• Phonetics and Speech Sciences
• /
• v.7 no.3
• /
• pp.45-53
• /
• 2015

The current study investigated CVCC syllables in spontaneous American English speech to find out whether such syllables are produced as phonological units with a string of segments, showing a hierarchical structure. Transcribed data from the Buckeye Speech Corpus was used for the analysis in this study. The result of the current study showed that the constituents within a CVCC syllable as a phonological unit may have phonetic variations (namely, the final coda may undergo deletion). First, voiceless alveolar stops were the most frequently deleted when they occurred as the second final coda consonants of a CVCC syllable; this deletion may be an intermediate process on the way from the abstract form CVCC (with the rime VCC) to the actual pronunciation CVC (with the rime VC), a production strategy employed by some individual speakers. Second, in the internal structure of the rime, the proportion of deletion of the final coda consonant depended on the frequency of the word rather than on the position of postvocalic consonants on the sonority hierarchy. Finally, the segment following the consonant cluster proved to have an effect on the reduction of that cluster; more precisely, the following contrast was observed between obstruents and non-obstruents, reflecting the effect of sonority: when the segment following the consonant cluster was an obstruent, the proportion of deletion of the final coda consonant was increased. Among these results, the effect of word frequency played a critical role for promoting the deletion of the second coda consonant for clusters in CVCC syllables in spontaneous speech. The current study implies that the structure of syllables as phonological units can vary depending on individual speakers' lexical representation.

• Journal of the Korea Convergence Society
• /
• v.12 no.8
• /
• pp.309-315
• /
• 2021

Pycnogenol extracted from pine bark is a component with great antibacterial activity and antioxidant effect. It is applied as a natural anti-inflammatory agent with various medical effects including anti-inflammatory effects, regulation of blood pressure, regulation of the immune system, and inhibition of cancer cell growth. However, research related to cosmetics is limited. Therefore, in this study, the effect of Pycnogenol on the skin was studied through a clinical approach. Changes in skin condition were observed after using cosmetics with Pycnogenol and without Pycnogenol for 6 weeks for 10 clinicians in each group. We observed the effect of pore reduction, wrinkle reduction around eyes, a decrease of the number and angle of loose pores, and reduction of pigmentation. Therefore, cosmetics containing Pycnogenol have the effect of improving skin problems of aging skin.

• Journal of Digital Convergence
• /
• v.19 no.7
• /
• pp.95-111
• /
• 2021

Despite the innovation of AI and Big Data, theoretical research bout the effect of AI and Big Data on market competition is still in early stages; therefore, this paper analyzes the effect of AI, Big Data, and data sharing on an entry firm by using game theory. In detail, the firms' business environments are divided into internal and external ones. Then, AI algorithms are divided into algorithms for (1) customer marketing, (2) cost reduction without automation, and (3) cost reduction with automation. Big Data is also divided into external and internal data. this study shows that the sharing of external data does not affect the incumbent firm's algorithms for consumer marketing while lessening the entry firm's entry barrier. Improving the incumbent firm's algorithms for cost reduction (with and without automation) and external data can be an entry barrier for the entry firm. These findings can be helpful (1) to analyze the effect of AI, Big Data, and data sharing on market structure, market competition, and firm behaviors and (2) to design policy for AI and Big Data.

• Journal of Periodontal and Implant Science
• /
• v.32 no.2
• /
• pp.415-428
• /
• 2002

