• Journal of Chest Surgery
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• v.29 no.10
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• pp.1076-1080
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• 1996

The results about the myocardial protection of recta of the nitric oxide precursor L-arginine upon reperrusion injury after ischemia are diverse. These diversities may be model dependent. Experiments were designed and performed to investigate myocardial protection effects according to the concentration of L-arginine. The Isolated rat hearts were subjected in a 30 minutes oi normothermic ischemia and reperfused for 30 minutes with reperfusate containing 0, 1, 2, 3, 4 moil L-arginine. After 30 minutes of reperfusion, group with 1 and 2 mM/L L-arginine showed a trend of better recovery in left ventricular systolic function(left ventricular developed pressure, positive maximum dpfdt), diastolic function(negative maximum dpfdt) and coronary flow compared to control group(reperfusate no L-arginine). Recovery was impaired with a higher concentration, and at 4 moil L-arginine r covery was worse than control(p (0, 05). These results suggest that optimal concentration of L-arginine Is Important or the recovery of myocardial and endothelial function after ischemia and reperfusion.

• The Journal of Korean Obstetrics and Gynecology
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• v.19 no.4
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• pp.216-224
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• 2006

Purpose : This study was conducted to investigate the effect of Mokhyangsaenghwa-tang beverage on postpartum recovery and lactation. One theory of oriental medical treatment for postpartum care is focused on increasing vitality and building up blood. Saengwha-tang are representative remedies for these respective principle of treatment. This experiment was carried out to evaluate the clinical effects of Mokhyangsaenghwa-tang on blood components, Body weight, BMI and prolactin level in postpartum. Methods : 65 postpartum women applied for this study, and 30 of them were included in this study. They were divided two groups. The experimental group were treated by Mokhyangsaenghwa-tang beverage, the control group were treated by citron beverage during 40 days. Then we observed the changes of the body weight, BMI, complete blood cell count, liver function test, renal function test, level of serum prolactin, Urine analysis and general conditon Questionnaire among baseline(before treatment), 1st phase(after 20 days treatment) and 2nd phase(after 40 days treatment). Results : After taking Mokhyangsaenghwa-tang beverage, body weight, body water, edema index, prolactin ana general condtion became better, but they were not statistically significant. Conclusion : This study shows that Mokhyangsaenghwa-tang can improve postpartum recovery, but more research is needed.

• The Journal of Korean Obstetrics and Gynecology
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• v.18 no.1
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• pp.111-127
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• 2005

Objective : This study was conducted to investigate the effect of Mokhyangsaenghwa-tang (MS) and Mokhyangsaenghwa-tang plus Cervi Pantotrichum Cornu (MS-C) on postpartum recovery and lactation. Materials and Methods : We used 18-week pregnant Spraque Dawley rats and administered the decoctions of MS and MS-C to rats once a day for 4 days or 8 days. Then we observed changes in the body weight of pup rats and complete blood cell count, liver function test, renal function test, mammary gland tissue, level of serum prolactin, ${\beta}-casein$ and WAP of postpartum rats. Result : A significant increase in body weight was observed in MS-C treated pup rats compared with in MS treated group. The levels of WBC and platelet from MS group and MS-C group were decreased compared with the control group. The levels of RBC, hemoglobin and hematocrit from MS group and MS-C group showed statistically significant increases compared with the control group. The levels of protein, albumin from MS group and MS-C group were increased compared with the control group. The levels of BUN, creatinine from MS group and MS-C group did not show statistically significant changes compared with the control group. The mammary gland tissues from MS group and MS-C group showed increased angiogenesis. The levels of serum prolactin from MS group and MS-C group were increased compared with the control group. The expression of ${\beta}-casein$ and WAP genes from postpartum rats treated with MS and MS-C was increased. Conclusion : This study shows that MS and MS-C improved postpartum recovery and lactation in rats.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.34 no.9
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• pp.11-19
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• 2006

Design program was developed to determine the external shape of the supersonic axisymmetric inlet by combining conical flow solver and approximation technique of conical shock with gradient-based optimization algorithm. Inlet designs were carried out under various operation conditions through optimization with respectively two object functions which consist of pressure recovery and cowl drag and with constraints about shock position, cowl shape, and minimum throat area. New object function consisting of pressure recovery and drag of the external cowl was proposed and the optimized shapes from new object function were compared to the ones from the old object function which maximize only the pressure recovery. Through computations of inviscid and turbulent flow, was tested performance of the design program and performance estimated in design program agreed well with computation results for inlets designed under various flight conditions.

