• 제목/요약/키워드: receiver operating characteristic analysis

검색결과 344건 처리시간 0.031초

Prognostic Accuracy of the Quick Sequential Organ Failure Assessment for Outcomes Among Patients with Trauma in the Emergency Department: A Comparison with the Modified Early Warning Score, Revised Trauma Score, and Injury Severity Score

  • Kang, Min Woo;Ko, Seo Young;Song, Sung Wook;Kim, Woo Jeong;Kang, Young Joon;Kang, Kyeong Won;Park, Hyun Soo;Park, Chang Bae;Kang, Jeong Ho;Bu, Ji Hwan;Lee, Sung Kgun
    • Journal of Trauma and Injury
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    • 제34권1호
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    • pp.3-12
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    • 2021
  • Purpose: To evaluate the severity of trauma, many scoring systems and predictive models have been presented. The quick Sequential Organ Failure Assessment (qSOFA) is a simple scoring system based on vital signs, and we expect it to be easier to apply to trauma patients than other trauma assessment tools. Methods: This study was a cross-sectional study of trauma patients who visited the emergency department of Jeju National University Hospital. We excluded patients under the age of 18 years and unknown outcomes. We calculated the qSOFA, the Modified Early Warning Score (mEWS), Revised Trauma Score (RTS), and Injury Severity Score (ISS) based on patients' initial vital signs and assessments performed in the emergency department (ED). The primary outcome was mortality within 14 days of trauma. We analyzed qSOFA scores using multivariate logistic regression analysis and compared the predictive accuracy of these scoring systems using the area under the receiver operating characteristic curve (AUROC). Results: In total, 27,764 patients were analyzed. In the multivariate logistic regression analysis of the qSOFA, the adjusted odds ratios with 95% confidence interval (CI) for mortality relative to a qSOFA score of 0 were 27.82 (13.63-56.79) for a qSOFA score of 1, 373.31 (183.47-759.57) for a qSOFA score of 2, and 494.07 (143.75-1698.15) for a qSOFA score of 3. In the receiver operating characteristic (ROC) curve analysis for the qSOFA, mEWS, ISS, and RTS in predicting the outcomes, for mortality, the AUROC for the qSOFA (AUROC [95% CI]; 0.912 [0.871-0.952]) was significantly greater than those for the ISS (0.700 [0.608-0.793]) and RTS (0.160 [0.108-0.211]). Conclusions: The qSOFA was useful for predicting the prognosis of trauma patients evaluated in the ED.

노인과 비노인 외상환자의 손상중증도에 따른 특성 비교 (Comparison of the Characteristics according to Injury Severity Score between Elderly and Non-elderly with Trauma)

  • 김현주;김윤경
    • 한국보건간호학회지
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    • 제32권2호
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    • pp.304-318
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    • 2018
  • Purpose: This study examined the characteristic of the Injury Severity Score (ISS) of Korean geriatric patients with a traumatic injury in a nationally representative sample to determine the optimal cutoff of ISS of mortality according to age. Methods: The subjects were 3,018 non-elderly patients and 1,584 elderly patients with an ISS and Korean Triage and Acuity Scale (KTAS) in 2016 from the data of the Health Insurance Review and Assessment Service. The traumatic characteristics of the elderly and non-elderly were compared by stratifying the ISS. Receiver Operating Characteristic (ROC) curve analysis was used to find the optimal cutoff of ISS of mortality according to age. Results: The elderly were more prone to severe trauma than the non-elderly were. The distribution of KTAS grades was lower, even though the severity of ISS was as high as that of the non-elderly. The optimal cutoff score of the ISS for mortality in the ROC curve was lower in elderly over 65 years than in the other age group. Conclusion: The elderly are more prone to severe trauma and death than non-elderly, even though their ISS is low. Therefore, a strategy to prevent elderly from experiencing serious trauma and managing their geriatric trauma actively is needed.

