• Clinical and Experimental Reproductive Medicine
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• 제50권3호
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• pp.177-184
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• 2023

Objective: Reconstructed oocytes after polar body genome transfer constitute a potential therapeutic option for patients with a history of embryo fragmentation and advanced maternal age. However, the rescue of genetic material from the first polar body (PB1) through introduction into the donor cytoplasm is not yet ready for clinical application. Methods: Eighty-five oocytes were obtained following in vitro maturation (IVM) and divided into two groups: PB1 nuclear transfer (PB1NT; n=54) and control (n=31). Following enucleation and PB1 genomic transfer, PB1 fusion was assessed. Subsequently, all fused oocytes underwent intracytoplasmic sperm injection (ICSI) and were cultured in an incubator under a time-lapse monitoring system to evaluate fertilization, embryonic morphokinetic parameters, and cleavage patterns. Results: Following enucleation and fusion, 77.14% of oocytes survived, and 92.59% of polar bodies (PBs) fused. However, the normal fertilization rate was lower in the PB1NT group than in the control group (56.41% vs. 92%, p=0.002). No significant differences were observed in embryo kinetics between the groups, but a significant difference was detected in embryo developmental arrest after the four-cell stage, along with abnormal cleavage division in the PB1NT group. This was followed by significant between-group differences in the implantation potential rate and euploidy status. Most embryos in the PB1NT group had at least one abnormal cleavage division (93.3%, p=0.001). Conclusion: Fresh PB1NT oocytes successfully produced normal zygotes following PB fusion and ICSI in IVM oocytes. However, this was accompanied by low efficiency in developing into cleavage embryos, along with an increase in abnormal cleavage patterns.

• 트랜스-
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• 제11권
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• pp.65-95
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• 2021

서양 예술에서 이성적이고 고전적인 순정미(純精美)에 반발하기 위한 돌파구의 일종으로 종종 등장하였던 그로테스크(Grotesque)는 현대 예술에서 자주 목격된다. 그리고 그로테스크는 추(醜)라는 개념과 더불어 문화, 예술 그리고 사회 전반적인 층위에서 무한히 확장된 형태로 나타난다. 특히 신체의 탈형식화와 탈정형화를 통한 변용된 신체 이미지는 정형화된 미를 탈피하고자하는 강력한 거부로 해석된다. 본 연구는 디미트리스 파파이오아누의 작품에 나타난 신체의 변형과 왜곡, 그리고 결합을 통해 재생산된 신체가 그로테스크 범주 안에서 어떻게 해석될 수 있는지에 주된 목적을 가진다. 이를 위해 작품 해석의 근거가 되는 그로테스크 담론과 현대적 의미를 살펴보고, 그의 작품에 적용함으로써 현재 무용계에서 활발하게 논의되고 있는 분열되고 확장되는 신체가 그로테스크와 어떻게 상호 관계를 갖는지 규명한다. 신체의 왜곡과 변형이 주요한 작동 요소로 나타난 , , , 를 분석 대상으로 선정하고 그로테스크의 주된 속성인 익숙함과 낯섦, 삶과 죽음, 미(美)와 추, 혐오와 매혹 등 서로 양립된 의미를 충돌시키는 것에 중점을 두고 고찰한다. 이를 근거로 컨템포러리 무용에서 신체 부위의 해체와 임의적인 결합을 통해 재구성된 신체가 비현실적인 허구의 세계를 표현하는 것이 아닌 은폐된 것들을 드러내고, 기존의 미적 시각을 재고하게 할 뿐만 아니라 경계를 넘어서는 새로운 가능성을 모색하고 있음을 확인하고자 한다.

• 한국전자통신학회논문지
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• 제18권6호
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• pp.1321-1330
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• 2023

본 연구는 증강현실에서 적용할 캐릭터 생성에서 단일 이미지를 통해 여러 객체에 대한 3D 자세 추정 문제를 연구한다. 기존 top-down 방식에서는 이미지 내의 모든 객체를 먼저 감지하고, 그 후에 각각의 객체를 독립적으로 재구성한다. 문제는 이렇게 재구성된 객체들 사이의 중첩이나 깊이 순서가 불일치 하는 일관성 없는 결과가 발생할 수 있다. 본 연구의 목적은 이러한 문제점을 해결하고, 장면 내의 모든 객체에 대한 일관된 3D 재구성을 제공하는 단일 네트워크를 개발하는 것이다. SMPL 매개변수체를 기반으로 한 인체 모델을 top-down 프레임워크에 통합이 중요한 선택이 되었으며, 이를 통해 거리 필드 기반의 충돌 손실과 깊이 순서를 고려하는 손실 두 가지를 도입하였다. 첫 번째 손실은 재구성된 사람들 사이의 중첩을 방지하며, 두 번째 손실은 가림막 추론과 주석이 달린 인스턴스 분할을 일관되게 렌더링하기 위해 객체들의 깊이 순서를 조정한다. 이러한 방법은 네트워크에 이미지의 명시적인 3D 주석 없이도 깊이 정보를 제공하게 한다. 실험 결과, 기존의 Interpenetration loss 방법은 MuPoTS-3D가 114, PoseTrack이 654에 비해서 본 연구의 방법론인 Lp 손실로 네트워크를 훈련시킬 때 MuPoTS-3D가 34, PoseTrack이 202로 충돌수가 크게 감소하는 것으로 나타났다. 본 연구 방법은 표준 3D 자세벤치마크에서 기존 방법보다 더 나은 성능을 보여주었고, 제안된 손실들은 자연 이미지에서 더욱 일관된 재구성을 실현하게 하였다.