• Journal of Animal Reproduction and Biotechnology
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• v.34 no.3
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• pp.166-172
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• 2019

Heart rate is a relatively simple and non-invasive method that is used as an important physiological indicator in many studies and has a close relationship with heart structure and function, cardiovascular disease and sudden cardiac death. In general, appropriately low heart rate during resting means effective heart function and cardiovascular fitness; heart rate at recovery is an important indicator of health and disease condition. We found a beagle dog (Dog_1) with a high heart rate in the previous preliminary experiment. Therefore, purpose of this study was to compare the heart rate response of the Dog_1 with the control group during 12 weeks of interval exercise, to evaluate the structural and functional abnormalities of the heart and to verify the applicability of exercise program. Heart rate was checked during 12 weeks of interval exercise, and after the exercise was over, imaging examination and hematological and serum biochemistry were performed. As a result, Dog_1 (165.6 ± 1.5) showed significantly higher heart rate in low intensity session of interval exercise than control group (133.3 ± 0.5, p < 0.01). In addition, Dog_1 (181.2 ± 1.4) showed significantly higher heart rate than control group (155.1 ± 0.9) in high intensity session (p < 0.01). The heart rate (30 sec, 60 sec) during recovery state was higher in Dog_1 (30 sec: 156.8 ± 4.0, 60 sec: 166.8 ± 5.8) than in the control group (30 sec: 111.2 ± 2.5, 60 sec: 104.0 ± 5.1, p < 0.01). The results of the imaging examination of Dog_1 with high heart rate confirmed that the heart had no functional and structural abnormalities. All beagles with the interval exercise program did not show maladjustment, and in the hematological and serum biochemistry results, all the parameter were within the reference range. If the interval exercise program of this study is used in the future, it is expected to be used as an important basic data to achieve the purpose of health, welfare, and physical fitness improvement of dogs.

• The Journal of Korean Medicine
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• v.43 no.3
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• pp.164-180
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• 2022

Objectives: The purpose of this study was to evaluate the effects of shenfu injection on myocardial protective effects after mitral valve replacement surgery. Methods: We searched four international databases (PUBMED, Embase, Web of Science and CNKI) and three domestic electronic databases (OASIS, RISS and NDSL) for relevant studies. We used following keywords 'shenfu', 'valve replacement', 'mitral valve' at PUBMED, Embase and Web of Science; '二尖瓣', '参附注射液', '瓣膜' at CNKI and '이첨판', '판막', '삼부' at domestic databases. The search range included randomized controlled trials. When appropriate, meta-analyses were performed. Results: Seven randomized controlled trials were selected. All studies used Shenfu injection after mitral valve replacement surgery. We analyzed myocardial damage, cardiac function, patients' recovery rate, with various evaluation indicators. We also used meta-analysis for CK-MB, cTnI, MDA and voluntary recovery of heartbeat. CK-MB was analyzed in two subgroups: 8 hours and 24 hours after surgery. Std was -2.34(95% CI -4.10, -0.58) for 8 hours and -1.95(95% CI -4.79 to 0.88) for 24 hours. 8 hours showed statistically significant difference. cTnI appeared significant decrease with Std of -2.13(95% CI -2.60, -1.66). MDA showed significant decrease with Std of -0.95(95% CI -1.43 to -0.47). Voluntary recovery of heartbeat significantly increased with the odd ratio of 4.34(95% CI 1.76, 10.70). Conclusions: We suggest that Shenfu injection after Mitral valve replacement surgery may have significant myocardial protective effects in terms of reducing myocardial damages, reactive oxygen species, increasing cardiac function and patients' recovery after surgery. However, the evidence is limited, further research is required.