여대생의 비만평가 방법으로서의 목둘레 (Neck Circumference as a Measure for Identifying Obesity in Female College Students)

  • 정승교
    • 기본간호학회지
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    • 제12권3호
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    • pp.347-353
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    • 2005
  • Purpose: The purpose of this study was to identify whether neck circumference might be correlated with other obesity indices and to determine the neck circumference cutoff level for obesity in female college students. Method: The data were obtained by measuring other anthropometric indices including BMI and neck circumference from 325 female college students in J city, Chungbuk Province. Receiver Operating Characteristic curve(ROC curve) analysis was used to find the optimal neck circumference cutoff level against BMI $25kg/m^2$. Results: The mean BMI was $21.4kg/m^2$, and the prevalence of obesity was 12.6%. Neck circumference was significantly correlated with body weight, BMI, waist circumference, hip circumference, waist to hip ratio, % body fat, triceps skinfold thickness, systolic and diastolic blood pressure. Neck circumference of 31.95cm was the best cutoff level for determining female students with a BMI over $25kg/m^2$, and the characteristic was acceptable with 97.6% sensitivity and 85.6% specificity. Conclusions: Neck circumference was strongly correlated with the other conventional obesity indices. Female college students with neck circumference over 31.95cm require an additional evaluation of obesity.

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A Validation Study of the Korean Child Behavior Checklist 1.5-5 in the Diagnosis of Autism Spectrum Disorder and Non-Autism Spectrum Disorder

  • Cho, Han Nah;Ha, Eun Hye
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • 제30권1호
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    • pp.9-16
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    • 2019
  • Objectives: The purpose of this study was to analyze the discriminant validity and the clinical cut off scores of the Child Behavior Checklist 1.5-5 (CBCL 1.5-5) in the diagnosis of autism spectrum disorder (ASD) and non-ASD. Methods: In total, 104 ASD and 441 non-ASD infants were included in the study. T-test, discriminant analysis, receiver operating characteristic (ROC) curve analysis, and odds ratio analysis were performed on the data. Results: The discriminant validity was confirmed by mean differences and discriminant analysis on the subscales of Emotionally reactive, Somatic complaints, Withdrawn, Sleep problems, Attention problems, Aggressive behavior, Internalizing problems, Externalizing problems, and Total problems, along with the Diagnostic and Statistical Manual of Mental Disorders (DSM)-oriented scales between the two groups. ROC analysis showed that the following subscales significantly separated ASD from normal infants: Emotionally reactive, Somatic complaints, Withdrawn, Sleep problems, Attention problems, Aggressive behavior, Internalizing problems, Externalizing problems, Total problems, and DSM pervasive developmental problems. Moreover, the clinical cut off score criteria adopted in the Korean-CBCL 1.5-5 were shown to be valid for the subscales Withdrawn, Internalizing problems, Externalizing problems, Total problems, and DSM pervasive developmental problems. Conclusion: The subscales of Withdrawn, Internalizing problems, Externalizing problems, Total problems, and DSM pervasive developmental problems significantly discriminated infants with ASD.

한국 노인의 외로움 측정도구 개발 (Development of the Korean Geriatric Loneliness Scale (KGLS))

  • 이시은
    • 대한간호학회지
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    • 제49권5호
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    • pp.643-654
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    • 2019
  • Purpose: The purpose of this study was to develop and psychometrically test the Korean Geriatric Loneliness Scale (KGLS). Methods: The initial items were based on in-depth interviews with 10 older adults. Psychometric testing was then conducted with 322 community-dwelling older adults aged 65 or older. Content, construct, and criterion-related validity, classification in cutoff point, internal consistency reliability, and test-retest reliability were used for the analysis. Results: Exploratory factor analysis showed three factors, including 15 items explaining 91.6% of the total variance. The three distinct factors were loneliness associated with family relationships (34.3%), social loneliness (32.4%), and a lack of belonging (24.9%). As a result of confirmatory factor analysis, 14 items in the three-factor structure were validated. Receiver operating characteristic analysis demonstrated that the KGLS' cutoff point of 32 was associated with a sensitivity of 71.0%, specificity of 80.2%, and area under the curve of .83. Reliability, as verified by the test-retest intraclass correlation coefficient, was .89, and Cronbach's ${\alpha}$ was .90. Conclusion: As its validity and reliability have been verified through various methods, the KGLS can contribute to assessing loneliness in South Korean older adults.

