만, 컴퓨터에서 작업하는 애니메이팅 방식은 크게 다르지 않다. 게임 애니메이션 제작에서도 영상 애니메이션에서의 원칙과 원리가 강조되어 제작되기 때문이다. 본 연구에서는 게임 애니메이션 제작 시 캐릭터의 포즈작업에 있어 여러 가지 고려해야 할 사항들 중, 동작의 방향과 에너지의 흐름을 알 수 있는 Line of Action에 대하여 고찰하고자 한다. Line of Action은 드로잉의 기초 이론으로 시작하여 셀 애니메이션부터 3d 애니메이션까지 포즈 작업에 있어 바이블의 역할을 하고 있다. 이러한 Line of Action이 게임 캐릭터의 포즈 작업에서 어떻게 적용되는지 알아보고자 선행연구를 통하여 이론적 배경을 살펴본 후, 3d 온라인 게임 '오버워치'의 영웅 캐릭터들의 포즈(pose)를 수집하고 직접 라인을 그려 포즈를 분석하였다. 그 결과 단순하고 명확한 동선을 가진 캐릭터들의 포즈가 캐릭터의 특징을 잘 표현하고 전달이 명확한 것을 알 수 있었다. 이 연구를 통하여 게임 애니메이션 제작에서 캐릭터 포즈의 표현 기법에 대하여 고찰하고자 하였으며, 실무에서 게임애니메이터들에게 중요한 참고자료가 되기를 기대한다.

• 디지털융복합연구
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• 제15권12호
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• pp.461-468
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• 2017

'미녀와 야수'는 1740년 소설로 탄생해 2017년 뮤지컬 실사 영화로 현재까지 전해 내려왔다. 본 논문은 시대 배경으로 '미녀와 야수'를 분석해 봄으로써 하나의 이야기가 277년 동안 어떤 콘텐츠로 파생되고 확장됐는지를 이야기 변화와 함께 알아보는 것이 목적이다. 본 논문은 민담, 설화를 다 담기에 한계가 있어 '미녀와 야수' 이름으로 알려지고 기록된 유명한 콘텐츠들로 한정한다. '미녀와 야수'는 소설, 동화, 영화, 드라마, 애니메이션, 뮤지컬, 필름 오페라의 7가지 콘텐츠로 확장됐다. 18세기 소설로 탄생해 아동교육을 위해 동화로 만들어지고 장 콕토 감독에 의해 영화로 제작되었다. 산업혁명과 과학의 발달로 애니메이션, 드라마, 뮤지컬 콘텐츠로 파생된 '미녀와 야수'는 음악 산업의 발달과 필립 글래스의 새로운 시도로 필름 오페라로 만들어진다. '미녀와 야수'는 컴퓨터 기술의 발달과 전 세계 리메이크 현상으로 다양한 콘텐츠로 끊임없이 재탄생 되고 있다. 이후로도 더 다양한 '미녀와 야수' 분석 연구가 진행되길 기대해 보며 본 연구 자료가 다른 연구 자료들에 참고 자료로 기여될 수 있길 기대해 본다.

• Tuberculosis and Respiratory Diseases
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• 제83권4호
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• pp.289-294
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• 2020

Background: Line probe assay (LPA) is standard diagnostic tool to detect multidrug resistant tuberculosis. Non-interpretable (NI) results in LPA (complete missing or light wild-type 3 and 8 bands with no mutation band in rpoB gene region) poses a diagnostic challenge. Methods: Sputum samples obtained between October 2016 and July 2017 at the Intermediate Reference Laboratory, All India Institute of Medical Sciences Hospital, New Delhi, India were screened. Smear-positive and smear-negative culture-positive specimens were subjected to LPA Genotype MTBDRplus Ver 2.0. Smear-negative with culture-negative and culture contamination were excluded. LPA NI samples were subjected to phenotypic drug susceptibility testing (pDST) using MGIT-960 and sequencing. Results: A total of 1,614 sputum specimens were screened and 1,340 were included for the study (smear-positive [n=1,188] and smear-negative culture-positive [n=152]). LPA demonstrated 1,306 (97.5%) valid results with TUB (Mycobacterium tuberculosis) band, 24 (1.8%) NI, three (0.2%) valid results without TUB band, and seven (0.5%) invalid results. Among the NI results, 22 isolates (91.7%) were found to be rifampicin (RIF) resistant and two (8.3%) were RIF sensitive in the pDST. Sequencing revealed that rpoB mutations were noted in all 22 cases with RIF resistance, whereas the remaining two cases had wild-type strains. Of the 22 cases with rpoB mutations, the most frequent mutation was S531W (n=10, 45.5%), followed by S531F (n=6, 27.2%), L530P (n=2, 9.1%), A532V (n=2, 9.1%), and L533P (n=2, 9.1%). Conclusion: The present study showed that the results of the Genotype MTBDRplus assay were NI in a small proportion of isolates. pDST and rpoB sequencing were useful in elucidating the cause and clinical meaning of the NI results.