• The Korean Journal of Nuclear Medicine Technology
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• v.22 no.1
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• pp.43-45
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• 2018

Purpose In this study, we evaluated image by applying with and without point spread function algorithm(PSF) according to reconstruction type. Materials and Methods Biograph mMR (Siemens, Germany) was used as PET/MR scanner. For phantom study, we used NEMA IEC Body phantom maintaining radioactivity ratio (hotsphere:background = 8:1). To evaluate phantom image quality, percent contrast recovery and signal to noise ratio (SNR) were used by drawing ROI to 4 spheres. In clinical study, the 20 patients who underwent simultaneous PET/MR was selected and set the ROI at liver. we evaluated images as SNR. Results In the phantom results, The percent contrast recovery applying PSF algoritm was high 5 % compared to without PSF algoritm and SNR was also high 11 %. In the clinical study result, we confirmed that The SNR applying PSF algoritm was high 5 % compared to without PSF algoritm. Conclusion We need to simulate a lot of phantom study and clinical analysis to improve image quality for PET/MRI.

• Korean Journal of Applied Biomechanics
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• v.22 no.2
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• pp.209-217
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• 2012

The purpose of this study was to develop a turn-type treatment program which applies the principle of spotting and a roll-type treatment program that induces off-vertical axis. 29 collegiate students volunteered for this study. 12-week treatment programs were applied to both 15 students for turn-type treatment group and 14 students for roll-type treatment group. As an analytic tool, eye camera was employed to verify the treatment programs for a stimulus upon a turn, recovery after a stimulus upon a turn, and nystagmus that affects a vestibular system. Two-way ANOVA with repeated measures was applied to see the significant differences between the treatment groups, and between the test periods. For Post-Hoc Test, paired t-test was used to within the group and independent t-test was used to between the groups. The results indicated that roll-type treatment training has maximized a stimulus on nystagmyus during the stimulus by a roll. Turn-type treatment training has maximized a stimulus on nystagmyus right after a stimulus by a roll and significantly decreased the intensity of nystagmyus during the recovery. Both turn and roll type treatments have reduced the recovery time which from nystagmyus to a normal status. Roll-type treatment has showed a much shorter recovery time for nystagmyus than the roll-type treatment has. Based on the results of treatment programs developed in this study, we expect the treatment programs can be applied to treat dizziness and to improve the function of vestibular system as a rehabilitation tool.

• Journal of Korean Neurosurgical Society
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• v.46 no.2
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• pp.109-115
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• 2009

Objective: The decision to adopt a conservative or surgical modality for a relatively small volume of spontaneous intracerebral hemorrhage (SICH) is difficult and often controversial, especially when consciousness is tolerable. The authors examined the results of stereotactic-guided evacuation of SICH for relatively small volumes with respect to functional outcome. Methods: This prospective study was performed on 387 patients with SICH who underwent stereotactic-guided evacuation (n = 204, group A) or conservative treatment (n = 183, group B) during the past 8 years. The primary end-point was recovery of functional status, which was estimated using the Modified Barthel Index (MBI) and the modified Rankin Scale (mRS). Results: All patients had a Glasgow coma scale (GCS) score of $\geq$ 13 and unilateral hemiparesis of less than motor power grade 3. Group demographic characteristics and initial neurological statuses were similar. In all cases, the volume of SICH involved was < 30 cm$^3$ and location was limited to basal ganglia and thalamus. At 6-month follow-ups, MBI was 90.9 in group A and 62.4 in group B (p < 005), and MRS was 1.2 in group A and 3.0 in group B (p < 0.05). Better motor function and stereotactic-guided evacuation had a significant effect on a functional recovery in regression analyses. Conclusion: Even in patients with a small volume of SICH, stereotactic-guided evacuation improved functional recovery in activities in daily life than conservative treatment did.

• Convergence Security Journal
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• v.3 no.3
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• pp.51-57
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• 2003

The Real-time DBMS must provide the keeping, fabrication and control function which the data where the user requsets for processing inside the hour when it is restricted, it is quick most and safely[3]. In order lide this to take chare of the real-time control and fabrication function, details recording (log) of the control processing is very important in accomplished transactions from inside the Real-time DBMS. In this proposal, it sees recording which is like this in base and it proposes the new recovery function for transactions log. This recovery technique which it sees used the concept of the LIFO (Last-In-First-Out) method with basic. The proposed technique will becomes the technique which it will be able and to record to process efficiently with a same attribute and the continuous transactions log.