Aberrant Methylation of Genes in Sputum Samples as Diagnostic Biomarkers for Non-small Cell Lung Cancer: a Meta-analysis

  • Wang, Xu;Ling, Li;Su, Hong;Cheng, Jian;Jin, Liu
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권11호
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    • pp.4467-4474
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    • 2014
  • Background: We aimed to comprehensively review the evidence for using sputum DNA to detect non-small cell lung cancer (NSCLC). Materials and Methods: We searched PubMed, Science Direct, Web of Science, Chinese Biological Medicine (CBM), Chinese National Knowledge Infrastructure (CNKI), Wanfang, Vip Databases and Google Scholar from 2003 to 2013. The meta-analysis was carried out using a random-effect model with sensitivity, specificity, diagnostic odd ratios (DOR), summary receiver operating characteristic curves (ROC curves), area under the curve (AUC), and 95% confidence intervals (CI) as effect measurements. Results: There were twenty-two studies meeting the inclusion criteria for the meta-analysis. Combined sensitivity and specificity were 0.62 (95%CI: 0.59-0.65) and 0.73 (95%CI: 0.70-0.75), respectively. The DOR was 10.3 (95%CI: 5.88-18.1) and the AUC was 0.78. Conclusions: The overall accuracy of the test was currently not strong enough for the detection of NSCLC for clinical application. Dscovery and evaluation of additional biomarkers with improved sensitivity and specificity from studies rated high quality deserve further attention.

Racial and Socioeconomic Disparities in Malignant Carcinoid Cancer Cause Specific Survival: Analysis of the Surveillance, Epidemiology and End Results National Cancer Registry

  • Cheung, Rex
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권12호
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    • pp.7117-7120
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    • 2013
  • Background: This study hypothesized living in a poor neighborhood decreased the cause specific survival in individuals suffering from carcinoid carcinomas. Surveillance, Epidemiology and End Results (SEER) carcinoid carcinoma data were used to identify potential socioeconomic disparities in outcome. Materials and Methods: This study analyzed socioeconomic, staging and treatment factors available in the SEER database for carcinoid carcinomas. The Kaplan-Meier method was used to analyze time to events and the Kolmogorov-Smirnov test to compare survival curves. The Cox proportional hazard method was employed for multivariate analysis. Areas under the receiver operating characteristic curves (ROCs) were computed to screen the predictors for further analysis. Results: There were 38,546 patients diagnosed from 1973 to 2009 included in this study. The mean follow up time (S.D.) was 68.1 (70.7) months. SEER stage was the most predictive factor of outcome (ROC area of 0.79). 16.4% of patients were un-staged. Race/ethnicity, rural urban residence and county level family income were significant predictors of cause specific survival on multivariate analysis, these accounting for about 5% of the difference in actuarial cause specific survival at 20 years of follow up. Conclusions: This study found poorer cause specific survival of carcinoid carcinomas of individuals living in poor and rural neighborhoods.

퍼지관계 기법과 인공신경망 기법을 이용한 포항지역의 산사태 취약성 예측 기법 비교 연구 (A Comparative Study of Fuzzy Relationship and ANN for Landslide Susceptibility in Pohang Area)