Periodontal disease is a complex infectious disease caused by bacteria in the oral mucosa, which results in gingival inflammation, breakdown of periodontal tissues, bone resorption, and finally tooth loss. Mechanical plaque control methods-scaling and root planing are effective methods to stop the progression of such periodontal disease. It was reported that subantimicrobial dose of doxycycline(SDD) regimen could improve clinical conditions of periodontal tissues without causing the overgrowth of opportunistic organisms that was a typical antibiotic side effect. Therefore pharmacological therapy, used in conjunction with mechanical therapy could be considered a useful treatment modality in the treatment of chronic periodontal disease. In this study, 30 patients diagnosed as moderate to advanced chronic periodontitis were divided into 2 groups. In this double-blind, placebo-controlled study, the patients were administered 20mg doxycycline capsule or placebo capsule b.i.d. for 4months, after scaling and root planing. Clinical parameters-bleeding on probing, pocket depth and clinical attachment level were compared and evaluated between these groups at periods of first visit, 1 month, 2 months, 3 months, 4 months. The results were as follows ; 1. In case of moderate periodontitis, pocket depth showed significant reduction after treatment in both the control & experiment groups, when compared with the baseline values(p<0.01), but in case of advanced periodontitis, only the experiment group showed significant reduction after treatment when compared with the baseline values(p<0.05). Statistically significant reduction in pocket depth was observed in the experiment group compared to the control group(p<0.05). 2. In case of moderate periodontitis, clinical attachment level showed significant reduction after treatment in both the control & experiment groups, when compared with the baseline values(p<0.01), but in case of advanced periodontitis, only the experiment group showed significant reduction after treatment when compared with the baseline values(p<0.05). Statistically significant reduction in clinical attachment level was observed in the experiment group compared to the control group(p<0.05). 3. Bleeding on probing improved after treatment in both the groups. In case of moderate periodontitis, the experiment group showed statistically significant reduction of bleeding on probing when compared with the control group at 1 and 4 months after treatment(p<0.05). In case of advanced periodontitis, treatment resulted in statistically significant reduction of bleeding on probing in both the groups(p<0.05). These results indicate that the use of subantimicrobial dose of doxycycline is a useful supplement to mechanical treatment for periodontal patients in ameliorating the clinical parameters such as periodontal pocket, attachment level, and bleeding on probing.

• The Korean Journal of Mycology
• /
• v.21 no.1
• /
• pp.23-27
• /
• 1993

Ion effects on $11{\alpha}-hydroxylation$ of progesterone and $5{\alpha}-reduction\;of\;11{\alpha}-hydroxyprogesterone$ by Rhizopus nigricans were investigated. Metal ions such as $Cu^{2+},\;Cd^{2+},\;Co^{2+},\;Mn^{2+},\;Zn^{2+},\;Fe^{2+},\;Mg^{2+},\;Fe^{3+}\;and\;Na^+$ reduced the $11{\alpha}-hydroxylation$ activity, while $K^+$ stimulated the same reaction. Enzyme activity for the $5{\alpha}-reduction$ of $11{\alpha}-hydroxyprogesterone$ was increased in the presence of $Fe^{2+},\;Mn^{2+},\;Mg^{2+},\;Co^{2+},\;Zn^{2+},\;Fe^{3+},\;K^+\;and\;Na^+$, whereas it was decreased in the presence of $Cd^{2+}\;and\;Cu^{2+}$. Potassium ion of $10^{-3}\;M\;$ of concentration was found to be effective for the promotion of $11{\alpha}-hydroxylation$. On the other hand, cadmium ion of $10^{-4}\;M$ was proved to suppress the $5{\alpha}-reduction$ reaction. Progesterone is reported to be transformed into $11{\alpha}-hydroxyprogesterone$ which, in turn, is converted further into $11{\alpha}-hydroxy-allopregnane-3$, 20-dione by R. nigricans. From this point of view, the highest yield of $11{\alpha}-hydroxyprogesterone$ could be obtained when potassium ion of $10^{-3}\;M$ was given initially followed by addition of cadmium ion of $10^{-4}\;M$ to limit conversion of 11{\alpha}-hydroxyprogesterone into $11{\alpha}-hydroxy-allopregnane-\;3$, 20-dione.

• Clean Technology
• /
• v.24 no.2
• /
• pp.135-145
• /
• 2018

There are various activities for reduction of the greenhouse gasses (GHG) emission around the world. The countries agreed to submit their's individual plans to the United Nations and have operated programs related to the Climate Change, in addition, the enterprises have spontaneously been developed individual calculation methodologies of GHG emission. This paper aims at examining methods for calculating the effect of the reduction of environmental impact, being divided into three categories; international standard, country, enterprise. The reduction effects of environmental impact were compared by applying an existing product of the vehicle undercover and the uni-materialized product and being selected six calculation methods of environmental footprint. There are significant differences according to the evaluation methods of product environmental footprint (PEF) reduction. Main factors of differences are a gap in system boundary, a scope of data collection and the replacement amount standard of existing products. Stakeholders are unreliable in the results of PEF reduction because of the differences in results by each methodology. Therefore, it is necessary to disclose in detail the methodologies of calculating the PEF reduction that relevant people can easily understand, also to enable comparisons of the reduction results by developing the standardization of evaluation methods of PEF in the long term.