• Archives of Plastic Surgery
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• 제36권4호
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• pp.437-444
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• 2009

Purpose: Transgender is a disorder of gender identity, who have appropriate chromosomal, hormonal and anatomical characteristics corresponding to their sexual phenotype but feel strongly with respect to their sexual identity, that they belong to the opposite sex. There is a persistence discomfort and sense of inappropriateness about one's assigned sex in a person who has reached puberty. Transgender is a psychiatric problem, but surgical method provides more satisfactory adjustment for patients. In gender reassignment surgery for female to male transgender, mastectomy, nipple reduction, hysterectomy, oophorectomy and phalloplasty are included. And as the final operation, recommended for scrotoplasty and artificial testes insertion. So we investigated the necessity and method of scrotoplasty in the final operation of female to male transgender. Method: The authors have long term follow-up of 75 cases female to male transgender during January, 1991 to February, 2008. Among them, 13 cases were evaluated in this study. During phalloplasty, the labium major skin preserved. And this labium majoral skin flap was made for the neoscrotum. At least six months later, artificial testes were inserted in neoscrotum with local anesthesia. Middle sized (3 cm diameter) artificial testes(silicon gel or carving soft silicone implant) were used because of the limitation of the neoscrotum. We evaluated the questionnaire and interview about the postoperative satisfaction in configuration of reconstructed scrotum, and the necessity of operation, the postoperative psychosocioeconomic improvement and limitation of body exposure activities such as swimming, public bathing. Results: Based on this study, satisfaction of reconstructed scrotum after scrotoplasty was improved(92%). The necessity of scrotoplasty was in 92.3% and the postoperative psychosocioeconomic well - being improvement was 77% in answers. Less limitation of activities requiring body exposure was 54% in answers. Most of the patients were satisfied with the results of surgical operation inspite of the operative procedure had some postoperative complications. Conclusion: This study was reported that the scrotoplasty in female to male transgender is not only a conversion of external genitalia but also an improvement of psychosocial state. Most patients sincerely hope to this operation, so we improve our surgical method for more good results.

• 대한치과교정학회지
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• 제43권4호
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• pp.168-177
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• 2013

Objective: In this study, we aimed to examine the relationship between chin deviation and the positional and morphological features of the mandible and to determine the factors that contributed to chin deviation in individuals with a unilateral cleft lip and palate (UCLP). Methods: Cone-beam computed tomography (CBCT) images of 28 adults with UCLP were analyzed in this study. Segmented three-dimensional temporomandibular fossa and mandible images were reconstructed, and angular, linear, and volumetric parameters were measured. Results: For all 28 individuals, the chin was found to deviate to the cleft side by 1.59 mm. Moreover, among these 28 individuals, only 7 showed distinct (more than 4 mm) chin deviation, which was toward the cleft side. Compared to the non-cleft side, the mandibular body length, frontal ramal inclination, and vertical position of the condyle were lower and inclination of the temporomandibular fossa was steeper on the cleft side. Furthermore, the differences in inclination of the temporomandibular fossa, mandibular body length, ramus length, and condylar volume ratio (non-deviated/deviated) were positively correlated with chin deviation. Conclusions: UCLP individuals show mild chin deviation to the cleft side. Statistical differences were noted in the parameters that represented positional and morphological asymmetries of the mandible and temporomandibular fossa; however, these differences were too small to indicate clinical significance.

• 복식
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• 제56권1호
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• pp.81-96
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• 2006

Fashion is very superficial. However, it is expressed through the culture that is a cause of internal change and therefore its contents are defined by the cultural features. In this study, to study the aesthetic properties of the French fashion, the internal fashion contents are defined according to the cultural characteristics of France and based on the definition, the external features are investigated. The cultural characteristic was analyzed based on the reference literatures on the French culture. Based on the cultural characteristics of France, the aesthetical properties of the contemporary French fashion can be analyzed as follows: ${\cdot}$Dualism is the internal contents of the French culture with multiple sources, and it implies that opposing values such as female and male, traditionalism and modernism, simplicity and decoration are coexisting. Simplicity is pursued but decorative elements are in harmony and new phase of time is reflected while certain style has lasted for a long period of time to become a tradition. Furthermore, a rational trend combining masculinity and femininity, simultaneously exist with a trend that emphasizes feminine image. ${\cdot}$Multiculturism is a mysterious feature that has adapted the oriental or other cultural factors into the forms, patterns, colors and material of costumes. It has also been reconstructed with the French and the modern tastes. ${\cdot}$Avant-gardism is pursuing a novel aesthetic value against the former value system. It recognizes the human body as an object of figurative arts therefore emphasizes the body with geometric shapes to deny the fixed-idea, or engraft new materials and technologies to express the futuristic aspects.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제33권4호
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• pp.337-345
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• 2011