  • 김진엽;박혁진
    • 자원환경지질
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    • 제46권4호
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    • pp.301-312
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    • 2013
  • 산사태는 지형, 지질, 임상, 토양 등과 같은 다양한 요인들이 복합적으로 작용하여 발생한다. 따라서 산사태 발생위치와 산사태 유발 요인 사이의 상관관계를 파악할 수 있는 다양한 분석 기법이 사용되고 있으며 본 연구에서는 산사태 위험지역을 정량적으로 예측할 수 있는 효과적인 기법을 제안하고자 퍼지관계 기법과 인공신경망 기법을 이용하여 포항지역의 산사태 취약성을 분석하였다. 취약성 분석을 위해 먼저 산사태 위치를 파악하여 현황도를 작성하였으며, 산사태 발생과 관련 있는 11개의 요인들에 대한 공간 데이터베이스를 구축하였다. 퍼지관계 기법에서는 cosine amplitude method를 이용해 각 요인 별 퍼지 소속 함수 값을 획득하고 퍼지관계 함수 연산을 이용하여 취약성도를 작성하였다. 인공신경망 기법에서는 오류 역전파 알고리즘을 이용하여 산사태와 관련 요인들 간의 상대적 가중치를 결정하고 취약성도를 작성하였다. 두 기법으로 도출된 산사태 취약성도의 ROC(Receiver Operating Characteristic)와 AUC(Area Under the Curve)를 통한 검증 결과는 82.18%와 87.4%로 나타났다. 퍼지 관계 및 인공신경망 기법 모두 높은 예측 정확도를 보여 취약성 분석 기법으로서의 적용 가능성이 있는 것으로 분석되었다. 한편 본 연구지역의 경우 인공신경망 기법이 퍼지관계 기법에 비해 좀 더 나은 예측 정확도를 보이는 것으로 분석되었다.

ECG 기반의 운전자별 인지 부하 평가 방법 개발 (Development of an Evaluation Method for a Driver's Cognitive Workload Using ECG Signal)

  • 홍원기;이원섭;정기효;이백희;박장운;박수완;박윤숙;손준우;박세권;유희천
    • 대한산업공학회지
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    • 제40권3호
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    • pp.325-332
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    • 2014
  • High cognitive workload decreases a driver's ability of judgement and response in traffic situation and could result in a traffic accident. Electrocardiography (ECG) has been used for evaluation of drivers' cognitive workload; however, individual differences in ECG response corresponding to cognitive workload have not been fully considered. The present study developed an evaluation method of individual driver's cognitive workload based on ECG data, and evaluated its usefulness through an experiment in a driving simulator. The evaluation method developed by the present study determined the optimal ECG evaluation condition for individual participant by analysis of area under the receiver operating characteristic curve (AUC) for various conditions (total number of conditions = 144) in terms of four aspects (ECG measure, window span, update rate, and workload level). AUC analysis on the various conditions showed that the optimal ECG evaluation condition for each participant was significantly different. In addition, the optimal ECG evaluation condition could accurately detect changes in cognitive workload for 47% of the total participants (n = 15). The evaluation method proposed in the present study can be utilized in the evaluation of individual driver's cognitive workload for an intelligent vehicle.

다시기 원격탐사자료 기반 무감독 변화탐지의 계절적 영향 제거 (Seasonal Effects Removal of Unsupervised Change Detection based Multitemporal Imagery)

  • 박홍련;최재완;오재홍
    • 한국측량학회지
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    • 제36권2호
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    • pp.51-58
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    • 2018
  • 최근, 다양한 위성센서가 개발되면서 다시기 위성영상의 취득이 용이해지고 있다. 이에 따라, 재난/재해, 국토모니터링 등과 같은 활용분야에 다시기 위성영상을 적용하기 위한 변화탐지 기법에 대한 연구들이 수행되고 있다. 특히, 빠른 시간 내에 변화지역의 추출이 가능한 무감독 변화탐지 기법의 개발과 관련된 연구들이 수행되고 있지만, 계절적 변화 등과 같은 방사적 차이로 인해 오탐지가 발생하는 단점이 있다. 따라서, 본 연구에서는 무감독 변화탐지 기법 중의 하나인 $S^2CVA$ 기법을 적용하여 생성한 변화방향 벡터를 이용하여 계절적 영향으로 인한 오탐지를 감소시키고자 하였다. 이를 위하여, 동일한 계절을 가지는 RapidEye 위성영상과 다른 계절에 촬영된 RapidEye 위성 영상에 $S^2CVA$ 기법을 적용하였으며, $S^2CVA$의 변화방향벡터가 계절적 영향에 따른 오탐지를 제거할 수 있는지를 분석하였다. 정량적 평가를 위해 변화탐지 결과의 ROC 곡선과 AUC 분석을 통해 기존의 방법에 비해 변화탐지 성능이 향상된 것을 확인하였다.