• Fashion & Textile Research Journal
• /
• v.9 no.1
• /
• pp.119-123
• /
• 2007

Dyeing properties of soybean fabrics on gromwell colorants were studied for the effect of dyeing conditions, such as colorants concentration, temperature, time and pH on the dye uptake and effect of mordants on color change, dye uptake and various colorfastness. Antimicrobial activity of soybean fabrics dyed and sim-mordanted with gromwell colorants was examined by shake flask method. Gromwell colorants showed considerably affinity to soybean fabric and its isotherm adsorption curve was Freundlich type. Therefore, it is considered that hydrogen bonding and Van der Waals force were involved in the adsorption of gromwell colorants to soybean fabric. Soybean fabrics showed R color on Al, Cu and Sn mordant, RP color on Cr and Fe mordant, but soybean fabrics showed low dye uptake depending on mordanting treatment. Light colorfastness was increased for Cr and Fe mordants. Staphylococcus aureus reduction rates were above 90% for Cr and Cu mordanted soybean fabrics, and the others were poor. Klebsiella pneumoniae reduction rates soybean fabrics did not show reduction rate hardly.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
• /
• 2007.11a
• /
• pp.253-257
• /
• 2007

In case of the hydraulic turbine dynamo room at Dam, due to its big volume and reflexible finishing material, since the noise of electricity-generation is amplifying, it influences the difficulty of mutual communication among the workers, also it is causing both mental and physical damages to those workers in the neighboring office. Accordingly, after presentation of the optimized renovation model of the hydraulic turbine dynamo room using the acoustic simulation, this Research has compared and evaluated them using the auralizational technique between the present condition of "before improvement" and the acoustic condition of "after improvement". As the result of psycho-acoustics experiment, as the acoustic conditions at both "before & after Improvement" were apparently compared, it appeared that there is a considerable amount of noise-reduction effect at psycho-acoustics. It is considered that such material could be utilized as the valuable data hereafter for the time when any construction and renovation of the hydraulic turbine dynamo room and other similar workshop.

• Korean Journal of Pharmacognosy
• /
• v.30 no.2
• /
• pp.151-157
• /
• 1999

In order to find less toxic antiherpetic agents, the effect of natural quercetin on the plaque formation of herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) was studied in vitro in cell culture monolayers employing the technique of viral plaque reduction assay. Quercetin caused a concentration-dependent reduction in the plaque formation of herpesviruses. It also exhibited more potent antiherpetic activity on HSV-1 with effective concentration $(EC_{50})$ of $18.7\;{\mu}g/ml$ than on HSV-2 with $EC_{50}$ of $24.5\;{\mu}g/ml$. The combined antiherpetic effects of quercetin with nucleoside antiherpetic agents, acyclovir and vidarabine, were examined on the multiplication of these two strains of herpesviruses in Vero cells by the combination assay. The results of combination assay were evaluated by the combination index (CI) that was calculated by the multiple drug effect analysis. The combinations of quercetin with acyclovir on HSV-1 and HSV-2 showed more potent synergism with CI values of $0.19{\sim}0.89$ for 50%, 70%, 90% effective levels than those with vidarabine with CI values of $0.43{\sim}1.46$.

• Communications for Statistical Applications and Methods
• /
• v.19 no.1
• /
• pp.107-115
• /
• 2012

Yoo and Cook (2007) developed an optimal sufficient dimension reduction methodology for the conditional mean in multivariate regression and it is known that their method is asymptotically optimal and its test statistic has a chi-squared distribution asymptotically under the null hypothesis. To check the effect of dimension used in estimation on regression coefficients and the explanatory power of the conditional mean model in multivariate regression, we applied their method to several simulated data sets with various dimensions. A small simulation study showed that it is quite helpful to search for an appropriate dimension for a given data set if we use the asymptotic test for the dimension as well as results from the estimation with several dimensions simultaneously.