• Nutrition Research and Practice
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• 제12권3호
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• pp.258-264
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• 2018

BACKGROUND/OBJECTIVES: Diet quality scores or indices, based on dietary guidelines, are used to summarize dietary intake into a single numeric variable. The aim of this study was to examine the association between the modified diet quality index for Koreans (DQI-K) and mortality among Health Examinees-Gem (HEXA-G) study participants. SUBJECTS/METHODS: The DQI-K was modified from the original diet quality index. A total of 134,547 participants (45,207 men and 89,340 women) from the HEXA-G study (2004 and 2013) were included. The DQI-K is based on eight components: 1) daily protein intake, 2) percent of energy from fat, 3) percent of energy from saturated fat, 4) daily cholesterol intake, 5) daily whole-grain intake, 6) daily fruit intake, 7) daily vegetable intake, and 8) daily sodium intake. The association between all-cause mortality and the DQI-K was examined using Cox proportional hazard regression models. Hazard ratios and confidence intervals were estimated after adjusting for age, gender, income, smoking status, alcohol drinking, body mass index, and total energy intake. RESULTS: The total DQI-K score was calculated by summing the scores of the eight components (range 0-9). In the multivariable adjusted models, with good diet quality (score 0-4) as a reference, poor diet quality (score 5-9) was associated with an increased risk of all-cause mortality (hazard ratios = 1.23, 95% confidence intervals = 1.06-1.43). Moreover, a one-unit increase in DQI-K score resulted in a 6% higher mortality risk. CONCLUSIONS: A poor diet quality DQI-K score was associated with an increased risk of mortality. The DQI-K in the present study may be used to assess the diet quality of Korean adults.

• Journal of Chest Surgery
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• 제47권3호
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• pp.233-239
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• 2014

Background: As hypertrophied myocardium predisposes the patient to decreased tolerance to ischemia and increased reperfusion injury, myocardial protection is of utmost importance in patients undergoing aortic valve replacement (AVR) for severe aortic valve stenosis (AS). Methods: Consecutive 314 patients (mean age, $62.5{\pm}10.8$ years; 143 females) with severe AS undergoing isolated AVR were included. Postoperative myocardial injury (PMI) was defined as 1) maximum postoperative creatinine kinase isoenzyme MB or troponin-I levels ${\geq}10$ times of reference, 2) postoperative low cardiac output syndrome or episodes of ventricular arrhythmia, or 3) left ventricular ejection fraction of less than 55% and decrease in left ventricle (LV) ejection fraction of more than 20% of the baseline value. Results: There were 90 patients (28.7%) who developed PMI. There were five cases of early death (1.6%), all of whom had PMI. On multivariable analysis, the use of histidine-tryptophan-ketoglutarate (HTK) solution instead of blood cardioplegia (odds ratio [OR], 3.06; 95% confidence interval [CI], 1.63 to 5.77; p=0.001), greater LV mass (OR, 1.04; 95% CI, 1.01 to 1.07; p=0.007), and increased cardiac ischemic time (OR, 1.13; 95% CI, 1.05 to 1.22; p<0.001) were independent predictors for PMI. Patients who had PMI showed significantly inferior long-term survival than those without PMI (p=0.049). Conclusion: PMI occurred in a considerable proportion of patients undergoing AVR for severe AS and was associated with poor long-term survival. HTK cardioplegia, higher LV mass, and longer cardiac ischemic duration were suggested as predictors of myocardial injury.

• Nutrition Research and Practice
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• 제10권1호
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• pp.115-124
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• 2016

BACKGROUND/OBJECTIVES: This is the first study to identify common genetic factors associated with the basal metabolic rate (BMR) and body mass index (BMI) in obese Korean women including overweight. This will be a basic study for future research of obese gene-BMR interaction. SUBJECTS/METHODS: The experimental design was 2 by 2 with variables of BMR and BMI. A genome-wide association study (GWAS) of single nucleotide polymorphisms (SNPs) was conducted in the overweight and obesity (BMI > $23kg/m^2$) compared to the normality, and in women with low BMR (< 1426.3 kcal/day) compared to high BMR. A total of 140 SNPs reached formal genome-wide statistical significance in this study (P < $1{\times}10^{-4}$). Surveys to estimate energy intake using 24-h recall method for three days and questionnaires for family history, a medical examination, and physical activities were conducted. RESULTS: We found that two NRG3 gene SNPs in the 10q23.1 chromosomal region were highly associated with BMR (rs10786764; $P=8.0{\times}10^{-7}$, rs1040675; $2.3{\times}10^{-6}$) and BMI (rs10786764; $P=2.5{\times}10^{-5}$, rs10786764; $6.57{\times}10^{-5}$). The other genes related to BMI (HSD52, TMA16, MARCH1, NRG1, NRXN3, and STK4) yielded P < $10{\times}10^{-4}$. Five new loci associated with BMR and BMI, including NRG3, OR8U8, BCL2L2-PABPN1, PABPN1, and SLC22A17 were identified in obese Korean women (P < $1{\times}10^{-4}$). In the questionnaire investigation, significant differences were found in the number of starvation periods per week, family history of stomach cancer, coffee intake, and trial of weight control in each group. CONCLUSION: We discovered several common BMR- and BMI-related genes using GWAS. Although most of these newly established loci were not previously associated with obesity, they may provide new insights into body weight regulation. Our findings of five common genes associated with BMR and BMI in Koreans will serve as a reference for replication and validation of future studies on the metabolic rate.