Purpose: The purpose of this study was to define the relation of the degree of menton deviation and 3-D CT (computerized tomography) measurements of the glenoid fossa and the mandible, which are considered to have an influence on menton deviation. Methods: The CT images were obtained in 60 adults and these were transmitted to a computer and reconstructed using computer software. According to the degree of the menton deviation, which was measured on the posteroanterior cephalogram, the subjects were divided into the menton deviated group (30 adults) and the symmetry group (30 adults). A total of 11 measurements that might have an effect on menton deviation were determined and these were measured in the right and left sides using the function of 3-D measurement in the computer program. The 11 measurements consist of 6 measurements in the glenoid fossa (vertical position of the glenoid fossa and articular eminence, the sagittal position of the glenoid fossa and articular eminence, the depth of the glenoid fossa, and the anterior angle of the glenoid fossa), and 5 measurements in the mandible (ramus length, frontal ramal inclination, lateral ramal inclination, body length, body height). Results: The comparison of the differences between the menton deviated and symmetry groups and correlation analysis on the degree of menton deviation were carried out. The results of comparison of the right and the left difference between the menton deviated and symmetry groups showed that the vertical position and depth of the glenoid fossa were significantly increased in the menton deviated group. Conclusion: The results of the present study show that consideration of the shape and position of the glenoid fossa is necessary for making the diagnosis and administering proper treatment in facial asymmetry patients and especially growing patients.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제37권
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• pp.28.1-28.7
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• 2015

Background: The aim of this study was to present three-dimensional (3D) structural characteristics of the mandible in the hemifacial microsomia. The mandible has six distinct functional units, and its architecture is the sum of balanced growth of each functional unit and surrounding matrix. Methods: In order to characterize the mandibular 3D architecture of hemifacial microsomia, we analyzed the mandibular functional units of four hemifacial microsomia patients using the 3D reconstructed computed tomography (CT) images. And we compared the functional unit size between affected and non-affected side. Results: The length of condyle and angle showed significant differences between affected and non-affected sides. However, the length of mandibular body showed insignificant differences. The size differences between affected and non-affected side were observed at the condyle, angle, and body in descending order. Conclusions: This preliminary study suggests that the main etiopathogenic units are condyle and angle in the hemifacial microsomia mandible. Further investigation with the increased number of subjects will be helpful to establish treatment modality by etiopathogenic targeting of hemifacial microsomia.

• 한국정밀공학회지
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• 제26권12호
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• pp.138-145
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• 2009

Custom medical treatment is being widely adapted to lots of medical applications. A technology for 3D modeling is strongly required to fabricate medical implants for individual patient. Needs on true 3D CAD data of a patient is strongly required for tissue engineering and human body simulations. Medical imaging devices show human inner section and 3D volume rendering images of human organs. CT or MRI is one of the popular imaging devices for that use. However, those image data is not sufficient to use for medical fabrication or simulation. This paper mainly deals how to generate 3D geometry data from those medical images. A new image processing technology is introduced to reconstruct 3D geometry of a human body vacancy from the medical images. Then a surface geometry data is reconstructed by using Marching cube algorithm. Resulting CAD data is a custom 3D geometry data of human vacancy. This paper introduces a novel 3D reconstruction process and shows some typical examples with implemented software.

• 한국노년학
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• 제32권4호
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• pp.1181-1197
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• 2012

본 연구의 목적은 최근 외국에서 개발된 노화태도척도(AAQ)가 한국 노인에게 타당하게 적용가능한지를 검증하는 것이다. 이를 위해 서울, 경기, 충청권 노인 320명을 대상으로 3요인 24문항으로 구성된 노화태도척도(AAQ)에 대해 문항분석, 탐색적 요인분석, 수렴타당도 검증을 실시하였다. 분석 결과, 정규분포 가정에 위배되거나 요인계수가 낮은 3개의 문항이 삭제되어 총 21문항의 노화태도척도(AAQ-21)가 제시되었으며, 심리사회적 상실(psychosocial loss), 신체적 변화(physical change), 심리적 성장(psychological growth)의 3요인이 심리적 상실(psychological loss), 사회적 상실(social loss), 심신의 변화와 성장(change and growth in body and mind)의 3요인으로 재구성되었다. 21문항 노화태도척도의 내적신뢰도, 수렴타당도는 만족할 만한 수준이었다. 본 연구에서 제시한 21문항 노화태도척도(AAQ-21)는 다차원적 측면에서 노화태도를 측정할 뿐만 아니라 노화의 긍정적 측면 및 부정적 측면에 대한 태도까지 측정함으로써 노년학 연구자와 실무자들에게 과학적이고 체계적인 노화태도 측정방법을 제시할 것이다. 또한 노인복지현장 실무자는 물론 노인복지정책 개발자가 성공적 노화를 위한 프로그램과 정책마련을 위한 기초자료로 활용할 수 있을 것이다.