• Asian Pacific Journal of Cancer Prevention
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• 제17권6호
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• pp.2941-2946
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• 2016

Background: The limitations of total serum PSA values remain problematic, especially after an initial negative prostate biopsy. In this prospective study of Chilean men with a continued suspicion of prostate cancer due to a persistently elevated total serum PSA, abnormal digital rectal examination and initial negative prostate biopsy were compared with the use of the on-line Chun nomagram, detection of primary malignant circulating prostate cells (CPCs) and free percent PSA to predict a positive second prostate biopsy. We hypothesized that men negative for circulating prostate cells have a small risk of clinically significant prostate cancer and thus may be conservatively observed. Men positive for circulating prostate cells should undergo biopsy to confirm prostate cancer. Materials and Methods: Consecutive men with a continued suspicion of prostate cancer underwent 12 core TRUS prostate biopsy; age, total serum PSA and percentage free PSA and Chun nomagram scores were registered. Immediately before biopsy an 8ml blood simple was taken to detect primary mCPCs. Mononuclear cells were obtained by differential gel centrifugation and identified using double immunostaining with anti-PSA and anti-P504S. Biopsies were classifed as cancer/no-cancer, mCPC detecton test as negative/positive and the total number of cells/8ml registered. Areas under the curve (AUC) for percentage free PSA, Chun score and CPCs were calculated and compared. Diagnostic yields were calculated with reference to the number of possible biopsies that could be avoided and the number of clinically significant cancers that would be missed. Results: A total of 164 men underwent a second biopsy; 41 (25%) had cancer; the AUCs were 0.65 for free PSA, 0.76 for the Chun score and 0.87 for CPC detection, the last having a significantly superior prediction value (p=0.01). Using cut off values of free PSA <10%, Chun score >50% and ${\geq}1$ CPC detected, CPC detection had a higher diagnostic yield. Some 4/41 cancers complied with the criteria for active surveillance, free PSA and the Chun score missed a higher number of significant cancers when compared with CPC detection. Conclusions: Primary CPC detection outperformed the use of free PSA and the Chun nomagram in predicting clinically significant prostate cancer at repeat prostate biopsy.

• Journal of Korean Medical Science
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• 제33권52호
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• pp.347.1-347.11
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• 2018

Background: Smartphone addiction has recently been highlighted as a major health issue among adolescents. In this study, we assessed the degree of agreement between adolescents' and parents' ratings of adolescents' smartphone addiction. Additionally, we evaluated the psychosocial factors associated with adolescents' and parents' ratings of adolescents' smartphone addiction. Methods: In total, 158 adolescents aged 12-19 years and their parents participated in this study. The adolescents completed the Smartphone Addiction Scale (SAS) and the Isolated Peer Relationship Inventory (IPRI). Their parents also completed the SAS (about their adolescents), SAS-Short Version (SAS-SV; about themselves), Generalized Anxiety Disorder-7 (GAD-7), and Patient Health Questionnaire-9 (PHQ-9). We used the paired t-test, McNemar test, and Pearson's correlation analyses. Results: Percentage of risk users was higher in parents' ratings of adolescents' smartphone addiction than ratings of adolescents themselves. There was disagreement between the SAS and SAS-parent report total scores and subscale scores on positive anticipation, withdrawal, and cyberspace-oriented relationship. SAS scores were positively associated with average minutes of weekday/holiday smartphone use and scores on the IPRI and father's GAD-7 and PHQ-9 scores. Additionally, SAS-parent report scores showed positive associations with average minutes of weekday/holiday smartphone use and each parent's SAS-SV, GAD-7, and PHQ-9 scores. Conclusion: The results suggest that clinicians need to consider both adolescents' and parents' reports when assessing adolescents' smartphone addiction, and be aware of the possibility of under- or overestimation. Our results cannot only be a reference in assessing adolescents' smartphone addiction, but also provide inspiration for future studies.